Phosphorus Removal in Pilot Plant Using Biofilm Filter Process from Farm Wastewater

Shin, Sung-Euy,Choi, Du-Bok,Lee, Choon-Boem,Cha, Wol-Suk The Korean Society for Biotechnology and Bioengine 2006 Biotechnology and Bioprocess Engineering Vol.11 No.4

Various environmental conditions affecting total phosphorus removal from farm wastewater in a biofilm filter process were investigated using loess balls and Chromobacterium LEE-38 at a pilot plant. When Chromobacterium LEE-38 was used, the removal efficiency of total phosphorous was approximately 10- or 5-fold higher than that of Acinetobacter CHA-2-14 or Acinetobacter CHA-4-5, respectively. When a loess ball of $11{\sim}14mm$ manufactured at a $960^{\circ}C$ calcining temperature was used, the removal efficiency of total phosphorous was 90.0%. When 70% of the volume fraction was used, the maximum efficiency of total phosphorus removal was 93.1%. Notably, when the initial pH was in the range of 6.0 to 8.0, the maximum removal efficiency of total phosphorus was obtained after 30 days. When the operating temperature was in the range of 30 to $55^{\circ}C$, the maximum removal efficiencies of total phosphorus, 95.6 to 94.6%, were obtained. On the other hand, at operating temperatures below $20^{\circ}C$ or above $40^{\circ}C$, the removal efficiency of total phosphorous decreased. Among the various processes, biofilm filter process A gave the highest removal efficiency of 96.4%. Pilot tests of total phosphorus removal using farm wastewater from the biofilm filter process A were carried out for 60 days under optimal conditions. When Acinetobacter sp. Lee-11 was used, the average removal efficiency in the p-adsorption area was only 32.5%, and the removal efficiencies of chemical oxygen demand (COD) and biological oxygen demand (BOD) were 56.7 and 62.5%, respectively. On the other hand, when Chromobacterium LEE-38 was used, the average removal efficiency was 95.1%, and the removal efficiencies of COD and BOD were 91.3 and 93.2%, respectively.

A Case of Hobnail Hemangioma

(Shin Taek Oh),(In Gang Jang),(Sung Wook Kim),(Baik Kee Cho),(Seung Dong Lee) 대한피부과학회 2002 Annals of Dermatology Vol.14 No.1

N/A Hobnail hemangioma(HH)is a benign acquired vascular tumor of endothelial origin which should be differentiated from other malignant vascular neoplasm such as Kaposi`s sarcoma or angiosarcoma.We report a case of hobnail hemangioma in a 21-year-old woman who had a dusky-red patch on her left shin.Histologically,ectatic vascular channels with a single layer of plumped endothelial cells were seen and the vascular channels seemed to dissect the collagen bundles.She underwent treatment with surgical excision with primary closure. (Ann Dermatol 14(1)45-47, 2002).

A Multi-Center Educational Research Regarding Breastfeeding for Pediatrics Residents in Korea

Yong Sung Choi,정성훈,김은선,Eun Sun Kim,Eunhee Lee,Euiseok Jung,So-Yeon Lee,이우령,Hye Sun Yoon,Yong Joo Kim,Ji Kyoung Park,Son Moon Shin,Ellen Ai-Rhan Kim 대한신생아학회 2022 Neonatal medicine Vol.29 No.1

Purpose: Pediatricians have a significant responsibility to educate mothers about the importance of breastfeeding. However, there have been minimal efforts in the courses of resident training in Korea. The purpose of this study is to evaluate the change in knowledge and attitude before and after a 4-week breastfeeding educational intervention among multicenter residents. Methods: Prospective interventional educational research was designed for residents at eight training hospitals in Korea. Institutional reviews were obtained in each hospital. The education curriculum consisted of 14 courses regarding breastfeeding theory and practice. These materials were used to teach pediatric residents for 4 weeks. Knowledge-based tests were administered before the course, and re-tests were administered after the course using different test items of similar levels. Test scores and survey responses were compared before and after the intervention. Results: A total of 73 residents (1st year 20, 2nd year 23, 3rd year 16, and 4th year residents 14) from eight training hospitals completed the intervention. Their average age was 30.3±2.9 years, 17 (23.3%) were male, 22 (30.1%) were married, and eight had more than one child of their own. The mean pre-test score was 61.8±13.4 and the mean post-test score was 78.3±7.5 (P<0.001). The inter-grade difference in the score was significant in the pre-test (P=0.005), but not significant in the post-test (P=0.155). There were more responses of obtaining confidence after the intervention (P<0.001). Conclusion: In our study, pediatric residents showed improvement in their knowledge and confidence level after 4 weeks of the breastfeeding curriculum. This will provide a basis for future policymaking in the training of pediatric residents regarding breastfeedReceived: 6 January 2022 Revised: 15 February 2022 Accepted: 15 February 2022 Correspondence to: Ellen Ai-Rhan Kim, MD Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea Tel: +82-2-3010-3390 Fax: +82-2-3010-6978 E-mail: arkim@amc.seoul.kr A Multi-Center Educational Research Regarding Breastfeeding for Pediatrics Residents in Korea Yong-Sung Choi, MD,PhD1, Sung-Hoon Chung, MD, PhD2, Eun Sun Kim, MD, PhD3, Eun Hee Lee, MD4, Euiseok Jung, MD5, So Yeon Lee, MD, PhD5, Wooryoung Lee, MD6, Hye Sun Yoon, MD, PhD7, Yong Joo Kim, MD, PhD8, Ji Kyoung Park, MD, PhD9, Son Moon Shin, MD, PhD9, and Ellen Ai-Rhan Kim, MD, PhD5 1Department of Pediatrics, Kyung Hee University Hospital, Seoul, Korea 2Department of Pediatrics, Kyung Hee University Hospital at Gangdong, Seoul, Korea 3Department of Pediatrics, Kangwon National University Hospital, Chuncheon, Korea 4Department of Pediatrics, Korea University Anam Hospital, Seoul, Korea 5Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea 6Department of Pediatrics, Soonchunhyang University Seoul Hospital, Seoul, Korea 7Department of Pediatrics, Nowon Eulji Medical Center, Eulji University, Seoul, Korea 8Department of Pediatrics, Hanyang University Seoul Hospital, Seoul, Korea 9Department of Pediatrics, Inje University Busan Paik Hospital, Busan, Korea Neonatal Med 2022 February;29(1):28-35 https://doi.org/10.5385/nm.2022.29.1.28 pISSN 2287-9412 . eISSN 2287-9803 Copyright(c) 2022 By Korean Society of Neonatology This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/4.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Original Article 29 Neonatal Med 2022 February;29(1):28-35 https://doi.org/10.5385/nm.2022.29.1.28 ing in Korea.

A Case of Hobnail Hemangioma

Oh, Shin Taek,Lee, Seung Dong,Kim, Sung Wook,Jang, In Gang,Cho, Baik Kee Korean Dermatological Association 2002 Annals of Dermatology Vol.14 No.1

Phosphorus Removal in Pilot Plant Using Biofilm Filter Process from Farm Wastewater

차월석,Sung-Euy Shin,DuBok Choi,Choon-Boem Lee 한국생물공학회 2006 Biotechnology and Bioprocess Engineering Vol.11 No.4

Various environmental conditions affecting total phosphorus removal from farm wastewater in a biofilm filter process were investigated using loess balls and Chromobacterium LEE-38 at a pilot plant. When Chromobacterium LEE-38 was used, the removal efficiency of total phosphorous was approximately 10- or 5-fold higher than that of Acinetobacter CHA-2-14 or Acinetobacter CHA-4-5, respectively. When a loess ball of 11~14 mm manufactured at a 960°C calcining temperature was used, the removal efficiency of total phosphorous was 90.0%. When 70% of the volume fraction was used, the maximum efficiency of total phosphorus removal was 93.1%. Notably, when the initial pH was in the range of 6.0 to 8.0, the maximum removal efficiency of total phosphorus was obtained after 30 days. When the operating temperature was in the range of 30 to 55°C, the maximum removal efficiencies of total phosphorus, 95.6 to 94.6%, were obtained. On the other hand, at operating temperatures below 20°C or above 40°C, the removal efficiency of total phosphorous decreased. Among the various processes, biofilm filter process A gave the highest removal efficiency of 96.4%. Pilot tests of total phosphorus removal using farm wastewater from the biofilm filter process A were carried out for 60 days under optimal conditions. When Acinetobacter sp. Lee-11 was used, the average removal efficiency in the p-adsorption area was only 32.5%, and the removal efficiencies of chemical oxygen demand (COD) and biological oxygen demand (BOD) were 56.7 and 62.5%, respectively. On the other hand, when Chromobacterium LEE-38 was used, the average removal efficiency was 95.1%, and the removal efficiencies of COD and BOD were 91.3 and 93.2%, respectively.

절사표본에서 최적 절사점에 관한 연구

이상은,조민지,신기일,Lee, Sang Eun,Cho, Min Ji,Shin, Key-Il 한국통계학회 2014 응용통계연구 Vol.27 No.3

상당수의 사업체 조사는 절사표본설계법을 사용하고 있다. 이는 절사표본설계법에서 얻은 전수층이 많은 정보를 포함하고 있어 전체 표본크기를 최소화 할 수 있는 장점이 있기 때문이다. 그러나 최근 전수층에 포함된 사업체들의 무응답률이 높아감에 따라 전수층이 가지고 있는 장점에 한계가 나타나고 있다. 이에 Lee (2011), Shin과 Lee (2013)는 표본설계 단계에서부터 주어진 허용오차를 만족하면서 전수층 규모를 최소화하는 연구를 실시하였다. 본 연구에서는 주어진 허용오차를 만족하고 Hidiroglou (1986)가 제안한 방법으로 산출 된 표본크기를 고정한 상태에서 표본층 분산에 알려진 함수를 적합하여 전수층 크기를 최소화하는 새로운 최적 절사점을 제안하였다. 또한 Hidiroglou (1986)와 Shin과 Lee (2013)가 제안한 절단분포를 이용한 방법과 본 연구에서 제안한 방법을 모의실험과 사례연구를 통해 비교하였다. Modified cut-off sampling is widely used for highly skewed data. A serious drawback of modified cut-off sampling is the difficulty of adjustment of non-response in take-all stratum. Therefore, solutions of the problems of non-response in take-all stratum have been studied in various ways such as substitute of samples, imputation or re-weight method. In this paper, a new cut-off point based on minimizing MSE being used in exponential and power functions is suggested and it can be reduced the number of take-all stratum. We also investigate another cut-off point determination method with underlying distributions such as truncated log-normal and truncated gamma distributions. Finally we suggest the optimal cut-off point which has a minimum of take-all stratum size among suggested methods. Simulation studies are performed and Labor Survey data and simulated data are used for the case study.

단순다각형의 최단 외부가시선분을 구하는 최적 알고리즘

이승용(Seung-Yong Lee),신성용(Sung Yong Shin),좌경룡(Kyung-Yong Chwa) 한국정보과학회 1991 한국정보과학회 학술발표논문집 Vol.18 No.1

다각형 P의 내부를 지나지 않는 선분 L로 부터 P의 경계가 모두 보이면 L을 P의 외부가시선분이라 한다. Shin은 정점이 n개인 다각형 P가 주어졌을 때 P의 외부가시선분이 존재하는 가를 조사하고 존재할 경우 외부가시선분을 구하는 O(nlogn) 시간 알고리즘을 제시하였고 Bhattacharya 등은 다각형의 sector 가시성을 이용하여 같은 문제가 O(n) 시간에 해결됨을 보였다. Bhattacharya와 Toussaint은 주어진 다각형이 정점이 n개인 볼록다각형일 때 최단 외부가시선분을 구하는 O(n) 시간 알고리즘을 제시하였다. 본 논문에서는 정점이 n개인 단순다각형 P가 주어졌을 때 P의 최단 외부가시선분을 구하는 O(n) 시간 알고리즘을 제시한다.

Novel Methylation Biomarker for Non-invasive Diagnostics in Lung Cancer

오태정,( Chang Hun Lee2 ),( Min Ki Lee ),( Yeul Hong Kim ),( Sang Yull Lee ),( Hyo Sung Jeon ),( Shin Yup Lee ),( Seung Soo Yoo ),( Jae Yong Park ),( Sung Whan An ) 대한결핵 및 호흡기학회 2012 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.114 No.-

To identify aberrantly hypermethylated DNA in lung cancer cells we established a genome-wide analysis for hypermethylation sites, namely Methyl DNA Isolation and Amplification (MeDIA) coupled-CpG microarray analysis. In the comprehensive methyaltion profiling analysis between human lung cancer, A549 cells and normal NHBE cells, we observed that several clusters of genes show a significant level of aberrancy in CpG island methylation pattern in cancer cells compared to normal cells. We further identified PCDHGA12 gene as a new marker of non-invasive diagnostics for lung cancer based on followings. 1) Transcription of PCDHGA12 gene is reactivated after treatment of A549 cells with demethylating agent. 2) Bisulfide clonal-sequencing reveals that CpG island of PCDHGA12 shows a distinctive differential methylation between two cell lines. 3) Pyrosequencing-based quantitative methylation assay for such region in tumor and non-tumorous tissues from lung cancer patients shows aberrant hypermethylation in 37 (92%) of the 40 tumor tissues. In clinical validation by pyrosequencingin induced-sputum of lung cancer patients (n=87) and healthy controls (n=51), we observed aberrant hypermethylation incident at significantly elevated level in samples derived from lung cancer patients. According to the optimal threshold calculated by ROC curve analysis, sensitivity and specificity of PCDHGA12 was 86.2% and 82.4%, respectively. PCDHGA12 methylation status could be a potential methylation biomarker alone or combined with others for the screen and the detection of relapse of lung cancer.

디스패칭 룰 기반의 시뮬레이션 모델을 활용한 S-PMS 설계

이재용(Jae-yong Lee),김상태(Sang-tae Kim),박선영(Seon-young Park),신문수(Moonsoo Shin1),조용주(Yongju Cho) 한국산업경영시스템학회 2015 한국산업경영시스템학회 학술대회 Vol.2015 No.추계

The up-to-date small and medium-sized enterprises (SMEs) in Korea have tried to respond flexibly and rapidly to dynamic business environment and to establish efficient production management system based on information technologies. However, most of SMEs have faced with low applicability of the production management system resulting from high costs of introduction and maintenance. In this paper, a production planning and control system, that is S-PMS (production management system for SMEs), is proposed to solve the problem of low applicability and limited human resources. S-PMS enables production managers to efficiently collect and manage master data with the actual target production systems and explores the bottleneck process by means of simulation techniques to improve productivity. Furthermore, it implements rescheduling mechanism in terms of a variety of process routes. In essence, intuitive dispatching rules and integrated data management of S-PMS improve field applicability of production management system. Consequently, S-PMS is expected to be used as an efficient production management system of SMEs in Korea.

Effect of Platelet-Rich Fibrin on Repair of Defect in the Articular Disc in Rabbit Temporomandibular Joint by Platelet-Rich Fibrin

( Hyun Su Baek ),( Hye Sung Lee ),( Bok Joo Kim ),( In Kyo Chung ),( Chul Hoon Kim ),( Sun Mi Jin ),( Hie Sung Hwang ),( Sang Hun Shin2 ) 한국조직공학·재생의학회 2011 조직공학과 재생의학 Vol.8 No.6

The objective of this study was to evaluate platelet-rich fibrin (PRF)’s effectiveness in repairing articular disc defect in the temporomandibular joint (TMJ) of rabbits. Eight rabbits were divided into four groups of two rabbits each, corresponding to groups A, B, C, and D. Both TMJs of all of the rabbits were used in the experiments: the right joints comprised the experimental groups, and the left ones, the control groups. The disc defect was circular and 2 mm in diameter. In the experimental groups, the PRF was compressed into the defect, whereas the control group defects were left untreated. A, B, C, and D groups were sacrificed at the 1st, 2nd, 4th and 6th weeks, respectively. The defects of each control group exhibited no specific changes. Contrastingly, in each experimental group, there was an increased number of chondroblasts at the margins of the defects, along with accelerated cell differentiation and a columnar cell arrangement observable at the time of cell differentiation. The experimental groups showed inflammatory cell infiltrations and fibrosis by the 1st week, maturation of chondrocytes by the 2nd week, and proliferation by the 4th week, after which the defects began to be filled with chondrocytes, a process that was complete after the 6th week. In the histological evaluation (H-E), the experimental groups showed significant increases of chondroblasts after the 2nd and 4th weeks, as well as regular columns of chondrocyte arrays observable during cell division. After 6 weeks, the defects were filled with chondrocytes.