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창면 불쾌글레어 평가실험의 조건설정 및 타당성 검토를 위한 기초실험
김선화,김병수,이진숙 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1
The purpose of the study is to found the base experimental data by testing the adaptable time of eyes with administrating experimental conditions including source luminance, background illuminance and the position of subjects, by examining the appropriation of evaluating discomfort glare caused by actual window and simulated window. The process of the study is as follows: 1) In terms of the previous experiment, the large of Mock-up, evaluation values and subjective positions were administrated. 2) The experiment on the adaptable time of eyes is conducted with source luminance, background illuminance and the subjective position. 3) At the same Mock-up condition, the experiments for evaluating discomfort glare caused by actual window and by simulated window were conducted and contrasted. The adaptable time of eyes is rationally tested as 120 seconds with source luminance, background illuminance and the subjective position. And the difference on the boundary of evaluating values caused by actual window and simulated window ranges from 13% to 5%. On the basis of the result, the applicability of evaluating discomfort glare caused by simulated window is presented
창면불쾌글레어 평가를 위한 인공창 실험의 타당성 검토 연구
이진숙,김병수,김선화 대한건축학회 2003 대한건축학회논문집 Vol.19 No.12
The purpose of this study is to find the base experimental data by testing the recovery time of human eye with administrating experimental conditions, source luminance, background illuminance and the position of subjects, by examining the appropriateness of evaluating discomfort glare caused by actual window and by simulated window. The process of this study is as follows: 1) In terms of the previous experiment, the large of Mock-up, evaluation values and subjective positions were administrated. 2) The experiment on the recovery time of human eye is conducted by source luminance, background illuminance and the subjective position. 3) At the same Mock-up condition, the experiments for evaluating discomfort glare caused by actual window and by simulated window were conducted and contrasted. Rationally tested recovery time of human eye is 120 seconds with source luminance, background illuminance and the subjective position. And the difference on the boundary of evaluating values caused by actual window and by simulated window ranges from 13% to 5%. On the basis of the result, the validity of discomfort glare evaluation caused by simulated window is presented.
Synergistic Effects of Leflunomide and Benazepril in Streptozotocin-Induced Diabetic Nephropathy
Jin, Hua,Piao, Shang Guo,Jin, Ji Zhe,Jin, Ying Shun,Cui, Zhen Hua,Jin, Hai Feng,Zheng, Hai Lan,Li, Jin Ji,Jiang, Yu Ji,Yang, Chul Woo,Li, Can S.Karger 2014 The Nephron Journals Vol.126 No.3
<P>Abstract</P><P><B><I>Background:</I></B> Leflunomide (LEF) and benazepril have renoprotective effects on diabetic nephropathy (DN) through their anti-inflammatory and anti-fibrotic activities. This study investigated whether combined treatment using LEF and benazepril affords superior protection compared with the respective monotherapies. <B><I>Methods:</I></B> Diabetes was induced with streptozotocin (STZ, 65 mg/kg) by intraperitoneal injection in male Wistar rats. Two weeks after STZ injection, diabetic rats were treated daily for 12 weeks with LEF (10 mg/kg), benazepril (10 mg/kg), or a combination of both. Basic parameters (body weight, fasting blood glucose level, and 24 h urinary protein excretion), histopathology, inflammatory [inflammatory cell infiltration (ED-1), monocyte chemoattractant protein-1 (MCP-1), and Toll-like receptor-2 (TLR-2)] and glomerulosclerotic factors [transforming growth factor-β<SUB>1</SUB> (TGF-β<SUB>1</SUB>) and connective tissue growth factor (CTGF)], and oxidative stress (8-hydroxy-2'-deoxyguanosine, 8-OHdG) were studied. <B><I>Results:</I></B> Benazepril or LEF treatment significantly prevented body weight loss and 24 h urinary protein excretion induced by diabetes; combined treatment with LEF and benazepril further improved these parameters compared with giving each drug alone (all p < 0.01). Increased expression of inflammatory (MCP-1 and TLR-2) and glomerulosclerotic (TGF-β<SUB>1</SUB> and CTGF) factors in diabetic rat kidney was reduced by treatment with either LEF or benazepril and was further reduced by the combined administration of the two drugs (p < 0.01). These effects were accompanied by suppression of urinary 8-OHdG excretion. There was no significant between-group difference in blood glucose level. <B><I>Conclusions:</I></B> LEF treatment lessens DN, and combined treatment with LEF and benazepril provides synergistic effects in preventing DN.</P><P>© 2014 S. Karger AG, Basel</P>
(2019년 국제학술대회)桂林三戏”戏曲品牌文化旅游开发路径研究
Jin-hua Jiang(蒋,金桦,),Xiu-bai Li(李秀白) 융합관광콘텐츠학회 2019 융합관광콘텐츠학회 학술대회 발표집 Vol.2019 No.-
The purpose of the study to analyzes the problems existing in the development of opera cultural tourism resources on Three Operas in Guilin . First of all, the development model of opera culture resources is relatively simple and lacks brand image. Secondly, the interaction between the opera performance and the tourists is low, the performers rarely communicate with the tourists, the tourists have a weak understanding of the three local operas.Thirdly, the theater company has difficulties in operating and lacks professional drama talents. In addition, the older generation of artists is aging, which leads to the serious loss of traditional plays and weakens the attraction of local opera tourism development. Finally, the lack of propaganda and the lack of channels for the promotion of opera culture. Based on the above problems, this study explores the development path of the brand culture tourism of Three operas in Guilin . First, integrating opera cultural resources and regional tourism resources. Second, innovating drama culture tourism development model, using the art museum, theme park, opera experience hall and festival activities to create a Three operas in Guilin opera brand cultural tourism, enriching the Guilin local opera culture tourism model structure. Third, shaping the brand image of “Three operas in Guilin” and forming a cultural tourism project with Guilin characteristics. Fourth, improving the inheritance of the Three operas in Guilin and the system of training talents for opera, strengthening the interaction between opera performers and tourists, and increasing the attractiveness of tourists. Finally, broadening the publicity channels of traditional Chinese opera culture, strengthening the publicity, and improving tourists perception of traditional Chinese opera.
Jin, Hua,Kim, Hyun-Woo,Xu, Cheng-Xiong,Kwon, Jung-Taek,Hwang, Soon-Kyung,Lee, Eun-Sun,Chang, Seung-Hee,Park, Sung-Jin,Noh, Mi-Suk,Woo, Min-Ah,Yu, Kyeong-Nam,Lee, Hu-Jang,Choi, Joon-Weon,Choi, Don-Ha,C IOS Press 2007 Biofactors Vol.29 No.2
<P>Previously we reported that cadalene extracted from Zelkova serrata inhibited lung tumorigenesis in mice. However, the precise mechanism has not yet investigated. Here, we examined the effects of cadalene on signal pathways important for apoptosis, cell cycle, and protein translation in lung cancer cells. Our results showed that cadalene suppressed the expression of Akt and its phosphor-forms through controlling PI3K and PTEN. Cadalene also induced apoptosis through facilitating pro-apoptotic protein expression. In addition, cadalene caused cell cycle arrest and decreased mTOR-mediated protein translation. Taken together, cadalene may be developed as a lung cancer therapeutic agent in the future.</P>