이상와 누공(piriform sinus fistula)에 기인한 재발성 화농성 갑상선염 1예 : A Route of Infection in Recurrent Suppurative Thyroiditis

양근호,김홍주,김기환 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.4

Piriform sinus fistula, believed as an embryonic remnant of the third or forth pharyngeal pouch, is an extremely rare and newly recognized entity that lead to acute suppurative cervical infection. Recently, reports of acute suppurative thyroiditis and anterior neck abscess due to piriform sinus fistula have been increasing in number, though an extensive review of the literature reveals that about 60 cases of this condition have been reported. The sinus may be overlooked for years and the patient may undergo multiple procedures before the diagnosis is properly made and treated. We have experienced such a case of recurrent suppuative thyroidits in which coexisting piriform sinus fistula was identified by intra-operative endoscopic examinaton. This report reviews the embryological development of the sinus and the clinical symptoms and treatment of this condition.

음낭내 낭포성 림프관종 1례

양근호,김홍주,김기환 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.4

Cystic lymphangiomas are congenital lymphatic hamartomas of which half are present at birth, 90% are evident by age 2 years and 95% occur in the neck or axilla. Scrotal cystic lymphangioma is rare with approximately 50 cases reported. The lesion is commonly misdiagnosed as hernia. hydrocele, spermatocele and acute scrotal condition, resulting in improper selection of incision, incomplete excision and recurrence, We present a case of 2 year 9 month old male with the scrotal lymphangioma that have not any connection with the testis or spermatic cord.

2-Cinnamoylthiophene에 대한 Cysteine의 반응 Mechanism에 관한 연구

맹주양,鄭昌雄,張聖根 순천향 대학교 1984 논문집 Vol.7 No.2

The kinetics and mechanism of nucleophilic addition of L-Cysteine to 2-Cinnamoylthiophene over wide pH range were presented and analyzed in detail. The rate constants were determined with UV-spectrophotometer in 50% methanol-water solvent at 25℃. The rate equation which can be applid to over wide pH range was obtained k=?? Anaysis of rate constants suggests that below pH 10, the reaction is initiated by the attack of cysteine molecule, and above pH 12.5, deprotonated cysteine ion attack the molecule.

信賴性 制約條件을 고려한 鋼材 트러스構造의 最適設計

邊根周,韓相勳,梁在成 연세대학교 산업기술연구소 1982 논문집 Vol.14 No.1

The reliability analysis of truss members is considered and a relationship between the reliability and the optimization is established. The applications of optimization techniques to the minimum weight design of the trusses are discussed. Finally a optimization algorithm of designing truss members for minimum weight to obtain a specified reliability index is presented. The reliability based optimum design of plane truss structures is conidered on some detail. The crosssectional dimensions of the structures are considered as random design variables. The constrained opti-mization problems are solved by using the SUMT (Modified Newton-Raphson Method) and the Rosenbrock's Hill technique. Numerical examples are presented to illustrate the computationl effectiveness of the two algorithms presented. It has been obesrved that the SUMT algorithm may be considered as a very efficient and accurate solution technique in the structural optimum design problem with the reliability constraints.

근위 경골과 골절의 수술적 치료

송경진,양근호,이주홍 대한골절학회 2002 대한골절학회지 Vol.15 No.4

서 론 : 경골과 골절의 치료 목적은 가능한 한 정확한 관절면의 정복, 골절의 견고한 고정과 유지 및 손상된 인대의 안전성을 재건시켜주고 조기 관절운동을 시킴으로써 슬관절의 기능을 회복시키는데 있다. 수술을 시행한 경골과 골절 환자의 치료결과를 비교하고 합병증 등의 임상분석을 통해 향후 치료지침을 제시하고자 하였다. 연구대상 및 방법 : 최근 5년 동안 본원에서 치료한 환자 27례를 대상으로 하였으며 추시 기간은 12개월에서 62개월로 평균 37개월 이였다. 남자가 19례(70.4%), 여자가 8례(29.6%)였으며, 연령 분포는 24세에서 78세로 평균 53세였다. 골절의 분류로는 Schatzker 분류법으로 하였으며 제 Ⅰ 형 3례(11.1%), Ⅱ형 1례(3.7%), Ⅲ형 0례(0%), Ⅳ형 3례(11.1%). Ⅴ형 1례(3.7%) 그리고 Ⅵ형 19례로 Ⅵ형이 가장 많은 빈도를 나타냈다. 27례 모든 환자에서 수술적 치료를 시행하였으며, 필요한 경우 골 결손부에 골 이식술을 병행하였다. 치료 결과는 Blokker의 판정기준으로 평가하였다. 결 과 : 관혈적 정복의 유지를 위한 금속 내고정물로는 나사못 사용이 4례(14.8%), 금속판 사용이 23례*85.2%)였고 이중 제 Ⅵ형 10례(27.0%)에서 골 이식술을 시행하였다. 술 후 합병증은 총 27례 환자 중 10례 환자에서 발생하여 37%를 나타내었으며 운동장애가 3례, 각 형성이 3례, 감염은 3례에서 발생하였고 그 외 외상성 관절염 소견으로 인한 동통을 보인 경우가 1례에서 있었다. Blokker의 판정기준으로 평가하여 22례(81.5%)에서 양호한 결과를 얻었다. 결 론 : 근위 경골과 골절의 수술적 치료시 골절부의 연부조직이 허용하는 한 해부학적 정복은 물론이며 금속판 및 나사못을 이용한 견고한 내고정을 실시하는 것이 술 후 조기 관절운동을 가능하게 하고, 합병증의 가능성을 낮출 수 있을 것으로 사료된다. Introduction : The purpose of this study was to analyze the results, prognosis and complications in the treatment of proximal tibia plateau fractures, and to suggest the guideline for the proper management in the difficult cases of tibial plateau fracture. Materials and Methods : We have analyzed 27 cases, which surgically treated during recent five years with average 36.6 months follow-up. Patients ranged in age from 24 to 83 years at the time of hospitalization, consisting of 19 males(70.4%) and 8 females(29.6%). The type of fracture by Schtzker classification revealed in type Ⅰ 3cases(11.1%), type Ⅱ 1 case(3.7%), type Ⅲ 0 case(0%), type Ⅳ 3 cases (11.1%), type Ⅴ 1 case(3.7%) and type Ⅵ 19 cases(70.4%). The associated injury occurred in 22 cases(81.5%), most of them were ipsilateral fibular, ipsilateral femoral and radioulnar fractures. The results were evaluated by Blokker's criteria. Results : Screw fixation was done in 4 cases(18%) and plate fixation in 23 cases(85.2%), and bone grafting was done in 10 cases(37.0%). There were 10 postoperative complications with 3 cases of knee ankyosis, 3 cases of angular deformity, 3 cases of infection, and 1 case of traumatic arthritis. According to Blokker's criteria, 22 cases(81.5%) had satisfactory results. Conclusions : Accurate anatomical reduction and rigid internal fixation of the proximal tibial plateau fracture enabled early motion and normalization of injured soft tissues, and also provided functional improvement of the knee.

외측 도달법을 이용한 종골 관절내 골절의 관혈적 정복

송경진,양근호,이주홍 대한골절학회 2002 대한골절학회지 Vol.15 No.4

목적 : 관절내 종골 골절에 대해 외측 도달법을 이용한 내고정을 시행 후 치료결과를 분석하여 그 유용성을 확인해보고자 하였다. 대상 및 방법 : 관절내 골절을 가지고 종골 골절의 경우 중 외측 도달법으로 내고정술을 시행하고 1년이상 추시 관찰이 가능했던 20명(21예)를 대상으로 하였다. 성별은 남자 17명, 여자 3명이었고 평균 33세(16~62세)이었으며, 원인별로는 추락사고가 14예이었고 나머지는 교통사고로 인한 골절이었다. 골절의 분류는 단순 방사선 사진상 Essex-Lopresti 분류를 이용하였고, 모든 예는 관절내 골절을 가지는 경우만 포함하였으며 이 중 관절 함몰형이 17예로 대부분이었고, 4례의 설상형은 심한 분쇄골절 양삼이었다. 술 전과 술 후 Bo¨hler 각의 변화를 비교하였고, 임상적 평가는 Paley와 Hall에 의한 평가 기준을 따랐다. 결과 : 수술 전 Bo¨hler 각은 평균 2.8에서 술 후 평균 25.1로 회복 되었고, 임상적 평가 상 우수 3예, 양호 13예, 보통 4예, 불량 1예이었다. 술 후 합병증으로 3예의 창상 열개, 1예의 감염, 1예의 비복신경 손상이 있었으먀, 추 후 합병증으로 일상 생활에 지장을 초래하는 정도의 족관절 운동범위 제한이 3예, 지속되는 동통이 3예, 외상성 관절염이 2예에서 확인되었다. 이 중 1 예에서 운동범위 제한과 동통이, 1예에서 운동제한과 외상성 관절염이 동시에 존재하였다. 1예는 창상 조직의 감염과 이에 따른 괴사로 자유 피판술을 시행하였다. 결론 : 분쇄가 심한 종골의 관절내 골절에서 외측 도달법은 거골하 관절을 직접 노출시켜 정확한 해부학적 복원과 견고한 내고정을 시행할 수 있고 신경 혈관 손상이 적어 유용한 방법으로 사료된다. Purpose : This study was designed to investigate the usefulness of lateral approach for accurate reduction and rigid internal fixation comminuted intra-articular fracture of calcaneus. Meterial and Method : Twenty patients(21 cases) who had inter-articular fracture of calcaneus and underwent an open reduction and internal fixation using lateral approach were enrolled. Using Essex-Lopresti classification, all cases were intra articular fracture, which joint depression type was 17 case and 4 of severe comminuted tongue type. We compared the preoperative and postoperative change of Bo¨hler’s angle and clinical results were analyzed using Paley and Halls evaluation protocol and scoring system. Results : The average Bo¨hler’s angle was restored from 2.8 to 25.1 after operations and clinical results classified 4 well, 12 good, 4 fair, 1 poor cases. Postoperative complications were 2 cases of wound dehiscence, 1 of infection and one had sural nerve injury. Late complocations included 3 cases of limitation of motion of ankle that disturb usual activity, 3 of sustained pain and 2 of traumatic arthritis and 2 cases had 2 complications at the same patients. Conclusion : The lateral approach is valuable for the comminuted intra-articular fractures of calcaneus that enables accurate anatomical reduction and rigid internal fixation by providing direct exposure of subtalar joint, and also with little morbidity of neurovascular injury.

유한요소법에 의한 콘크리트의 파괴진행해석

송하원,변근주,양재성 연세대학교 산업기술연구소 1994 논문집 Vol.26 No.2

Fracture machines does work for concrete, provided that one uses a proper, nonlinear form of fracture mechanics in which a finite nonlinear zone at fracture front is being considered. The fracture process zone is a region ahead of a traction-free crack, in which two major mechanisms, microcraking and bridging, play important rules. The development of model of fracture process zone is most important to describe fracture phenomena in concrete. The toughness due to bridging is dominant compared to the toughness induced by the microcracking, so that the bridging is the dominant mechanism governing the fracture process of concrete. In this paper the bridging zone, which is a part of extended macrocrack with stresses transmitted by aggregates in concrete, is modelled by a Dugdale-Barenblatt type model with linear tension-softening curve. Finite element techniques are shown for implementation of the model for the analyses of crack growth in concrete.

Ethyl-4-methoxybenzylidenecyanoacetate의 空間群

김문집,서일환,맹주양,오인근 순천향대학교 1985 논문집 Vol.8 No.4

The synthesis of Ethyl-4-methoxybenzylidenecyanoacetate was confirmed by IR spectrophotometer, NMR and Mass spectrometer. The crystal is monoclinic with a=8.63(1), b=8.43(1), c=17.38(2), β=91.6(1)°, Z=4 and space group P2₁/n, so that four molecules in a unit cell are arranged to have 2₁ screw symmetry along b-axis and n glide plane perpendicular to it.

Nitrostyrylphenylsulfone에 대한 Hydrogen Cyanide의 친핵성 첨가반응 메카니즘 연구

鄭昌雄,朴茂淳,明平根,孟柱煬 순천향대학교 1982 논문집 Vol.5 No.2

The rate constant of the nucleophilic addition reaction of hydrogen cyanide to p-Nitrostyrylphenylsulfone were determined at various pH and a rate equation which can be applied over wide pH range was obtained. Analysis of the equation suggest that below pH11, the nucleophilic addition reaction of hydrogen cyanide to p-Nitrostyrylphenylsulfone is initiated by the attack of hydrogen cyanaide molecule on the activated carbon double bond, and above PH 13 cyanide ion is the only nucleophile to p-Nitrostyrylphenylsulfone.

In Vitro Development and Chromosome Constitution of Porcine Parthenotes following Different Activation Treatments

Hae-Joo Wi,Dae-Jin Kwon,Joo-Hee Park,Choon-Keun Park,Boo-Keun Yang,Hee-Tae Cheong 한국동물생명공학회(구 한국동물번식학회) 2007 Reproductive & developmental biology Vol.31 No.4

This study was conducted to examine the protein kinase inhibitors, 6-dimethylaminopurine (DMAP) and cycloheximide (CHXM) on the development and chromosome constitution of porcine parthenogenetic embryos. In vitro matured oocytes were activated by electric stimuli (ES) or a combination of ES with culture in 2 mM DMAP or 10 μg/ml CHXM for 4 hr. Activated oocytes were cultured in PZM-3 for 6 days. Some 1-cell embryos and blastocysts were fixed by air dry method to analyze the chromosome constitutions and/or total cell number. Blastocyst development of DMAP-treated group (26.7%) was significantly higher (p<0.05) than those of CHXM-treated and ES control groups. Ploidy in 1-cell stage embryos was not different among groups (77.3 to 81.0%), however, proportion of diploid chromosome constitutions was high in DMAP-treated group (61.9%, p<0.05). In the blastocyst stage, proportion of diploid chromosome plates was significantly high in DMAP-treated group (64.2%, p<0.05), and proportion of abnormal chromosome plates was higher in CHXM-treated group (36.6%, p<0.05) than DMAP-treated group (28.3%,). Proportion of embryos with abnormal chromosome constitutions was slightly increased by DMAP (40.0%) and CHXM (42.1%) treatment due to the increasing of mixoploid (47.4 and 52.0%). The present study shows that the DMAP treatment increase the development of porcine parthenotes. However, parthenogenetic activation by ES or combined treatment with ES and DMAP or CHXM detrimentally affects the chromosome constitutions of porcine parthenotes during early embryonic development, leads to increased abnormal ploidy in the blastocyst stage.