소매업의 유통정보시스템 구축 방안 연구

옥선종,이준우,김유오 한국유통정보학회 2000 유통정보학회지 Vol.3 No.2

The information-based age will emerge according to the advancement of the whole society, change from distribution revolution to distribution information revolution has a meaning to facilitate innovation. Such distribution revolution starting with a purpose to provide various goods and competitive price for customers when real mass production, consumption appeared, finally has got to cope with the age of great transition. Distribution of informationalization helps the effectiveness of the whole distribution system by creating information network using various information function, human resources at each stage from to manufacture industry based on customer information. This paper aims to check these conditions, attempt theoretical approaches through existing literature and precedent studies, review application cases currently introduced and enforced, and clarify the fundamental framework of distribution information system available at the distribution information system in our country using the cases of advanced distribution companies. Accordingly, it examined the basic system of bar code, POS and VAN/EDI to be basis in the construction of distribution information system, compared the construction plan through advanced distribution companies and reviewed its direction, furthermore investigated mainly its application system, SCM, ECR/QR and the direction of our country's distribution information system. The limitation of this paper lies with that correct verification in the introduction and utilization of enterprises' distribution system was not performed because it was carried out through consideration by literature. For the time to come, research will be continuously conducted taking into consideration the linkage of our country's distribution information system in growing stage with that of the advanced countries in stable stage.

대동맥 협착증과 동반된 출혈성 위장관 동정맥 기형에서 Estrogen-Progesterone 치료 1예

김도연,김화정,김효정,남준식,박수영,박영미,신정은,주미순,황민규,정혜경,손혜영,이선영,이한주 大韓消化器內視鏡學會 1999 Clinical Endoscopy Vol.19 No.부록2

review on the research of mechanical problems with different moduli in tension and compression

Jun-yi Sun,Hai-qiao Zhu,Shi-hong Qin,Da-lin Yang,Xiao-ting He 대한기계학회 2010 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.24 No.9

Most materials exhibit different tensile and compressive strains given the same stress applied in tension or compression. These materials are known as bimodular materials. An important model of bimodular materials is the criterion of positive-negative signs of principal stress proposed by Ambartsumyan. This model is mainly applicable to isotropic materials and deals with the principal stress state in a point. However, due to the inherent complexity of the constitutive relation, FEM based on iterative strategy and analytical methods based on a simplified mechanical model are required. In this paper, we review the basic assumptions of this model and its development, several innovative computational methods, and some important engineering applications. We also discuss the sequent key problems in this field.

A practical method for simultaneous determination of Poisson’s ratio and Young’s modulus of elasticity of thin films

Jun-yi Sun,Jian-li Hu,Zhou-lian Zheng,Xiao-ting He,Huan-huan Geng 대한기계학회 2011 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.25 No.12

In this paper, based on the exact analytical solution of axisymmetric deformation of the circular membrane fixed at its edge under the action of uniformly-distributed loads, we propose a new method to be able to simultaneously determine Poisson's ratio and Young's modulus of elasticity for thin films. We also present a set of exact formulas used for simultaneously determining Poisson's ratio and Young's modulus of elasticity for free-standing thin films or coating thin films without residual stresses or pre-tension. This method has the advantages of simplicity and reliability, and it doesn’t involve the substrate effect.

Power series solution of circular membrane under uniformly distributed loads: investigation into Hencky transformation

Jun-yi Sun,Yang Rong,Xiao-ting He,Xiao-wei Gao,Zhou-lian Zheng 국제구조공학회 2013 Structural Engineering and Mechanics, An Int'l Jou Vol.45 No.5

In this paper, the problem of axisymmetric deformation of the circular membrane fixed at its perimeter under the action of uniformly-distributed loads was resolved by exactly using power series method, and the solution of the problem was presented. An investigation into the so-called Hencky transformation was carried out, based on the solution presented here. The results obtained here indicate that the well-known Hencky solution is, without doubt, correct, but in the published papers the statement about its derivation is incorrect, and the so-called Hencky transformation is invalid and hence may not be extended to use as a general mathematical method.

S-benzyl-cysteine-mediated Cell Cycle Arrest and Apoptosis Involving Activation of Mitochondrial-dependent Caspase Cascade through the p53 Pathway in Human Gastric Cancer SGC-7901 Cells

Sun, Hua-Jun,Meng, Lin-Yi,Shen, Yang,Zhu, Yi-Zhun,Liu, Hong-Rui Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11

S-benzyl-cysteine (SBC) is a structural analog of S-allylcysteine (SAC), which is one of the major water-soluble compounds in aged garlic extract. In this study, anticancer activities and the underlying mechanisms of SBC action were investigated and compared these with those of SAC using human gastric cancer SGC-7901 cells. SBC significantly suppressed the survival rate of SGC-7901 cells in a concentration- and time-dependent manner, and the inhibitory activities of SBC were stronger than those of SAC. Flow cytometry revealed that SBC induced G2-phase arrest and apoptosis in SGC-7901 cells. Typical apoptotic morphological changes were observed by Hoechst 33258 dye assay. SBC-treatment dramatically induced the dissipation of mitochondrial membrane potential (${\Delta}{\Psi}m$), and enhanced the enzymatic activities of caspase-9 and caspase-3 whilst hardly affecting caspase-8 activity. Furthermore, Western blotting indicated that SBC-induced apoptosis was accompanied by up-regulation of the expression of p53, Bax and the down-regulation of Bcl-2. Taken together, this study suggested that SBC exerts cytotoxic activity involving activation of mitochondrial-dependent apoptosis through p53 and Bax/Bcl-2 pathways in human gastric cancer SGC-7901 cells.

Power series solution of circular membrane under uniformly distributed loads: investigation into Hencky transformation

Sun, Jun-Yi,Rong, Yang,He, Xiao-Ting,Gao, Xiao-Wei,Zheng, Zhou-Lian Techno-Press 2013 Structural Engineering and Mechanics, An Int'l Jou Vol.45 No.5

In this paper, the problem of axisymmetric deformation of the circular membrane fixed at its perimeter under the action of uniformly-distributed loads was resolved by exactly using power series method, and the solution of the problem was presented. An investigation into the so-called Hencky transformation was carried out, based on the solution presented here. The results obtained here indicate that the well-known Hencky solution is, without doubt, correct, but in the published papers the statement about its derivation is incorrect, and the so-called Hencky transformation is invalid and hence may not be extended to use as a general mathematical method.

소아 뇌졸중에서 간질 발생의 위험 요인

이준선(Jun Sun Yi),김영옥(Young Ok Kim),강지선(Byung Ju Kim),김병주(Ji Sun Kang),우영종(Young Jong Woo),김재휴(Jae-Hyu Kim) 대한소아신경학회 2002 대한소아신경학회지 Vol.10 No.1

목적:뇌졸중은 주로 성인에서 간질 발생의 주된 원인이나,소아기의 뇌졸중은 성인과는 달리 다양한 원인에 의하여 발생되며, 뇌졸중 후 간질 발생에 대한 연구는 별로 되어있지 않다. 본 연구에서는 소아기 뇌졸중 후 경련 및 간질 발생 빈도 및 위험요인에 대하여 조사하였다. 방법: 1987년부터 1999년까지 전남대학교 병원 소아과, 신경외과에서 뇌졸중으로 치료받은 환아들중 6개월 이상 추적관찰이 가능하였던 15세 미만의 환아 70명(남 39명, 여 31명)을 대상으로 하여 간질 발생의 유무 및 시기를 조사하였으며, 간질이 발생하였던 환아들에 대하여 뇌졸중의 원인질환과 CT, MRI로 병변의 위치 및 범위를 결정하여 위험요인들을 분석하였다. 결과: 70명 중 38명(54.3%)에서 간질이 발생하였으며 출혈성 뇌졸중의 원인으로는 동정맥기형(18명), 비타민 K 결핍증(7명), 혈우병(5명) 등이, 허혈성 뇌졸중의 원인으로는 특발성(15명), 모야모야병(11명), 편경련-편마비-간질증후군(6명) 등이 있었다. 출혈성 뇌졸중의 경우 45.7%(16/35명)에서, 허혈성 뇌졸중의 경우 62.9%(22/35명)에서 간질이 발생하였다. 대뇌 피질 침범 여부는 간질 발생에 영향을 미치지 않았으며, 대뇌 피질 중 측두엽에 병변이 동반된 경우 비교적 많은 간질이 발생하였다. 대뇌의 우측 반구에 병변이 있는 경우 42.3%(11/26명)에서 간질이 발생하였으나, 좌측 반구에 병변이 있는 경우에는 76.7%(23/30명)에서 간질이 발생하여 유의한 차이를 보였다. 단일 대뇌엽 병변시 47.1%(8/17명), 여러 대뇌엽 병변시 56.6%(30/53명)에서는 간질 발생을 보여 병변의 범위는 간질 발생에 큰 영향이 없었다. 초기 경련과 후기 경련은 모두 높은 간질 발생을 보였다. 결론:뇌졸중 후 간질은 다양한 원인 질환에 의해 발생하였으며 대뇌 좌측 반구 병변이 반대측보다 더 많은 간질 발생을 보였으며, 경련 발생유무가 간질 발생과 관련을 보였다. 대뇌피질 침범여부와 병변의 범위는 간질 발생률에 있어 차이를 보이지 않았다. PURPOSE: Post-stroke seizures and epilepsy were mainly studied in adults. Selected groups of children with stroke were studied to evaluate the incidence of seizures and epilepsy and the risk factors of epilepsy after stroke. METHODS: Seventy consecutive stroke children younger than 15 years of age were retrospectively reviewed to evaluate the incidence, times, causes of epilepsy and the risk factors epilepsy after stroke. The number and location of the lesion as imaged on the CT scan, and MRI scan were determined. RESULTS: Epilepsy after stroke was diagnosed in 38(54.3%) of 70 stroke patients:16 (45.7%) of 35 with hemorrhagic stroke and 22(62.9%) of 35 with ischemic stroke. Arteriovenous malformation(18), vitamin K deficiency(7), hemophilia(5) were frequent causes in hemorrhagic stroke, and idiopathic(15), moyamoya disease(11), hemiconvulsion-hemiplegia-epilepsy syndrome(6) were frequent in ischemic stroke. No statistically significant differences were noted with relation to sex, type of stroke, number of the lobar lesions, between cortical and subcortical lesions and onset time of initial seizure. Epilepsy developed more often in patients who had lesions located in the left cerebral hemisphere (76.7%) than on the right(42.3%)(P<0.01). CONCLUSION: Epilepsy developed more often in children who had lesion located in left cerebral hemisphere. No statistically significant differences noted in relation to sex, type of stroke, number of the lobar lesions and between cortical and subcortical lesions.

일반논문 : 근대 초 조선민족성 담론의 형성 배경과 논의 방식

이선이 ( Sun Yi Lee ),이준태 ( Jun Tae Lee ) 국제비교한국학회 2010 비교한국학 Comparative Korean Studies Vol.18 No.2

The Korea Cohort Consortium: The Future of Pooling Cohort Studies

Sang-Jun Lee,Kwang-Pil Ko,Jung Eun Lee,Inah Kim,Sun Ha Jee,Aesun Shin,Sun-Seog Kweon,Min-Ho Shin,Sangmin Park,Seungho Ryu,Sun Young Yang,Seung Ho Choi,Jeongseon Kim,Sang-Wook Yi,Daehee Kang,Keun-Young 대한예방의학회 2022 예방의학회지 Vol.55 No.5

Objectives: We introduced the cohort studies included in the Korean Cohort Consortium (KCC), focusing on large-scale cohort studies established in Korea with a prolonged follow-up period. Moreover, we also provided projections of the follow-up and estimates of the sample size that would be necessary for big-data analyses based on pooling established cohort studies, including population-based genomic studies. Methods: We mainly focused on the characteristics of individual cohort studies from the KCC. We developed “PROFAN”, a Shiny application for projecting the follow-up period to achieve a certain number of cases when pooling established cohort studies. As examples, we projected the follow-up periods for 5000 cases of gastric cancer, 2500 cases of prostate and breast cancer, and 500 cases of non-Hodgkin lymphoma. The sample sizes for sequencing-based analyses based on a 1:1 case-control study were also calculated. Results: The KCC consisted of 8 individual cohort studies, of which 3 were community-based and 5 were health screening-based cohorts. The population-based cohort studies were mainly organized by Korean government agencies and research institutes. The projected follow-up period was at least 10 years to achieve 5000 cases based on a cohort of 0.5 million participants. The mean of the minimum to maximum sample sizes for performing sequencing analyses was 5917-72 102. Conclusions: We propose an approach to establish a large-scale consortium based on the standardization and harmonization of existing cohort studies to obtain adequate statistical power with a sufficient sample size to analyze high-risk groups or rare cancer subtypes.