파킨슨씨병에서 Selegiline HCI (MAO-B^(�))의 효과 및 안전성

조기현,김명규,김태선,김병채,이승한,황인용,김준태,김종기 全南大醫大 2000 전남의대학술지 Vol.36 No.2

Enalapril 에 의한 기침 발생율

노승익(Seung Ik Roh),김명선(Myeong Seon Kim),김은실(Eun Sil Kim),서두선(Du Seon Seo),정내인(Nae In Jeong),이명숙(Myeong Suk Lee),한승수(Seung Soo Han),김광희(Kwang Hoi Kim),김윤권(Yoon Kweon Kim) 대한내과학회 1994 대한내과학회지 Vol.47 No.1

N/A Background: Enalapril is an angiotensin-converting enzyme inhibitor that has been widely used in treating hypertension, congestive heart failure, DM and various renal diseases. Cough has been recognized as a side effect of angiotensin-converting enzyme inhibitors. Therefore we studied the incidence and the chracteritics of Enalapril induced cough in Korea. Method: The sixty eight patients with Enalapril who visited out-patients department of internal medicine, Han-Il General Hospital during the period from april 1992 to october 1992 were included in this study. In all patients careful history taking and review of chart was done. Patients with respiratory disease were excluded. The criteria of angiotensin converting enzyme inhibitor induced cough was that cough developed after administration of Enalapril and improved after discontinuing drug and readministration of drug induce resume of symptom. Resnlts: Subjects include 34 males, 34 females and their average age was 53.3 years, Diseases of theirs were hypertension (57 cases}, congestive heart failure (5 eases), various renal disease (28 cases) and 9 patients of them were smokers. Average drug dosage was 11.7 mg a day and average administration duration was 182 days. Of the 68 patients, 23 patients (33.8%) had chronic cough due to enalapril, which had 12 male and 11 female patients. The cough disappearing time after withdrawal of the angiotensin-converting enzyme inhibitors was average 7.8 days. In 16 patients (two thirds of them), cough disappeared within 4 days after drug withdrawal. 9 patients had to stop taking drug because of severe cough. Generally the characters of cough induced by angiotensin-converting enzyme inhibitors were dry, persistent, tickling and tended to develope especially at night, Conclusion: Cough is not uncommon side effect in angiotensin-converting enzyme inhibitor users. There fore clinician should consider angiotensin-converting enzyme inhibitor induced cough initially when cough developed after angiotensin-converting enzyme inhibitor administration.

IBC-2000의 耐震設計 基準

김명한 경운대학교 산업기술연구소 2002 産業技術硏究論文誌 Vol.5 No.1(A)

Seismic design provisions of our country, which were based on the ATC 3-06 and Uniform Building Code of United States, were established first in 1988. From that time on, the provisions have been maintained the initial framework with few revisions. However, the seismic design regulations of United States and other countries have been modified and developed considerably based on the continuous researches and a large number of experiments in 1990's. To improve our national provisions and adopt the recent developments in the field of earthquake engineering, it may be necessary to focus on the International Building Code of International Code Council. IBC is the single model code of United States coordinated from the three separate model codes; Uniform Building Code, National Building Code, and Southern Building Code. In this paper, the principal regulations and their bases of IBC published in 2000 are introduced.

내진구조해석을 위한 시스템 연성비 평가

김명한 경운대학교 산업기술연구소 2002 産業技術硏究論文誌 Vol.5 No.1(A)

Response modification factor is an important coefficient in seismic design to reflect ductility, overstrength, redundancy and damping characteristics of structure. But the theoretical and experimental basis of the factor is quite weak. For the more reasonable evaluation of that factor, ductility ratio has been determined by analyzing inelastic properties of the equivalent SDOF system derived from MDOF system or inelastic static analysis. However, the analysis of equivalent SDOF system is fairly approximate method, and inelastic static analysis cannot reflect the characteristics of real seismic load. The evaluation and comparison of system ductilities using inelastic static analysis and inelastic dynamic analysis were performed in this study. The general-purpose computer program Drain-2DX (ver. 1.10) was used to perform analysis for the example structures. The example structures were 7-story, 15-story and 25-story RC-buildings. El Centro earthquake (NS, 1940) and Taft earthquake (S69E, 1952) records were selected for the inelastic dynamic analysis. The collapse criteria of the structure were based on the performance level suggested in ATC-40. From this comparison study, it was concluded that inelastic dynamic analysis could reflect more exactly the hysteretic characteristics of seismic behaviors and the higher mode effects.

비ST분절상승 급성관동맥 증후군 환자에서 N-terminal Pro B-type Natriuretic Peptide(NT-proBNP)를 이용한 관동맥 협착의 중증도 및 초기 위험도 평가

김기석,한혜숙,황경국,연태진,김동운,조명찬 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

이해를 위한 문장 처리에서 통사 요인과 의미 요인

김영진,조명한 서울대학교 어학연구소 1981 語學硏究 Vol.17 No.1

Studies in sentence comprehension reveal that conflicting views currently exist about the part played by syntax. The autonomy model of syntax processing claims that the operation of syntactic processor is not guided or intervened by an assessment of the plausible semantic relations while the automaticity model views that the crucial properties of sentence to which listeners normally attend are semantic rather than syntactic. The present experiments were carried out to examine the listener's on-line accessibility to the surface structure of sentences, and to find out any possible effects of semantic factors on syntactic processing. The method of click monitoring was adopted and the RT was measured throughout the Experiments I, Ⅱ, Ⅳ and V with the exception of Experiment Ⅲ in which subjects were asked about the semantic relations implied in the stimulus sentence. The on-line measures of RT showed no difference of word-order effects either in the materials of both concrete and abstract sentences (Experiment I and Ⅱ) or between the reversible and nonreversible sentences (Experiment Ⅳ). To be surprisingly enough when compared with the English data, moreover, there was no difference in the syntactic computational difficulty between the subject relatives and the object relatives (Experiment Ⅲ).On the other hand, the sentence containing the left branching relatives (the right branching sentences) were consistently superior to the center-embedded relative sentences, the results being due to the left-to-right syntactic processing. In addition, the word meaning coherence made significantly reduce the monitoring RT in overall levels of syntactic complexity without interaction (Experiment V). The shortened RT without interaction of semantic factor with syntactic structure supports the automaticity claims. However, the fact that difference between the right branching and self-embedded sentences occurred only when there is more than one relative (Experiment Ⅲ) enables one to favor the autonomy model in so far as no additional load is imposed upon the upper-limit of the short-term processing capacity. Accordingly, mental strategies for the Korean language comprehension were proposed, in which the syntactic processing undergoes the left-to right coding procedure and the semantic processing represents the bottom-up procedure.

급성기 피질하부 뇌경색에서 확산강조 자기공명영상과 관류 자기공명영상의 임상적 유용성

이승한,김병채,최성민,김명규,서정진,조기현 全南大醫大 2001 전남의대학술지 Vol.37 No.3

참깨에서 추출한 Sesamin 섭취가 혈청 지질 농도에 미치는 영향

윤명호,신준한,김한수,탁승제,최병일 아주대학교 1997 아주의학 Vol.2 No.2

Objectives : High serum cholesterol is one of the major risk factors of coronary artery disease. We investigated the lipid-towering property and the side effects of sesamin, an unsaturated fatty add extracted from sesame oil, for the primary prevention of coronary artery disease. Methods : The 37 patients (20 mates and 17 females) with hyperlipidemia, ages ranging from 22 years to 70 years old (48±12), who did not have atherosderotic diseases except essential hypertension were given three capsules of sesamin once daily for 6 weeks. The lipid profile of the patients were examined before and after sesamin treatment, and the patients were grouped according to the presence or abscence of hypertension, smoking habit and obesity. Result : Compared with pretreatment, the total cholesterol level of sesamin treated group decreased significantly (254.2±29.6 versus 241.6 34.0 ㎎/dl, p< 0.05). The level of LDL-cholesterol (162.6±24.3 versus 156.6±32.8 ㎎/dl)HDL- cholesterol (47.5±10.0 versus 47.0±8.7 ㎎/dl) and triglyceride (196.5±95.4 versus 179.3±96.7 ㎎/dl) and the ratio of LDL/HDL- cholesterol (3.6±0.9 versus 3.4±0.9) were not significantly different. The effect of cholesterol lowering property of sesamin was predominant in hypertensive, non- smoking and obese group (P< 0.05 vs pretreatment). The laboratory tests including complete blood cell counts, serum transaminases, total protein, albumin, blood urea nitrogen, creatinine and blood glucose did not change significantly. Conclusion : The lipid lowering effect of sesamin was statistically significant on the total cholesterol particularly with obese, non-smoking and hypertensive patients. There was no significant side effect during sesamin administration. Therefore, three capsules of sesamin as a single daily dose were effective in lowering total cholesterol and safe to administer in patients with hyperlipidemia.

데이타베이스 시스템을 이용한 웹 자원 관리 엔진의 설계 및 구현

이명석,김진호,김상욱,유한양 강원대학교 정보통신연구소 1999 정보통신논문지 Vol.3 No.-

In this paper, we propose a web resource management engine based on general DBMSs. The web resources management engine manages the meta information describing the characteristics of resourves in a target web site. The engine extracts the meta information from HTML documents in the site and stores it into a predefined database called virtual schema. We use a general-purpose DBMS for maintaining the virtual schema. For design of the virtual schema, we model each element of HTML documents as a DBMS relation, and each attribute of an element as an attribute of its corresponding DBMS relation. We also model the link information among HTML documents as another relation. In order to merge the web and database having the virtual schema, we employ some additional tags in HTML documents, which were originally proposed in the INFORMIX WebDataBlade. Our web resource management engine has the following good features: (1) it supports dynamic changes of the web resources in a site by issuing update queries on the virtual schema, (2) it provides such searches that are based on structural characteristics of HTML documents since the virtual schema keeps the necessary information, (3) it provides the standard SQL interface for users to simply search and update the web resources, and finally, (4) it is portable to any DBMSs by just extending the gateway between the web and database since it only uses the common facilities supported by general-purpose DBMSs.

관상동맥내 스텐트 시술시 Aspirin과 Cilostazol 2개월 병합요법

윤명호,탁승제,염철훈,장혁재,최소연,유상용,안성균,고종훈,신준한,김한수,최병일 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.8