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Clinical Manifestations and Treatment Outcomes of Eosinophilic Gastroenteritis in Children
Jong Sub Choi,Shin Jie Choi,Kyung Jae Lee,Ahlee Kim,Jung Kyung Yoo,양혜란,문진수,장주영,고재성,강경훈 대한소아소화기영양학회 2015 Pediatric gastroenterology, hepatology & nutrition Vol.18 No.4
Purpose: The aim of the present study was to investigate the clinical features and outcome of eosinophilic gastro-enteritis (EGE) in children.Methods: Our study enrolled 24 children who were diagnosed with EGE from 1993 to 2014 at the Department of Pediatrics, Seoul National University Children’s Hospital. The patients’ clinical manifestations, treatments, and out-comes were reviewed from the medical records.Results: The mean age at diagnosis was 5.3 years. Most patients had gastrointestinal symptoms including diarrhea (54.2%) and abdominal pain (45.8%). Peripheral eosinophilia was present in 91.7% of the patients. Thirteen patients (54.2%) showed anemia, and 15 patients (62.5%) had hypoalbuminemia. EGE was classified as mucosal, sub-serosal, or muscular in 75.0%, 20.8%, and 4.2% of cases, respectively. Three patients showed gastroduodenal ulcers upon endoscopic analysis. A history of allergy was reported in 13 patients, including atopic dermatitis, allergic rhinitis, and asthma. Five patients (20.8%) improved with food restrictions. Among the 19 patients treated with steroids, 11 (57.9%) discontinued steroid treatment without subsequent relapse, 4 (21.1%) relapsed after ceasing steroid treat-ment, and 4 (21.1%) showed no response to steroids. Two patients who were resistant to steroids underwent ther-apeutic surgery. The presence of gastroduodenal ulcers was significantly associated with relapse and steroid resistance.Conclusion: A high suspicion of EGE is warranted when children have nonspecific gastrointestinal symptoms and peripheral eosinophilia. Most patients improved with food restrictions or steroid treatment, although one-third of pa-tients showed a relapse or steroid resistance.
신경섭,박혜원 창원대학교 생활과학연구소 1998 생활과학연구 Vol.- No.2
The purpose of this study is to verify the roles of costume in stage art. As the field of stage arts, folk theatricals, musicals, opers, theastricals and dancings were concernde. In the costume of folk theatricals, exotic tastes and traditional colors of individual conturies are represented. The other hand, the costumes of musical and operas are includings more theatrical informations than folk theatricals. So the characters' types, the situations, the mood of them etc, are transfer to the audience. The imagery is processed in theatricals by the costume. It can be called clothing imagery. In the case of dancings, the movements are very important element. The dancing costume is regarded as a part of dancing performance. Stage arts changing. Te attemts toward the mass of people are increasing. In this circumstances costume design became very important part of stage art. So costume design education is also regarded as a chief part in university level.
김혜진 ( Hye Jin Kim ),윤총원 ( Chung Weon Yun ),도은수 ( Eun Soo Doh ),장준복 ( Jun Pok Chang ),최명석 ( Myung Suk Choi ),양재경 ( Jae Kyung Yang ),박희권 ( Hee Kwon Park ),신학섭 ( Hak Sub Shin ),이서희 ( Seo Hui Lee ),배관호 ( 한국산림과학회 2011 한국산림과학회지 Vol.100 No.4
This study was conducted to describe forest stand characteristics of the habitats of Allium victorialis var. platyphyllum population from the ecological analysis of classification of vegetation types, importance values, species diversity, interspecific association and community similarity in Ulleung Island and Mt. Hambaek, in which investigated by 48 plots (10 m×10 m). The vegetation studied was classified into 1 community group, 2communities, 2 groups and 3 subgroups for a species unit and divided by 5 units for a vegetation unit. In the Fagus engleriana group (vegetation unit 1, 2 and 3), importance value of A. victorialis var. platyphyllum in herb layer showed relatively higher value than other units. Importance value of A. victorialis var. platyphyllum in herb layer had higher value. In the analysis of interspecific association, most of the species associated positively to A. victorialis var. platyphyllum belonged to habitat features of valley area and sub-alpine zone. Therefore, it was considered that the growing environment of A. victorialis var. platyphyllum population was closely correlated to soil moisture and air humidity.
Cavernous Hemangioma of the Abducens Nerve: Clinical Implication of Duplicated Variants: Case Report
Moon, Kyung-Sub,Jung, Shin,Lee, Kyung-Hwa,Lee, Min-Cheol Oxford University Press 2011 Neurosurgery Vol.69 No.3
<B>Abstract</B><B>BACKGROUND AND IMPORTANCE:</B><P>A cavernous hemangioma arising from the abducens nerve has not been previously reported in the literature. Based on the surgical experience with this case, the authors discuss the clinical importance and resectability potential of a duplicated abducens nerve.</P><B>CLINICAL PRESENTATION:</B><P>A 54-year-old woman presented with a recurrence of diplopia that had occurred 3 years before this admission and had spontaneously resolved without any specific treatment. On admission, there were no specific neurological deficits. Magnetic resonance imaging revealed a cone-shaped mass on the right anterior cerebellopontine angle with hemorrhagic change. Surgical resection via a standard right lateral suboccipital approach was performed. A cystic mass was found emerging from the entry zone of the Dorello canal and encircling the larger branch of the duplicate abducens nerve. Because there was no demarcation between the mass and origin branch, both were removed en bloc. Pathology revealed the presence of a cavernous hemangioma mixed with nerve tissue. Despite preserving a small branch of the duplicate abducens nerve, the patient had permanent right abducens palsy.</P><B>CONCLUSION:</B><P>A cavernous hemangioma arising from the abducens nerve should be suspected as a possible diagnosis for a cystic mass on the anterior cerebellopontine angle. Although duplication of the abducens nerve has not been clearly confirmed on clinical grounds, sacrificing the larger branch during surgery may lead to permanent abducens palsy, as in our case.</P>
Moon, Kyung-Sub,Jung, Shin,Seo, Seung-Kwon,Jung, Tae-Young,Kim, In-Young,Ryu, Hyang-Hwa,Jin, Yong-Hao,Jin, Shu-Guang,Jeong, Young-Il,Kim, Kyung-Keun,Kang, Sam-Suk Journal of Neurosurgery Publishing Group 2007 Journal of Neurosurgery Vol.106 No.5
<B>Object</B><P>The authors evaluated the clinical manifestations and surgical results in patients with cystic vestibular schwannoma (VS), and investigated the matrix metalloproteinase (MMP) expression of the cyst fluid and wall in an attempt to elucidate the pathogenesis and characteristics of this disease.</P><B>Methods</B><P>The clinical and neuroimaging features, perioperative findings, and surgical outcomes in 24 cases of cystic VS and 82 cases of solid VS, all of which were treated using the suboccipital approach, were retrospectively compared. To evaluate the role of MMP in cystic VS, gelatin zymography and immunohistochemical studies of the cyst fluid, wall, and solid portion were performed in nine cases of this disease.</P><P>The mean duration of symptoms was shorter (14.0 months compared with 26.1 months; p = 0.04) and the mean size of the tumor was larger (43.8 mm compared with 34.2 mm; p = 0.048) in the cystic than the solid VS group. Although gross-total resection was easier to accomplish in this group (100% compared with 84.1%), adhesion to the facial nerve was more frequent (62.5% compared with 48.8%; p = 0.042). On gelatin zymography studies, MMP-2 expression was ubiquitously observed in all cyst fluids. Immunohistochemical analysis of the cyst wall showed that MMP-2 was apparently localized to the tumor cells on the luminal inner surface, adjacent to the cyst cavity.</P><B>Conclusions</B><P>Resection of cystic VS is complicated by severe adhesion of the tumor capsule to the facial nerve and the large size of the lesion. The authors believe that MMP-2 may be involved in the pathogenesis of cyst formation or in its enlargement and may aggravate adhesion to the facial nerve, either by promoting the enlargement of the tumor or engendering the degradation of the tumor-nerve barrier proteolytically.</P>
You-Sub Kim,Kyung-Sub Moon,Gun-Woo Kim,Sang Chul Lim,Kyung-Hwa Lee,Woo-Youl Jang,Tae-Young Jung,In-Young Kim,Shin Jung 대한뇌종양학회 2015 Brain Tumor Research and Treatment Vol.3 No.2
Background Craniofacial resection (CFR) has been regarded as a standard treatment for various tumors involving the anterior skull base. The purpose of this study was to evaluate the results of CFR for the patients with anterior skull base malignancies in our hospital. Methods We retrospectively analyzed 17 patients with anterior skull base malignancies treated with CFR between 2001 and 2012. Mean follow-up duration was 41 months (range, 2–103 months). Results Intracranial involvement was found in 11 patients (65%) and orbital extension in 6 patients (35%). Classical bifrontal craniotomy was combined with endoscopic endonasal approach in 14 patients and external approach in 3 patients. Vascularized flap was used for reconstruction of the anterior fossa floor in 16 patients (94%). The most common pathological type was squamous cell carcinoma (6 patients). Gross total resection was achieved in all cases. Postoperative complications developed in 4 patients (24%) and included local wound problem and brain abscess. One patient with liver cirrhosis died from unexpected varix bleeding after the operation. Although postoperative treatment, such as radiotherapy or chemotherapy, was performed in 14 patients, local recurrence was seen in 6 patients. The mean overall survival time after the operation was 69.0 months (95% confidence interval: 47.5–90.5 months) with a 1-, 2-, and 5-year survival rate of 82.3%, 76.5%, and 64.7%, respectively. Postoperative radiotherapy was found to be the powerful prognostic factor for favorable survival. Conclusion Considering the higher local control rate and acceptable complication or mortality rate, CFR with adjuvant radiotherapy is a gold standard treatment option for malignant tumors involving anterior skull base, especially with extensive intracranial involvement.