직장 카르시노이드 종양에서 Ki-67 발현의 예후적 중요성

홍수민 ( Su Min Hong ),김유선 ( You Sun Kim ),문정섭 ( Jung Seop Moon ),김진남 ( Jin Nam Kim ),오명기 ( Myoung Ki Oh ),권선옥 ( Sun Ok Kwon ),정성연 ( Seong Yeon Jeong ),홍성우 ( Seong Woo Hong ),강윤경 ( Yun Kyung Kang ) 대한소화기학회 2013 대한소화기학회지 Vol.61 No.2

Background/Aims: Rectal carcinoid tumors can be resected with endoscopy, and it is important to assess their prognostic factors. We evaluated the potential of Ki-67 expression as a prognostic factor in rectal carcinoid tumors. Methods: We retrospectively reviewed the medical records of 37 patients with rectal carcinoid tumors who got endoscopic resection from January 2001 to January 2011 at Inje University Seoul Paik Hospital. We analyzed their endoscopic and histologic findings, Ki-67 expression, clinical outcome, and prognosis. Results: The mean age (±SD) of the patients was 56.3±10.7 years, and the male : female ratio was 3.6:1. The mean tumor size was 0.5±0.4 cm, 33 patients showed grade 1 tumors (89.2%) and the average Ki-67 expression was 0.7±1.2%. Thirty five patients underwent endoscopic mucosal resection, and two required endoscopic submucosal dissection. Eight patients had positive margins after resection, but no cases of lymphovascular invasion were identified. The median follow-up duration was 21.4±25.4 months, and no recurrences were observed. Conclusions: In low grade rectal carcinoid tumors which are lack of central depression on colonoscopy, the expression of a molecular marker of malignant potential, Ki-67, was low. Therefore, endoscopic resection seemed to be a safe and effective treatment for these tumors.

HFC-134a와 대체냉매 HFC-152a에 CF_3I를 혼합한 자동차냉매 특성

권일욱,박찬수,홍경한,문기선,최운수,서의경,윤갑식,이종인,하옥남 朝鮮大學校 機械技術硏究所 2002 機械技術硏究 Vol.5 No.1

These days, an attention of environment has been increasing all over the world. to prevent the green house effect and destruction of an ozone layer, an ozone destruction potential(ODP) be zero and a refrigerant for low global warming potential(GWP) is needed. HFC-134a, in which hydrogen is mixed instead of chlorine is a refrigerant used for automobile conditioners and its destruction potential is ecologically zero. However, it is not considered as a perfect substitutive refrigerant as its GWP is high. It is studied refrigerant mixtures in which HFC-134a, HFC-152a and CF_3I with low GWP and zero ODP are mixed by experimentally and concluded as follows; 1. with the variation of speed of compressor outside temperature and flow rate, the heat of evaporator and compressor and coefficient of performance was varied, and influenced the air conditioner. 2. The pressure of evaporator was decreased with increasing the speed of compressor and that of the refrigerant HFC-134a was higher 21% than that of azotrope refrigerant mixed with CF_3I. The overall capacity of condensor and evaporator was increased and HGC-134a was higher than azotrope refrigerant mixed with CF_3I 3. The capacity of evaporator with the refrigerant HFC-134a was higher 6% than azotrope refrigerant mixed with CF31 and the required power with zaotrope refrigerant mixed with CF_3I was higher 11% than that of HFC-134a. 4. The COP of the refrigerant FHC-134a was higher 31% in 1000RPM. when outside temperature was increased, COP was decreased. 5. Performance of HFC-134a is better than azotrope refrigerant mixed with CF_3I but prefered zaotrope refrigerant mixed with CF_3I considering the environment.

主觀的인 評價에 의한 靑少年의 肥滿傾向 分析

權善鈺,金基學,李東洙,鄭鎭國 慶北大學校 師範大學 體育學硏究會 1992 體育學會誌 Vol.20 No.-

This study was conducted to analyze the tendency of obesity by subjective evaluation method in measuring the skinfold thickness in adolescents. The validity norms were height, weight, the sum of skinfold thickness, Db1, %Fat1, %Fat2, and BMI. The subjects surveyed were 2,442 boy and girl students of middle and high school in medium and small city and big city. The results are summarized as follows; 1. Weight of adolescents evaluated as obesity was over 76㎏ in boy's middle, over 67㎏ in gril's middle school, over 79㎏ in boy's high school, and over 68㎏ in girl's high school, the sum of skinfold thickness was over 40㎜, over 39㎜, over 54㎜, and over 41㎜ respectively. 2. Except the case of height in girl's middle, boy's high and girl's high school, in height in boy's middle, weight, the skinfold thickness, Db1, %Fat1, %Fat2, and BMI, difference among the degree of obesity evaluated subjectively was significant(p<.05). 3. Except heigh in girl's middle, boy's and girl's high school, correlation between the degree of obesity evaluated subjectively and height in girl's middle school, weight, the sum of skinfold thickness, Db1, %Fat1, %Fat2, BMI respectively was high and significant(p<.01 or p<.001) Therefore, on the basis of above results, I think we can evaluate the tendency of obesity in adolescents validly by subjective evaluation method as well.

한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

成人의 身體組成 評價를 위한 生體電氣低抗法의 妥當性 檢討

李東洙,金基學,梁金山,權善鈺 慶北大學校 師範大學 體育學硏究會 1992 體育學會誌 Vol.20 No.-

This study is concerned with a comparison of the UW and the BI methods as they are applied to the evaluation of body composition. The validity of the BI method is studied in detail, and the SFT method is also examined in detail in comparison with the other methods. Altogether 49 healthy adults(13 males and 36 females)were estimated, and the following results have been obtained: 1. A comparison of the % body fat measured by the three methods is schematically summarized below: ◁표 삽입▷(원문을 참조하세요) 2. There was a higher correlation between the UW and the BI methods than between the UW and the SFT methods in the estimate of the body composition. 3. The measurements of the %body fat, the height and weight, and the fat thickness by means of the UW method did not reveal significant correlation with respect to the physical constitution of the males, but there was a significant correlation(0.5754) with respect to the weight of the females. 4. In the estimated of the % body fat, the BI method showed a smaller standard and relative deviation than the SFT method both for the male and the female subjects, and the highest degree of accuracy was obtained in the BI method applied to the male subjects.

공기중의 Radon 방사능 측정에 의한 서울 대기의 혼합높이 결정

김의훈,김필수,김채옥,이건상,권기덕 漢陽大學校 環境科學硏究所 1985 環境科學論文集 Vol.6 No.-

서울 대기의 혼합높이를 1984년1월부터 4월 사이에 지표고도에서 측정한 ??으로부터 결정하였다. ?? 농도로부터 상당혼합높이를 계산하기 위하여 한 수식 모델을 개발하였다. 이로부터 계산한 상당혼합높이는 늦은 오후에 최고 및 밤 또는 이른 아침에 최저값을 가지며 수 십 미터에서 1킬로미터 또는 그 이상의 높이를 보이는 일변화를 나타냈다. 평균혼합높이는 겨울이 낮았다. 이와 같은 변화는 대기의 안정도, 일조시간, 기온 등 대기의 인자와 밀접한 관계가 있었다. The mixing heigt of the atmosphere in Seoul was determined from the measurement of ?? concentration in air at ground level for January 1984 to April 1984. In order to calculate the equivalent mixing height from ?? concentration, a mathematical model was developed. The equivalent mixing heights calculated from this model showed diurnal variation with the highest values in the late afternoon and the lowest during night hours or early morning ranging from several tens to one thousand meters or more. The average heights represented lower values in the winter. These variations were closely related to the atmospheric factors, such as atmospheric stability, daytime hour, and temperature, etc.

다발성 대장암 간전이 환자의 간절제를 위한 새로운 시도

주종우,김형철,임철완,신응진,조규석,유기원,송옥평,홍대식,박성진,조준희,이혜경,김희경,권계원,고은석 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Multiple bilobar liver matastases (MBLM) are the main cause of low resectability in the colon cancer liver metastases. The authors experienced one case of initially non-resectable colon cancer liver metastases. He was curatively and safely treated with a two-stage hepatectomy using the new method of future remnant liver volume growing. A 54-year-old man was referred to our department with the sigmoid colon cancer combined with MBLM, which were checked in two small metastatic lesions in the left lobe and five large sized lesions in the right lobe in the computed tomogram (CT). A laparoscopic assisted anterior resection was primarily performed. We performed the 1^(st) stage hepatectomy 3 weeks after the colon resection. Intra-operative Ultrasonogram (US) found 9 small superficial metastatic lesions in the left lobe. All that lesions were completely removed by non-anatomical wedge resection. An occlusion ballon catheter was placed in the right portal vein through a small branch of the inferior mesenteric vein at that time. The future remnant liver volume was sufficiently increased 3 weeks after the 1^(st) hepatectomy. A right hepatectomy was safely performed 22 days after the 1^(st) hepatectomy. The patient received a regional chemotherapy (interleukin2 based immuno-chemotherapy through hepatic artery) for 4 months, then received 9 cycles of systemic chemotherapy (biweekly Oxaliplation, leucovorin, plus 5-fluorouracil) without any recurrence evidence.

Long-range Order of Supramolecular Dendrimer

Ki-Ok Kwon,Kang Ho Park,Hee-Tae Jung 한국고분자학회 2016 한국고분자학회 학술대회 연구논문 초록집 Vol.41 No.2

지각된 부모의 심리적 통제가 아동의 우울과 사회적 불안에 미치는 영향

권기옥 ( Ki-ok Kwon ),박성옥 ( Sung-ok Park ) 한국영유아아동정신건강학회 2014 영유아아동정신건강연구 Vol.7 No.1

본 연구의 목적은 지각된 부모의 심리적 통제가 아동의 우울과 사회불안에 미치는 영향을 확인하는 것이었다. 본 연구의 대상자는 대전시 서구와 동구에 소재한 2개 초등학교에 재학 중인 5, 6학년 185명이었으며, 자료의 통계처리는 SPSS version 18.0을 이용하여 빈도, 백분율, 평균과 표준편차분석, 차이검증, 상관관계분석, 회귀분석 등을 실시하였다. 연구결과는 다음과 같다. 첫째, 아동의 성별 에 따라 부모의 심리적 통제와 사회불안에서 유의미한 차이가 나타나지 않았으나 우울에서는 유의미한 차이를 보였다. 둘째, 부모의 심리적 통제는 우울 및 사회불안과 정적 상관관계를 갖는 것으로 나타났다. 셋째, 부모의 심리적 통제가 아동의 우울과 사회적 불안에 정적 영향을 미치는 것으로 나타났다. 부모의 심리적 통제가 우울의 각 하위요인에 미치는 영향을 살펴보면, 우울정서와 자기비하 에 영향을 미쳤으며, 부모의 심리적 통제가 사회적 불안의 각 하위요인에 미치는 영향을 살펴보면 수행불안, 부정평가, 회피행동, 낯선 두려움, 비주장성에 영향을 미치는 것으로 나타났다. The purpose of this study is to examine the effects of parents' psychological control on depression and social anxiety of children. Participants of this study were 185 children in fifth and sixth grades from two elementary schools at Seo-Gu and Dong-Gu in Daejeon. Data analysis was conducted by SPSS 18.0. The findings are as follows. First, no significant difference was found between the parents' psychological control and the children's social anxiety in terms of gender of the children. However, significant difference was found between the parents' psychological control and depression of the children. Second, psychological control by the parents showed a positive correlation with depression and social anxiety of the children. Third, regression analysis found parents' psychological control influenced depression and social anxiety of the children although no significant difference was found. Parents' psychological control influenced depression and self-deprecation in the domain of depression and affected performance anxiety, negative evaluation, avoidance behavior, fear of strangers, non-assertiveness in the social anxiety domain.

원유중의 잔류항생물질 및 썰파제 조사

박병옥 ( Byoung Ok Park ),백미순 ( Mi Soon Back ),권기호 ( Ki Ho Kwon ),우기방 ( Ki Bang Woo ),장기윤 ( Ki Yoon Chang ) 한국가축위생학회 1991 韓國家畜衛生學會誌 Vol.14 No.1

Antibiotic residues of raw milks collected in Anyang area were tested by TTC-reduction test, EEC-4plate method and TLC(SOS-kit) method to improve and monitor the quality of milk. Antibiotic substances were not detected from 100 raw milk samples, but sulfamethazine was detected from only one sample(1.3PPM) by SOS test. Unclassified anti-microbic substances were detected from 22 samples by EEC-4 plate method. EEC-4 plate test was useful to categorize the species of antibacterial substances and SOS test was useful to detect the sulfamethazine field screening test.