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      • 양극성장애와 새로운 항경련제의 효과

        남범우,서정석,정헌종,최진영 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.13 No.-

        Bipolar disorder, like epilepsy and migraine, is episodic in nature and psychiatric illness requiring lifelong treatment. So, it should not be surprising that anticonvulsants such as carbamazepine and valproate have proven efficacy as mood stabilizers. The newer anticonvulsants such as lamotrigine, gabapentin, topiramate, oxcarbazepine, tiagabine, and zonisamide may also be effective treatments for bipolar disorder. Identifying an anticonvulsant for use in bipolar disorder should take into account not only the pathophysiology of bipolar disorder but also the mechanism of action of the anticonvulsant. Evidence for effectiveness of these novel antiepileptic drugs in treating acute mania and depression as well as in preventing the recurrence of mania and depression is reviewed. In conclusion, although the novel anticonvulsants appear to be clinically useful, more controlled trials are needed to assess the effectiveness in bipolar disorder.

      • 백금 담지 카본블랙 촉매 제조 및 활성조사

        김종범,이무성,이완진,양갑승,서곤,김종호 全南大學校 觸媒硏究所 2002 觸媒硏究 論文集 Vol.23 No.-

        Platinum catalysts supported on carbon were prepared by using various method. The particle size distribution of loaded platinum was examined using transmission electron microscope, and that was discussed relatively to the oxidation treatment of carbon black and loading method of platinum. In addition, the relationship between its particle size distribution and catalytic activities in the deep oxidation reaction of carbon monoxide and the reduction removal of dissolved oxygen by hydrazine. The number of functional groups on carbon black largely increased by the oxidation treatment with nitric acid compared to that with air or hydrogen peroxide. The large number of functional groups were effective for homogeneous loading of platium, dispersing highly homogeneous platinum particles of 2∼3 nm in a diameter by the methanol reduction method. On the other hand, a large amount of platinum could be loaded on carbon balck using an impregnation method, but the particle size distribution of platinum was poor in homogeneity. Platinum could be dispersed with extremely small particles using on ion exchange method, but the loading amount of platinum was very small. The activities of Pt/VX catalysts in the oxidation reaction of carbon monoxide and the redution of dissolved oxygen strongly varied with the number of platinum atoms exposed, regardless of the particle size, indicating that the highest catalytic activity was obtained on the Pt/VX catalyst prepared using the methanol reduction method due to the high dispersion and large loading of platinum.

      • KCI등재후보

        외안각 절제술과 경결막 절개에 의한 안와 접근법

        정종철,김성범,서지훈,송민석,전창훈,최세훈,김현민 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.4

        Various surgical approaches to the orbits have been used. But the transconjunctival approach, also called the inferior fornix incision, provides adequate access to the orbital floor with esthetic results. Additionally, transconjunctival approach with lateral canthotomy allows more wide surgical field and good access to the orbital area. Generally, preseptal approach is more used rather than postseptal approach in the transconjunctival incision for the prevention of fat herniation during surgery. There are some complications in transconjunctival approaches but these complications can be prevented with careful surgical techniques. We report clinical results in 12 patients who were treated by preseptal transconjunctival incision with lateral canthotomoy for the treatment of orbital trauma. We were satisfied with this technique for reduction and reconstruction of the orbital trauma and we could also observe relatively good esthetic results.

      • KCI등재

        하악골에 발생된 Low grade 골육종:증례보고

        조현이,정종철,김호성,최재욱,성대경,서지훈,김성범,이계혁 大韓顎顔面成形再建外科學會 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.1

        Osteosarcoma is a primary malignant tumor arising most often in the long bone, but rare in jaw bone. Especially osteogenic sarcoma of the mandible is a rare tumor, comprising less than 0.5% of all head and neck tumors. Osteosarcoma occurs cheifly in young persons, and presenting very survival rates. Histopathologically this tumor can be classified three types, osteoblastic, fibroblastic, chondroblastic and classified from low grade to high grade by anaplasia or mitosis of the tumor cells. Sometimes, the exact diagnosis of osteosarcoma is difficult especially in low grade osteosarcoma, even if clinical or radiographical findings suggest to osteosarcoma. So suspcious to malignant bone tumor in clinical or radiological findings, biopsy should be taked from deep portion and multiple area, and sharing the patient history and radiographs with pathologist will assist in the development of the diagnosis. We report a case of low grade osteosarcoma on the mandible initially difficulty in accurate diagnosis. The patient visited our hospital for routine dental treatment but radiographic findings displayed ill-defined radiolucency with osteoid formation on the mandible. Final diagnosis was difficulty in initial biopsy but subsequent biopsy taked from deep portion presented infiltrative growth and mitosis of the tumor cell in some area with small osteoid bone formation, so we could reach final diagnosis as low grade sarcoma. We treated this patient with bloc resection of the mandible and immediate reconstruction with iliac corticocancellous block.

      • 제주도 연안 정치망 조업시스템 개발에 관한 연구 : 낙망에 의한 조업시스템 생력화 Studies for the Man Power Saving of Fishing System by Pound net

        김병엽,김석종,이창헌,김종범,서두옥 濟州大學校 海洋硏究所 2002 해양과환경연구소 연구논문집 Vol.26 No.-

        제주도 연안 정치망의 조업시스템 생력화와 실용화를 목적으로 어군의 도피를 최대한 방지하고 양망작업이 용이하도록 개량 설계된 낙망어구를 제주도 북제주군 한경면 금등정치망 어장에 부설하고 실용화 및 조업시스템 생력화에 대하여 현장실험을 실시하였는데 그 결과를 요약하면 다음과 같다. 1. 낙망어구규모에 적합한 조업선을 기계화하여 1척의 어선으로 조업이 가능하였다. 2. 조업어선 선수미부 양망현에 양망기인 캡스턴을 설치하므로 조업인원 2∼3명으로도 양망작업이 가능하였다. 3. 망갈이 작업시 양망한 그물을 선상에서 적재하고 육상에서 양륙할 때 파워블록을 사용함으로써 작업효율을 높일 수 있었다. In order to obtain the fundamental data for the man power saving and the practical use of fishing system for a set net in the coast of Jeju island, a pound net designed for making hauling operation easier and preventing a school of fish from escaping was set up at a fishing ground in Geumdeung and a field experiment was carried out. The fishing operation was feasible with one boat mechanized for the pound net and the hauling operation was not made possible with 2-3 persons till a net haular, that is, a capstan was set up on the hauling side of the boat. In addition, a power block enhanced the efficiency of operation for hauling up the net on board or hauling down on land.

      • 식이 상태와 카페인 투여가 일회적 운동 시 흰쥐 가자미근의 제 4형 당수송체에 미치는 영향

        김광찬,김종오,오명진,윤재석,서태범,윤진환,정일규 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

        The purpose of this study was to evaluate the effects of diet condition and caffeine ingestion prior to long distance treadmill running on the GLUT-4 protein expression in Sprague-Dawley rats' soleus muscle. Total is rats were used For subjects and assigned to six groups: Fasting control(FaC group), feeding control(FeC), asting+exercise(FaE), feeding +exercise(FeE), Fasting +caffeine+exercise(FaCE), and Feeding+caffeine+exercise(FeCE). Each animal belongs to fasting group was forced to be in fasting state at least for 14 hours, The food was provided to each rat in feeding group 12minutes prior to treadmill running and the caffeine was ingested through the stainless steel tube 60minutes prior to exercise. All rats in exercise groups were forced to perform treadmill running for B9 minutes at the speed of 18m/min, and 0%grade, immediately after exercise, all animal was anesthetized by Chlorofolm (DC Chemical, Co, Ltd) and about 10ml of blood was drawn from each animal's heart and than soleus muscle was exposed and separated from the rat's leg. we found that the GLUT-4 in feeding groups increased much significantly compared to fasting groups(p<.05). The exercise in fasting state appeared to suppress the expression of GLUT-4 protein different from the exercise in feeding state. Cafreine ingestion prior to treadmill running of 60 minutes induced the significant increase or GLUT-4 protein expression both in fasting or feeding states.

      • 공복 시 Caffeine 투여 후 일회성 운동이 흰쥐의 인슐린 및 골격근의 GLUT-4 발현에 미치는 영향

        정일규,오명진,김영표,김종오,윤재석,서태범,윤진환 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.5

        This study was done to investigate the effects of caffeine ingestion on the expression of GLUT-4 in rats' skeletal muscle(soleus m) and blood insulin level after 12 hr fasting condition and one hour treadmill running. Total 19 rats(Sprague-Dawley) who were 7week Did were used for experimental subjects and raised for 1week in the room controled the air temperature and relative humudity(22℃ and 50%). They were divided three groups ; 12hr fasting group(F group, n=5), fasting+exercise group(FE, n= 7) and fasting+caffeine+exercise group(FCE group, n=7). FG and FCE group performed treadmill running for one hour and the treadmill speed was 18m/min that was supposed to be moderate exercise to rats. Each Dr rats in FCE group was forced to he given the caffeine solution(5mg/kg, Sigma Chemical co.) through stainless steel tube directly to their stomachs one hour before treadmill exercise. Immediately after treadmill running, we anesthetized them with the mixed solution(Ketamin 80g/kg and Rompun 5ml/kg) to draw 3ml blood from heart four insulin analysis and then obtained the rats' soleus muscle for GLUT-4 expression. We found that FCE group showed significantly higher GLUT - expression then the other groups and FE group showed the lowest GLUT-4 expression. This rusults suggest that the endurance type of exercise in fasting condition inhibit the GLUT-4 expression in working muscle and the caffeine helped to facilitate the GLUT-4 expression during endurance type of exercise. The future studies needed to confirm the action of caffeine to increase the GLUT- 4 and the mechanism.

      • SCIESCOPUSKCI등재
      • Maize Variety Adapted to Late Planting in June for the Double Cropping of Forage Maize-Barley

        Jong-Ho Seo,Jae-Eun Lee,Gun-Ho Jung,Young-Up Kwon,Chun-Ki Lee,Beom-Young Son,Sung-Beom Baek,Wook-Han Kim 한국작물학회 2010 한국작물학회 학술발표대회 논문집 Vol.2010 No.04

        Maize is expected to be planted in June after harvest of winter barley for the double cropping of forage maize-barley. But maize yield tends to be reduced rapidly with late planting after mid-May, so the pre-requisite of maize variety for the double cropping of maize-barley is less reduction of growth and yield at the condition of late planting in June. In order to select domestic forage maize variety adapted to late planting in June after barley harvest, Kwangpyeong-ok, Gangda-ok and Jangda-ok in 2007 and Kwangpyeong-ok, Gangda-ok and Cheongan-ok in 2008 were planted on June 13 and June 21, and plant growths and yields were compared with early planting on April 24 and May 31, respectively. In 2007, Ear number per plant was as high as 0.98 at Kwangpyeong-ok compared to 0.89 and 0.56 of Gangda-ok and Jangda-ok, respectively, at late planting on June 13. TDN and grain yield of Kwangpyeong-ok were the highest among three variety as 1,037 and 710 kg/10a, and yield reduction of Kwangpyeong-ok compared to early planting were 24% and 28 %, which were 7% and 8% lower than Gangda-ok and 22% and 50% lower than Jangda-ok, respectively. In 2008, TDN and grain yield at late planting on June 21 of Kwangpyeong-ok were also the highest among three varieties as 1,157 and 854 kg/10a at late planting on June 24, and yield reduction of Kwangpyeong-ok by late planting were 21% and 19%, which were 10% and 11% lower than Gangda-ok and 22% and 50% lower than Jangda-ok, respectively. It was concluded that proper maize variety adapted to late planting for the double cropping of forage maize-barley was Kwangpyeong-ok because of its higher ear bearing, less reduction of TDN and grain yields at the condition of late planting.

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