소고춤 참여가 여성 노인의 뇌 기능에 미치는 영향: 뇌파측정 방법을 중심으로

서연수 ( Seo¸ Yeonsoo ),김운미 ( Kim¸ Un-mi ) 무용역사기록학회 2021 무용역사기록학 Vol.60 No.-

본 연구는 소고춤 학습이 여성 노인의 뇌 기능에 미치는 영향을 규명하고자 한다. 이를 위해 연구 대상은 60세 이상의 여성 노인으로 실습에 참여한 실험집단 15명, 참여하지 않은 통제집단 15명으로 구성하였고, 실습 기간은 12주간 주 2회 60분씩 실시하였다. 각 집단은 실험 전후 뇌파검사 EEG를 통해 뇌 기능분석을 측정하였으며, 자료 처리는 SPSS 25.0(IBM, USA)을 이용하여 집단(소고춤, 통제 군)과 기간(사전, 사후)의 차이를 알아보기 위하여 이원변량 반복측정 분산분석(Two-way ANOVA with repeated measures)을 실시하였다. 모든 통계적 유의수준은 p<.05로 설정하여 실시한 결과 다음과 같은 결론을 얻었다. 첫째, 소고춤 프로그램을 통해 집단에 따른 차이가 나타난 뇌 기능 지수는 기초율 동지수(좌뇌, 우뇌), 주의지수(좌뇌, 우뇌), 활성지수(좌뇌, 우뇌), 정서지수, 항 스트레스지수(좌뇌, 우 뇌) 총 5가지 뇌 기능 지수에서 유의미한 변화가 나타났다. 둘째, 소고춤 프로그램을 통해 기간에 따른 차이가 나타난 뇌 기능 지수는 자기조절 지수, 기초율동 지수(좌뇌), 주의지수(우뇌), 정서지수, 브레인 지수 총 5가지 뇌 기능 지수에서 유의미한 차이가 있는 것으로 나타났다. 이러한 연구 결과는 소고춤의 활용 가치를 통해 한국춤 고유의 특징과 본질적 가치를 과학적으로 입증할 수 있으며, 뇌 과학 기반의 무용연구가 다방면으로 이루어지길 기대한다. This study sought to identify the effects of Sogo dance learning on brain function in elderly women. To this end, the subjects of the study consisted of 15 experimental groups participating in the practice and 15 non-participating control groups, with the practice period of 60 minutes twice a week for 12 weeks. Each group measured brain functional analysis with Electroencephalogram(EEG) before and after the experiment, and two-way ANOVA was conducted to determine the difference between group (small dance, control group) and period (pre-post) using SPSS 25.0 (IBM, USA). All statistical significance levels were p<.The following conclusions were obtained as a result of setting it to 05. First, the brain function index, which varied between the groups, showed significant changes in five brain function indices: basic rate coefficient (left brain, right brain), attention index (left brain, right brain), active index (left brain, right brain). Second, the brain function index, which differed over time showed significant differences in total of five brain function indices: self-regulation index, basic rhythm index (left brain), attention index (right brain), emotional index, and brain index. These findings could scientifically prove the unique characteristics and intrinsic value of Korean dance through the utilization value of Sogo Dance, and it is hoped that brain science-based dance research will take place in many ways

FGF21 induced by carbon monoxide mediates metabolic homeostasis <i>via</i> the PERK/ATF4 pathway

Joe, Yeonsoo,Kim, Sena,Kim, Hyo Jeong,Park, Jeongmin,Chen, Yingqing,Park, Hyeok-Jun,Jekal, Seung-Joo,Ryter, Stefan W.,Kim, Uh Hyun,Chung, Hun Taeg Federation of American Societies for Experimental 2018 The FASEB Journal Vol. No.

<P>The prevalence of metabolic diseases, including type 2 diabetes, obesity, and cardiovascular disease, has rapidly increased, yet the molecular mechanisms underlying the metabolic syndrome, a primary risk factor, remain incompletely understood. The small, gaseous molecule carbon monoxide (CO) has well-known anti-inflammatory, antiproliferative, and antiapoptotic effects in a variety of cellular- and tissue-injury models, whereas its potential effects on the complex pathways of metabolic disease remain unknown. We demonstrate here that CO can alleviate metabolic dysfunction <I>in vivo</I> and <I>in vitro</I>. We show that CO increased the expression and section of the fibroblast growth factor 21 (FGF21) in hepatocytes and liver. CO-stimulated PERK activation and enhanced the levels of FGF21 <I>via</I> the eIF2α–ATF4 signaling pathway. The induction of FGF21 by CO attenuated endoreticulum stress- or diet-induced, obesity-dependent hepatic steatosis. Moreover, CO inhalation lowered blood glucose levels, enhanced insulin sensitivity, and promoted energy expenditure by stimulating the emergence of beige adipose cells from white adipose cells. In conclusion, we suggest that CO acts as a potent inducer of FGF21 expression and that CO critically depends on FGF21 to regulate metabolic homeostasis.—Joe, Y., Kim, S., Kim, H. J., Park, J., Chen, Y., Park, H.-J., Jekal, S.-J., Ryter, S. W., Kim, U. H., Chung, H. T. FGF21 induced by carbon monoxide mediates metabolic homeostasis <I>via</I> the PERK/ATF4 pathway.</P>

The effects of Internet addiction on the lifestyle and dietary behavior of Korean adolescents

Yeonsoo Kim,Jin Young Park,Sung Byuk Kim,In-Kyung Jung,Yun Sook Lim,Jung-Hyun Kim 한국영양학회 2010 Nutrition Research and Practice Vol.4 No.1

We performed this study to examine lifestyle patterns and dietary behavior based on the level of Internet addiction of Korean adolescents. Data were collected from 853 Korean junior high school students. The level of Internet addiction was determined based on the Korean Internet addiction self-scale short form for youth, and students were classified as high-risk Internet users, potential-risk Internet users, and no risk Internet users. The associations between the students’ levels of Internet addiction and lifestyle patterns and dietary behavior were analyzed using a chi-square test. Irregular bedtimes and the use of alcohol and tobacco were higher in high-risk Internet users than no risk Internet users. Moreover, in high-risk Internet users, irregular dietary behavior due to the loss of appetite, a high frequency of skipping meals, and snacking might cause imbalances in nutritional intake. Diet quality in high-risk Internet users was also worse than in potential-risk Internet users and no risk Internet users. We demonstrated in this study that high-risk Internet users have inappropriate dietary behavior and poor diet quality, which could result in stunted growth and development. Therefore, nutrition education targeting high-risk Internet users should be conducted to ensure proper growth and development.

Backstepping control integrated with model predictive control for selective catalytic reduction system of diesel vehicle

Yeonsoo Kim,Changho Jung,Chang Hwan Kim,Yong Wha Kim,Jong Min Lee 제어로봇시스템학회 2018 제어로봇시스템학회 국제학술대회 논문집 Vol.2018 No.10

NOx emission from diesel vehicles has become an environmental problem, and regulatory standards have been strengthened with the real driving test. Selective catalytic reduction (SCR) with an active urea dosing system is one of the promising aftertreatment systems for both heavy- and light-duty vehicles. This study proposes backstepping control integrated with model predictive control to determine the amount of urea dosing. First, we prove that the subsystem of SCR is input-to-state stable with respect to the disturbances regardless of the value of the coverage fraction. Second, the desired coverage fraction of the catalyst is determined by solving the finite-horizon optimal control problem with the information of measurable disturbances. The backstepping control approach is then applied to determine the value of the manipulated input to achieve the desired coverage fraction. Compared to the results of the backstepping controller with a fixed coverage fraction setpoint, the proposed controller can reduce SCR-out NOx by 1.91 % using 0.24 % less amount of SCR-in NH₃. In addition, the total efficiency of NH₃ usage by the proposed controller is always higher than that of the backstepping controller with a coverage setpoint of 0.1.

Dietary intake based on physical activity level in Korean elementary school students

Yeonsoo Kim,Hyun A Kim,Jung-Hyun Kim,Yuri Kim,Yunsook Lim 한국영양학회 2010 Nutrition Research and Practice Vol.4 No.4

Prevalence of childhood obesity is increasing significantly worldwide due to energy imbalance perhaps stemming from undesirable dietary behavior and physical activity level. The objective of the study was to examine the effects of physical activity level on nutritional status in elementary school students. The subjects were comprised of 287 elementary school students between 4th and 6th grades in Seoul, Korea. The level of physical activity was scored with a modified Godin leisure-time exercise questionnaire and was categorized as active, moderately active, and sedentary. Dietary intakes were obtained using a 24-hour food recall method. An analysis of variance (ANOVA) was conducted to test for global significant differences of nutrient intakes by physical activity level. Boys were more active than girls. Daily intakes of energy in moderately active boys were significantly higher than in the sedentary group, but intakes of calcium and iron in moderately active boys were lower than active boys. For girls, physical activity level did not affect nutrient density at all. Intakes of calcium, vitamin C, and folate for both boys and girls were below 50% of recommended intake. Physical activity did not affect nutrient density and our participants were exposed to nutritional imbalance. Therefore, the results suggest that nutrition education regarding balanced diet and optimum physical activity is required for children's health and growth.

Taurine Chloramine Stimulates Efferocytosis Through Upregulation of Nrf2-Mediated Heme Oxygenase-1 Expression in Murine Macrophages: Possible Involvement of Carbon Monoxide

Kim, Wonki,Kim, Hoon-Ui,Lee, Ha-Na,Kim, Seung Hyeon,Kim, Chaekyun,Cha, Young-Nam,Joe, Yeonsoo,Chung, Hun Taeg,Jang, Jaebong,Kim, Kyeojin,Suh, Young-Ger,Jin, Hyeon-Ok,Lee, Jin Kyung,Surh, Young-Joon Mary Ann Liebert 2015 ANTIOXIDANTS AND REDOX SIGNALING Vol.23 No.2

Taurine chloramine potentiates phagocytic activity of peritoneal macrophages through up‐regulation of dectin‐1 mediated by heme oxygenase‐1‐derived carbon monoxide

Kim, Seung Hyeon,Zhong, Xiancai,Kim, Wonki,Kim, Kyeojin,Suh, Young‐,Ger,Kim, Chaekyun,Joe, Yeonsoo,Chung, Hun Taeg,Cha, Young‐,Nam,Surh, Young‐,Joon Federation of American Society for Experimental Bi 2018 The FASEB Journal Vol.32 No.4

<P>Resolution of inflammation that occurs after microbial infection or tissue damage is an important physiologic process in maintaining or restoring host homeostasis. Taurine chloramine (TauCl) is formed by a reaction between taurine and hypochlorite in leukocytes, and it is especially abundant in activated neutrophils that encounter an oxidative burst. As neutrophils undergo apoptosis, TauCl is released to the extracellular matrix at the inflamed sites, thereby affecting coexisting macrophages in the inflammatory microenvironment. In this study, we investigated the role of TauCl in phagocytosis by macrophages during resolution of fungal infection-induced inflammation. We found that exogenous TauCl substantially increased the phagocytic efficiency of macrophages through up-regulation of dectin-1, a receptor for fungal beta-1,3-glucans, which is present on the membrane of macrophages. Our previous studies demonstrated the induction of heme oxygenase-1 (HO-1) expression in murine peritoneal macrophages treated with TauCl. In the present study, knocking out HO-1 or pharmacologic inhibition of HO-1 with zinc protoporphyrin IX attenuated the TauCl-induced expression of dectin-1 and subsequent phagocytosis. Furthermore, carbon monoxide (CO), a by-product of the HO-1-catalyzed reaction, induced expression of dectin-1 and potentiated phagocytic capability of the macrophages, which appeared to be mediated through up-regulation of peroxisome proliferator-activated receptor . Taken together, induction of HO-1 expression and subsequent CO production by TauCl are essential for phagocytosis of fungi by macrophages. Our results suggest that TauCl has important roles in host defense against fungal infection and has therapeutic potential in the management of inflammatory diseases.</P>

Multiobjective Optimal Design of a Lean NO_<i>x</i> Trap and Urealess Selective Catalytic Reduction Aftertreatment System under a Control Algorithm

Kim, Yeonsoo,Park, Taekyoon,Jung, Changho,Kim, Chang Hwan,Kim, Yong Wha,Lee, Jong Min American Chemical Society 2018 INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH - Vol.57 No.49

<P>A lean NO<SUB><I>x</I></SUB> trap (LNT) followed by selective catalytic reduction (SCR) without the urea injection system (LNT-urealess SCR, LNT-pSCR) has been developed to meet the stringent regulations on NO<SUB><I>x</I></SUB> emission. For the LNT-pSCR system to be commercialized, optimal design and control of the system are required. It is important to minimize the capital cost while satisfying the NO<SUB><I>x</I></SUB> regulation standards and minimizing fuel consumption. In this study, we propose a strategy to optimally design the lengths of the LNT and pSCR and tune control parameters by solving the multiobjective optimization problem and considering control logic simultaneously. For decision makers, NO<SUB><I>x</I></SUB> emission and capital cost are critical factors to consider. In addition, NH<SUB>3</SUB> slip and fuel loss caused by post injection must be considered. The Pareto optimal points are obtained by solving the biobjective optimization problem with respect to NO<SUB><I>x</I></SUB> emission and capital cost while the other factors are constrained. Among the Pareto optimal points, we suggest a set of design and control tuning parameters. To reduce NO<SUB><I>x</I></SUB> only by 0.41% more than the suggested system, the capital cost increases significantly by 21.82%. Meanwhile, the results of multiobjective optimization without considering the control logic (fixed timings and durations of the rich modes) are trivial, in that the amount of NO<SUB><I>x</I></SUB> reduction increases as the volume of the LNT-pSCR system increases.</P> [FIG OMISSION]</BR>

Genetic Diversity and Population Structure Analysis Using Genotyping by Sequencing-Derived SNPs in Pear Germplasm Accessions

Keumsun Kim,Sewon Oh,Hyeondae Han,Kidong Hwang,Min-Gi Lee,Suji Ahn,Jiyeon Kim,Yoon-Kyeong Kim,Yeonsoo Lee,Daeil Kim 한국원예학회 2017 한국원예학회 학술발표요지 Vol.2017 No.5

Carbon monoxide attenuates amyloidogenesis via down‐regulation of NF‐κB‐mediated BACE1 gene expression

Kim, Hyo Jeong,Joe, Yeonsoo,Chen, Yingqing,Park, Gyu Hwan,Kim, Uh‐,Hyun,Chung, Hun Taeg John Wiley and Sons Inc. 2019 Aging cell Vol.18 No.1

<P><B>Abstract</B></P><P>Amyloid‐β (Aβ) peptides, the major constituent of plaques, are generated by sequential proteolytic cleavage of the amyloid precursor protein (APP) via β‐secretase (BACE1) and the γ‐secretase complex. It has been proposed that the abnormal secretion and accumulation of Aβ are the initial causative events in the development of Alzheimer's disease (AD). Drugs modulating this pathway could be used for AD treatment. Previous studies indicated that carbon monoxide (CO), a product of heme oxygenase (HO)‐1, protects against Aβ‐induced toxicity and promotes neuroprotection. However, the mechanism underlying the mitigative effect of CO on Aβ levels and BACE1 expression is unclear. Here, we show that CO modulates cleavage of APP and Aβ production by decreasing BACE1 expression in vivo and in vitro. CO reduces Aβ levels and improves memory deficits in AD transgenic mice. The regulation of BACE1 expression by CO is dependent on nuclear factor‐kappa B (NF‐κB). Consistent with the negative role of SIRT1 in the NF‐κB activity, CO fails to evoke significant decrease in BACE1 expression in the presence of the SIRT1 inhibitor. Furthermore, CO attenuates elevation of BACE1 level in brains of 3xTg‐AD mouse model as well as mice fed high‐fat, high‐cholesterol diets. CO reduces the NF‐κB‐mediated transcription of BACE1 induced by the cholesterol oxidation product 27‐hydroxycholesterol or hydrogen peroxide. These data suggest that CO reduces the NF‐κB‐mediated BACE1 transcription and consequently decreases Aβ production. Our study provides novel mechanisms by which CO reduces BACE1 expression and Aβ production and may be an effective agent for AD treatment.</P>