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The Attractive Factors Analysis of Taiwanese Bed&Breakfast on Travel Web sites
Hsiao-li Lin,Kuohsiang Chen,Meng-dar Shieh,Chun-Heng Ho 세계문화관광학회 2010 Conference Proceedings Vol.11 No.0
Due to raising population of tourism and popular experiential tour, more and more people have invested in building their dreamlike Bed & Breakfast (B&Bs). However, B&B industry faces a tight situation because of the growth of B&Bs, especially on competitive travel website. In particular, we can find out a variety of B&Bs‘ images at the same page of travel websites At limited web space and a variety of competitors, how to attract consumers to click it is the primary issue. What kind of image, information, or keywords may influence customers’ decision? This study discusses the attractive factors of Taiwanese B&B on travel websites and the result information can help B&B hosts develop effective advertising and promotional plans. In this study, we chose 127 B&B images which show the first sight of B&Bs from travel websites. The research was divided into three steps. In the first step, Evaluation Grid Method (EGM) was applied to construct attractive factors of B&Bs from interviews. In the second st ep, the hierarchical diagram of EGM was further adopted to organize a questionnaire. A nd then, quantitative type I method was applied to analyze the data collected from the questionnaires. A total of 37 valid samples were collected in this experiment. The main impact factors of four attractiveness aspects of B&Bs information were obtained: "theme style" for " distinguishing characters " aspect, "reunion" for " leisure atmosphere ", "uni que style" for " style of B&B ", and " word of mouth‖. for "satisfaction" aspect. In the third step, cluster analysis was employed to identify the visitor groups as following: peo ple who like characteristic things and relax environment, people who enjoy interacting w ith their friends, family and B&B hosts, and people who are interesting in making com parison of B&Bs and book B&Bs online habitually. The findings of this study may assi st B&B host in promotion and advertising on travel websites more efficiency.
Experiences of Family of Patient with Newly Diagnosed Advanced Terminal Stage Hepatocellular Cancer
Shih, Whei-Mei Jean,Hsiao, Ping-Ju,Chen, Min-Li,Lin, Mei-Hsiang Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.8
Background: Hepatocellular carcinoma (HCC) is the most common primary liver cancer and the third leading cause of cancer-related death worldwide due to its generally poor prognosis. Caregiver burden for liver cancer cases is higher than with other cancer and needs especial attention. Methods: To explore the experiences of families of patients with newly diagnosed advanced terminal stage hepatocellular cancer by interview. Results: Nine participants were recruited in this study. Content analysis of the interviews revealed four themes: blaming oneself, disrupting the pace of life, searching all possible regimens, and not letting go. Conclusions: This study provides new insight into the needs and support of family members especially when they are facing loved ones with newly diagnosed advanced terminal stage HCC. These results will inform future supportive care service development and intervention research aimed at providing assistance in reducing unmet supportive care needs and psychological distress of these family members.
Chung-Ze Wu,Dee Pei,An-Tsz Hsieh,Kun Wang,Jiunn-Diann Lin,Li-Hsiu Lee,Yi-Min Chu,Fone-Ching Hsiao,Chun Pei,Te-Lin Hsia 대한약학회 2010 Archives of Pharmacal Research Vol.33 No.3
The traditional sulfonylureas with long half-lives have sustained stimulatory effects on insulin secretion compared to the short-acting insulin secretagogue. In this study, we used the frequently sampled intravenous glucose tolerance test (FSIGT) to evaluate the insulin sensitivity (IS), glucose sensitivity (SG), and acute insulin response after glucose load (AIRg) after 4months treatment with either gliclazide or repaglinide. The design of study was randomizedcrossover. We enrolled 20 patients with new-onset type 2 diabetes (mean age, 49.3 years). Totally three FSIGTs were performed, one before and one after each of the two treatment periods as aforementioned. No significant differences in fasting plasma glucose, insulin, body mass index, blood pressure, glycated hemoglobin, or lipids were noted between the two treatments. After the repaglinide treatment, higher AIRg, lower IS, and lower SG were noted, but they did not reach statistical significance. The disposal index (DI) was also not significantly different between the two treatments. In conclusion, since non-significantly higher DI, AIRg, lower IS and SG were noted after repaglinide treatment, it might be a better treatment for diabetes, relative to gliclazide.
Wang Hui-Ching,Moi Sin-Hua,Chan Leong-Perng,Wu Chun-Chieh,Du Jeng-Shiun,Liu Pei-Lin,Chou Meng-Chun,Wu Che-Wei,Huang Chih-Jen,Hsiao Hui-Hua,Pan Mei-Ren,Chen Li-Tzong 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Personalized genetic profiling has focused on improving treatment efficacy and predicting risk stratification by identifying mutated genes and selecting targeted agents according to genetic testing. Therefore, we evaluated the role of genetic profiling and tumor mutation burden (TMB) using next-generation sequencing in patients with head and neck squamous cell carcinoma (HNSC). The relapse mutation signature (RMS) and chromatin remodeling mutation signature (CRMS) were explored to predict the risk of relapse in patients with HNSC treated with concurrent chemoradiotherapy (CCRT) with platinum-based chemotherapy. Patients in the high RMS and CRMS groups showed significantly shorter relapse-free survival than those in the low RMS and CRMS groups, respectively (p < 0.001 and p = 0.006). Multivariate Cox regression analysis showed that extranodal extension, CCRT response, and three somatic mutation profiles (TMB, RMS, and CRMS) were independent risk predictors for HNSC relapse. The predictive nomogram showed satisfactory performance in predicting relapse-free survival in patients with HNSC treated with CCRT.