Association between oral health behavior and periodontal disease among Korean adults : The Korea national health and nutrition examination survey

Han, Kyungdo,Park, Jun-Beom Williams & Wilkins Co 2017 Medicine Vol.96 No.7

<P><B>Abstract</B></P><P>This study was performed to assess the association between oral health behavior and periodontal disease using nationally representative data.</P><P>This study involved a cross-sectional analysis and multivariable logistic regression analysis models using the data from the Korean National Health and Nutrition Examination Survey. A community periodontal index greater than or equal to code 3 was used to define periodontal disease.</P><P>Adjusted odds ratios and their 95% confidence intervals of periodontitis for the toothbrushing after lunch group and the toothbrushing before bedtime group were 0.842 (0.758, 0.936) and 0.814 (0.728, 0.911), respectively, after adjustments for age, sex, body mass index, drinking, exercise, education, income, white blood cell count, and metabolic syndrome. Adjusted odds ratios and their 95% confidence intervals of periodontitis for the floss group and the powered toothbrush group after adjustment were 0.678 (0.588, 0.781) and 0.771 (0.610, 0.974), respectively.</P><P>The association between oral health behavior and periodontitis was proven by multiple logistic regression analyses after adjusting for confounding factors among Korean adults. Brushing after lunch and before bedtime as well as the use of floss and a powered toothbrush may be considered independent risk indicators of periodontal disease among Korean adults.</P>

Associations Between the Periodontal Disease in Women Before Menopause and Menstrual Cycle Irregularity : The 2010–2012 Korea National Health and Nutrition Examination Survey

Han, Kyungdo,Ko, Youngkyung,Park, Yong Gyu,Park, Jun-Beom Williams & Wilkins Co 2016 Medicine Vol.95 No.6

<P><B>Abstract</B></P><P>The association between menstrual cycle irregularities and system disease has been evaluated in previous studies. However, the association between periodontal disease and menstrual cycle irregularity has not been fully investigated. The study aimed to evaluate the relationship between periodontal disease and tooth loss in women before menopause and menstrual cycle irregularity using nationally representative data.</P><P>This study performed a cross-sectional analysis and used hierarchical multivariable logistic regression analysis models. Data from Korean National Health and Nutrition Examination Survey (KNHANES) between 2010 and 2012 were analyzed. The analysis in this study was confined to a total of 1553 respondents over 19 years old who had not gone through menopause and had no missing values for the reproductive factors and outcome variables. A community periodontal index was greater than or equal to code 3 was used to define periodontal treatment needs.</P><P>The risk of periodontal treatment needs tended to increase in the presence of menstrual cycle irregularity after adjustment for potential confounders (<I>P</I> for trend in the odds ratios = .0481 in model 1; 0.0613 in model 2; 0.0369 in model 3; 0.0456 in model 4). The number of natural teeth of 28 did not reach statistically significant differences (<I>P</I> for trend in the odds ratios = 0.2204 in model 1; 0.2373 in model 2; 0.2814 in model 3; 0.2609 in model 4).</P><P>Menstrual cycle irregularity was positively associated with the risk of periodontal treatment needs in Korean women before menopause. However, there was no significant association between tooth loss and menstrual cycle irregularity. Menstrual cycle irregularity may be considered to be a potential risk indicator for periodontal treatment needs in Korean women before menopause.</P>

Atopic Disorders and Their Risks of Migraine: A Nationwide Population-Based Cohort Study

Han Ju Hee,Lee Hyun Ji,Yook Hwa Jung,Han Kyungdo,Lee Ji Hyun,박용민 대한천식알레르기학회 2023 Allergy, Asthma & Immunology Research Vol.15 No.1

Purpose: Migraine is a relatively common neurologic disorder. A possible link between atopic disorders and migraine has been suggested. This study investigated atopic disorders and their risks of migraine in the Korean population. Methods: From the Korean National Health Insurance Service database, patients aged ≥ 20 years who underwent health screening between January and December of 2009 were enrolled. To evaluate the risk of migraine, Cox proportional hazards regression analyses were performed. Results: In multivariable analysis, the atopic dermatitis group (adjusted hazard ratio [aHR], 1.28; 95% confidence interval [CI], 1.23–1.33), asthma group (aHR, 1.32; 95% CI, 1.30–1.34) and allergic rhinitis group (aHR, 1.45; 95% CI, 1.44–1.46) had significantly increased risks of migraine compared to their respective control groups (P < 0.001). The patients with 1 (aHR, 1.43; 95% CI, 1.42–1.44), 2 (aHR, 1.50; 95% CI, 1.47–1.53), and 3 (aHR, 1.64; 95% CI, 1.43–1.88) atopic disorders had significantly increased risks of migraine compared to the control group (P < 0.001). Conclusions: Our results demonstrate that patients with atopic disorders may have increased risk of migraine and that the larger the number of concomitant atopic disorders, the higher the risk of migraine.

Association between menopausal hormone therapy and the risk of female gastric cancer: A nationwide population- based cohort study

( Kyung Hee Han ),( Yoon Jin Choi ),( Kyungdo Han ),( Noh Hyun Park ),( Sang Kil Lee ),( Yong Chan Lee ) 대한산부인과학회 2022 대한산부인과학회 학술대회 Vol.108 No.-

Objective: To evaluate the association between menopausal hormone therapy (HT) and the risk of female gastric cancer (GC) Methods: We investigated the national cohort data of women over 40-years old who underwent health checkups by Korean National Health Insurance Service in 2009. After excluding missing data or women previously diagnosed with cancer, final 1,354,621 postmenopausal women were included and divided according to the HT history. We followed study population until 2018, and analyzed the hazard ratio (HR) with 95% confidence intervals (CIs) for the incidence rate of GC in multivariate adjusted model. Results: The number of women with HT history was 214,723 (15.9%) and that of women without HT was 1,139,898 (84.1%). During mean 8.3 years of follow-up periods, a total of 12,496 GC cases developed in the study populations (n=10,962, HT non-users; n=1,534, HT users). In the adjusted model, HT decreased the development of GC by approximately 11% compared to the absence of HT (HR, 0.887; 95% CI, 0.840-0.937). Among HT duration, HT in 2-5 years suppressed GC risk most effectively than no HT (HR, 0.848; 95% CI, 0.762-0.945). Endogenous hormone history such as, age at menarche, parity, and breastfeeding were not associated with the incidence rate of GC. Conclusion: According to our large-scale prospective national cohort study, exogenous HT decreased the GC risk in postmenopausal women. The best period for HT to decrease GC incidence rate was 2-5 years.

Impact of Smoking Behavior Changes on Pneumonia Hospitalization in Smokers with Diabetes Mellitus

( Dong-woo Han ),( Wonyoung Jung ),( Kyu Na Lee ),( Kyungdo Han ),( Sei Won Lee ),( Dong Wook Shin ) 대한결핵 및 호흡기학회 2023 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.136 No.0

The risk of psoriasis in patients with allergic diseases: a nationwide population-based cohort study

( Ju Hee Han ),( Chul Hwan Bang ),( Joon Ho Son ),( Hwa Jung Yook ),( Kyungdo Han ),( Jae Yeon Ryu ),( Jun Young Lee ),( Young Min Park ),( Ji Hyun Lee ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

Background: The spectrum of allergic diseases includes atopic dermatitis (AD), allergic rhinitis (AR), and asthma. To date, the association between allergic diseases and psoriasis has not been evaluated. Objectives: This study was conducted to determine the risk of psoriasis in patients with allergic diseases. Methods: This was a nationwide population-based cohort study in which data of 9,718,722 subjects ≥20 years of age were analyzed. Results: The incidence of psoriasis per 1,000 person-years was 9.57, 3.78, and 4.28 in the AD, AR, and asthma groups, respectively. The AD group exhibited a significantly increased risk of developing psoriasis (hazard ratio [HR], 3.18; 95% confidence interval [95% CI], 3.05-3.31) (P<0.001) after adjustment for confounding factors. The risk of psoriasis was significantly increased in the AR group (HR, 1.32; 95% CI, 1.31-1.34) (P<0.001) and asthma group (HR, 1.30; 95% CI, 1.27-1.33) (P<0.001). The risk of developing psoriasis tended to increase with the number of accompanying allergic diseases. In the presence of all three allergic diseases, the HR of psoriasis was 3.16 (95% CI, 2.70-3.69) (P<0.001). Conclusion: Allergic diseases, particularly AD, may be a risk factor for psoriasis.

여성 방광암 발생 위험 인자로서의 대사 건강 상태에 관한 연구: 우리나라 여성의 국민건강보험공단 국가 건강검진 자료 활용

한다은(Da Eun Han),안순태(Sun Tae Ahn),김종욱(Jong Wook Kim),오미미(Mi Mi Oh),문두건(Du Geon Moon),한경도(Kyungdo Han),박홍석(Hong Seok Park) 대한비뇨기종양학회 2021 대한비뇨기종양학회지 Vol.19 No.4

Purpose: This study investigated metabolic health status as a risk factor for female bladder cancer using the National Health Checkups databases of Korea. Materials and Methods: We defined obesity if body mass index was ≥25 kg/m² and normal weight as <25 kg/m². Metabolic unhealthiness was defined when 3 or more criteria of metabolic syndrome were met. A total of 11,461,618 women who took National health Checkups between 2009 and 2012 were categorized as metabolic healthy normal weight (MHNW), metabolic unhealthy normal weight (MuHNW), metabolic health obese (MHO), and metabolic unhealthy obese (MuHO). Multivariable-adjusted Cox regression was done to analyze the hazard ratio of bladder cancer. Results: The mean age was 48±11.55 years and body mass index was 23.19±2.13 kg/m². During 5.4±1.1 years of follow-up, 3,893 patients were newly diagnosed with bladder cancer. Compared to MHNW group, the hazard ratio of MuHNW group and MuHO group were 1.237 and 1.288, respectively, while 0.997 in the MHO group. As the number of metabolic unhealthy criteria increased, the cumulative incidence of bladder cancer increased. Conclusions: As a result of a large-scale study conducted on the female population in Korea, the risk of bladder cancer increased with metabolic unhealthiness. Even with normal weight, if metabolically unhealthy, the risk of bladder cancer increased. The greater the degree of metabolic unhealthiness, the higher the risk of bladder cancer. Education on metabolic healthiness concerning female bladder cancer is necessary.

Evapotranspiration Estimating in a Rice Field Using Tseb Model with Modified Soil Heat Flux Equation

Kyungdo Lee,Kyunghwa Han,Sukyoung Hong,Kyomoon Shim,Yihyun Kim,Sangil Na 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Triglyceride-Glucose Index Is a Useful Marker for Predicting Future Cardiovascular Disease and Mortality in Young Korean Adults: A Nationwide Population-Based Cohort Study

조윤경,Han Kyungdo,Kim Hwi Seung,정창희,박중열,이우제 한국지질동맥경화학회 2022 지질·동맥경화학회지 Vol.11 No.2

Objective The triglyceride-glucose (TyG) index, the product of fasting triglycerides and glucose, is a useful and cost-effective marker of insulin resistance (IR). Furthermore, the TyG index is a known IR screening tool in healthy young adults but not in those with atherosclerotic cardiovascular disease (CVD). Thus, this study aimed to evaluate the TyG index as a predictor of CVD in healthy young adults. Methods This study enrolled 6,675,424 adults aged 20–39 years without CVD from the National Health Information Database. We categorized them by TyG index quartile from 2009–2017. The study outcomes were stroke, myocardial infarction (MI), and mortality. All outcomes were analyzed by Cox proportional hazards regression analysis while controlling for baseline covariates. Results During a mean 7.4 years of follow-up, 8,506 cases of stroke, 12,312 cases of MI, and 22,667 deaths were recorded. Multivariable-adjusted hazard ratios (HRs) for participants in the highest TyG index quartile demonstrated that they were at higher risk for stroke (HR, 1.253; 95% confidence interval [CI], 1.167–1.346), MI (HR, 1.258; 95% CI, 1.187–1.334), and mortality (HR, 1.151; 95% CI, 1.104–1.200) than those in the lowest TyG index quartile independent of age, sex, smoking, alcohol consumption, physical activity, income, body mass index, blood pressure, and total cholesterol. The HRs for outcomes in the highest quartiles were higher when the TyG index was applied than when triglyceride or fasting glucose alone was applied. Conclusion TyG index, a simple measure reflecting IR, can predict CVD and mortality in young and healthy populations.

Current Trends of Big Data Research Using the Korean National Health Information Database

김미경,Han Kyungdo,이승환 대한당뇨병학회 2022 Diabetes and Metabolism Journal Vol.46 No.4

Recently, medical research using big data has become very popular, and its value has become increasingly recognized. The Korean National Health Information Database (NHID) is representative of big data that combines information obtained from the National Health Insurance Service collected for claims and reimbursement of health care services and results obtained from general health examinations provided to all Korean adults. This database has several strengths and limitations. Given the large size, various laboratory data, and questionnaires obtained from medical check-ups, their longitudinal nature, and long-term accumulation of data since 2002, carefully designed studies may provide valuable information that is difficult to obtain from other forms of research. However, consideration of possible bias and careful interpretation when defining causal relationships is also important because the data were not collected for research purposes. After the NHID became publicly available, research and publications based on this database have increased explosively, especially in the field of diabetes and metabolism. This article reviews the history, structure, and characteristics of the Korean NHID. Recent trends in big data research using this database, commonly used operational diagnosis, and representative studies have been introduced. We expect further progress and expansion of big data research using the Korean NHID.