한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

地方公務員의 管理能力開發에 관한 硏究

辛京勳 圓光大學校 1986 論文集 Vol.20 No.1

With the expansion and reinforcement of the administrative function now underway, the quality and competence of government employees is becoming increasingly important. Faced by a rapidly modernizing society, local governments are realizing the urgent need to upgrade the quality and reliability of their administrative service. They know this can be achieved by enhancing the quality and competency of their employees By doing this they can meet the need of residents for a more diverse and higher quality administrative service. Against this backdrop, this study is designed to indentify the problems to the development of the local government employees' managerial competency with special emphasis on their in-service traning. To this end, the study has attempted to evaluate the managerial capacity of local government employees as well as to shed light on the current status of training institutes for local government employees and their attitude toward the in-service training offered by the institutes. The probvlems identified in this study and the recommended measures for their resolution are as follows : 1) The central government needs to pay greater attention to the training of local government employees and offer greater assistance for the more effective implementation of the programs. 2) The educational system should be revised. 3) The working conditions for instructors at those training institutes should be improved. 4) The syllabus of the training programs for middle-ranking officials should be improved. 5) Local government employees should have equal educational opportunity. 6) Local government employees should change their perception and attitude toward in-service training. In conclusion, continued training was found to be essential to the development of local government employees' managerial competency. To prevent the further deterioration of the quality of local government for administrative service, the anthorities concerned should take specific steps to resolve the aforsaid problems, focusing their efforts at first on those problems to which there are obvious, pratical solutions. Greater administrative support offered by the authorities concerned will be crucial to the success of the educational programs. These efforts alone will upgrade the contents and methodology of in-service training for local government employees and thus ensure the development of local administration and the nation as a whole.

地方自治를 위한 住民參與에 관한 硏究

辛京勳 圓光大學校 1991 論文集 Vol.25 No.1

Most serious task in public adm. is how to formulate the direction of the participation chance for citizen in order to problem solving. Citizen participation in public administration has emerged as an important issue since 1970's new public administration. To build up the citizen participation public administration system this thesis has set up the following study objectives; First, to formulate the framework of analysis with reference to the oriented-variables which was forming attitude of citizen participation with the basic of the theoretical backgroung. Second, to analze the present status of citizen participation in Korea. Third, to establish a basis of a new theory for activation of a citizen participation in a face of Local-self autonomy implemention. The method adopted was; First, to establish a existing theory on the citizen participation by a literature study. Second, to study a general problem on the citizen participation by a system approach in a macro levels. In order words, this model was devided into input, conversion, output, and environments dimensions. Third, to analyze citizen's value and behavior by a behavioral approach in a micro levels. So questionaire survey and interview method was mainly conducted. The improtant results of data analysis was follows; First, authorative approach as well as offical approach of citizen participation behavior much weighted in a adminitrative problem-solving. Second, when citizen's opinion was reflected in the public administration and opened administration information to the public, public servants wsa very negative. Third, as a function of citizen participation, the new integration function which gave citizen a identity and belongness was found. Fourth, in a participative consciousness of citizen, this thesis found a regionalism which was concerns about affairs of citizen's dwelling than other places. In conclusion, the author claimed that only when the participation of citizen's in the process of policy-making is institutionized, one can expect that activation of local-autonomy and democratization of public administration. In order to secure social efficiency or democracy, it is desirable the citizen opinions should be reflected in policy-making by institutionizing citizen's participation.

동축이중원관 분류에 있어서의 자연흡인에 관한 연구

신창환,김경훈,이한영 경희대학교 산학협력기술연구원 1997 산학협력기술연구논문집 Vol.3 No.-

The double coaxial pipe jet which consist of a central round air jet(an inner jet) and an annular air jet(an outer jet) have been experimentally investigated. To obtain basic data for an optimum design of the main nozzle for an air-jet loom, we have made measurements of static pressures on the walls of the main nozzle and analyzed flow velocity changes in the nozzle tube by changing air tank pressures and acceleration tube.

Trimethylamine 및 Ranitidine의 N-산화대사능을 이용하여 측정한 FMO 활성도와 FMO3 유전자형의 상관성

이경훈,성송기,차영남,신상구 大韓臨床藥理學會 2000 臨床藥理學會誌 Vol.8 No.1

Chalcone 유도체를 도입한 폴리이미드 배향막에서의 광배향 특성

申東明,鄭敬勳 弘益大學校 科學技術硏究所 2000 科學技術硏究論文集 Vol.11 No.-

The conventional rubbing technique can't satisfy recent demands for alignment quality. Therefore the photoalignment with UV light have been investigated. Polyimide (PI) film was used as an alignment layer, The PI film (4wt%) was spin coated 3) and cured. The thickness of the coated PI film was about 50 nm. By Williamson synthesis 4), the coated PI film was modified with the chalcone derivatives, The LPUV light was irradiated on the PI film. A cell was fabricated by injecting LC (BL001) into a pair of substrate. The LPUV light irradiation caused dimerization between the chalcones or isomerization in the chalcone derivatives. The long alkyl-chains were aligned homeotropically to the PI film. Thereby the alignment direction of LC-molecules was homcotropic to the PI film.

만성신부전 환자에서 Recombinant Human Erythropoietin(rhEPO)의 피하주사시 생체이용율

김경수,이경훈,이영수,김광호,김용식,신상구,박찬웅 大韓臨床藥理學會 1993 臨床藥理學會誌 Vol.1 No.1

행정구역개편에 관한 연구 : 시 ·군통합을 중심으로 Focusing on The Unification of Cities and Counties

신경훈 圓光大學校 1995 論文集 Vol.29 No.1

The contiunous industrialization has brought about the rapid expansion of economic scale and urbanization. Concurrently, the goverment. In this context, administrative efficiency has been and counties to cities. Many problems, however, were found in the separate urban areas from rural areas around focal cities. As a result, the unification of cities and counties were suggested as a necessary policy direction. While assuming that the unification of administrative areas should be oriented to promote administrative efficiency and democracy, this paper discussed the necessity of unifying administrative areas, the possible positive and negative effects of the unification, and the realistic policy alternatives solving potential problems.

대구지방 두부백선에 대한 임상 및 진균학적 관찰

신동훈,김경수,김기홍 대한의진균학회 1998 대한의진균학회지 Vol.3 No.2

Background: The incidence and causative dermatophytes of tinea capitis has been changed with time. Objective: The purpose of this study was to investigate the clinical and mycological features of tinea capitis in Taegu. Methods: We evaluated the clinical and mycologic aspects of tinea capitis in 39 patients registered in Yeungnam University Hospital from January 1981 to June 1998. Results and Conclusion: The incidence of tinea capitis was 1.3% of 3,077 total dermatophytoses. The ratio of male to female patients was 1.6:1. Although most of the patients were children under the age of If, adult patients with tinea capitis were 23.1% of the cases. Frontal scalp was the most frequent site of tinea capitis. The most common causative organism of tinea capitis was Microsporum canis. Trichophyton rubrum and Trichophyton verrucosum were isolated, also.

Stem cell과 Myeloperoxidase가 스티렌, 하이드로퀴논 및 트리클로로에틸렌에 의한 림프구의 자매염색분체 교환과 소핵체 유도에 미치는 영향

이경재,김형아,신민정,성재혁,박정일,한훈,이세훈 대한산업의학회 2001 대한직업환경의학회지 Vol.13 No.3

목적 : 스티렌, 하이드필퀴논 및 트리클로로에틸렌 (TCE)이 사람의 stem cell과 human myeloperoxidase (MPO)에 의해 대사성 활성화되는 지를 규명하고자 스티렌, 하이드로퀴논 및 TCE에 사람의 stem cell 또는 MPO 효소의 첨가가 이들 화학물질에 의한 자매염색분체교환(SCE)과 소핵체 (MN) 빈도에 미치는 영향을 관찰하였다. 방법 : 건강한 남자의 전혈에서 림프루를 분리하여 72시간동안 이중배양하되 배양개시 24시간만에 0.05mM 하이드로퀴논, 1.50 mM 스티렌, 혹은 1.50mM TCE를 전체용량이 30 ㎕가 되도록 아세톤에 희석하여 배양액에 주입하였고 대조군은 아세톤으로 처리하였다. 화학물질 처리 후 즉시 1.3×106 및 2.6×106 cells/ml 농도의 제대혈액으로부터 나온 stem cell 세포액의 상층액이나 1.0 및 2.0 unit의 human myeloperoxidase를 H2O2와 함께 첨가하였다. SCE분석을 위한 배양액에는 배양종료 2.5시간 전에 colchicine을 가한 후 수확하여 Giemsa염색을 하여 metaphase 세포에서 SCE빈도를 분석하였다. MN분석을 위한 배양액에는 배양개시 44시간만에 cytochalasin-B를 가하였고 acridine orange 염색 후 이핵체에서 MN수를 분석하였다. 결과 : 1. stem cell이나 MPO 자체는 SCE나 MN의 빈도에 영향을 미치지 않았다. 2. stem cell이나 MPO는 스티렌에 의해 유도되는 SCE의 빈도를 용량-반응관계로 유의하게 증가시켰고, MN빈도의 경우 step cell이나 MPO에 의해 증가되는 경향이 있었으나 2.0 unit MPO를 첨가한 경우에만 첨가하지 않은 경우에 비하여 유의하게 증가하였다. 3. 하이드로퀴논은 stem cell이나 MPO가 없는 상태에서도 대조군에 비하여 SCE빈도가 대조군에 비하여 높았다. stem cell이나 MPO는 하이드로퀴논에 의한 SCE 빈도를 용량 반응관계로 유의하게 증가시켰지만, MN의 경우에는 증가시키는 경향만 있을 뿐 유의한 차이는 아니었다. 4. TCE자체는 SCE나 MN빈도를 증가시키지 않았다. stem cell은 1.3 ×106 및 2.6 × 106 cells/ml 농도 모두에서 SCE빈도를 유의하게 증가시켰고 MPO는 2.0 unit농도에서만 유의하게 증가시켰다. stem cell이나 MPO모두 TCE에 의한 MN빈도를 증가시키는 경향이 있었으나 유의한 차이는 아니었다. 결론 : 저자들은 스티렌, 하이드로퀴논, 및 트리클로로에틸렌에 의해 유도되는 자매염색분체교환과 소핵체의 빈도가 사람의 stem cell이나 myeloperoxidase에 의해 증가됨을 발견하였으며, 이러한 결과는 myeloperoxidase가 이들 물질의 대사성활성화에 관여함을 암시하고, 또한 아마도 이 물질들의 골수독성과 관련이 있는 것이라고 제시된다. Objectives : The objective of this study was to identify the possible role of stem cell and myeloperoxidase (MPO) in the metabolic activation of styrene, hydroquinone and trichloroethylene, by investigating the effects of stem cell from umbilical cord blood and MPO on the frequency of sister chromatid exchange (SCE) and micronuclei (MN) induction in cultured human peripheral lymphocytes exposed to hese chemicals. Methods : Islated lymphocytes from whole blood were cultured for 72 hours. The cells were treated with 1.50 mM styrene, 50 μM hydroquinone and 1.50 mM trichloroethylene dissolved with acetone (30㎕ in total volume) at 24 hours after the beginning of culture. Control group was treated with acetone only. Immediately after adding these chemicals, 1.3×106 cells/ml and 2.6×106 cells/ml stem cell/ml stained with Giemsa's solution, and acridine orange for sister chromatid exchange, and for micronucleus analysis, respectively. Results : The results were as follows: 1) Myeloperoxidase and stem cell did not significantly affect the frequencies of SCE or MN in the control group. 2) The frequency of SCE or MN with exposure to styrene did not different from control in the absence of stem cell or MPO. Sister chromatid exchange induced by styrene was significantly increased by adding stem cell or MPO in dose-dependent relationship. The frequency of MN induced by styrene significantly increased in the presence of 2.0 unit MPO. 3) The frequency of SCE was significantly increased with exposure to hydroquinone than acetone treated control in the absence of stem cell or MPO. Sister chromatid exchange induction by hydroquinone significantly increased dose-dependently in the presence of stem cell or MPO. There was a tnendency of increase of the MN frequency induced by hydroquinone in the presence of stem cell or MPO, but not significant. 4) It was found that trichloroethylene itself did not increase SCE or MN frequency. Frequency of SCE induced by trichloroethylene was significantly increased with adding stem cell (low and high) and 2.0 unit MPO. Even though them cell or MPO increased the frequency of MN of lymphocyte exposed to trichloroethylene, the difference was not significant. Conclusions : Authors found that the frequencies of both sister chromatid exchange and micronucleus induced by styrene, hydroquinone, and trichloroethylene were increased significantly with the treatment of stem cell or myeloperoxidase. It was suggested that myeloperoxidase may therefore play an important role in the metabolic activation of styrene, hydroquinone, and trichloroethylene and myeloperoxidase probably be involved in the myelotoxicity of these chemicals.