최근 10년간 원광의대병원에서 시행한 소아 심장혈관 수술의 임상적 고찰

윤향석,정수미,최두영,오광수,오연균,김종덕,양현웅,이삼윤,김형곤,최종범,최순호,노병석 圓光大學校 醫科學硏究所 1995 圓光醫科學 Vol.11 No.2

We reviewed 10 years experiences of the clinical aspects and early postoperative results in 544 pediatric patients(age less than 16 years old). Among them. 529 cases had the congenital heart diseases, and 15 had the acquired diseases. Open heart surgery was performed in 413 patients. 115 cases were treated with non-open heart surgery. 16 with interventional catheterization. Annual increase of the cardiac patients was not significant in recent 10 years, except slight increase in 1994. The mean age of the study patients had been evidently changed to younger year by year. Total mortality rate of the open heart surgery was 6.4%. The cyanotic congenital heart diseases were high in early postoperative mortality by 25.7%, whereas 4% in acyanotic group. The age group less than one month was most highest in surgical mortality(66.7%). There were no deaths in patients with patent ductus arteriosus(103 cases), atrial septal defect(83 cases) or pulmonary stenosis(17 cases). Among 220 patients with ventricular septal defects(VSD). 10(4.5%) were died early postoperatively. In cyanotic group, the patients with pulmonary atresia with ventricular septal defects(PAVSD), transposition of the great arteries(TGA), interrupted aortic arch(IAA), complex cardiac anomalies with isomerism seemed to be most susceptible to an early death.

원위 대퇴골의 고립성 골연골종에서 발생한 속발성 연골 육종 1례 보고

정필현,황장수,강석,김용민,오형호,채동주,김종필 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

연골육종은 비교적 서서히 자라며 늦게 전이하는 악성 연골 종양으로 알려져 있다. 골 연골종에서 발생한 속발성 연골육종은 발생빈도는 드물며 타부위로의 전이가 적고 악성도가 낮은 경우가 많아 적합한 수술적 치료로서 좋은 예후를 보이는 것으로 보고되고 있다. 본 동국대학교 정형외과학 교실에서는 우측 대퇴골 원위부 골간단부에 생긴 고립성 골 연골종에서 이차적으로 발생한 연골육종을 치험한 바 문헌고찰과 함께 보고하는 바이다. A case of Secondary Chondrosarcoma Arising from Solitary Osteochondroma of the Distal Femur Department of Orthopaedic Surgery, College of Medicine, DongGuk University Phil Hyun Chung M.D., Jung Su Hwang M.D., Suk Kang M.D., Yang Mln Kim M.D., Hyung Ho Oh M.D., Dong Ju Chae M.D., Jong Pil Kim M.D. Chondrpsarcoma is a malignant cartilage-forming tumor that grows slowly and metastasis of this tumor occurs in late stage. Secondary chondrosarcomas arising from a solitary osteocartilaginous exostosis are rare and those have a better prognosis than other chondrosarcomas, and they rarely metastasize. We present our experience with a case of secondary chondrpsarcoma arising in solitary osteochondroma of distal metaphysis of right femur with clinical details.

Streptococcus oralis 의 인공치태 억제효과에 대한 연구

오종석,정성수,양규호,김선미 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.1

이 연구는 치아우식증이 주요 원인균인 Streptococcus mutans의 치태형성과 증식에 대한 Streptococcus oralis의 영향을 조사하고자 하였다. 이를 위해 S.mutans와 S.oralis 혼합 배양후 형성된 치태 무게와 생균수를 측정비교하였다. 또한 치태형성과 생균수에 영향을 미치는 요소들에 대해 조사하여 다음과 같은 결과를 얻었다. 1. S.mutans와 S.oralis의 혼합배양시 S.mutans 단독배양에 비해 치태무게와 생균수가 감소되었다. 2. S.mutans 단독배양에 10 mM의 표도당을 첨가한 군은 첨가하지 않은 군보다 치태무게가 증가되었으나,S.mutans와 S.oralis의 혼합배양에 10 mM의 포도당을 첨가한 군은 첨가하지 않은 군과 차이가 없었다. 3. S.mutans 단독배양에 10 mM S.mutans와 S.oralis 10 mM의 과당을 첨가한 군도 첨가하지 않은 군보다 치태무게가 증가되었다. 4. S.mutans와 S.oralis의 혼합농도를 달리하여 배양했을때 S.oralis의 혼합농도가 높아질수록 치태무게와 생균수는 감소되었다. 5. 배양기산(6,9,12,15시간)에 따른 치태무게와 생균수는 S.mutans단독배양에 비해 S.mutans와 S.oralis혼합배양시 배양 12시간 이후 급격히 감소되었다. 6. S.mutans와 S.oralis의 혼합배양에 H₂O₂를 소비하는 Staphylococcus epidermidis를 첨가한 군은 첨가히자 않은 군보다 치태무게와 생균수가 증가되었다. 이상의 결과로 S.oralis는 S.mutans와 혼합배양시 S.mutans의 증식과 인공치태의 생성을 억제함을 알 수 있었고, 이는 S.oralis가 H₂O₂를 분비함으로써 얻어진 결과임이 시사되었다. This study was performed to evaluate the effect of Streptococcus oralis on the formation of artificial plaque and the replication of Streptococcus mutans.S.mutans was incubated alone and in the combination with S.oralis in the beaker with wires. The produced plaque weight and the viable cells of S.mutans were compared between those cultures. Various factors were studied about the effect on the formation of plaque and the replication of S.mutans. Followings are the results. 1. Lower amount of plaque was produced and fewer cells of S. mutans were replicated at the mixed culture of S. mutans and S. oralis than S. mutans alone. 2. When 10 mM glucose was added, the plaque weight was increased in the culture of S. mutans alone. But in the mixed culture of S. mutans and S. oralis, the plaque weight was not increased when 10mM of glucose was added. 3. When 10 mM fructose was added, the plaque weight was increased in culture of S. mutans alone or combined S. mutans and S. oralis. 4. In the mixed culture of S.mutans and S. oralis with different concentration, the more S.oralis exist, the less plaque and the fewer viable cells of S. mutans were observed. 5. The plaque weight and the viable cells of S.mutans were more decreased in the mixed culture of S. mutans and S. oralis than S. mutans alone after 12 hours. 6. When Staphylococcus epidermidis consuming hydrogen peroxide was added to the mixed culture of S. mutans and S. oralis, the plaque weight and the viable cells of S. mutans were increased. These results indicate that S. oralis inhibited the formation of plaque and the replication of S. mutans,and this may result from the formation of hydrogen peroxide by S. oralis.

해조류에서 추출한 SCH-T3의 elastase 억제

오경석,박영립,이종석,황규왕,염윤기 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

Background & Objective: Upon UV irradiation of skin, matrix metalloproteinases are induced and then degrade collagen and elastin which provide the structural integrity of skin. The purpose of this study is to investigate the inhibition of elastase by SCH-T3 extracted from marine plants. Method: From gathered seaweeds, which are Laminariacea and Alariaceae in Phaeophyta, In Korea water, 21 materials were extracted. To determine the optimal condition for the extraction of SCH-T3, the yields of SCH-T3 was measured compared at various solvents, concentrations, and extraction time. Finally, the inhibitory effect of SCH-T3 on elastase was measured under various conentrations of SCH-T3. Results: Among 21 extracts, SCH-T3 had excellent elastase inhibitory effect. The yields of SCH-T3 was highest with the use of 60% and 70% ethanol as sovents, at 12 hours extraction, and with increasing temperature. Conclusion: These results suggest that SCH-T3, extracted from marine plants, has an inhibitory effect on elastase in vitro and may be used in prevention and treatment of photoaging in the future.

Fusobacterium nucleatum의 유황화합물 생성에 영향을 미치는 인자

오인근,박은혜,양규호,오종석 전남대학교 치의학연구소 2003 구강과학 Vol.15 No.1

Fusobacterium nucleatum, one of the bacteria causing halitosis, produces the volatile sulfur compounds (VSC) such as H2S in the media containing sulfur components, and forms FeS by binding with iron component. The various factors of oral cavity affect the concentration of sulfur compounds produced by Fusobacterium nucleatum. In this study, the effect of nutrients and pH on the production of sulfur compounds by Fusobacterium nucleatum was studied with the following results; 1. The optical density of broth was increased to 0.817±0.032 and 1.297±0.024 by adding 1.0% sodium thiosulfate and 0.05% L-cysteine hydrochloride in the media, respectively. 2. Though the optical density of broth was 0.799 ± 0.032 by adding volatile sulfur compounds (VSC) only in the media, it was increased to 1.775±0.003 and 1.648±0.022 by adding xylitol combined with glucose and fructose, respectively. 3. The concentration of VSC was above 20,000 ppb in the media above pH 5.5. The optical density of broth was still high in the media with L-cysteine hydrochloride of higher concentration, being low in the media of lower pH. 4. The concentration of VSC was high when there was distilled water or saline solution on the media, and their amount was small. These results suggest that the production of sulfur compounds by Fusobacterium nucleatum is inhibited by xylitol and acid.

釜山地域 經濟發展을 위한 地域企業人의 役割과 責任 : 企業家精神과 地域的 責任을 中心으로

오종석,황한식,김종관 부산대학교 1995 地域經濟硏究 Vol.- No.4

한국경제는 지금까지 국가 중심적 경제체제를 유지해 왔으나, 세계화, 지방화라는 시대적 변화에 직면하여 지역 분권적 경제체제를 확립하고, 이를 통해서 지역경쟁력을 강화함으로서 지역중심의 세계화를 추진해 나가지 않을 수 없게 되었다. 따라서 본 연구는 효과적인 지역경제발전을 모색해 나가기 위해서 부산지역을 연구대상으로 하여, 지역경제발전의 주체와 지역경제발전의 원동력을 조명하고, 지역경제발전을 위해서는 어떠한 환경이 조성되어야 하는 지를 문헌연구와 실증연구를 토대로 하여 고찰해 보고자 하였다. 그 결과, 다음과 같은 결론을 도출할 수 있었다. 첫째, 세계화, 지방화 시대의 지역경제 발전전략은 자립적·내발적 이어야 하며, 지역 스스로가 발전주체가 되어야 한다는 점이다. 특히 지역기업인은 지역에서 가장 중심적인 역할을 담담해야 하며, 지역기업 중심의 지역주체성 확립이 지역경제 발전의 기반이 되어야 한다는 것이다. 둘째, 지역경제 발전의 원동력은 지역기업인의 기업가정신과 지역적 책임이며, 이것을 통해 기업의 내생력을 강화시켜서 기업발전을 이룩하고, 지역경제의 발전을 실현해 나가야 한다는 점이다. 셋째, 지역경제의 발전을 위해서는 지역경제의 낙후원인을 분석, 진단하고 이를 통해서 외생적 환경조건을 정비함으로써 지역경제의 발전을 도모해 나가야 한다는 것이다.

현행 고등학교 화학 교과서 비교 연구

오제직,최석남,이종길 공주대학교 사범대학 과학교육연구소 1994 과학교육연구 Vol.25 No.1

This paper aims to help the teachers select the textbook and provide them with the basic teaching materials as an ideal model by analyzing the organization (its element and appropriateness), volume amount, experiment matter, and the contents of the highschool chemistry textbooks, which have been revised in accordance with the 5th amended curriculum. The results of the analogy are as follow 1. Organization (its element and appropriateness) : Though having some distincitive characteristics, all the textbooks have almost the same introduction, development, summary, and further study, which are appropriate for the textbook model. 2. The volume amount: All the textbooks have almost the same frame, but s a big difference in such things as the number of pages, of pictures and charts, of Gothic terminology, and relative importance of each chapter. And all the materials such as pictures and photos are black-and-white, which we think are less helpful to the students` study. 3. The experiment matter: There`s a geat difference in the number, kinds, ratio contents and subject of experiment in each chapter. And there are some distinctive characteristics in the type, level, method, and investigative skills of the experiments. 4. The contents : There are considerable differences in the additional and reduced sections. Therefore, which book is selected is very important, and the teachers should not skip any class-work.

치태형성 억제세균의 분리

오종석,박진경,양규호,정진 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.3

치태의 주요성분인 비수용성 글루캔의 형성을 억제시키는 세균을 분리하기 위하여 유치원 원아 만여명으로 부터 타액을 채취하였다.일회용 큐벧을 사용하여 비수용성 글루캔의 형성을 억제시킨 세균을 분리하였다.분리된 세균을 그람 염색과 API 20S kit 와 API 50 CHL kit를 사용하여 당발효 및 생화확적 특성을 검사한 결과,Streptococcus oralis,Streptococcus mitis,Streptococcus mitior,Streptococcus sanguis,Enterococcus durans,Lactobacillus lactis로 동정되었다.비수용성 글루캔 형성 억제 정도를 판정하기 위하여 일회용 큐벧에서 S.mutans 단독 배양시에는 550nm에서의 흡광도가 1.503이었으나,S.mutans 와 Streptococcus oralis,Streptococcus mitis,Streptococcus mitior,Streptococcus sanguis,Enterococcus durans,Lactobacillus lactis, Lactobacillus acidophilus 혼합 배양시에는 각각의 흡광도가 0.823,0.912,0.894,0.878,0.753,0.845,1.021로 감소되었다. The insoluble glucan is the major substance of dental plaque. In order to isolate the bacteria inhibiting the formation of insoluble glucan in disposable cuvette,saliva was got from about 10 thousand children.The isolated bacteria were tested by API 20S kit and API 50 CHL kit.These bacteria were identified as Streptococcus oralis,Streptococcus mitis,Streptococcus mitior,Streptococcus sanguis,Enterococcus durans,Lactobacillus lactis,and Lactobacillus acidophilus.When Streptococcus mutans was cultured with Streptococcus oralis,Streptococcus mitis,Streptococcus mitior,Streptococcus sanguis,Enterococcus durans,Lactobacillus lactis,and Lactobacillus acidophilus in disposable cuvette,the optical density at 550 nm was 0.823,0.912,0.894,0.878,0.753,0.845,1.021 respectively,while being 1.503 in the disposable cuvette Streptococcus mutans only.

韓·中 企業會計制度의 比較硏究 : 중국기업회계제도의 특성을 중심으로

吳鍾錫 대불대학교 1998 論文集 Vol.4 No.1

The reforms launched by Deng Xiaoping two decades ago had a great impact on the Chinese economic system and the accounting system has also changed very rapidly in this period. This paper aims to compare Chinese accounting standards with Korean and provide a finantial analysis framework for Korean investers to China. In accordance with "The Accounting Law of the People's Republic of China", the Chinese accounting standards are formulated to meet the needs of a socialist market economy, to standardize accounting practice and to ensure the quality of accounting information. Since 1990, Korean companies have invested in China for their business globalization, but are face with many problems such as tax, profit return and joint-venture contract dispute etc. Therefore, we need to understand Chinese accounting and its practice but there are many differences in terminology and classification of accounts with its Chinese characteristics. In conclusion, the harmonization of accounting standards in Korea and China will contribute to the Korea-Chinese economic cooperations and the development of international accounting standards.

유산구균 1370의 수용성 글루캔 형성에 영향을 미치는 인자

오인근,양규호,오종석 전남대학교 치과대학 2000 전남치대논문집 Vol.12 No.1

The water-soluble glucan prodeced by Lactococcus lactis 1370 affects the formation of dental plaque by Streptococcus mutans. In this study the factors affecting the formation of water-soluble glucan were assessed as the optical density of culture supernatant of Lactococcus lactis 1370 in the spectrophotometer. 1. The optical density of culture supernatant was high when Lactococcus lactis 1370 was cultured in M17 broth with 5% sucrose, while being low in culture supernatant of Streptococcus mutans. 2. The optical density of culture supernatant was higher when Lactococcus lactis 1370 was cultured in M17 broth with 10% sucrose than when being cultured without sucrose (p<0.05), and was higher at pH 7 than pH 5 (p<0.05). 3. The optical density of culture supernatant was the highest at 37℃ among 32℃, 37℃ and 42℃, and was higher in the anaerobic incubator than in the aerobic incubator (p<0.05). 4. The optical density of culture supernatant was the highest in the media containing 1.0mM CaCl2 (p<0.05), 2.5mM KCl (p<0.05), and 1.6 mM MgCl2. 5. When Streptococcus mutans was cultured in the media containing a quarter culture supernatant of Lactococcus lactis 1370 grown in M17 broth, the mean weight of produced artificial plaque was 103.0 mg on the wire, whereas being significantly reduced to 5.6mg in the media containing a quarter culture supernatant of Lactococcus lactis 1370 grown in M17 broth containing 5% sucrose (p<0.05). These results indicate that the water-soluble glucan is more formed by Lactococcus lactis 1370 in the media containing sucrose or under the adequate conditions for the growth of bacteria, and inhibits the formation of artificial plaque by Streptococcus mutans.