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      • 일반 경비지도사의 교육훈련체계와 만족도와의 관계

        최중철,권봉안,정순광 한국안전교육학회 2001 한국안전교육학회지 Vol.4 No.2

        The purpose of this article was to identify the training participants through the training status for security guard instructors. This study set 350 security guard instructors taking the basic training for security guard instructors located in Seoul as a population, and selected the sample using a cluster random sampling, the probability sampling method with the same probability including the individual factors if population. The survey instrument of this study was a questionnaire, which was prepared using the survey questionnaire regarding the Korea Civil Security Guard Training Commands presented by Kang, Gil-hoon(1998). The questionnaire was composed of 3 items on demographical characteristics, 30 items on training system, and 10 items on training satisfaction, and reliability between the total questionnaire items, Cronbach α was high as .90. Collected data was analyzed using the SPSS/PC Windows 10.0 statistical program. At first, in demographical characteristics, its satisfaction was examined through frequency analysis and average and standard deviation of remaining factors through mono-variable analysis and LSD, and correlation in the training program, program, assessment and method was analyzed, Based on the above research procedures and data analysis, following conclusion was obtained The training satisfaction according to demographical characteristics differed by age(.001), service term(.001) and study level(.001). The security guard instructors' satisfaction to curricula differed by age(.001), service term(.001) but did not differ by study level(.160). The security guard instructors' satisfaction to training programs by age(.001), but did not differ by service term(071), study level(.109). The security guard instructors' satisfaction to training assessment differed by age(.001), service term(.001) and study level(.001). The security guard instructors' satisfaction to training method differed by age(.001), service term(.001) and study level(.001).

      • 단결정 Si(111) 위에 형성된 Ti-실리사이드에 대한 RBS 및 XRD 분석

        이중환,권오준,최치규,박동수,김건호,이상환,이의완,곽호원 濟州大學校 基礎科學硏究所 1991 基礎科學硏究 Vol.4 No.1

        초고진공 상태에서 p형 Si(111)기판에 Ti을 증착한 후 고진공에서 열처리하여 Ti-실리사이드를 형성시켰으며, Ti-실리사이드의 상전이 및 형성운동학은 2 MeV⁴He? 이온 후방산란과 x-선 회절방법으로 규명하였다. 형성된 TiSi₂는 결정학적으로 C49(ZrSi₂)와 C54 구조의 두 종류로 확인되었다. C49 TiSi₂상은 열처리온도가 700℃이하의 저온에서 형성되었고, 700℃ 이상의 고온에서는 C54 TiSi₂상으로 나타났다. 본 연구에서 확인된 C54 TiSi₂전이온도(??)는 700℃ 였고, TiSi₂형성온도 영역내에서 TiSi₂ 층두께(χ)와 열처리시간(t)의 관계는 저온(700℃ 이하)일 경우 ??이고, 고온(750℃ 이상)에서는 χ=ct+d 의 관계식이 만족됨을 알 수 있었다. 이것은 700℃ 이하에서 TiSi₂ 형성기구가 Si 확산에 의해 제어되며, 750℃ 이상에서는 핵형성 제어에 의하여 계면반응하는 것으로 나타났다. Titanium silicides were prepared by depositing titanium film on p-type Si(111) followed by annealing in ultra high vacuum. The growth kinetics of Ti-silicide has been studied by using ion backscattering spectrometry and x-ray diffractometry. Two crystallographic structures of Ti-silicide were identified the (ZrSi₂)structure and C54. The C49 TiSi₂ phase was formed at low annealing temperature(<700℃),and it transformed to the C54 phase over 700℃. The relation between the thickness of TiSi₂ layer(χ) and the annealing time(t) was ?? when annealing temperature was under 700℃ and χ=ct+d when that was over 750℃. The former implied that the formation of TiSi₂ was controlled by diffusion and the latter by nucleation of at the Ti/Si(111) interface.

      • 栽培中 Tomato 果實의 窒酸鹽 및 亞窒酸鹽과 Ascorbic acid의 含量變化

        尹衡植,申大休,崔載春,權重浩 慶北大學校 1982 論文集 Vol.33 No.-

        This experiment was carried cut to investigate the relationship between nitrite and ascorbic acid contents in two kinds of tomato fruits namely, Bokwang, Suekwang, which were different distinguished in growth periods during culture. The results obtained were as follows. The nitrate content in two kinds of tomato fruits was relatively higher in Bokwang than Suekwang. It indicated high content as 5.8-12.5 ppm in flesh and 0.3-2.5 ppm in gelatinous pulp. In the beginning of growth period, nitrate content in flesh was 50-62.5ppm, and in the latter period was 21.3-38.4ppm. In the case of gelatinous pulp, it was decreased from 14.0-16.2ppm in the beginnig period to 9.3-10.7ppm in the latter period. In the case of nitite, there was no difference between two varieties. Nitrite content during growth increased from 0.15ppm to 0.21ppm in flesh and from 0.06ppm to 0.1ppm in gelatinous pulp. There was no difference between two varieties during growth in total ascorbic acid content and its concentration was 24.2-27.5mg in gelatinous pulp and was 13.8-18.6mg in flesh. The difference between two parts was about 10mg. In the changes of nitrate and nitrite content in tomato fruits, nitrate was decreased, whereas nitrite content was increased. In the changes of nitrate and ascorbic acid content in tomato fruits, nitrate content was decreased but that of ascorbic acid was increased slightly. In the changes of nitrite and ascorbic acid content in tomato fruits, nitrite content was increased and that of ascorbic acid was slightly increased too.

      • KCI등재

        성인의 급성 심장사에서 정상 심장례의 분석

        강신몽,이원태,이한영,서중석,최영식,권일훈,정낙은 大韓法醫學會 2000 대한법의학회지 Vol.24 No.2

        The authors analysed 53 cases of sudden cardiac death(SCD) without prominent structural abnormalies of heart out of witnessed 300 cases. Thirty four cases were associated with sleep and 19 with activity or rest. Twenty one cases were classified as having normal hearts, and the rest as structurally mild abnormal ones. Male was predominant, and almost of the victims were suffered in their twenties or thirties. All cases collapsed instantaneously or in very short time with various and not specific terminal symptoms. Inducing or trigger factors are not clarified in almost of the cases. Mechanisms or causes of death could not be defined clearly. We concluded that careful heart examination with detailed clinical history under the appropriate postmortem investigation system is only effective approach for the true mechanism and cause of death.

      • 감마선과 Methyl Bromide 처리가 사과의 생리화학적 품질에 미치는 영향

        강호진,정헌식,조덕조,변명우,최성진,최종욱,권중호 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2003 한국식품저장유통학회지 Vol.10 No.3

        감마선(0, 0.5, 1, 2, 3 kGy) 조사와 methyl bromide(MeBr, 26 g/㎏, 4hr) 훈증 및 이들의 처리시기가 사과의 생리화학적 품질특성에 영향을 비교하여, 검역처리를 위한 ◁그림 삽입▷ (원문을 참조하세요) 감마선 조사의 응용성을 검토하였다. 감마선과 MeBr 처리에 따른 사과의 생리화학적 품질평가에서 2kGy 이상의 감마선 조사와 MeBr 훈증은 사과의 일부 생리화학적 품질특성의 변화를 촉진시키는 것으로 나타났다. 감마선과 MeBr의 처리시기별로는 수확 직후보다는 저온(0℃)에서 40일 정도 보관 후 처리한 대체적으로 품질손상이 적은 것으로 나타났다. 따라서 1kGy 이하의 감마선 조사와 지연조사는 사과 과실의 품질을 비교적 양호한 상태로 유지할 수 있어 검역처리 기술로 활용성이 있는 것으로 생각된다. 'Fuji' apples were treated by gamma irradiation (0∼3 kGy) or methyl bromide fumigation at commercial conditions (MeBr, 25 g/㎏, 4 hr) for quarantine purpose at two different treatment timing after harvest and stored under air a 0℃ for 4 months. Associated with the treatment timing of irradiation or fumigation, after 40 days of storage at 0℃ following harvest was more adequate than immediately after harvest in keeping qualities of stored apples. However, more than 2 kGy irradiation and MeBr fumigation were detrimental to physiological and chemical qualities of the fruits. These results show that less than 1 kGy irradiation at the delayed timing has a possibility to be applied as a quarantine procedure without significant changes in the quality of apples.

      • SCIESCOPUSKCI등재

        Multiplex Analysis of Cytokines in the Serum and Cerebrospinal Fluid of Patients With Alzheimer's Disease by Color-Coded Bead Technology

        Choi, Chulhee,Jeong, Jee-Hyang,Jang, Joong Sik,Choi, Kyungsun,Lee, Jungsul,Kwon, Jongbum,Choi, Kyoung-Gyu,Lee, Jong-Seo,Kang, Sang Won 대한신경과학회 2008 Journal of Clinical Neurology Vol.4 No.2

        <P><B>Background and purpose</B></P><P>The availability and promise of effective treatments for neurodegenerative disorders are increasing the importance of early diagnosis. Having molecular and biochemical markers of Alzheimer's disease (AD) would complement clinical approaches, and further the goals of early and accurate diagnosis. Combining multiple biomarkers in evaluations significantly increases the sensitivity and specificity of the biochemical tests.</P><P><B>Methods</B></P><P>In this study, we used color-coded bead-based Luminex technology to test the potential of using chemokines and cytokines as biochemical markers of AD. We measured the levels of 22 chemokines and cytokines in the serum and cerebrospinal fluid (CSF) of 32 <I>de novo</I> patients (13 controls, 11 AD, and 8 Parkinson's disease [PD]).</P><P><B>Results</B></P><P>MCP-1 was the only cytokine detectable in CSF, and its levels did not differ between control and disease groups. However, the serum concentration of eotaxin was significantly higher in AD patients than in the control group.</P><P><B>Conclusions</B></P><P>The analysis of multiple inflammatory mediators revealed marginal differences in their CSF and serum concentrations for the differential diagnosis of AD and PD. These results provide evidence that immunological responses are not major contributors to the pathogenesis of AD and PD.</P>

      • SCOPUSKCI등재

        Pulmonary Langerhans Cell Histiocytosis in an Adult Male Presenting with Central Diabetes Insipidus and Diabetes Mellitus: A Case Report

        Choi, Yeun Seoung,Lim, Jung Soo,Kwon, Woocheol,Jung, Soon-Hee,Park, Il Hwan,Lee, Myoung Kyu,Lee, Won Yeon,Yong, Suk Joong,Lee, Seok Jeong,Jung, Ye-Ryung,Choi, Jiwon,Choi, Ji Sun,Jeong, Joon Taek,Yoo, The Korean Academy of Tuberculosis and Respiratory 2015 Tuberculosis and Respiratory Diseases Vol.78 No.4

        Pulmonary Langerhans cell histiocytosis is an uncommon diffuse cystic lung disease in adults. In rare cases, it can involve extrapulmonary organs and lead to endocrine abnormalities such as central diabetes insipidus. A 42-year-old man presented with polyphagia and polydipsia, as well as a dry cough and dyspnea on exertion. Magnetic resonance imaging of the hypothalamic-pituitary system failed to show the posterior pituitary, which is a typical finding in patients with central diabetes insipidus. This condition was confirmed by a water deprivation test, and the patient was also found to have type 2 diabetes mellitus. Computed tomographic scanning of the lungs revealed multiple, irregularly shaped cystic lesions and small nodules bilaterally, with sparing of the costophrenic angles. Lung biopsy through video-assisted thoracoscopic surgery revealed pulmonary Langerhans cell histiocytosis. On a follow-up visit, only 1 year after the patient had quit smoking, clinical and radiological improvement was significant. Here, we report an uncommon case of pulmonary Langerhans cell histiocytosis that simultaneously presented with diabetes insipidus and diabetes mellitus.

      • SCOPUSKCI등재

        Synthesis of Perhydroisoquinoline Ring Systems by N-Acyliminium Cyclization$^\sharp$

        Choi, Joong-Kwon,Jung, Young-Shik,Park, No-Sang Korean Chemical Society 1988 Bulletin of the Korean Chemical Society Vol.9 No.3

        The stereochemistry of N-acyliminium cyclizations to form decahydropyrrolo[2,1-a]isoquinolin-3(2H)-ones was studied. Particular attention was paid to the stereocontrol by an acetoxy group present on pyrrolidone ring. Two of the three new chiral centers were formed stereospecifically, and the third was controlled by elimination-hydrogenation sequence.

      • SCISCIESCOPUS

        Schisandrin A suppresses lipopolysaccharide-induced inflammation and oxidative stress in RAW 264.7 macrophages by suppressing the NF-κB, MAPKs and PI3K/Akt pathways and activating Nrf2/HO-1 signaling

        Kwon, Da Hye,Cha, Hee-Jae,Choi, Eun Ok,Leem, Sun-Hee,Kim, Gi-Young,Moon, Sung-Kwon,Chang, Young-Chae,Yun, Seok-Joong,Hwang, Hye Jin,Kim, Byung Woo,Kim, Wun-Jae,Choi, Yung Hyun UNKNOWN 2018 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol.41 No.1

        <P>Schisandrin A is a bioactive lignan occurring in the fruits of plants of the <I>Schisandra</I> genus that have traditionally been used in Korea for treating various inflammatory diseases. Although the anti-inflammatory and antioxidant effects of lignan analogues similar to schisandrin A have been reported, the underlying molecular mechanisms have remained elusive. In the present study, schisandrin A significantly suppressed the lipopolysaccharide (LPS)-induced production of the key pro-inflammatory mediators nitric oxide (NO) and prostaglandin E<SUB>2</SUB> by suppressing the expression of inducible NO synthase and cyclooxygenase-2 at the mRNA and protein levels in RAW 264.7 macrophages. Furthermore, schisandrin A was demonstrated to reduce the LPS-induced secretion of pro-inflammatory cytokines, including tumor necrosis factor-α and interleukin-1β; this was accompanied by a simultaneous decrease in the respective mRNA and protein levels in the macrophages. In addition, the LPS- induced translocation of nuclear factor-κB (NF-κB), as well as activation of mitogen-activated protein kinases (MAPKs) and phosphatidylinositol-3 kinase (PI3K)/Akt pathways were inhibited by schisandrin A. Furthermore, schisandrin A significantly diminished the LPS-stimulated accumulation of intracellular reactive oxygen species, and effectively enhanced the expression of NF erythroid 2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1). These results suggested that schisandrin A has a protective effect against LPS-induced inflammatory and oxidative responses in RAW 264.7 cells by inhibiting the NF-κB, MAPK and PI3K/Akt pathways; these effects are mediated, at least in part, by the activation of the Nrf2/HO-1 pathway. Based on these results, it is concluded that schisandrin A may have therapeutic potential for treating inflammatory and oxidative disorders caused by over-activation of macrophages.</P>

      • SCOPUSKCI등재

        Chemistry of 1-Methoxypyrrole-2-carboxylic Acid

        Joong-Kwon Choi,Young-Kil Chang,No-Sang Park,Kim Wan Joo Korean Chemical Society 1989 Bulletin of the Korean Chemical Society Vol.10 No.6

        1-Methoxypyrrole-2-carboxylic acid and its derivatives were prepared. Fridel-Crafts bromination occurs first at 4-position and then at 5-position. Acylation of 3-methyl derivative was also directed to 4-position.

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