White-Matter Hyperintensities and Lacunar Infarcts Are Associated with an Increased Risk of Alzheimer’s Disease in the Elderly in China

Shuai Ye,Shuyang Dong,Jun Tan,Le Chen,Hai Yang,Yang Chen,Zeyan Peng,Yingchao Huo,Juan Liu,Mingshan Tang,Yafei Li,Huadong Zhou,Yong Tao 대한신경과학회 2019 Journal of Clinical Neurology Vol.15 No.1

Background and Purpose This study investigated the contribution of white-matter hyperintensities (WMH) and lacunar infarcts (LI) to the risk of Alzheimer’s disease (AD) in an elderly cohort in China. Methods Older adults who were initially cognitively normal were examined with MRI at baseline, and followed for 5 years. WMH were classified as mild, moderate, or severe, and LI were classified into a few LI (1 to 3) or many LI (≥4). Cognitive function was assessed using the Mini Mental State Examination and the Activities of Daily Living scale. Results Among the 2,626 subjects, 357 developed AD by the end of the 5-year follow-up period. After adjusting for age and other potential confounders, having only WMH, having only LI, and having both WMH and LI were associated with an increased risk of developing AD compared with having neither WMH nor LI. Moderate and severe WMH were associated with an increased risk of developing AD compared with no WMH. Furthermore, patients with many LI had an increased risk of developing AD compared with no LI. Conclusions Having moderate or severe WMH and many LI were associated with an increased risk of developing AD, with this being particularly striking when both WMH and LI were present.

Dual-Band Antenna with OAM Mode Radiated by Ground Plane

Li Yuheng,Yang Guang,Li Weiwen,Liu Qing Huo 한국전자파학회 2023 Journal of Electromagnetic Engineering and Science Vol.23 No.3

Antennas that radiate orbital angular momentum (OAM) modes are usually large and have complex structures. In this paper, in combination with characteristic mode analysis, the ground plane is used as the OAM wave radiator. To excite degenerate modes of the ground plane with phase quadrature by using a single-fed structure, two bent metal strips with grounded ends are introduced around the rectangular ground plane, and a corner of one of the bent strips is set as the feeding point. For ground radiators, a first-order OAM mode is generated at the high-frequency end by synthesizing the degenerate modes. In case of the bent side strip, an inverted-F antenna that operates in the low-frequency mode is formed. This compact antenna has dual-band characteristics and facilitates simple feeding, which makes it suitable for mobile terminal applications.

The comparison between carboxyl, amido and hydroxy group in influencing electrorheological performance

Li Huo,Jun-Ran Li,Fu-Hui Liao 한국유변학회 2011 Korea-Australia rheology journal Vol.23 No.1

Three kinds of electrorheological (ER) materials with carboxyl, amido and hydroxyl group, respectively,were synthesized by a simple adsorption method. The powder of silicon dioxide as a substrate of the materials,as well as terephthalic acid [p-C_6H_4(COOH)_2, abbr.: phen-COOH], p-phenylenediamine [p-C_6H_4(NH_2)_2, abbr.: phen-NH_2] and hydroquinone [p-C_6H_4(OH)_2, abbr.: phen-OH] were chosen as starting materials. The ER properties of suspensions of the materials in silicon oil were studied. The suspension of the material adsorbing phen-COOH reveals the highest ER activity, the relative shear stress of the suspension (25 wt%), τ_r(=τ_E/τ_0, τ_E and τ_0 are the shear stresses at electric field strengths of E=4.2 and 0 kV/mm, respectively), reaches 220 under a DC electric field at a shear rate of 14.5 s^(−1). The shear stress of the suspension of the material adsorbing phen-NH2 is the largest at an high electric field strength. The ER activity of the material adsorbing phen-OH is the lowest among the three materials. The molecule structure is an importance factor in influencing ER performance of the materials for similar compounds with different polar function groups. The relationship between the ER activity and dielectric property of the materials was discussed.

해외직접투자가 경제성장에 미치는 영향: 4 패널 분위수회귀분석에 기반한 실증분석

( Li Juan Huo ) 연세대학교 경제연구소 2015 延世經濟硏究 Vol.22 No.1

20세기 90년대부터 해외직접투자는 신속히 증가하는 추세를 보였다. 세계각국 특히 저개발국들은 관세 저하와 보조금 지불 등 방법으로 해외직접투자를 유치하기 위해 경쟁하고 있다. 본 논문에서는 기구변량 분위수회귀분석으로 패널 데이터의 고정효과를 분석함으로써 해외직접투자가 경제성장에 미치는 영향에 대해 고찰하였다. 실증분석 결과에 의하면 해외직접투자는 저개발국의 경제성장에 정의 영향을 미치며 그 영향은 GDI보다 더 크다. FDI has increased substantially since the 1980s. Countries, especially under-developed countries, competes with each other to attract FDI by reducing tax and granting subsidies. We propose using instrumental variable quantile regression for panel data with fixed effects to analyze the impact of FDI on economic growth. Our empirical findings shows that FDI positively relates to economic growth in under-developed countries, and the contribution of FDI on growth is even greater than GDI.

Activation of antiferromagnetic domain switching in exchange-coupled Fe/CoO/MgO(001) systems

Li, Q.,Chen, G.,Ma, T. P.,Zhu, J.,N'Diaye, A. T.,Sun, L.,Gu, T.,Huo, Y.,Liang, J. H.,Li, R. W.,Won, C.,Ding, H. F.,Qiu, Z. Q.,Wu, Y. Z. American Physical Society 2015 Physical review. B, Condensed matter and materials Vol.91 No.13

The comparison between carboxyl, amido and hydroxy group in influencing electrorheological performance

Huo, Li,Li, Jun-Ran,Liao, Fu-Hui 한국유변학회 2011 Korea-Australia rheology journal Vol.23 No.1

Three kinds of electrorheological (ER) materials with carboxyl, amido and hydroxyl group, respectively, were synthesized by a simple adsorption method. The powder of silicon dioxide as a substrate of the materials, as well as terephthalic acid [$p-C_6H_4(COOH)_2$, abbr.: phen-COOH], p-phenylenediamine [$p-C_6H_4(NH_2)_2$, abbr.: $phen-NH_2$] and hydroquinone [$p-C_6H_4(OH_2)_2$, abbr.: phen-OH] were chosen as starting materials. The ER properties of suspensions of the materials in silicon oil were studied. The suspension of the material adsorbing phen-COOH reveals the highest ER activity, the relative shear stress of the suspension (25 wt%), ${\tau}_r(={\tau}_E/{\tau}_0,\;{\tau}_E\;and\;{\tau}_0$ are the shear stresses at electric field strengths of E=4.2 and 0 kV/mm, respectively), reaches 220 under a DC electric field at a shear rate of $14.5s^{-1}$. The shear stress of the suspension of the material adsorbing $phen-NH_2$ is the largest at an high electric field strength. The ER activity of the material adsorbing phen-OH is the lowest among the three materials. The molecule structure is an importance factor in influencing ER performance of the materials for similar compounds with different polar function groups. The relationship between the ER activity and dielectric property of the materials was discussed.

Molecular Cloning, Identification and Characteristics of a Novel Isoform of Carbamyl Phosphate Synthetase I in Human Testis

Huo, Ran,Zhu, Hui,Lu, Li,Ying, Lanlan,Xu, Min,Xu, Zhiyang,Li, Jianmin,Zhou, Zuomin,Sha, Jiahao Korean Society for Biochemistry and Molecular Biol 2005 Journal of biochemistry and molecular biology Vol.38 No.1

A gene coding a novel isoform of carbamyl phosphate synthetase I (CPS1) was cloned from a human testicular library. As shown by cDNA microarray hybridization, this gene was expressed at a higher level in human adult testes than in fetal testes. The full length of its cDNA was 3831 bp, with a 3149 bp open reading frame, encoding a 1050-amino-acid protein. The cDNA sequence was deposited in the GenBank (AY317138). Sequence analysis showed that it was homologous to the human CPS1 gene. The putative protein contained functional domains composing the intact large subunit of carbamoyl phosphate synthetase, thus indicated it has the capability of arginine biosynthesis. A multiple tissue expression profile showed high expression of this gene in human testis, suggesting the novel alternative splicing form of CPS1 may be correlated with human spermatogenesis.

Reviews on innovations and applications in structural health monitoring for infrastructures

Li, Hong-Nan,Yi, Ting-Hua,Ren, Liang,Li, Dong-Sheng,Huo, Lin-Sheng Techno-Press 2014 Structural monitoring and maintenance Vol.1 No.1

The developments and implementations of the structural health monitoring (SHM) system for large infrastructures have been gradually recognized by researchers, engineers and administrative authorities in the last decades. This paper summarizes an updated review on innovations and applications in SHM for infrastructures carried out by researchers at Dalian University of Technology. Invented sensors and data acquisition system are firstly briefly described. And then, some proposed theories and methods including the sensing technology, sensor placement method, signal processing and data fusion, system identification and damage detection are discussed in details. Following those, the activities on the standardization of SHM and several case applications on specific types of structure are reviewed. Finally, existing problems and promising research efforts in the field of SHM are given.

Experimental and numerical study on large-curvature curved composite box girder under hogging moment

Li Zhu,Jia J. Wang,Guan Y. Zhao,Xue J. Huo,Xuan Li 국제구조공학회 2020 Steel and Composite Structures, An International J Vol.37 No.2

Curved steel-concrete composite box girder has been widely adopted in urban overpasses and ramp bridges. In order to investigate its mechanical behavior under complicated and combined bending, shear and torsion load, two large-curvature composite box girders with interior angles of 25º and 45º were tested under static hogging moment. Based on the strain and deflection measurement on critical cross-sections during the static loading test, the failure mode, cracking behavior, load-displacement relationship, and strain distribution in the steel plate and rebar were investigated in detail. The test result showed the large-curvature composite box girders exhibited notable shear lag in the concrete slab and steel girder. Also, the constraint torsion and distortion effect caused the stress measured at the inner side of the composite beam to be notably higher than that of the outer side. The strain distribution in the steel web was approximately linear; therefore, the assumption that the plane section remains plane was approximately validated based on strain measurement at steel web. Furthermore, the full-process non-linear elaborate finite element (FE) models of the two specimens were developed based on commercial FE software MSC.MARC. The modeling scheme and constitutive model were illustrated in detail. Based on the comparison between the FE model and test results, the FE model effectively simulated the failure mode, the load-displacement curve, and the strain development of longitudinal rebar and steel girder with sufficient accuracy. The comparison between the FE model and the test result validated the accuracy of the developed FE model.

Effect of oxygen non-stoichiometry on magnetic and electrical transport properties of La0.67Sr0.33MnO3

Huo Guoyan,Su Qian,Li He,Li Zhenxing,Chang Yating 한국물리학회 2020 Current Applied Physics Vol.20 No.6

The effect of oxygen deficiency and oxygen excess on the magnetic and electrical transport properties of La0.67Sr0.33MnO3 has been investigated. The thermal and isothermal magnetization measurement results show that the Curie temperature and saturation magnetization of oxygen deficient sample (defined as A) are higher than those oxygen excess sample (defined as B). The electrical resistivity of A is lower than that of B in studied temperature range. The magnetoresistance (MR) of B is larger than that of A in the temperature range from 280 to 360 K, which agrees with the magnetic field needed full spin polarization at room temperature. The colossal MR (CMR) around transition temperature from ferromagnetic metal to paramagnetic insulator (TMI) for A is larger than that for B, which arises from assistance of stronger lattice deformation for A.