Drosophila melanogaster 韓國 自然集團에 있어서 P-M system에 依據한 系統型 轉換

成耆昌,崔喜慶,金溶聲 성균관대학교 기초과학연구소 1989 論文集 Vol.40 No.1

Isofemale lines of Drosophila melanogaster were established from Daejon in Korea and were examined in order to investigate the changes of cytotype or strain type by P-M system through 1∼15 generations. The results are as follows: 1. Using π_2 (strong P) strains and bw;st (true M) strains as standard strains, the mean sterility frequencies from Cross A were 20.8%∼34.6% for each generations and the mean sterility frequencies from Cross B were 0.0%∼0.3%. 2. Frequency of strain with P cytotype for each generation was analyzed to be 44.8%(G₁), 59.2%(G₂), 43.7%(G₄), 36.7%(G_7), 29.2%(G_10) and 36.7%(G_15). Therefore it was tend to be low as increased with generation number, but the differencies in percentage of GD sterility between each generation are non-significant statistically. 3. Among the isofemale lines, type conversions were observed. Q→M', M'→Q and M'→M changes have occured with frequency of 18.4%, 8.2% and 4.1%, respectively. The remaining lines (69.3%) were unchanged through several generations. 4. The results suggest that Drosophila melanogaster are appeared temporally as a certain strain type in natural population, but the type conversions were represented by interactions between P elements in each genome and cytoplasm for each generation.

단어생성시 기능적 자기공명영상을 통한 운동 언어중추의 국소화

정상욱,김주용,송인찬,이경민,이상건,장기현 대한신경과학회 1998 대한신경과학회지 Vol.16 No.5

Mycosis Fungoides 1예 보고

지미경,양기화,김병기,심상인,김선무 大韓血液學會 1984 大韓血液學會誌 Vol.19 No.1

8.3% Carbamide Peroxide 함유 펜 형 자가미백제인 BIancTis Forte의 색조개선 및 안전성에 관한 임상연구

이진경,민선홍,홍성태,오소람,정신혜,황영혜,유성엽,배광식,백승호,이우철,손원준,금기연 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.2

This clinical study evaluated the whitening effect and safety of polymer based-pen type BlancTis Forte(NIBEC) containing 8.3% carbamide peroxide. Twenty volunteers used the BlancTis Forte whitening agent for 2 hours twice a day for 4 weeks As a control. Whitening Effect Pen (LG) containing 3% hydrogen peroxide was used by 20 volunteers using the same protocol. The change in shade (ΔE^(*) color difference) was measured using Shadepilot™ (DeguDent) before, during and after bleaching (2 weeks, 4 weeks and postbleaching 4 weeks). A clinical examination for any side effects (tooth hypersensitivity or soft tissue complications) was also performed at each check-up. The following results were obtained. 1 Both the experimental and control groups displayed a noticeable change in shade (ΔE) of over 2 No significant differences were found between the two group (p>0.05) implying that the two agents have a similar whitening effect. 2 The whitening effect was mainly due to changes in a and b values rather than in L value (brightness). The experimental group showed a significantly higher change in b value thus yellow shade than the control(p < 0.05) 3 None of the participants complained of tooth hypersensitivity or soft tissue complications confirming the safety of both whitening agents 8.3%의 carbamide peroxide를 함유한 펜형 코팅용 미백제인 BlancTis Forte (NIBEC, Seosul & JinCheon)를 실험군으로, 3% hydrogen peroxide를 함유한글 Whitening Effect Pen (LG. Seoul) 제재를 대조군으로 각각 피험자 20명에게 2시간씩 1일 2회 제조사의 지시대로 치아표면에 4주간 적용하도록 지시하고 색조개선 효능과 안전성을 평가하였다. 미백 효과는 미백 전 및 미백 2주, 4주 및 미백 종료 4주 후에 Shadopilot™을 이용하여 색 변화를 측정하였고, 매 내원시기마다 모든 환자는 치수생활력 검사와 치주 및 치태 검사를 통해 부작용 여부 (치아과민증 및 구감 내 연조직의 부작용)를 기록한 후 다음과 같은 결과를 얻었다. 1.실험군 및 대조군의 색 변화량 (ΔE)은 2이상으로 인지할 수 있는 색 변화를 보였으며, 두 제품 간에는 통계적으로 유의한 차이를 보이지 않아 (p > 0.05) 유사한 미백효능을 나타냄을 알 수 있었다. 2,미백효과는 명도의 개선보다는 주로 a. b값의 변화에 의한 것으로 특히 실험군에서 b값의 변화, 즉 황색조의 개선효과가 대조군에 비해 유의성 있게 높은 것으로 나타났다 (p <0.05). 3.치아나 치은의 과민증이나 이상증상을 호소하는 피험자는 없어 두 제품 모두 안전성을 확인할 수 있었다.

소아 백혈병의 혈청 철, 총 철결합능 Transferrin포화율 및 Ferritin치에 관한 연구

문경래,정은경,박상기 朝鮮大學校 附設 醫學硏究所 1991 The Medical Journal of Chosun University Vol.16 No.1

Author reviewed the clinical symtoms, hematological findings and serum Fe, total iron binding capadty(TIBC), transferrin saturation and levels of 40 children diagnosed as leukemia at the pediatric department of Chosun University hospital during a period of 7 years from Jan. 1983 to Dec. 1989. Also, 20 normal children as control group were studied. The results were summarized as follows: 1) The Mean±S.D. levels of the serum Fe, TIBC, transferrin saturation and ferrtin of leukemia 40 cases and control group were 126.8±37.8㎍/㎗, 276.1±37.8㎍/㎗, 47.1±15.6%, 244.5±52.7ng/㎖ and 107.2±34.2㎍/㎗, 309.9±31.8㎍/㎗, 34.7±11.4%, 69.6±30.8ng/㎖, respectively. The difference of the serum Fe levels between leukemia and normal control was statistically not significant (P>0.1) but the serum Fe, TIBC, transferrrin saturation and ferritin levels were significantly different(P<0.05, P<0.01, P<0.001). 2) The differences in the mean levels of the serum Fe, TIBC, transferrin saturation and ferfitin among the types of leukemia were not significant. 3) The differences of the serum TIBC, transferrin saturation and ferritin levels between leukemia and normal control were statistically significant. From the very high serum ferritin levels, it is thought that serum ferritinemia as tumor marker may be useful in diagnosis of leukemia.

면역학적 특성에 따른 yeast cytochrome c의 구조에 관한 연구

조경환,우기민,조만희,이상한,박현경,김창세 순천향의학연구소 2000 Journal of Soonchunhyang Medical Science Vol.6 No.2

The antiserum against yeast cytochrome c and horse heart cytochrome c was reacted immunologically with those from various species. The results were as followings; 1. The antiserum against horse heart cytochrome c was reacted immunologically with heart cytochrome c of horse, cow, rabbit, mouse, chicken, pigeon, frog, tuna, and guanaco, and were not with yeast and neurospora cytochrome c. 2. However, antiserum against yeast cytochrome c was only reacted immunologically with yeast cytochrome c, and was not mammals and vertebrates horse, cow, rabbit, mouse, chicken, pigeon, frog, tuna, guanaco, even neurospora 3. CNBr-digested peptides of horse heart cytochrome c were obtained 5 peaks, Ⅰ(1-80), Ⅱ(1-65), Ⅲ(66-104), Ⅳ(81-104), Ⅴ(66-80), and other peptide (1-50). Among them peptides Ⅰ and Ⅱ were weakly reacted immunologically with antiserum against horse heart cytochrome c. CNBr-digested peptides of horse heart cytochrome c were not reacted with antiserum against yeast cytochrome c. 4. From the above, the immunologically positive cross reaction was thought to be related with Ω loop D.

납착방법에 따른 임플란트 지지 보철물의 정확성

박상현,허진경,계기성 조선대학교 구강생물학연구소 2003 口腔生物學硏究 Vol.27 No.1

The Purpose of this study was to measure and compare the gap distance between implant fixture and implant framework fabricated by three techniques; (1) one-piece casting technique. (2) at the same time soldering technique after casting. (3) at the different time soldering technique after casting. Four 3i (diameter 4.0 ㎜) implant fixtures were fixed in the stone block. Implant bar framework was completed with type 111 gold alloys after it was waxed up with wax sleeve. Implant bar framework was soldered after it was cut with 0.2 ㎜ gap distance and fixed with pattern resin. Gap distances between each implant fixture and abutment, each gap distances were measured by means of stereomicroscope and micrometer ruler. The results were as follows : 1. In comparison of gap distance between implant fixture and abutment, one-piece casting technique group was 531 ㎛, soldering at the same time group was 250 ㎛,soldering at the different time group was 46 ㎛. Therefore, marginal adaptation of soldering technique group was higher than one-piece casting technique group. And marginal adaptation of soldering at the different time technique was higher than soldering at the same time technique. 2. In comparison of distance between abutment and abutment, one-piece casting technique group was 44.100 ㎜, soldering at the same time technique was 44.064 ㎜, soldering at the different time was 44.059 ㎜ and there were not significant differences.

인간의 혈장아포지단백 A-I에 특이성을 지닌 단일클론항체 A-I30의 light chain의 가변부위를 coding하는 cDNA의 클로님

이상한,우기민,조만희,장예진,김창세,김정경 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

I prepared a monoclonal antibody (mAb) A-l30 to HDL apolipoprotein A-l with the ultimate goals of expressing the valuable immunodiagnostic single-chain Fv (scFv) in Escherichia coli. The binding specificity of mAb A-l30 was determined by Western blot analysis. From the hybridoma cell line secreting mAb A-l30, poly(A)+ RNA was prepared and used as a template for cDNA synthesis and cloning. The nucleotide sequence analyses revealed that the variable regions of the heavy and light chains were members of mouse heavy chain subgroup ⅡA and κ light chain subgroup Ⅱ, respectively. Comparison of the nucleotide sequences with mouse immunoglobulin genes listed in the GenBank data base showed that the cDNAs have not been previously reported.

영아기 호흡기 질환의 이환요인에 관한 연구

신상원,김은영,노영일,양은석,문경래,박상기,박영봉 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

Purpose: Respiratory tract infections are common in the first year of life. Severity of respiratory tract infection in infants is associated with early-life environmental factors, In recent, genetic studies suggest a role of heredity in susceptibility to severe respiratory tract infection(RTI) in infants. We designed a case control study to further investigate relative importance of familial influence in risk of respiratory tract infection in infants compared to environmental factors. Methods: We selected 126 children(44 cases; 82 controls) that admitted or visited to Chosun University Hospital. Cases were infants under age 1 year admitted to hospital with severe respiratory tract infection. Familial history and other factors were recorded in cases and controls by questionnaire. Results: Out of 126 infants, Patients admitted with severe respiratory tract infection are 44 cases. Diagnosis of patients with RTI are acute bronchitis 15 cases(34.1%), pneumonia 12 cases (27.3%), acute nasopharyngitis 7 cases (15.9%), acute bronchiolitis 5 cases (11.4%), infantile asthma 3 cases (6.8%), and croup 2 cases (4.5%). The crude odd ratio of repiratory tract infection of parental smoking is 3.35 and cow mik feeding 3.13, Prematurity & low birth weight 2.39, maternal allergic disease 2.13, and child allergy 1.92. Conclusion: Maternal allergic disease, parental smoking, Prematurity and low birth weight, and Allergic diseases increased the risk of respiratory tract infection in infants. Breast milk feeding decreased that. These results support the possibility that genetic factors play an important role in susceptibility to recurrent and severe respiratory infections in early life.

학동기 비만아동의 피부두께의 통계적 관찰

김경석,나기찬,정은경,문경래,박상기,박영봉 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

The measurements of triceps skinfold thickness, body weight and height were done in children aged 7 to 12 years(3,142 boys and 2588 girls) in Kwangju in 1992. The author also observed degree of obesity, prevalence of obesity and average value of triceps skinfold thickness. The results were summarized as follows: 1) The mean value of triceps skinfold thickness acceding to age in male was 7 years 10.5mm, 8 years 10.5mm, 9 years 10.2mm, 10 years 12.3mm, 11 years 13.8mm, 12 years 12.3mm. In the female it was 7 years 11.9mm, 8 years 11.9mm, 9 years 11.6mm, 10 years 12.6mm, 11 years 14.1mm, 12 years 13.6mm. 2) The mean value of triceps skinfold thickness acceding to age in obese male was 7 years 16.3mm, 8 years 17.3mm, 9 years 16.0mm, 10 years 19.5mm, 11 years 23.7mm, 12 years 20.1mm. In the obese female it was 7 years 17.3mm, 8 years 17.9mm, 9 years 18.4mm, 10 years 19.5mm, 11 years 21.2mm, 12 years 20.3mm.