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      • Slide Session : OS-IFD-07 ; Infectious Disease : In Vitro Antiviral Activity of Ribavirin Against Severe Fever with Thrombocytopenia Syndrome Virus

        ( Myung Jin Lee ),( Kye Hyung Kim ),( Jong Youn Yi ),( Su Jin Choi ),( Chung Jong Kim ),( Nak Hyun Kim ),( Kyoung Ho Song ),( Pyoeng Gyun Choi ),( Ji Hwan Bang ),( Wan Beom Park ),( Eu Suk Kim ),( San 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        In Vitro Antiviral Activity of Ribavirin Against Severe Fever with Thrombocytopenia Syndrome Virus Myung Jin LEE1, Kye-Hyung KIM1, Jongyoun YI2, SuJin CHOI1, Chung-Jong KIM1, Nak- Hyun KIM1, Kyoung-Ho SONG1, Pyoeng Gyun CHOI1, Ji-Hwan BANG1, Wan Beom PARK1, Eu Suk KIM1, Sang-Won PARK1, Hong Bin KIM1, Nam Joong KIM1, Myoung- Don OH1 Seoul National University College of Medicine, Korea1, Pusan National University School of Medicine, Korea2 Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by a novel Bunyavirus, severe fever with thrombocytopenia syndrome virus (SFTSV). No effective antiviral therapy is proven yet, but clinical use of ribavirin (RBV) has been tried. We investigated the antiviral effect of RBV against SFTSV in vitro. Methods: To test for cytotoxicity of RBV, Vero cells were treated with different concentrations of RBV (3.90 to 500 μg/mL, two-fold dilution) and analyzed by cell viability MTS assay 48h post-infection. To determine antiviral activity of RBV against SFTSV, Vero cells were infected with SFTSV strain Gangwon/Korea/2012 at 100 TCID50 (50% tissue culture infective dose) per well in a 96-well plate, and RBV was added at the concentrations showing no or minimal cytotoxicity. Viral RNAs were extracted from the culture supernatants and quantifi ed using one-step real-time reverse transcription- PCR to amplify the partial large segment of SFTSV. Statistical analysis was done by one-way ANOVA with Tukey`s post hoc test. Results: Cytotoxicity due to RBV was not observed at RBV concentration =31.3 μg/ mL. Viral RNAs at 24h post-RBV treatment were reduced with increasing RBV concentrations (1-32 μg/mL), compared with those of mock-treated cells (P <0.01, Figure). Half maximal inhibitory concentration (IC50) of RBV was 3.69 μg/mL at 24h post-RBV treatment. Conclusions: Our study shows that RBV has antiviral effect against SFTSV in a dose-dependent manner. Further studies are required to evaluate the effi cacy of RBV in SFTS.

      • KCI등재

        한국 사회복지정책의 정치·경제적 요인에 관한 연구 : 제 4공화국에서 국민의 정부까지 From four the republic of korea to mass government

        박범종 釜山大學校 韓國民族文化硏究所 2005 한국민족문화 Vol.25 No.-

        Korea's social welfare policy has improved for 20 years. However, korea's welfare level is very lower than other advanced countries. There are many reason about falling behind the social welfare level. So, I have douts its situation and what kind of factors have effect on the social welfare policy's decision making? This these aim is to evaluate the relative importance of political and economic factors as the determinants of social welfare policy and what kind of factor is very important of policy making? This research try to find the determinants of social welfare decision from 4 republic to mass government. And then, we will have known the reason of the falling of the social welfare policy. This research has analysis with co-relation. This research use dependent variable as like social welfare expenditures of korea central government and welfare expenditure per a man and use independent variables as GNI, unemployment, the industrial ratio, the seat ratio of ruling party, defense expenditure and existence or not of election. Finally, we gain the this result from this research. While it is 4, 5, 6 republic, economics factor has important effect on the social welfare policy and political factor is not effect on it because labor power is not organized and is not connected with the political power. However, this labor power is constructed after 6 republic. When it is civil-government and mass government period, labor power is connected with political power as like democratic labor party at this period. Finally, political factor turn up the important factor in the social welfare policy. This research's important meaning is used measuring analysis to find out the important factor of social welfare policy and this study will be contribute to improve social welfare policy and level in korea.

      • 지문인식의 특이점 추출 알고리즘 구현

        박종민,조범준 조선대학교 전자정보통신연구소 2003 電子情報通信硏究所論文誌 Vol.6 No.1

        본 논문에서는 특이점 추출에서의 과다한 추출 단계로 인하여 발생되는 문제점들을 줄이기 위하여 기존의 6단계인 특이점 추출 과정을 개선하여 3단계로 줄이면서도 정확성을 높이는 특이점 추출 알고리즘을 설계/구현하고자 한다.

      • 장기요양보험제도의 사회적 가치에 관한 연구 : 부산을 비롯한 광역시를 중심으로

        박범종 신라대학교 부산학연구센터 2010 부산연구 Vol.8 No.1

        본 연구는 장기요양보험제도가 시행된 지 2년이 되는 시점에서 장기요양보혐의 필요성을 살펴보고, 부산을 비롯한 대구, 인천, 광주, 대전, 울산광역시를 중심으로 장기요양보험의 시설 및 재가의 실태 현황을 비교분석한다. 이러한 논의를 바탕으로 장기요양보험제도가 가져온 사회적 가치와 기대효과에 대해 연구하였다. 그 결과 부산, 대구 그리고 인청 지역이 다른 지역에 비해 고령화 속도가 빠르며, 의료급여수급자(기초생활 수급자)비율에 있어서도 부산이 타 광역시보다 훨씬 높은 비율을 보였다. 따라서 이러한 결과를 바탕으로 볼 때 부산은 비교적 요양시설과 재가시설의 확충노력이 더 필요함을 알 수 있다. 장기요양보험이 가져온 사회적 가치와 기대효과를 살펴보면, 크게 세 가지로 요약된다. 첫째, 장기요양보험 제도 운영에 있어 요양시설 및 재가시설등의 인프라 확충으로 노인성 질환을 앓고 있으면서 서비스 혜택을 받지 못하는 노년층의 삶의 질을 높이고 있다. 둘째, 장기요양서비스를 받는 당사자 및 가족의 삶의 향상되고 가정의 부양부담이 경감되었다. 이러한 여러가지 사회적 가치를 고려할 때 장기요양보험제도의 성공적인 발전과 확충이 필요하다.

      • 제6회 전국동시지방선거에서 부산시민의 선택과 미래 : 부산광역시장 선거를 중심으로

        박범종 신라대학교 부산학연구센터 2014 부산연구 Vol.12 No.-

        본 연구의 목적은 제6회 전국동시지방선거에서 부산시민이 선택한 서병수 부산시장 당선인의 정책공약을 토대로 부산의 미래가 어떠할지에 대해 점검해보는데 있다. 정치에서 미래는 유권자의 몫이다. 왜냐하면 유권자의 선택에 따라 그 지역의 미래가 달라지기때문이다. 6.4 지방선거 결과 부산시민은 서병수 후보를 선택했고, 강하고 포용력있는 리더십을 요구하고 있다. 또한 부산의 미래는 서병수 부산시장이 내세운 핵심공약 5개의 실천여부에 달려있다. 따라서 부산시장 서병수 당선인이 제시한 12대 분야, 60개 세부공약 중에서 핵심공약으로 내세운 5개 공약 ① 임기 중 안정적 일자리 20만개 창출 ② 안전도시 부산: 선진국 수준의 안전도시 구축 ③ 신공항 가덕도 유치 ④ 도시재생을 통한 부산 재창조 ⑤ 사상스마트 시티 조성에 대한 한국매니페스토실천본부의 평가를 중심으로 부산의 미래를 점검 및 분석하였다.

      • KCI등재

        재외선거 현황 분석과 투표율 제고방안 : OECD국가의 재외선거제도 비교와 미국, 중국, 일본의 설문조사를 중심으로

        박범종 부산대학교 한국민족문화연구소 2012 한국민족문화 Vol.44 No.-

        This study examines how to improve turnout of voters through a comparative study of OECD country’s overseas voting institute and survey of American, China and Japan. We have to explain the processing on overseas voting in 19th Assembly election. particularly the evaluation of koreans compare to OECD country’s overseas voting institutes and analysis on the survey about issues of qualified as a voter, object elections, a overseas voter registration and voting and a way of election campaign on overseas country. According to this result, we suggest a improvement plans of a turnout of voters First, we don’t have to permit of double nationality about overseas voting. however, it is a rational to permit of only double nationality over 65 year old. Second, we have to admit on the presidential election and Proportional Representative National Assembly elections. Third, we have to use an variety methods as like personal visit at diplomatic missions, postal, internet for overseas voter registration. Fourth, we must be expanding plan of personal voting at diplomatic mission and postal voting, e-voting. fifth, we must admit of overseas election campaigning just like broadcasting and internet without additional conditional. 본 연구는 재외선거의 공정성과 투명성의 문제를 넘어서 실제 투표율을 어떻게 하면 높일 수 있는가에 초점을 맞추고 있다. 그래서 우리나라의 현재외선거제도와 OECD국가의 재외선거제도 비교 및 미국, 중국, 일본에서 실시한 설문조사 결과를 바탕으로 선거권자, 대상선거, 선거등록 방법 및 투표방법 그리고 국외선거운동방법으로 구분해서 우리나라 재외선거의 투표율을 높이기 위한 방안을 제안한다. 첫째, 선거권자에 있어 시민권자가 아닌 모든 재외국민들에게 선거권을 부여해야 하며, 복수국적을 완전히 허용하는 것은 아직 시기상조라고 생각된다. 둘째, 대상선거에 있어 재외국민들이 참여할 수 있는 선거를 대통령제와 비례대표제에만 한정하는 것이 더 효율적이라고 생각한다. 셋째, 선거등록 방법에 있어서는 신청주의와 영구명부제로의 전환이 필요하다. 또한 신청방안에 있어 현재 인정하고 있는 재외공관등록 외에 인터넷과 우편등록을 허용해야 한다. 넷째, 투표방법에 있어서는 재외공관 투표 외에 우편투표 및 인터넷투표를 점차적으로 허용하는 방안을 모색해야 할 것이다. 그리고 우리나라는 2012년 국회의원 선거에서 OECD국가에서 시도하지 않은 재외공관에서 투표용지를 프린터로 발급해 기표식으로 투표하는 방식은 비용절감효과 측면에서 매우 긍정적으로 평가한다. 다섯째, 국외선거운동에 있어서는 국내위성방송과 정보통신망을 통한 선거운동이 활발하게 허용해야 한다. 또한 한인단체와 한인언론, 그리고 여론주도층을 대상으로 재외선거에 대한 인식과 설명회를 통한 홍보를 활용한 적극적 홍보도 필요하다.

      • 벼 乾畓直播栽培에서 Propyl Dihydro Jasmonate 種子處理에 따른 出芽 및 生育促進效果

        박종현,이철원,송범헌,손석용 忠北大學校 農業科學硏究所 2003 農業科學硏究 Vol.20 No.-

        This study was conducted to examine the effects of Propyl Dihydro Jasmonate on the growth responses, chilling tolerance and yields on the direct seeding on dry paddy at seedling stage in two rice cultivars The emergence rate of two rice cultivars (Seoan byeo and Dasanbyeo) were increased more by the treatment of 0.05μM PDJ than those of others. Higher concentration of PDJ was found to be inhibitory for germination. Number of emergence of cultivar Seoanbyeo was higher in 0.05μM PDJ treatment for 24hour as compared to 12hour, whereas, no significant difference was observed in case of cultivar Dasanbyeo Plant height and number of tillers of two rice cultivars were increased by the treatment of 0.05μM PDJ for 24 hour Rice yield of the tested cultivars were increased high in the PDJ treatment plot due to increment of the panicle number in the dry seesed paddy field.

      • PFA / Silica 유-무기 복합체의 제조 및 표면특성

        범정철,하종욱,박인준,이수복 한국공업화학회 2003 응용화학 Vol.7 No.1

        Poly(perfluoroalkyl acrylate)(PFA) / silica composites having different silica size were prepared by surface polymerization. In this study, surface characterizations of PFA/silica composites were done by HR-TEM(High Resolution Transmission Microscopy), contact angle measurement, sliding angle measurement, surface roughness measurement, and the relationships between the sliding angle and the contact angle were investigated. In the highly hydrophobic region, the sliding angles of water droplets decreased with increasing contact angle. Their surface free energies were calculated with contact angle data by geometric mean approximation. The composites with super water repellent and sliding could be obtained with contact angle of above 150。and sliding angle of below 10。to water droplets. The ultimate value of surface free energies of the composites reached below ca. ldyn/cm.

      • 農家副業으로서의 畜産現況과 그 改善方案에 關한 硏究

        洪鐘旭,李熙碩,朴恒均,崔源弼,李鉉凡,金祥基 慶北大學校 1978 論文集 Vol.25-26 No.-

        Recently, there have been much corncerns about the strategies which can reasonably increase farm income at the average farm level. In other words, as a result of third-term Five Year Economic Development Plan there was a remarkable gap between farm household and non-farm household incomes. Therefore, various policy tasks to eliminate this unbalanced income growth are currently being implemented. This study was carried out to identify the situation of livestock farming at general farm level, regarded as one of income generation strategies for the farm sector. Some results of the study can be summarized as follows: First of all, it was found that a group of farms which raise a small size of animals like Korean cattle, hog, and various poultry gave higher resource bases as compared with that of non-livestock farms. Secondly, it was also recognized that both farm and farm household income levels of small-scale livestock farms were higher than those of non-livestock farm group within the same region, specifically as much as approximately ₩200,000. Thirdly, it was known that the average size of animal raising per household in 0.9 head of cattle, 0.8 head of hog, and 34 lyers of poultry, respectively. To the end, according to the farm disposal practices of major by-products, only about 18 percent of total rice straws produced at individual farms was utilized for the animal raising, and about 45 percent of all the brans available at farms for the livestock enterprise. The rest of straw and brans in regarded as selling at farm level. In this respect, it may be recommended either to increase current size of animals or to expand number of livestock farms.

      • 오염된 연약지반의 변위량 분포에 관한 연구

        안종필,박상범 朝鮮大學校 建設技術硏究所 1998 建設技術硏究 Vol.18 No.2

        This study investigates the existing theoretical backgrounds in order to examine the behavior of lateral flow according to the plasticity of soils when unsymmetrical surcharge is worked on polluted soils by the increase of water content and compares and analyzes the results measured through model tests. Model tests are carried out by these : soil tank, bearing frame and bearing plate are made, the water content is soil tank was gradually by increasing ground soils in natural ground of soils and polluted material, unsymmetrical surcharge is increased at regular intervals and then the amounts of settlement, lateral displacement and upheaval are abserved. As the result of model tests, the amount of settlement had a tendency to occur transferring from the left boundary line to the free end of bearing plate, the amount of lateral displacement is occurred concentratively in the range of (0~2/3)H of the thickness of soil layer and that of upheaval soil tank a tendency to transfer from the right boundary line to the ground surface of the free layer of bearing plate.

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