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Wang, Nianfang,Koh, Sungjun,Jeong, Byeong Guk,Lee, Dongkyu,Kim, Whi Dong,Park, Kyoungwon,Nam, Min Ki,Lee, Kangha,Kim, Yewon,Lee, Baek-Hee,Lee, Kangtaek,Bae, Wan Ki,Lee, Doh C IOP 2017 Nanotechnology Vol.28 No.18
<P>We present facile synthesis of bright CdS/CdSe/CdS@SiO<SUB>2</SUB> nanoparticles with 72% of quantum yields (QYs) retaining ca 80% of the original QYs. The main innovative point is the utilization of the highly luminescent CdS/CdSe/CdS seed/spherical quantum well/shell (SQW) as silica coating seeds. The significance of inorganic semiconductor shell passivation and structure design of quantum dots (QDs) for obtaining bright QD@SiO<SUB>2</SUB> is demonstrated by applying silica encapsulation via reverse microemulsion method to three kinds of QDs with different structure: CdSe core and 2 nm CdS shell (CdSe/CdS-thin); CdSe core and 6 nm CdS shell (CdSe/CdS-thick); and CdS core, CdSe intermediate shell and 5 nm CdS outer shell (CdS/CdSe/CdS-SQW). Silica encapsulation inevitably results in lower photoluminescence quantum yield (PL QY) than pristine QDs due to formation of surface defects. However, the retaining ratio of pristine QY is different in the three silica coated samples; for example, CdSe/CdS-thin/SiO<SUB>2</SUB> shows the lowest retaining ratio (36%) while the retaining ratio of pristine PL QY in CdSe/CdS-thick/SiO<SUB>2</SUB> and SQW/SiO<SUB>2</SUB> is over 80% and SQW/SiO<SUB>2</SUB> shows the highest resulting PL QY. Thick outermost CdS shell isolates the excitons from the defects at surface, making PL QY relatively insensitive to silica encapsulation. The bright SiO<SUB>2</SUB>-coated SQW sample shows robustness against harsh conditions, such as acid etching and thermal annealing. The high luminescence and long-term stability highlights the potential of using the SQW/SiO<SUB>2</SUB> nanoparticles in bio-labeling or display applications.</P>
Lee, Junwoo,Lee, Tack Ho,Byranvand, Mahdi Malekshahi,Choi, Kyoungwon,Kim, Hong Il,Park, Sang Ah,Kim, Jin Young,Park, Taiho The Royal Society of Chemistry 2018 Journal of Materials Chemistry A Vol.6 No.14
<P>In this study, we demonstrated the effects of the molecular weight (MW) of a green-solvent processable semiconducting polymer (asy-PBTBDT) on its photovoltaic performance and device thermal stability in green processed devices for the first time. The asy-PBTBDT with a high MW (132 kDa) had the highest <I>μ</I>h values (4.91 × 10<SUP>−3</SUP> cm<SUP>2</SUP> V<SUP>−1</SUP> s<SUP>−1</SUP> without dopants and 5.77 × 10<SUP>−3</SUP> cm<SUP>2</SUP> V<SUP>−1</SUP> s<SUP>−1</SUP> with dopants) as a result of increase in the π-π stacking along with MW as compared to low-MW asy-PBTBDTs (27 and 8 kDa). The high-MW asy-PBTBDT with a high <I>μ</I>h achieved the best power conversion efficiencies of 18.2% and 20.0% for the undoped and doped states in PerSCs, respectively, and 5.7% in PSCs in green processed devices. Furthermore, the glass transition temperature increased with an increase in MW; this indicated an effective decrease in heat-induced morphological degradation in the photovoltaic devices. In addition, an increase in the chain density along with MW led to good robustness against humidity and oxygen.</P>
Comparison Between 18F-Florapronol and 18F-Florbetaben Imaging in Patients With Cognitive Impairment
Kyoungwon Baik,Seun Jeon,Mincheol Park,Young-gun Lee,Phil Hyu Lee,Young H. Sohn,Byoung Seok Ye 대한신경과학회 2023 Journal of Clinical Neurology Vol.19 No.3
Background and Purpose To determine the imaging characteristics and cutoff value of 18F-florapronol (FC119S) quantitative analysis for detecting β-amyloid positivity and Alzheimer’s disease (AD), we compared the findings of FC119S and 18F-florbetaben (FBB) positron- emission tomography (PET) in patients with cognitive impairment. Methods We prospectively enrolled 35 patients with cognitive impairment who underwent FBB-PET, FC119S-PET, and brain magnetic resonance imaging. We measured global and vertex-wise standardized uptake value ratios (SUVRs) using a surface-based method with the cerebellar gray matter as reference. Optimal global FC119S SUVR cutoffs were determined using receiver operating characteristic curves for β-amyloid positivity based on the global FBB SUVR of 1.478 and presence of AD, respectively. We evaluated the global and vertex-wise SUVR correlations between the two tracers. In addition, we performed correlation analysis for global or vertex-wise SUVR of each tracer with the vertex-wise cortical thicknesses. Results The optimal global FC119S SUVR cutoff value was 1.385 both for detecting β-amyloid positivity and for detecting AD. Based on the global SUVR cutoff value of each tracer, 32 (91.4%) patients had concordant β-amyloid positivity. The SUVRs of FC119S and FBB had strong global (r=0.72) and vertex-wise (r>0.7) correlations in the overall cortices, except for the parietal and temporal cortices (0.4<r<0.7). The FC119S SUVR had significant negative vertex-wise correlations with cortical thicknesses in the posterior cingulate, anterior cingulate, parietal, posterior temporal, and occipital cortices. Conclusions Quantitative FC119S-PET analysis provided reliable information for detecting β-amyloid deposition and the presence of AD.
( Kyoungwon Jung ),( Hye-kyung Jung ),( Joong Goo Kwon ),( Chung Hyun Tae ),( Ki Bae Bang ),( Jong Kyu Park ),( Ju Yup Lee ),( Cheol Min Shin ),( Jung Hwan Oh ),( Kyung Ho Song ),( Oh Young Lee ),( My 대한소화기기능성질환·운동학회 2022 Journal of Neurogastroenterology and Motility (JNM Vol.28 No.1
Background/Aims Patient-reported outcomes (PROs) are essential for clinical decision making, conduction of clinical research, and drug application acquisition in functional gastrointestinal disorders. The aim of this study is to develop a PRO instrument and to determine the respondents’ perception of the efficacy of therapeutic agents for functional dyspepsia (FD). Methods A self-evaluation questionnaire for dyspepsia (SEQ-DYSPEPSIA) was developed and validated through a structured process. The 2-week reproducibility was evaluated, and the construct validity was assessed by correlating the scores of SEQ-DYSPEPSIA (including typical and major FD symptom subscales). Finally, the response to medication was assessed by comparing the changes after 4 weeks of treatment. Results A total of 193 Korean patients (age 48.5 ± 13.6 years, 69.4% women) completed the questionnaire. SEQ-DYSPEPSIA with 11 items had a good internal consistency (alpha = 0.770-0.905) and an acceptable test-retest reliability (intraclass correlation coefficient = 0.733-0.859). The self-evaluation questionnaire (SEQ)-major FD score highly correlated with the postprandial fullness/early satiety domain of the Patient Assessment of Gastrointestinal Symptom Severity Index (correlation coefficient r = 0.741, P < 0.001), Nepean Dyspepsia Index-Korean version (NDI-K) (r = 0.839, P < 0.001), and NDI-K quality of life (r = -0.275 to -0.344, P < 0.001). After medical treatment, decrease in the SEQ-typical FD and SEQ-major FD was significantly greater in the responder group than in nonresponder group (P = 0.019 and P = 0.009, respectively). Conclusion This study suggests that the Korean version of SEQ-DYSPEPSIA has good reliability and validity, and can be a useful PRO measurement tool in patients with FD. (J Neurogastroenterol Motil 2022;28:111-120)
Trauma surgery without proper compensation under the current Korean National Health Insurance System
Kyoungwon Jung,Yunjung Heo,John Cook-Jong Lee,Mijin Lee,Suni Son,Hee Suk Park,Joo-Ok Kim,Jeong Hee Lee 대한외과학회 2017 Annals of Surgical Treatment and Research(ASRT) Vol.92 No.5
Purpose: This study aimed to evaluate the situations and problems of the current health insurance fees for trauma surgeries. Methods: We reviewed the medical records and billing data from trauma surgeries performed in the hospital from August 2012 to July 2014. The name and number of surgeries were investigated and the code and number of operations prescribed by surgeons were compared with the number of cases actually billed to insurance. In addition, the results returned by the Health Insurance Review & Assessment Services (HIRA) after deduction were investigated and compared to verify the insurance review findings. Results: During the study period, total 1,534 trauma surgical procedures were performed for a total of 253 trauma patients. Based on names, 1,092 procedures were performed; however, 442 cases (28.8%) could not be prescribed because of lack of proper insurance codes for the procedures. A total of 1,046.5 surgical procedures were prescribed by surgeons, adjusted by the insurance team, and finally billed to the HIRA; 162 bills were returned from the HIRA after rate reductions, corresponding to a reduction rate of 15.5%. The major reason for reduction was “fee criteria and limited number”. The compensation rate for billed surgical procedures was 84.5%. Conclusion: The high reduction and low compensation rate for trauma surgery under the current Korean National Health Insurance System need to be reviewed and improved. Furthermore, it is necessary to establish new criteria for surgical procedures fees for latest ones such as damage control surgery performed on severe trauma patients.
Kim, Kyoungwon,Lee, Deuk-Hee,Lee, Sang Yeol,Jang, Gun-Eik,Kim, Jin-Sang Springer 2012 NANOSCALE RESEARCH LETTERS Vol.7 No.1
<P>Silver and aluminum-co-doped zinc oxide (SAZO) nanowires (NWs) of 1, 3, and 5 at.% were grown on sapphire substrates. Low-temperature photoluminescence (PL) was studied experimentally to investigate the p-type behavior observed by the exciton bound to a neutral acceptor (A<SUP>0</SUP>X). The A<SUP>0</SUP>X was not observed in the 1 at.% SAZO NWs by low-temperature PL because 1 at.% SAZO NWs do not have a Ag-O chemical bonding as confirmed by XPS measurement. The activation energies (<I>E</I><SUB>a</SUB>) of the A<SUP>0</SUP>X were calculated to be about 18.14 and 19.77 meV for 3 and 5 at.% SAZO NWs, respectively, which are lower than the activation energy of single Ag-doped NW which is about 25 meV. These results indicate that Ag/Al co-doping method is a good candidate to make optically p-type ZnO NWs.</P>
Kim, Kyoungwon,Park, Dong-Hoon,Debnath, Pulak Chandra,Lee, Dong-Yun,Kim, Sangsig,Jang, Gun-Eik,Lee, Sang Yeol American Scientific Publishers 2012 Journal of nanoscience and nanotechnology Vol.12 No.4
<P>Using a hot-walled pulsed laser deposition (HW-PLD), nanowires (NWs) comprising 3 weight% Ga-doped ZnO (3GZO) have been successfully grown on a sapphire substrate. The structural and optical properties of 3GZO nanostructures have also been systematically investigated with respect to the target-substrate (T-S) distance and the growth temperature. The morphology transformations of nanostructures such as nano-horns, NWs, and clusters are strongly affected by growth temperatures due to different thermal energy. Also, the morphologies of nanostructures--including length, diameter, and density--are strongly affected by the T-S distance, illustrating a close correlation between the growth kinetics and the position in the plume formed by the particles from the GZO target. Also, the exciton that is bound to the neutral donor (D(0)X) peak of the 3GZO nanostructures is found at the low temperature PL spectra, indicating successful Ga-doping into ZnO NWs.</P>
Hearing Aid Selection: Closed- versus Open-canal Fitting Hearing Aids
Sangyeon Lee,Soo Hee Oh,Kyoungwon Lee 한국청각언어재활학회 2021 Audiology and Speech Research Vol.17 No.4
To select hearing aid is an essential process for successful hearing rehabilitation. The purpose of this study is to review hearing aid selection considerations between receiver in-the-canal (RIC) and custom hearing aid (CHA) in order to guide appropriate selection of the hearing aid. This study discussed three key factors in the hearing aid selection including physical, acoustic and electroacoustic characteristics and other aspects. Advantages of RIC types are comfort to wear, reduction of the occlusion effect, presence of directional microphones, on-site fit, easy onnectivity with other devices, and use of rechargeable batteries. On the other hand, the CHA types have their advantage in terms of being comfort to wear with masks, proper insertion and placement, reduction of the acoustic feedback, good approximation of frequency response curve, improvement of speech in noise perception, expanded hearing aid candidacy with varying hearing thresholds, and easy telephone use. We concluded that appropriate selection of the hearing aid would contribute to
Sensitivity-tuned CO gas sensors with tailored Ga-doping in ZnO nanowires.
Kim, Kyoungwon,Lee, Deuk-Hee,Jeong, Dawoon,Debnath, Pulak Chandra,Lee, Dong-Yun,Kim, Sangsig,Lee, Sang Yeol American Scientific Publishers 2012 Journal of Nanoscience and Nanotechnology Vol.12 No.5
<P>Sensitivity-customization of zinc oxide (ZnO) nanowire (NW) gas sensors has been demonstrated by controlling Ga-doping, thereby tuning the resistance of the NWs. Both un-doped and 5 weight% Ga-doped ZnO (GZO) NWs are synthesized for the highly sensitive sensing within a narrow detection window and a less sensitive one within an expanded window, respectively. We have employed hot-walled pulsed laser deposition (HW-PLD) for the NW synthesis. With CO gas injection, the resistance reduction of NWs is detected and analyzed in a self-designed gas chamber that guarantees the precise control of gas flow and, gas concentration, as well as temperature. NW sensitivity is proportional to the sensing temperature and inversely proportional to the doping concentration resulting in widening the sensing window up to 230 times by the 5 wt.% Ga-doping.</P>