간내 담석과 동반된 간내 담도암에서의 p53과 Ki-ras의 발현

김명환,이성구,서동완,이승규,남승우,박능화,민영일,김연석,심기남,공경엽 대한소화기학회 1997 대한소화기학회지 Vol.30 No.5

Background/Aims: Hepatolithiasis or primary intrahepatic stones may be accompanied later by intrahepatic cholangiocarcinoma. This cancerous lesion is frequently associated with atypical hyperplastic epithelium that was suspected of being precancerous. To investigate the Ki-ras or p53 mutation may play a role in carcinogenesis, and to determine whether atypical hyperplastic epithelium may be precancerous, this study was performed in intrahepatic cholangiocarcinomas associated with hepatolithiasis. Methods: We examined 12 patients with intrahepatic cholangiocarcinomas associated with hepatolithiasis. Ki-ras point mutations were assessed by direct DNA sequencing. Expressions of p53 protein were immunohistochemically assessed. The overexpression of p53 and point mutation of Ki-ras were examined in normal, hyperplastic, atypical hyperplastic, and can- cerous tissues separately. Results: The expressions of p53 protein were detected in 4 (33%) of 12 cholangiocarcinomas and Ki-ras point mutations at codon 12 were found in 2 (17%) of 12 cholangiocarcinomas. In those two carcinoma cases which contained the mutant sequence of Ki-ras, the same point mutation from wild type GGT (glycine) to GAT (aspartic acid) was. found in the associated atypical hyperplastic epithelium. However, none of the normal and hyperplastic epithelium harbored Ki-ras or p53 mutations. Conclusions: The overexpression of p53 may play a part in the carcinogenesis of some intrahepatic cholangiocarcinomas associated with hepatolithiasis, whereas the role of Ki-ras mutations in those cases is dubious. However, Ki-ras point mutation at codon 12 may be responsible for either cancer or atypical hyperplastic epithelium associated with hepatolithiasis in certain cases, suggesting atypical hyperplastic epithelium may give rise to carcinoma.

건축공사시방서에서의 KS규격의 국제인증방안에 관한 연구

김경식,이재섭,김용수,이규진,조용훈,최완철,전재열,이현수,구재동,이기환 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

The purpose of this research is make out construction specifications for International Construction. Using off-shore products incur cost increase and longer delivery term of construction. and inconvenient on International Construction. Expand the range of additional local products conforming to performance. Life Cycle Cost. maintainability. operability. user's acceptability, etc.. And this study is suggest the standard formats and the techniques for construction specification.

스포츠에 의한 성장기 요추추체종판 장해 분석

김민섭,이종영,이충영,이승훈,임완기,강은균,이종호 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.2

Apophyseopathy in human growing-up period is divided in three parts, early stage, advancing stage, and ending stage which are analyzed by X-ray test. The tuber of kantenabtrennung, schmorl and rear oxhorn dissociation are one of the these barrier process. We assume that the fracture of apophysis by overusing is the main cause of these barriers.

정밀여과 공정에서의 역세척에 관한 연구

이기완,최충현,이남경 동신대학교 환경연구소 1999 환경연구 Vol.4 No.1

정수처리 공정의 원수 및 응집/침전 상징수와 하수처리 공정의 원수를 대상으로 MF를 적용하여, 각 시료수의 역세척 특성을 파악하였다. MF의 여과지속기간은 시료수의 투과속도가 1/2로 감소되는 시점과 여과압력은 1 kg/cm²의 조건에서 실험을 수행하였다. MF의 투과속도는 정수 및 하수처리 공정의 원수인 경우 1시간이내, 정수처리 공정의 응집/침전 상징수인 경우 2시간 이내로 나타났다. 정수 및 하수처리 공정의 원수인 경우 MF의 역세 회복율 및 역세 소요시간은 각각98%와 5~6분 및 7~8분으로 나타났다. The backwashing characteristics of three kinds of sample water was studied with the application of MF(Micro Filtration) process. The three kinds are raw water and clarified water at water treatment process and raw water at sewage treatment process. The tests were performed with the filtering duration of MF to the half permeability arriving time and the filtering pressure 1 kg/㎠. The MF permeability of the raw water at the both process was less than 1 hour and that of the clarified water at water treatment process was less than 2 hour. The recovery rate and the consume time of backwashing for the raw water were 98%, 5-6 minutes and 99%, 7-8 minutes at the water and sewage treatment process, respectively.

光州地域 工業團地의 廢水排出 特性과 效率的 管理

李基完 동신대학교 환경연구소 1995 환경연구 Vol.1 No.1

광주지역의 공단폐수처리 및 관리에 관한 연구를 수행하였으며 기존씨스템의 현황과 문제점 분석을 통하여 얻은 결과는 다음과 같다. 즉, 광주지역에는 4개 공단이 있는데 폐수배출을 주도하는 업종은 금속광물류이며 가장 큰 BOD원은 본촌공단으로서 총 BOD부하량의 65.6%를 점유하고 있다. 단위업소당 평균유량을 기준한 폐수발생비중이 큰 순서는 음·식료, 금속·광물류, 섬유류 순 이었고 용수사용에 대한 폐수사용 비율은 음·식료와 금속·광물류 0.56, 섬유류 0.85 로서 폐수의 체계적 관리를 위하여는 업소에서의 계통별 물수지분석이 긴요한 것으로 판단되었다. 업종별 방류수의 S-BOD_(5), S-COD_(Mn), S-COD_(Cr), 농도는 각각 3∼83mg/ℓ, 7∼140mg/ℓ, 20∼900mg/ℓ로서 수질규제 기준에 만족된 수준이라 할 수는 없는 상황이었으며, 더욱 엄격한 관리를 위하여는 BOD농도보다 COD농도에 관심을 가져야 하고, 특히 COD에 있어서도 앞으로 강화될 수질규제에 능동적으로 대응하려면 KMnO₄법보다는 K₂Cr₂O_(7), 법에 의한 측정수단이 더욱 효과적일 것으로 판단되었다. 공단업소 대부분의 방류수는 k(유기물 분해속도상수)값이 0.006∼0.024day^(-1), (BOD/COD)比 0.024∼0.325로서 상당량의 난분해성 유기물질이 포함되어 있는 것으로 판단되었다. 업소는 급변하는 국제정세에 부응하여 환경문제와 관련된 사내 외 교육체계를 유지할 필요가 있다. 또한, 기존의 개별업소 폐수처리방식은 그룹화된 유사업종별 공동방지시설 운영방식으로 개선될 필요가 있으며 이 경우, 공동방지시설의 처리공법은 BOD보다는 COD중심으로 검토함이 바람직할 것으로 판단되었다. A study on the management and treatment of industrial wastewater in Industrial Parks of Kwang-Ju has been performed. The obtained results from the experiments or the literatural data analyses of the present status and problems on the existing systems for wastewater were as follows; There are four Industrial Parks in Kwang-Ju and metals & minerals industries take the lead in discharge of industrial wastewater. The biggest BOD source in four industrial parks is Bon-Chon Industrial Park with 65.6% of total BOD loads. The biggest effluent flow among the industries is the beverage or foods industry on base of average flowrate per each similar factory by industry, and the second of big industry is metals & minerals (42 %), the third is fibers (8 %) in mass order. The estimated flowrate ratios of the effluent wastewater to the supply water were 0.56 in beverage or foods industry, 0.85 in metals & minerals respectively. So, it was considered that analyses about the flow balance of water from supply step to effluent step are important for the effective and systimetical management of industrial wastewater. Concentrations of the effluent wastewater for factories to be surveyed are 3∼83mg/ℓ, 7∼140mg/ℓ and 20∼900mg/ℓ, respectively for S-BOD_(5), S-COD_(Mn) and S-COD_(Cr). These qualities are not enough to satisfy the legal regulation, therefore it was considered that COD base is desireable than BOD base in the parameter of water quality for the more strict management. Especially also in COD concentration, COD_(Cr), concentration by the potassium dicromate(K₂Cr₂O_(7)) method would be better than the potssium permanganate (KMnO₄) method for the more active mamagement of water quality. As for the BOD/COD correlations of the effluent with 0.006∼0.024 day^(-1) of k values, ratios of them are 0.024 ∼ 0.325, and it was estimated that a much of non-biodegradable organic matters should be contained in most of effluent wastewater from Industrial Parks. The company or factory needs to make inside- or outside-education systems related with environmental problems tighten a little more for the rapidly changing international situation in near future. And also, it was considered that the joint treatment system by group would be better than the existing individual treatment system for the similar factories and the treatment method is to be reformed from the BOD first management order to the COD first.

사회체육 동호인의 자아개념과 생활 만족도의 관계

이제홍;김진규;김완기 순천향대학교 기초과학연구소 2010 순천향자연과학연구 논문집 Vol.16 No.2

This study intends to offer the basic data by clarifying the relation between the self-concept of sport and leisure studies members' and the life satisfaction so that it can develop the social sports activities, spread them and improve the life quality through the righteous and useful leisure. In addition, the sound sport activities can be activated and the clubs can be expanded and finally contribute to improvement of the life quality, self- actualization, happiness, maintaining and improving heath. The sport club members in Daejeon have been set as a population and then the sample has been selected by a group sampling and a random sampling. In this study, total 360 sheets of questionnaire have been collected and 15 sheets have been eliminated because of their lack of confidence. Available 345 sheets have been inputted one by one, and the data processed by SPSS 14.0 for the analysis purpose. The specific conclusion is as follows. The self-concept of social sport club members and life satisfaction 1) The general, social, emotional and physical self- concept of members has a meaningful effect on the past life satisfaction. 2) The general, social, emotional and physical self- concept of members has a meaningful effect on the present satisfaction 3) The general, familial, emotional and physical self- concept of members has a meaningful effect on the future satisfaction.

도시공학 핵심과목의 심화교육 프로그램 개발에 관한 연구

이완영,백기영,김영환,장세봉 永同工科大學校 1996 硏究論叢 Vol.2 No.1

본 연구는 핵심과목 요목의 작성과 난이도별 문제은행의 지도과정, 핵심과목에 대한 자율학습 문제은행을 데이타베이스화하여 상시 활용화 추구, 교수와 학생의 상호 협동시스템에 의한 학습방법론 도출을 시도하였다. 시론적 성격에 한정되어 있긴 하나 본 연구는 협동시스템을 기반으로한 자율학습모형을 구축함으로써 학습과 교육효과 제고, 협동심과 선의의 경쟁을 매개로 하는 생활구현, 취업대비 등의 목표에 기여하는데 의의가 있다. This paper examines that drawing up a syllabus of core courses and an item pool classified by the degree of difficulty, and that inquiring practical use an databased item pool, and that proposing study method by cooperative system between students and professors. The result of this study is expected to contribute to studying, life, and taking up an occupation by constructing autonomous study model founded the cooperative system.

高密度 魚類養殖을 위한 效率的인 循環水 處理씨스템에 관한 硏究

李基完,羅德寬 순천대학교 공업기술연구소 1992 工業技術硏究所論文集 Vol.6 No.-

The purpose of this paper is to development the more effective treatment system of recycling water for the high-density fishfarming. Investigations through analysis of quality for the fishfarming water and the experimental treatment using the designed system with Biological Fluidized Bed(BFB) reactor have been performed for the recycling water in fishfarming. The obtained results showed that water quality in breeding pond was affected by the light cycle and vitalities of fishes and recycle flow range showing the most effective solid removal rates of the settler in system which was designed specially was near of 0.25ℓ/sec. Oxygen transfer rates in the aeration system consistes of four-column tower were in proportion to recycling flow rates of water. And also, the effluent BOD load in biological water treatment system using BFB reactor could be decreased to 65% than other existing water reuse aquaculture system with filter media.

Unrecorded Marine Algae From Korea II

이기완 濟州大學校 師範大學 科學敎育硏究所 1984 科學敎育 Vol.1 No.-

Comparison of the Pharmacological Effects of Roasted and Non-roasted Zizyphi Spinosi Semen: Differences in Chemical Constituents

홍학기, 이기남, 마유안, 김윤배, 남상윤, 송인섭, 문동철, 오기완 충북대학교 동물의학연구소 2008 Journal of Biomedical and Translational Research Vol.9 No.3

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