Fascial Free Flap for Reconstruction of the Dorsolateral Hand and Digits: The Advantage of a Thin Contour

Lee, Min Gue,Kim, Jin Soo,Lee, Dong Chul,Roh, Si Young,Lee, Kyung Jin,Choi, Byeong Kyoo Korean Society of Plastic and Reconstructive Surge 2016 Archives of Plastic Surgery Vol.43 No.6

Background Fascial free flaps have been widely used for reconstruction of the hand because they are thin. However, studies reporting objective data regarding the advantages of this approach are lacking. Thus, we report our experience with such flaps. Methods Forty-five cases of fascial free flaps between November 2006 and March 2014 were reviewed. Nine cases involving reconstructed dorsal or lateral defects were included. Four anterolateral thigh fascial free flaps and 5 lateral arm fascial free flaps were examined. Maximal flap contour was assessed by measuring reconstructed tissue thickness at the central area from the surface of the skin to below the bone in a vertical manner using ultrasonography and X-ray data. Contralateral regions were examined in the same manner and a comparative analysis was performed. A questionnaire survey regarding aesthetic satisfaction was also administered. Results All reconstructed parts had a thicker contour than the contralateral side. The average relative percentage of reconstructed tissue thickness was found to be 152% using ultrasonography and 143% using X-ray imaging. According to the aesthetic satisfaction survey, the average rate of satisfaction for patients was 62%, and satisfaction with the flap contour was 72%. Conclusions Using a fascial free flap, the reconstructed tissue was approximately $1.5{\times}$ as thick as the contour of the normal side, which led to positive responses regarding aesthetic satisfaction.

연잎 에탄올 추출물의 항산화 효과

이경석(Kyung-Seok Lee),김민규(Min-Gue Kim),이기영(Ki-Young Lee) 한국식품영양과학회 2006 한국식품영양과학회지 Vol.35 No.2

본 연구에서는 연잎 추출분획물의 항산화 활성을 비교, 검토하고자 하였다. 70% ethanol로 추출한 추출수율은 8.16%였으며 이를 hexane, chloroform, ethyl acetate, butanol, water로 순차 분획한 수율은 butanol층이 36.12%로 가장 높은 수율을 보였으나 대체적으로 극성이 높을수록 높은 분획수율을 나타내었다. 분획물간 총 페놀함량 측정결과 ethyl acetate 분획물의 총 페놀함량이 가장 높게 나왔으며 전자공여능 측정결과 또한 ethyl acetate 분획물에서 가장 우수한 결과를 나타내었다. Ethyl acetate 분획물의 전자공여능은 BHA, BHT와 비교한 결과 BHA와 유사한 결과를 나타내었으며 BHT보다 우수한 값을 나타내었다. 항산화 활성이 높게 나타난 ethyl acetate 분획물을 취하여 TBA가에 의한 지질과산화를 측정한 결과 BHA가 가장 우수한 활성을 보여주었으며 ethyl acetate 분획물은 BHT보다도 활성이 떨어졌으나 이는 ethyl acetate 분획물이 단일물질로 분리정제가 이루어지지 않은 것으로 malonaldehyde 이외 다른 성분이 TBA와 반응하여 발색한 것으로 추측되어졌다. AV와 POV 측정결과 BHA가 가장 우수한 활성을 보여주었으나 ethyl acetate 분획물과 유의적인 차이는 없었으며 BHT에 비해서는 우수한 활성을 나타내었다. This study was investigated on the antioxidative activity of 70% ethanol extracts from lotus (Nelumbo nucifera) leaf. The extraction yields of 70% ethanol extract was 8.16%. The extract was further fractionated subsequently by hexane, chloroform, ethyl acetate, butanol and water. Antioxidative activity was examined by electron donating ability (EDA) using DPPH, TBA value, acid value (AV), and peroxide value (POV), in comparison with commercial antioxidants. Butanol fraction showed the highest extraction yields but ethyl acetate fraction showed the highest phenol content. The ethyl acetate fraction showed the highest EDA. Theantioxidative activity of ethyl acetate fraction determined by AV and POV in accelerated oxidation condition of lard was similar to that of BHA.

병원성 식중독 미생물에 대한 천년초 선인장 추출물의 항균 활성

이경석(Kyung-Seok Lee),김민규(Min-Gue Kim),이기영(Ki-Young Lee) 한국식품영양과학회 2004 한국식품영양과학회지 Vol.33 No.8

본 연구에서는 천년초 손바닥 선인장 유기용매 추출물의 항균성을 비교, 검토하고자 하였다. 70% ethanol로 추출하여 hexan, chloroform, ethyl acetate, buthanol, water로 순차 분획하여 ascorbic acid, benzoic acid와 항균효과를 비교하여 보았다. Escherichia coli 등 Gram positive bacteria 2종, Gram negative bacteria 2종, yeast 1종 등 총 6개의 병원성 식중독 미생물에 대해 항균효과를 검토한 결과 ethyl acetate 분획물이 가장 우수한 항균효과를 나타내었고 이는 동량의 benzoic acid보다 월등히 우수하였다. Gram positive bacteria와 Gram negative bacteria에 대해 유의적 차이가 없는 비슷한 항균효과를 보여주었으나 bacteria에 비해 yeast에서 항균효과는 낮게 나타났다. The 70% ethanol extract from cactus Chounnyouncho (Opuntia humifusa) was fractionated subsequently by hexan, chloroform, ethyl acetate, buthanol and water. The ethyl acetate fraction exhibited strong antimicrobial activities by paper disk diffusion method on the five strains of food born bacteria Bacillus subtilis, Staphylococcus aureus subsp. aureus, Escherichia coli, Salmonella typhimurium and Pseudomonas fluorescens. It has a heat resistance to show inhibitory effect after heat treatment at 110℃ for 1 hr. The ethyl acetate fraction showed almost perfect growth inhibition at over 700 ppm on the tested strains.

한국 소나무류에 잎떨림병을 일으키는 Lophodermium 속 균의 동정

이승규(Seung Gue Lee),이경준(Kyung Joon Lee),나용준(Yong Joon La),양성일(Seong Il Yang),이창근(Chang Keun Yi) 한국산림과학회 1989 한국산림과학회지 Vol.78 No.2

Fallen and living pine needles bearing ascocarps were collected throughout the country from February, 1987 to October, 1988 to identify and describe Lophodermium species associated with Lophodermium needle cast disease of pines in Korea. All of the observed characteristics of given species were compared with published descriptions of the Lophodermium species. As a result of this study, six Lophodermium species were identified and described. L. pinastri was previously recorded while the other five species, i.e., L. australe, L. durzlabrum, L. nitens, L. pini-excelsae and L. pini-pumilae, were unrecorded in Korea. One Lophodermium species has not been fully identified in this study, and tentatively named as L. sp-1. L. australe was observed on the needles of Pinus rigida, P. rigida × taeda and P. taeda, L. pini-excelsae on P. parviflora and P. strobus, L. nitens, L. durilabrum and L. pini-pumilae on P. koraiensis, L. sp-1 on P. thunbergii and L. pinastri on P. densiflora and P. taeda. L. sp-1 was collected from the diseased regions of 2-year-old needles of P. thunbergii and L. durilabrum from P. koraiensis, suggesting pathogenic nature of these fungi.

공통문항 비동등집단 설계에서 다차원 문항반응모형의 연계화와 동등화 결과 비교

정지영(Ji young Jung),이규민(Gue min Lee),강상진(Sang Jin Kang),민경석(Kyung Seok Min) 한국교육평가학회 2016 교육평가연구 Vol.29 No.4

본 연구는 공통문항 비동등집단 설계에서 이차원성을 갖는 검사자료에 다차원 문항반응모형을 적용한 연계화와 동등화 결과를 집단 간 비동등성, 차원 간 상관정도, 검사구조에 따라 모의실험을 통해 비교하였다. 각 연구조건에 따라 모의자료를 생성한 후 Oshima, Davey와 Lee(2000), Li와 Lissitz(2000), Min(2003)이 제안한 MIRT 연계화 방법을 적용하여 연계화를 시행하고 그 결과를 비교하였다. 이후 각 연계화 방법에 따라 공통 척도로 전환 된 모수를 사용하여 Brossman(2010)의 연구에서 제시한 복합 다차원 문항반응이론 관찰점수 동등화, 다차원 문항반응이론의 일차원적 접근 진점수와 관찰점수 동등화방법을 적용하여 동등화 결과를 비교하였다. MIRT 연계화 결과를 보면, Oshima, Davey와 Lee 방법이 Li와 Lissitz, Min 방법에 비해 집단 간 비동등성과 차원 간 상관정도에 따라 연계화 결과가 상대적으로 안정적으로 산출되었고, 검사구조에 따라서는 세 가지 연계화 방법의 결과가 유사하였다. MIRT 등동화 결과를 보면, Oshima, Davey와 Lee 연계화 방법이 적용된 경우에 모든 연구조건에서 세 가지 MIRT 동등화 방법의 결과가 유사하게 산출되었다. 한편 Li와 Lissitz, Min 연계화 방법이 적용된 경우에는 다차원 문항반응이론의 일차원적 접근 관찰점수와 진점수 동등화 방법 간 동등화 결과가 유사하였고, 복합다차원 문항반응이론 관찰점수 동등화 방법은 다른 패턴으로 동등화 결과를 산출하였다. The purpose of this study is to compare the results of MIRT linking and equating according to group nonequivalency, dimensional correlation, and test structures under the common item nonequivalent groups design with two dimensional simulation data. After separate calibration of generated simulation data, estimated parameters were linked by three MIRT linking methods: Oshima, Davey and Lee(2000), Li and Lissitz(2000), and Min(2003). Commonly scaled parameters by each linking method were equated by three MIRT equating methods: full MIRT observed score equating, approximate unidimensionalized MIRT true score, and approximate unidimensionalized MIRT observed score equating developed by Brossman(2010). A summary of the results of this study is divided into two parts because MIRT equating processes include MIRT linking procedures.

리팜핀에 의한 급성 신부전

이동화,박태규,이재성,김희식,김경현,하영준,정성복,도준영,윤경우 영남대학교 의과대학 1998 Yeungnam University Journal of Medicine Vol.15 No.1

Rifampin is common drug to treat tuberculosis. Rifampin induced acute renal failure, hemolytic anemia and thrombocytopenia is rare and severe complication. We have experienced a case of rifampin induced acute renal failure, hemolytic anemia and thrombocytopenia. Forty-six years old male was suffered from reactivation of pulmonary tuberculosis, and had to medicate antituberculosis drugs including rifampin(600mg/day). Seven years age, antituberdulosis medication were successfully administered to treat pulmonary tuberculosis without any side effects of drugs. But eight days after readministration of rifampin. fever, abdominal pain, vomiting, oliguria, elevated BUN and creatinine were developed. And thrombocytopenia was also identified after administration of rifampin. The patient was recovered slowly after discontinuation of rifampin & intensive medical care. The renal function was normalized at 55 days after cessation of rifampin. The renal pathologic findings were interstitial nephritis and acute tubular necrosis. And, the rifampin dependent antibodies were indentified by indirect antiglobulin test in the presence of rifampin. So we report this case with a brief review of literature.

급성 봉소염성 위염 2예

이영호,권영주,이창홍,박영태,최경묵,박명규,표희정 대한소화기내시경학회 1995 Clinical Endoscopy Vol.15 No.1

We had experienced 2 cases of acute phlegmonous gastritis confirmed by endoscopy, microbiological study and surgical pathologic findings. The first was a 61- year-old female who had been diagnosed as the communicating hydrocephalus and the other was a healthy 60-year-old female. Enterococcus fecalis & Klebsiella pneumoniae, Enterococcus fecalis & E.coli were cultured from the gastric tissue and juice obtained by endoscopy in each patient. In both patients, endoscopic findings showed numerous large ulcers and edema with necrotic material and exudate over the whole stomach. Operation findings were markedly edematous and overall ulcerative mucosa in one patient, and hyperemic outlet stricture in the other. Pathologic findings were acute necrotizing inflammation, involving the mucosa and submucosal layer, consistent with acute phlegmonous gastritis. After operation and antibiotics therapy, the patients were rapidly improved. We reported 2 cases of acute phlegmonous gastritis with the review of literature.

ACE Reduces Metabolic Abnormalities in a High-Fat Diet Mouse Model

Lee, Seong-Jong,Han, Jong-Min,Lee, Jin-Seok,Son, Chang-Gue,Im, Hwi-Jin,Jo, Hyun-Kyung,Yoo, Ho-Ryong,Kim, Yoon-Sik,Seol, In-Chan Hindawi Publishing Corporation 2015 Evidence-based Complementary and Alternative Medic Vol.2015 No.-

<P>The medicinal plants <I>Artemisia iwayomogi</I> (<I>A. iwayomogi</I>) and <I>Curcuma longa</I> (<I>C. longa</I>) radix have been used to treat metabolic abnormalities in traditional Korean medicine and traditional Chinese medicine (TKM and TCM). In this study we evaluated the effect of the water extract of a mixture of <I>A. iwayomogi</I> and <I>C. longa</I> (ACE) on high-fat diet-induced metabolic syndrome in a mouse model. Four groups of C57BL/6N male mice (except for the naive group) were fed a high-fat diet freely for 10 weeks. Among these, three groups (except the control group) were administered a high-fat diet supplemented with ACE (100 or 200 mg/kg) or curcumin (50 mg/kg). Body weight, accumulation of adipose tissues in abdomen and size of adipocytes, serum lipid profiles, hepatic steatosis, and oxidative stress markers were analyzed. ACE significantly reduced the body and peritoneal adipose tissue weights, serum lipid profiles (total cholesterol and triglycerides), glucose levels, hepatic lipid accumulation, and oxidative stress markers. ACE normalized lipid synthesis-associated gene expressions (peroxisome proliferator-activated receptor gamma, PPAR<I>γ</I>; fatty acid synthase, FAS; sterol regulatory element-binding transcription factor-1c, SREBP-1c; and peroxisome proliferator-activated receptor alpha, PPAR<I>α</I>). The results from this study suggest that ACE has the pharmaceutical potential reducing the metabolic abnormalities in an animal model.</P>

COMPLEXITY ANALYSIS FOR PRIMAL-DUAL INTERIOR-POINT METHODS FOR SEMIDEFINITE OPTIMIZATION BASED ON A NEW CLASS PROXIMITY FUNCTIONS

Bo Kyung CHOI,Gue Myung LEE 한국산업응용수학회 2011 한국산업응용수학회 학술대회 논문집 Vol.6 No.1

Primal and dual interior-point methods (IPMs) have been well known as the most effective methods for solving wide classes of optimization problems, for example, linear optimization (LO) problem, quadratic optimization problem (QOP), semidefinite optimization (SDO) problem, second-order cone optimization (SOCO) problem and convex optimization problem (CP). The purpose of this paper is to obtain the best known complexity result for a SDO problem. We define a new class of proximity functions for the SDO problem by a new class of kernel functions which are modified by introduced in [12]. Furthermore we formulate an algorithm for our large-update primal-dual interior-point method (IPM) for the SDO by using a new class of proximity functions and give its complexity analysis, and then we show that the best known worst-case iteration bound for our IPMs for the SDO problem.

남성 직장탈 환자의 임상특성, 항문직장생리검사 소견 및 술식의 선택에 대한 고찰

윤서구,이광렬,조경아,황도연,김건욱,강용원,박원갑 대한대장항문학회 2000 Annals of Coloproctolgy Vol.16 No.4