Comparison of trophic factors changes in the hippocampal CA1 region between the young and adult gerbil induced by transient cerebral ischemia.

Yan, Bing Chun,Park, Joon Ha,Kim, Sung Koo,Choi, Jung Hoon,Lee, Choong Hyun,Yoo, Ki-Yeon,Kwon, Young-Geun,Kim, Young-Myeong,Kim, Jong-Dai,Won, Moo-Ho Kluwer Academic/Plenum Publishers 2012 Cellular and molecular neurobiology Vol.32 No.8

<P>In the present study, we investigated neuronal death/damage in the gerbil hippocampal CA1 region (CA1) and compared changes in some trophic factors, such as brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF) and vascular endothelial growth factor (VEGF), in the CA1 between the adult and young gerbils after 5 min of transient cerebral ischemia. Most of pyramidal neurons (89%) were damaged 4 days after ischemia-reperfusion (I-R) in the adult; however, in the young, about 59% of pyramidal neurons were damaged 7 days after I-R. The immunoreactivity and levels of BDNF and VEGF, not GDNF, in the CA1 of the normal young were lower than those in the normal adult. Four days after I-R in the adult group, the immunoreactivity and levels of BDNF and VEGF were distinctively decreased, and the immunoreactivity and level of GDNF were increased. However, in the young group, all of their immunoreactivities and levels were much higher than those in the normal young group. From 7 days after I-R, all the immunoreactivities and levels were apparently decreased compared to those of the normal adult and young. In brief, we confirmed our recent finding: more delayed and less neuronal death occurred in the young following I-R, and we newly found that the immunoreactivities of trophic factors, such as BDNF, GDNF, and VEGF, in the stratum pyramidale of the CA1 in the young gerbil were much higher than those in the adult gerbil 4 days after transient cerebral ischemia.</P>

수입각증후군에 의한 급성 복증 1례

정은욱,지삼룡,이영태,박지훈,김동기,제인수,채두근,박성재,박은택,이연재,이상혁,설상영,정정명 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Afferent loop syndrome is an uncommon complication of a gastrectomy and Billroth Ⅱ reconstruction. It may cause symtoms at any time from the first postoperative day to many years after the gastrectomy. Afferent loop syndrome is characterized by abdominal pain, vomiting and elevation of serum amylase. Thus, it is difficult to differentiate afferent loop syndrome from other cause of acute pancreatitis. However, the history of gastrectomy can be an important clue for diagnosing afferent loop syndrome. We experienced one case of chronic afferent loop syndrome with acute pancreatitis. After appropriate management, the abdominal pain disappeared and serum amylase level decreased. We report this case with a review of relevant literatures.

지역순환형 자립발전전략

이성근 ( Seong Keun Lee ),나중규 ( Jung Gyu Na ),최영은 ( Young Eun Choi ),임규채 ( Gyu Chae Im ),최용준 ( Yong Jun Choi ),이정미 ( Jungmi Lee ),홍근석 ( Geun Seok Hong ) 영남대학교 한국균형발전연구소(구 영남대학교 영남지역발전연구소) 2013 한국균형발전연구 Vol.4 No.1

최근 우리나라의 지역개발이나 정책에 있어 과거의 중앙정부 중심, 물적 성장 중심의 개발 패러다임에서 벗어나 자립적 역량강화, 지역 간 연계협력, 융합화 등이 강조되고 있다. 이에 본 연구의 목적은 지방자치제가 실시되었으나 지방의 자치기반이 취약하여 지역간 불균형 발전이 심화되는 가운데, 박근혜정부의 출범과 함께 최근 국내외적으로 변화하고 있는 지역발전의 패러다임에 직면하여 지방분권과 균형발전에 토대를 둔 지역 주도의 자립적 지역발전을 이루기 위한 구체적 방안을 제시하는 데 있다. 이를 위해 시대적 요구와 필요성을 절감하고, 지역적 차원에서 창조경제에 기반한 새로운 지역발전 패러다임으로서 국민대통합과 지역균형발전을 지향하는 「지역순환형 자립발전모델」을 제시하였다. 이는 궁극적으로 국내외 패러다임의 변화를 체계적 이론적 틀로써 통합하고 실질적으로 적용하기 위한 것으로 지역을 중심으로 사람을 키우고, 청년을 살게 하고, 사람이 모이게 하는 것을 의미한다. 이를 달성하기 위한 구체적 전략으로서 선순환 전략과 자립전략을 제시하였다. 첫째, 지역순환형 자립발전의 토대가 되는 자립전략으로서 지역발전의 가치와 목적을 ‘지역역량강화(Competency)’. ‘연계협력(Cooperation)’, ‘융합(Convergence)’의 3C전략을 제시하였다. 둘째, 지역순환형 자립발전을 달성하기 위한 선순환 진흥전략으로서 지역교육 진흥, 지역산업진흥, 지역문화예술진흥, 지역복지진흥, 지역창조와 재생을 제시하였다. 첫 번째 전략은 우수 인재양성을 통한 지역교육 진흥(振興)이다 교육부문 진흥을 통해 우수한 인재를 양성하고 지역에 공급하는 시스템을 구축하는 것이다. 둘째, 일자리 창출을 위한 지역산업진흥(振興) 이다, 즉 산업부문 진흥을 통해 청년일자리 창출 및 역동적 지역창출에 기여하는 것이다. 셋째, 지역문화와 예술 기반 구축 및 역량 강화를 통해 지방문화예술을 진흥해 나가야 한다. 넷째, 지역복지역랑 강화를 위한 지역복지 진흥(振興) 이다. 지역복지 진흥을 통해 지역 복지 예산 및 인프라 구축 등을 통해 서민들이 피부로 느낄 수 있는 복지역량을 강화시켜나가야 할 것이다. 마지막으로 지역창조와 재생을 통해 관련 인프라를 확충하여 국토의 고른 공간 창출을 진흥시켜 나가야 할 것이다. Despite local government efforts for regional change, the local self-government based development is vulnerable to deepening disparities between regions. While confronting the paradigm of the latest changes in national and international development of the region that Park Geun-hye government faces, the purpose of this study is to present concrete plans for achieving self-sustaining regional development based on decentralization and balanced development. To this end, with the demands and needs of the times, “The Self-Supporting Development Model of the Regional Circulation” is proposed which professes national unification and balanced regional development as a new regional development paradigm which is based on the creative economy utilizing the local dimension. Ultimately, this is for integrating a domestic and foreign paradigm shift as a systematic theoretical framework and practically applying that in the field. It intends to accomplish this by educating people in the area, making them live in the area, and gathering people into the area. In order to achieve it, we proposed a virtuous and self-supporting development model. Firstly, for tile self-supporting development of the regional circulation, the 3C strategy-Competency, Cooperation, Convergence, Convergence-is proposed. Secondly, in order to achieve self-supporting development as a strategy for promoting regional circulation, we proposed promotion of regional education, regional industrial development, local cultural arts, and community welfare for the creation and regeneration of the region. The first strategy is through promotion of local education by fostering talented people in the regional area. Secondly, by creating jobs for local industrial development and contributing to the creation of a dynamic region. Thirdly, by empowering the local culture and building up the cultural grounds, through promotion of local art and culture. Fourthly, local social welfare should be promoted through community welfare budgets and appropriate infrastructure in order to strengthen the regional social welfare power. As a result, people will benefit through welfare empowerment. Lastly, enhancing the infrastructure through the creation and expansion in the reproduction of the region. As a result of the effort in making a well-balanced regional development, it is expected a well-balanced space development for the whole country.

부산 신항만지역의 환경친화적 에너지 수급계획 : 신항만지역의 표준기상데이터 작성 A Study on the Standard Weather Data for Busan Newport Area

이선애,김용경,이정재,조용수,도근영 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1

Reclamation area has a characteristic nature surroundings than a town-region or a inland area. It has a adverse conditions; low temperature, gale, much sunshine, moistured salt; at climate than inland area. In case propelling development with examining enough topography and climate characteristics of Water Front, climatic environment would grow worth. And it would lead to a rise of energy and maintenance expenses by calculating inaccurate capacity of installed equipments and by occurrence of defects of equipments. On this study, final object is selecting a friendly environment facility system and establishing a accurate energy supply and demand program in grasp of climate characteristic on reclaiming and developing in Busan Newport Area. So we drew up it based on AWS(Automatic Weather System) measure data and standard climate data in Busan Newport Area.

중량저항운동이 중년 여성의 면역글로블린에 미치는 영향

이배익,박영수,권만근 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.2

The purpose of this study was to investigate the effect of 12weeks' resistance training on Immunoglobulin in middle aged women. The subjects of this study employed 20 healthy middle aged women in Pu-san city. The study was conducted two (control group, experimental group) by two (pre-test, post-test) factorial design with data analyzed using ANCOVA. The result of this study was not significantly different in IgA, IgD, IgE, IgG, IgM between control group and training group. Therefore moderate weight traning was not change in Immunoglobulin. the following study is profoundly considerated not only immunoglobulin but also mitogen

우리나라 신부화의 연대별 변천에 관한 연구

이원영,조근호,박천호 한국화훼연구회 2001 화훼연구 Vol.9 No.1

This study focuses on changes in the kinds of flowers, colors, shapes of bridal bouquet in Korea for 50 years from 1950's to 1990's. The results show that two to three kinds of flowers were used in 1960's and 1970's, but various materials were used in 1980's and 1990's. White chrysanthemums rank first in 1950's and 1960's, carnations in 1970's, but roses and cymbidiums in 1980's, and use of cymbidiums, roses, and denphalae increased in 1990's. When it comes to foliage, camellia leaf used most frequently until 1960's and Asparagus in 1970's, but use of various tropical foliage such as scindapsu, ivy, Rumora fern increased in 1980's. In colors, white was most preferred in 1950's and 1960'sl pink was added in 1970's, but both white and pink were used in bouquet and boutonniere in 1990's. In shape, large arm bouquet was most preferred in 1950's. Round bridal bouquet with long asparagus stem was most favorite style in 1960's and 1970's, cascade shape and empire bouquet in 1980's, and various bridal bouquet such as cascade, round, triangular and free style in 1990's. In boutonniere they used triangular most frequently.

열공성 뇌경색과 뇌내출혈의 위험인자 비교

이장준,이현아,최종환,이형,임정근,이상도,박영춘 계명대학교 의과학연구소 2000 계명의대학술지 Vol.19 No.2

Cerebral small vessel disease is the most important cause of lacunar infarction (LI) and intracerebral hemorrhage (ICH). It is generally postulated that, in its early stages, the vascular lesion engenders vessel wall fragility and ICH. But if rupture dose not occur, segmental vessel occlusion evolves, producing LI. It may be a common aging phenomenon that is exacerbated by hypertension and diabetes mellitus. This study was performed to evaluate risk factors of LI and ICH. We reviewed retrospectively the medical records of 690 patients (254 LI, 436 ICH) with stroke who were admitted to Keimyung University Dongsan Medical Center from January 1995 to December 1998. The major risk factors including age, sex, hypertension, diabetes mellitus and several minor risk factors were analyzed in these patients. Older age (p<0.01), male sex(p<0.01), hypertension with treatment(p<0.01), hypertension with long duration(p<0.01) and hypertriglyceridemia(p<0.01), cigarette smoking(p<0.01) were significantly more frequent in LI. Younger age(p<0.01), female sex(p<0.01) and hypertension without treatment(p<0.01), hypertension with short duration(p<0.01) were more frequent in ICH. The prevalence, duration and treatment of diabetes mellitus were not different between these two groups. This study show that the age, sex, treatment of hypertension, duration of hypertension and cigarette smoking seem to be significant risk factors between LI and ICH.

X-선관 지지장치의 형태에 따른 광조사야와 X-선 조사야 차이가 영상의 왜곡에 미치는 영향에 관한 연구

이성길,김영근 광주보건대학 1993 論文集 Vol.18 No.-

The centering error and the difference of X-ray and light field are investigated to the effect of image distortion with X-ray equipment at the hospitals and clinics in Kwang ju. The conclusion is that: 1. The centering error of standing type is investigated more highly than the ceiling type. (p<0.05) 2. The error of centering beam is induced the distortion of image in the skull lateral projection. 3. The regular calibration in X-lay equipment is absolutely necessary for image quality control.

내측 측두엽 간질에서 간질발작 중 언어증상

이장준,이승환,이형,김지언,임정근,손은익,이상도,박영춘 계명대학교 의과학연구소 2000 계명의대학술지 Vol.19 No.1

Background and Objectives : Several speech manifestation are observed in temporal lobe epilepsy(TLE). We studied the frequency of ictal speech manifestations and their localizing and lateralizing value in TLE. Methods : We reviewed 379 seizures recorded on videotape in 135 patients who underwent temporal lobectomy for intractable TLE. We divided patients into group A(n=75) who became seizures free after surgery, and group B(n=60) who were only slightly benefited or unchanged after surgery. Speech manifestations were classified as normal speech, vocalization, or abnormal speech. Abnormal speech was subdivided into speech arrest, dysarthria, dysphasia, or nonidentifiable speech. Results : Speech manifestations occurred in 70(18.5%) seizures of 28 patients. Forty eight seizures of 20 patients were observed in group A, and 22 seizures of 8 patients were observed in group B. In group A, 25 seizures of 11 patients were originating from dominant hemisphere, 23 seizures of 9 patients from nondominant hemisphere. In group B, 13 seizures of 5 patients were originating from dominant hemisphere, and 9 seizures in Lt. side and 6 seizures in Rt. side, respectively) of group A(P>0.05), and eleven seizures of 4 patients(8 seizures from Lt. side and 3 seizure from Rt. side) in group B(P>0.05). Normal speech was observed only seizures from Rt. side in both groups(3 seizures in 1 patient, each group). Dysphasia occurred only in seizures originating from Lt. side. Nonidentifiable speech occurred in 22 seizures of 9 patients(11 seizures from each side) in group A(P<0.01), and 3 seizures of 1 patient occurred only from Lt. side in group B. Conclusion : Ictal speech manifestations were not uncommon(18.5%). All kinds of ictal speech manifestations except normal speech have no reliable lateralizing and localizing value in TLE. Normal speech could be a good indicator of seizure originating from nondominant hemisphere.

기어의 缺陷診斷에 關한 硏究

이재응,유근희,한재영,장흥석 중앙대학교 기술과학연구소 1997 기술과학연구소 논문집 Vol.27 No.-

본 논문에서는 기어의 결함을 진단하는데 있어 다양한 신호처리방법에 의한 결함추적방법에 대해 연구하였으며 이를 실험 결과와 비교함으로서 그 방법들의 타당성을 검증하였다. 시간영역에서는 Time Synchronous Averaging을 이용한 방법, Kurtosis를 이용한 방법, Demodulation을 이용한 방법을 사용하였으며 주파수영역에서는 스펙트럼에 의한 결함진단방법, 켑스트럼을 이용한 결함진당방법, 그리고 시간-주파수영역에서는 Moving Window 에 기초한 STFT(Short Time Fourier Transformation)에 의한 방법, Wavelet Transform에 의한 방법 등을 사용하였다. 각각의 방법마다 결함을 추적하는데 있어 정도의 차이를 보여왔지만 대부분이 결함을 진단할 수 있는 방법임이 증명되었다. 각각의 방법들은 장단점과 한계를 가지고 있으므로 이를 비교하였으며 이 결과를 토대로 측정대상과 측정목적에 따라 각각의 진단방법을 선택할 수 있게 하였다. 기어의 결함을 추적하는데 있어 전달오차가 존재하거나 복잡한 구조물에서는 이러한 진단방법들을 다중적으로 사용함으로서 각각의 장점을 살리며 단점을 보완하는 최적의 진단방법을 구축할 수 있을 것이라 사료된다. In this thesis, the problems of the fault detection of gears are considered, and the several methods are applied to evaluate the performance of detecting the incipient gear damage with real experimental data. A typical gear fault(wear) is intentionally introduced on a gear and the signals are compared with those obtained from the unfault reference gear. The acceleration and the noise signal are measured, and analyzed by time synchronous averaging, demodulation, kurtosis in the time domain, frequency analysis, cepstrum analysis, the short-time moving window, and wavelet transform method in the time-frequency domain. The results show that each method have their own advantages/disadvantages, and therefore it is recommended to use several methods in the field applications.