Paraquat 중독환자의 초기검사로서 sodium dithionite를 이용한 소변내 paraquat검출의 임상적 의의

윤갑준,임경수,이진웅,김영식,이부수,박덕우,김선만,이강현,황성오,안무업 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

Background : Mortality from paraquat intoxication depends upon plasma paraquat concentration. To know the severity of paraquat intoxication is important for directing therapeutic modality and predicting prognosis. Sodium dithionite test for urinary paraquat provides an easy and simple method to determine the severity of paraquat intoxication in emergency department. purpose : To determine whether the result urinary paraquat test by sodium dithionite can predict outcome in patients with paraquat intoxication in emergency department. Subjects : 48 patients(male 31, female 17, mean age 37 years) who had exposure to paraquat and presented within 24 hours after exposure. Result : Thirty five patients were positive in paraquat urine test and thirteen patients were negative. Clinical manifestations were more severe in positive patients than in negatives. Complication was much more in positives than in negatives. 28 of 35 patients(80%) in positives and 2 of 13 patients(15%) in negatives died. Conclusion : Positive test for urinary paraquat is associated with high mortality and morbidity from paraquat intoxication, and qualitative test for urinary paraquat by sodium dithionite is an useful method to determine the severity of paraquat intoxication in emergency department.

아침형과 저녁형 사람에서 야간의 졸리움, 수행 및 체온의 비교

윤진상,국승희,신일선,신만식,최영,이무석,이형영 大韓睡眠-精神生理學會 1994 수면·정신생리 Vol.1 No.1

진행된 HIV 감염 환자에서 십이지장의 미란성 병변으로 발현한 Mycobacterium genavense 감염 1예

진상만,박종선,김홍빈,오명돈,최강원,김희연,국윤호,김남중 대한감염학회 2007 감염과 화학요법 Vol.39 No.4

Mycobacterium genauense는 최근에 알려진 미코박테륨으로서, 식욕 부진, 체중 감소, 설사, 림프절 병증 등 파종성 Myocobacterium avium-intracellulare complex 감염과 유사한 임상상을 보이며, 위장관 침범을 잘 하는 것으로 알려져 있으나 아직 국내에서 증례는 보고된 바가 없다. 저자들은 진행된 HIV 감염 환자에서 십이지장의 미란성 병변으로 발현한 Mycobacterium genavense 감염 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. 환자는 상복부 동통과 발열, 설사로 내원하였다. 십이지장의 미란성 병변에서 시행한 조직검사에서 항산균이 가득 차있는 거품세포가 관찰되었으며, 이 검체에서 16S rRNA 유전자의 중합연쇄반응 검사를 시행하여 Mycobacterium genavense를 확인하였다. Mycobacterium genavense, first identified in 1990, is known as a pathogen that mimics disseminated Myocobacterium avium-intracellulare complex (MAC) infection with particular propensity for the gastrointestinal tract. In Korea, no case with the organism has been reported. Herein we report a case of Mycobacterium genavense infection that manifested with erosive lesion of duodenum in a patient with acquired immune deficiency syndrome. The patient presented with epigastric pain and fever, diarrhea. Duodenal biopsy showed histiocytic infiltration with numerous acid-fast bacilli. Identification of the mycobacterial isolate by the polymerase chain reaction restriction analysis of 16S rRNA gene revealed Mycobacterium genavense.

육상경기 선수들의 체격과 운동능력 특성 분석

김만호,윤양진 釜山大學校 附設 體育科學硏究所 1997 體育科學硏究所 論文集 Vol.13 No.-

The purpose of this study was to analyse the characteristics of physique and physical fitness and to investigate the effects of athlete's body conposition and physical fitness to athletic performance of sprinters, middle and long distance runners, jumpers and throwers group with 160 track and field athletes of Boy's and Girl's middle and high school in Pusan metropolitan city. In this study 7 factors in body conposition, 9 factors in physical fitness and 16 factors in were measured and analyzed. The results of the study were as follows; 1. The characteristics of the body conposition factors 1) In Boy's middle school throwers group was the biggest and middle and long distance runners group was the smallest in each factors. Throwers group was the biggest in girth bulk among all groups and smaller than jumpers group in standing height in Girl's middle school. 2) In Boy's hight school jumpers grour in length factors and throwers group was bigger in girth and bulk than other groups. Throwers group was the biggest and middle and long distance runners group was the smallest in each factors in Girl's high school. 2. The characteristics of the physical factors 1) In Boy's middle school throwers group was higher in muscular strength agility and flexibility, sprinters group in muscular strength and power, and middle and long distance runners group in balance than other groups. Throwers group was higher in muscular strength and balance, and middle and long distance runners group was the lowest in muscular strength and power than other groups in Girl's middle school. 2) In Boy's high school throwers group was higher in muscular strength, sprinters group in power, flexibility and balance, and middle and long distance runners group in balance, but they were the lowest in other factors. Throwers group was higher in muscular strength, jumpers group in power and balance than other group's in Girl's high school.

토양 미생물인 Streptomyces tubercidicus에서 분리한 GTPcyclohydrolase Ⅰ 저해제

한지만,김시욱,이인화,박열,정혜광,윤성명,유진철 조선대학교 약학연구소 1998 藥學硏究誌 Vol.19 No.1

GTP cyclohydrolase I (EC 3.5.4.16) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphates and formic acid. and thus performs the first committing step in the biosynthesis of the pteridine moiety of folk acid in microorganisms and of tetrahydrobiopterin in higher animals. GTP cyclohydrolase I isolated from Streptomyces tubercidicus was inhibited by DL-6-methyl-5,6,7,8-tetrahydropterin and xanthopterin, and was not inhibited by tetrahydrofolic acid, pterin, pterin-6-carboxylic acid, biopterin, neopterin, ribofravin. These results suggest that bacterial GTP cyclohydrolase I may be regulated by its metaboilic end product.

초등학교 운동선수들의 체격, 신체 구성 및 체력의 특성 분석

김만호,윤양진,최민동 釜山大學校 附設 體育科學硏究所 1998 體育科學硏究所 論文集 Vol.14 No.-

The purpose of this study was to look into the factors influencing ability of the game and to give information on selecting the superior player. In elementary school, twenty body of sixth grade were selected as subject for swimmer, football player and, athletes. It measured and compared eight items of physique, four items of body composition and six items of physical fitness as test items The correlation was analyzed to find out the relationship of physique to body composition, physical fitness to body composition, and physique to physical fitness in each sports. 1. The correlation analysis of physique, body composition and physique fitness. 1) The football play was superior to swimmer and athletes only in the thing girths. 2) Standing height, sitting height, up lime length, lower limb length, lower limb length, upper arm girth, chest girth, and body weight all had litter significance. 2. Body composytion comparison 1) Swimmer was better than football player and athletes in percentage of body fat(%fat) and total body fat(%TBF). 2) Football players and athleres were superior to swimmer when comparing body density. 3) there were no significant differences in lean body mass. 3. Comparison of physical fitness 1) Athletes was superior to swimmer and football player in muscular endurance, power, flexibility and agility. 2) There weren't any significant differences in muscle strength and balance. 4. The canonical correlation analysis of physique, body composition and physical fitness 1) Swimmer, football player, athletes all had high interrelationships between physique and body composition(.987), body composition and physical fitness(.973), physique and physical fitness(.967).

우수 사과酒酵母의 分離와 利用에 關한 硏究

朴允仲,金燦祚,李錫健,吳萬鎭,孫天培 충남대학교 농업과학연구소 1978 農業技術硏究報告 Vol.5 No.1

Extensive selection works on wild yeasts of fruits were carried cut to obtain strains which are applicable to apple wine making. Among the total number of 1,358 yeast strains which were isolated from various fruit samples collected from the vicinity of Daejeon and other regions of Korea, the strains SH-49, SH-129 and SH-338 were found to be useful. Then experiments on their morphological and physiological characteristics, and on the aspects of practical use in apple wine making were proceeded. The results obtained were as follows: 1. The strains SH-49 and SH-129, particularly SH-49, were appeared to have good fermentation ability, tolerance to sulfur dioxide and to produce fine quality of apple wine. 2. Apple wines made by using the strain, SH-49 and SH-129 contained less amount of total acids than those by other strains. 3. Apple wines of SH-49 and SH-129 were clarified rapidly during the primary fermentation period, and their absorbancy at 430 nm after 45 days of storage were approximately half of others. 4. Apple wine of SH-338 contained higher amount of residual sugar and its quality was superior to others. It is considered that this strain could be used in the production of apple wine of a characteristic quality. 5. The strains SH-49 and SH-338 were identified as a Saccharomyces cerevisiae according to Taxanomic Study of Yeasts by Lodder, however, classification of SH-129 was suspended for further study.

大邱地域 中小企業의 效率的인 技術開發 方案에 관한 硏究

全瑨文,張晩植,尹在坤,金圭昌,李栽燁,朴筍植,黃建夏 효성여자대학교 산업경영연구소 1988 경영경제 Vol.5 No.-

For modern business firms, the most important factor in determining comprtitiveness of a firm is technology, rather than capital. Technogical innovation is a driving force to develop an economy and is essential in growth and/or survival of a business firm. Following studies concerned with this subject, small business firms seem to be more efficient in technological innovation and developing new technology in several respects. Espercially in the new technology based industries, the small business firms have several advantages in technological innovation. In this study, we tried to show how to plan a technology development strategy in relation to management strategy when small business of theoretical and empirical study, we aimed to show the way to efficient management and procedure of technological innovation. For the research methodology, we firstly reviewed and analyzed current and previous studies about technological innovation strategy, efficient management, and selection of R&D projects. Secondly, the results of this theoretical study was examined empirically. The empirical study contains 153 questionaires and 30 interviews for business firms of this area. In addition, for the evaluation criteria for the selection of R&D projects, we sent questionaires to 60 professors who teaches R&D OR in university or college level. The result of these questionaires was analyzed and compared with that of the business firms of this area. The result of this empirical study shows that top management of small business firms should notice the importance of technological innovation and try to stimulate R&D activity. For the evaluation criteria for R&D projection, the criteria which could reduce the possibility of future uncertainty, maximize profit, and he suited for the situation of the business firm, should be established.

대구 및 인근지역의 도로먼지에 함유된 미량원소성분의 함량분포

황윤정,황승만,최진수,김무식,백성옥 嶺南大學校 環境問題硏究所 1998 環境硏究 Vol.17 No.2

요약문 본 연구는 각종 먼지 가운데서도 독성이 가장 큰 것으로 알려진 도로먼지에 함유된 미량원소 성분이 조성 및 특성을 파악하기 위해 1992년 1월에서 10월가지 주거지역, 상업지역, 공업지역, 교외지역, 전원지역 등에 위치한 도로에서 시료를 채취하였으며 채취된 시료는 산으로 추출한후 ICP로 분석하였다 . 그 결과 토사 및 황사현상과 같은 자연발생원과 연관지을 수 있는 Al, Ca, Mg, Ti, Si, Na, K의 농도가 지역에 따라서는 전원지역과 교외지역에서, 그리고 도로포장 형태에 따라서는 비포장 도로에서 높게 나타난 반면에, 각종 연소 및 차량과 같은 인위적인 발생원과 관련이 있는 As, Cr, Mn, Zn, Pb, Cu, Ni는 공업지역 및 상업지역, 그리고 아스팔트에서 비교적 높게 검출되어 이러한 미량원소성문들의 농도분포는 지역에 따라, 그리고 도로포장 형태에 따라 특징적인 양상을 나타내는 것으로 조사되었다. 또한 As, Pb, Al 등의 일부 미량원소성분들의 농도는 계절에 따른 차이를 나타내었으며, 농축계수에 의한 평가결과 농축계수가 낮게 나타난 Na, Si, Ti, K, Al 등은 자연발생원에 의해 상당한 영향을 받는 반면에 As, Pb, Zn 등은 농축계수가 매우 높게 나타나 이들 성분의 경우에는 인위적인 발생원에 의한 기여도가 큰 것으로 평가되었다. Abstract This study was carried out to characterize the trace elements in street dust known to contain several toxic elements. Street dust was collected in residential, commercial, industrial, suburban and rural area of Taegu and on the vicinity of Taegu from January to October, 1992. Total amount of 16 trace elements in street dust were analyzed by ICP spectrophotometer. While the levels of As, Cr, Mn, Zn, Pb, Cu and Ni were higher in industral and commercial area than any other area by sites and the highest levels appeared on asphalt and cement street by street conditions. Also the concentrations of some trace elements originated mainly from soil (e.g. Al, Ca, Mg, Si, Na) were higher in rural and suburban area by sites and the highest levels appeared in unpaved street by street conditions. The concentrations of several trace elements such as Aa, Pb, Al appeared seasonal differences. The estimated enrichment factors (EF) for Na, Si, Ti, K and Al components showed with soil compositions appeared to have low values, while As, Pb and Zn components showed relatively higher values. These results imply that the latter constituents were likely to be affected by dry and wet depositions of atmospheric particles orginated from anthropogenic sources such as fuel combustion and refuge burning.

음향방출과 미세역학적시험법을 이용한 단일섬유강화 에폭시 복합재료의 비파괴적 섬유파단 위치표정 및 계면물성 평가

박종민,공진우,김대식,윤동진 한국비파괴검사학회 2003 한국비파괴검사학회지 Vol.23 No.5

섬유파단은 복합재료의 기계적물성을 규명하는 가장 중요한 현상 중 하나이며, 섬유파단 위치는 기지재료의 물성과 섬유표면 처리에 따라 광학현미경에 의한 방법 뿐만 아니라 음향방출법을 이용하여 확인 및 상호비교 할 수 있다. 두 개의 음향방출 센서를 단일섬유강학 에폭시 복합재료 시편 표면에 부착 시켜 연속적인 섬유파단 신호를 변형률과 측정 시간에 따라 감지하였으며, 계면전단강도는 단일섬유강화 복합재료 시험에서 광학적 방법과 음향방출법을 이용하여 측정하였다. 탄소섬유의 파단 수는 섬유표면을 전기증착으로 처리한 경우가 많았으며, 광학적인 관찰 시에 좀 더 많게 나타났다. 하지만 음향방출법과 광학적 방법에 의한 섬유파단의 위치는 작은 오차범위 내에서 상호 잘 일치하는 결과를 얻을 수 있었다. 음향방출법에 의한 섬유파단 위치표정과 파형분석은 투명, 반투명 및 불투명한 복합재료의 계면물성을 비파괴적으로 측정하기 위한 유용한 방법으로 사료된다. Fiber fracture is one of the dominant failure phenomena affecting the total mechanical performance of the composites. fiber fracture locations were measured through the conventional optical microscope and the nondestructive acoustic emission (AE) technique and then were compared together as a function of the epoxy matrix modulus and the fiber surface treatment by the electrodeposition method (ED). Interfacial shear strength (IFSS) was measured using tensile fragmentation test in combination of AE method. ED treatment of the fiber surface enlarged the number of fiber fracture locations in comparison to the untreated case. The number of fiber fracture events measured by the AE method was less than optically obtained one. However, fiber fracture locations determined by AE detection corresponded with those by optical observation with small errors. The source location of fiber breaks by AE analysis could be a nondestructive, valuable method to measure interfacial shear strength (IFSS) of matrix in non-, semi- and/or transparent polymer composites