http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Hai Le Xuan,Quoc-Dong Hoang,Soon Geul Lee,Dat Pham Xuan,Hoang Tran Viet,Minh Pham Van,Hung Pham Van,Hung Pham Viet,PHAM DUC TUAN,Duc Anh Nguyen 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.2
Ballbots, which have been studied for over ten years, are under-actuated mobile robots that operate using the inverted pendulum paradigm. Controlling a ballbot poses a number of challenges, including maintaining the stable upright posture from the ground in all directions and making sure it follows the desired trajectory. External factors such as a minor change in contact surface properties or fabrication errors can affect the system's stabilization and transfer capabilities. In this study, an adaptive hierarchical sliding mode control algorithm based on an artificial neural network is developed to make the ballbot robust to external factors. The use of the proposed controller ensures system stability despite uncertainties including friction, accidental centrifugal forces and gravity that occur when the ballbot follows the reference trajectory. The system stability is guaranteed on the basis of Lyapunov theory. Control efficiency and robot stability under system uncertainties are demonstrated by numerical simulation.
Huynh Le Thanh Nguyen,Tran Thanh Nhut,Ho Thi Thanh Nguyen,Le Xuan Hoa,Le Viet Hai,Nguyen Thai Hoang 한국탄소학회 2022 Carbon Letters Vol.32 No.6
Enhancing the capacitive deionization performance requires the inner structure expansion of porous activated carbon to facilitate the charge storage and electrolyte penetration. This work aimed to modify the porosity of coconut-shell activated carbon (AC) through CO2 activation at high temperature. The electrochemical performance of CO2-activated AC electrodes was evaluated by cyclic voltammetry, charge/discharge test and electrochemical impedance spectroscopy, which exhibited that AC-800 had the superior performance with the highest capacitance of 112 F/g at the rate of 0.1 A/g and could operate for up to 4000 cycles. Furthermore, in the capacitive deionization, AC-800 showed salt removal of 9.15 mg/g with a high absorption rate of 2.8 mg/g min and Ni(II) removal of 5.32 mg/g with a rate close to 1 mg/g.min. The results promote the potential application of CO2-activated AC for desalination as well as Ni-removal through capacitance deionization (CDI) technology.
Right lumbar lymph trunk injury after right laparoscopic donor nephrectomy: a case report
Le Thanh Dung,Le Nguyen Vu,Than Van Sy,Tran Ha Phuong,Ninh Viet Khai,Dao Xuan Hai,Nguyen Quang Nghia 대한이식학회 2023 Korean Journal of Transplantation Vol.37 No.2
Laparoscopic donor nephrectomy (LDN) is increasingly popular because of its advantages over open surgery. Chyle leak after donor nephrectomy is a rare but potentially lethal complication if not treated appropriately. We describe a case of a 43-year-old female patient with no remarkable history who presented a chyle leak on day 2 after right transperitoneal LDN. Since conservative treatment failed, the patient underwent magnetic resonance imaging (MRI) and intranodal lipiodol lymphangiography, which confirmed the chyle leak from the right lumbar lymph trunk into the right renal fossa. The chyle leak was percutaneously embolized twice, on postoperative day (POD) 5 and POD 10, by a mixture of N-butyl-2-cyanoacrylate and lipiodol. The drainage fluid decreased significantly after the second embolization. The subhepatic drainage tube was withdrawn on POD 14, and the patient was discharged on POD 17. MRI lymphangiography and intranodal lipiodol lymphangiography effectively identified the chyle leak point. Percutaneous embolization seems to be a safe, effective method for treating high-output chyle leaks.
Huan, Le Cong,Tran, Phuong-Thao,Phuong, Cao Viet,Duc, Phan Huy,Anh, Duong Tien,Hai, Pham The,Huong, Le Thi Thu,Thuan, Nguyen Thi,Lee, Hye Jin,Park, Eun Jae,Kang, Jong Soon,Linh, Nguyen Phuong,Hieu, Tr Elsevier 2019 Bioorganic chemistry Vol.92 No.-
<P><B>Abstract</B></P> <P>In search for novel small molecules with antitumor cytotoxicity via activating procaspase-3, we have designed and synthesized three series of novel (E)-<I>N</I>′-benzylidene-4-oxoquinazolin-3(4<I>H</I>)-yl)acetohydrazides (<B>5a-j, 6a-h,</B> and <B>7a-h)</B>. On the phenyl ring ò the benzylidene part, three different substituents, including 2-OH-4-OCH<SUB>3</SUB>, 4-OCH<SUB>3</SUB>, and 4-N(CH<SUB>3</SUB>)<SUB>2</SUB>, were introduced, respectively. Biological evaluation showed that the acetohydrazides in series <B>5a-j</B>, in which the phenyl ring of the benzylidene part was substituted by 2-OH-4-OCH<SUB>3</SUB> substituent, exhibited potent cytotoxicity against three human cancer cell lines (SW620, colon; PC-3, prostate; NCI-H23, lung). Most of the compounds, in this series, especially compounds <B>5c, 5b</B> and <B>5h,</B> also significantly activated caspase-3 activity. Among these, compound <B>5c</B> displayed 1.61-fold more potent than PAC-1 as caspase-3 activator. Cell cycle analysis showed that compounds <B>5b</B>, <B>5c</B>, and <B>5h</B> significantly arrested the cell cycle in G1 phase. Further apoptotic studies also demonstrated compounds <B>5b</B>, <B>5c</B>, and <B>5h</B> as strong apoptotic cell death inducers. The docking simulation studies showed that these compounds could activate procaspase <I>via</I> chelating Zn<SUP>2+</SUP> ion bound to the allosteric site of the zymogen.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Novel (<I>E</I>)-<I>N</I>′-benzylidene-2-(4-oxoquinazolin-<I>3(4H)-yl</I>)acetohydrazides were synthesized. </LI> <LI> The acetohydrazides <B>5a-i</B> exhibited potent cytotoxicity against three human cancer cell lines. </LI> <LI> A number of cytotoxic compounds exhibited good caspase activation activity. </LI> <LI> The cytotoxic compounds were shown to arrest cells at G1 phase. </LI> <LI> The cytotoxic compounds were shown as strong apoptotic inducers. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Outcomes of liver transplantation for hepatocellular carcinoma: Experiences from a Vietnamese center
Khai Viet Ninh,Dang Hai Do,Trung Duc Nguyen,Phuong Ha Tran,Tuan Hoang,Dung Thanh Le,Nghia Quang Nguyen 한국간담췌외과학회 2024 Annals of hepato-biliary-pancreatic surgery Vol.28 No.1
Backgrounds/Aims: Liver transplantation (LT) provides a favorable outcome for patients with hepatocellular carcinoma (HCC) and was launched in Vietnam in 2004. In this study, we evaluated the short-term and long-term outcomes of LT and its risk factors. Methods: This retrospective study analyzed HCC patients who underwent LT at Viet Duc University hospital, Vietnam, from 01/2012–03/2022. The following data were gathered: demographics, virus infection, tumor characteristics, alpha-fetoprotein (AFP) level, Child-Pugh and MELD scores, selection criteria, type of LT, complications, 30-day mortality, and disease-free and overall survival (DFS and OS). Results: Fifty four patients were included, the mean age was 55.39 ± 8.46 years. Nearly 90% had hepatitis B virus-related HCC. The median (interquartile range) AFP level was 16.2 (88.7) ng/mL. The average MELD score was 10.57 ± 5.95; the rate of Child-Pugh A and B were 70.4% and 18.5%, respectively. Nearly 40% of the patients were within Milan criteria, brain-dead donor was 83.3%. Hepatic and portal vein thrombosis occurred in 0% and 1.9%, respectively; hepatic artery thrombosis 1.9%, biliary leakage 5.6%, and postoperative hemorrhage 3.7%. Ninety-day mortality was 5.6%. Five-year DFS and OS were 79.3% and 81.4%, respectively. MELD score and Child- Pugh score were predictive factors for DFS and OS (p < 0.05). In multivariate analysis, Child-Pugh score was the only significant factor (p < 0.05). Conclusions: In Vietnam, LT is an effective therapy for HCC with an acceptable complication rate, mortality rate, and good survival outcomes, and should be further encouraged.
Hoang Vinh Tran,Hai Van Nguyen,Doanh Viet Vu,Thu Dieu Le,Binh Thanh Nguyen,Dang Hai Le 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.2
We report here a simple approach for synthesis of carbon coated magnetite (C@MFe2O4, M=Co, Ni, Fe) with shell@core nanostructured composites that we used as magnetic-nanosorbents for direct yellow (DYG) and moderacid red (RS) as pollutant textile dyes removal via an adsorption process. The synthesized C@MFe2O4 was characterized by TEM, SEM, EDX, XRD, FT-IR and VSM techniques. TEM results indicated that C@MFe2O4 nanocomposites have 20-30 nm of MFe2O4 nanoparticle core and 2-3 nm in thickness of the amorphous carbon shell. The synthesized C@MFe2O4 nanocomposites have the zero point charge (pHZPC) at 5.5, which suggests that DYG and RS, anionic dyes can be adsorbed onto the C@MFe2O4 nanosorbents in the acidic medium. Adsorption of DYG and RS onto magnetic nanosorbents was optimized and adsorption thermodynamic parameters were evaluated, clearly indicating that the adsorption of RS onto synthesized magnetic-nanosorbents was facile more than that DYG. The adsorption isotherm data showed that the adsorption processes of DYG and RS onto Fe3O4 or C@MFe2O4 nanosorbents are more suitable for the Langmuir model than Freundlich model. The maximum adsorption capacity (qmax) of DYG dye onto Fe3O4, C@Fe3O4 and C@CoFe2O4 adsorbents was 14.641, 36.232 and 7.85mg g1, respectively; meanwhile, these values were 41.152, 61.728 and 39.683mg g1 for RS dye. These obtained data indicate that the developed Fe3O4, C@Fe3O4 and C@CoFe2O4 nanoparticles can be used as recoverable and recyclable adsorbents for not only organic pigments adsorption but also for heavy metal ion removal or protein extraction as well.
New Cytotoxic Benzopyrans from the Leaves of Mallotus apelta
Phan Van Kiem,Nguyen Hai Dang,Ha Viet Bao,Hoang Thanh Huong,Chau Van Minh,Le Mai Huong,이정준,김영호 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.10
Two new benzopyrans 6-[1'-oxo-3'(R)-hydroxy-butyl]-5,7-dimethoxy-2,2-dimethyl-2H-1-benzopyran (1) and 6-[1'-oxo-3'(R)-methoxy-butyl]-5,7-dimethoxy-2,2-dimethyl-2H-1-benzopyran (2) were isolated from the leaves of Mallotus apelta Muell.-Arg., (Euphorbiaceae). Their chemical structures were elucidated by spectroscopic analyses, especially by 1D-, 2D-NMR and MS spectra. Compound 1 was found to have strong cytotoxic effect against two human cancer cell lines as human hepatocellular carcinoma (Hep-2, IC50: 0.49 µg/mL) and rhabdosarcoma (RD, IC50: 0.54 µg/mL), while compound 2 showed moderate activity against Hep-2 cell line (IC50, 4.22 µg/mL) by in vitro assay.
New Cytotoxic Benzopyrans from the Leaves of Mallotus apelta
Kiem Phan Van,Dang Nguyen Hai,Bao Ha Viet,Huong Hoang Thanh,Minh Chau Van,Huong Le Mai,Lee Jung Joon,Kim Young Ho The Pharmaceutical Society of Korea 2005 Archives of Pharmacal Research Vol.28 No.10
Two new benzopyrans 6-[1'-oxo-3'(R)-hydroxy-butyl]-5,7 -dimethoxy-2,2-dimethyl-2H-1-ben-zopyran (1) and 6-[1'-oxo-3'(R)-methoxy-butyl]-5,7 -dimethoxy-2,2-dimethyl-2H-1-benzopyran (2) were isolated from the leaves of Mallotus apelta Muell.-Arg., (Euphorbiaceae). Their chemical structures were elucidated by spectroscopic analyses, especially by 1D-, 2D-NMR and MS spectra. Compound 1 was found to have strong cytotoxic effect against two human cancer cell lines as human hepatocellular carcinoma (Hep-2, $IC_{50}\;:\;0.49\;{\mu}g/mL$) and rhabdosarcoma (RD, $IC_{50}\;:\;0.54\;{\mu}g/mL$), while compound 2 showed moderate activity against Hep-2 cell line ($IC_{50}\;:\;4.22\;{\mu}g/mL$) by in vitro assay.
Do, Thi Huyen,Dao, Trong Khoa,Nguyen, Khanh Hoang Viet,Le, Ngoc Giang,Nguyen, Thi Mai Phuong,Le, Tung Lam,Phung, Thu Nguyet,Straalen, Nico M. van,Roelofs, Dick,Truong, Nam Hai Asian Australasian Association of Animal Productio 2018 Animal Bioscience Vol.31 No.5
Objective: In a previous study, analysis of Illumina sequenced metagenomic DNA data of bacteria in Vietnamese goats' rumen showed a high diversity of putative lignocellulolytic genes. In this study, taxonomy speculation of microbial community and lignocellulolytic bacteria population in the rumen was conducted to elucidate a role of bacterial structure for effective degradation of plant materials. Methods: The metagenomic data had been subjected into Basic Local Alignment Search Tool (BLASTX) algorithm and the National Center for Biotechnology Information non-redundant sequence database. Here the BLASTX hits were further processed by the Metagenome Analyzer program to statistically analyze the abundance of taxa. Results: Microbial community in the rumen is defined by dominance of Bacteroidetes compared to Firmicutes. The ratio of Firmicutes versus Bacteroidetes was 0.36:1. An abundance of Synergistetes was uniquely identified in the goat microbiome may be formed by host genotype. With regard to bacterial lignocellulose degraders, the ratio of lignocellulolytic genes affiliated with Firmicutes compared to the genes linked to Bacteroidetes was 0.11:1, in which the genes encoding putative hemicellulases, carbohydrate esterases, polysaccharide lyases originated from Bacteroidetes were 14 to 20 times higher than from Firmicutes. Firmicutes seem to possess more cellulose hydrolysis capacity showing a Firmicutes/Bacteroidetes ratio of 0.35:1. Analysis of lignocellulolytic potential degraders shows that four species belonged to Bacteroidetes phylum, while two species belonged to Firmicutes phylum harbouring at least 12 different catalytic domains for all lignocellulose pretreatment, cellulose, as well as hemicellulose saccharification. Conclusion: Based on these findings, we speculate that increasing the members of Bacteroidetes to keep a low ratio of Firmicutes versus Bacteroidetes in goat rumen has resulted most likely in an increased lignocellulose digestion.