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      • KCI등재후보

        Population Dynamics of Zacco platypus in Gap-Stream and Its Relation with Water Quality

        Shin, Young-Eun,Choi, Ji-Woon,An, Kwang-Guk The Korean Society of Limnology 2009 생태와 환경 Vol.38 No.1

        This study was to provide basic data for aquatic ecosystem research using fishes. Field sampling was carried out at five selected sites of Gap Stream, and fish samples, especially for a selection of sentinel species were collected three times in June, September, and October 2007. We analyzed total length distribution of Zacco platypus in relation with the season and the sampling sites, and then compared with total body weight, condition factor (K), and age distribution of the fish. The fish population data were compared with physico-chemical water quality, obtained from the Ministry of Environment, Korea. Water quality analysis showed a significant nutrient enrichment, based on total nitrogen (TN) and total phosphorus (TP), and organic matter pollution, based on biological oxygen demand (BOD) and chemical oxygen demand (COD) in the Site 5, which is directly influenced by wastewater disposal plant (WDP). Population analysis of the sentinel species showed that the total number of individuals, age distribution, and the population size-structure were influenced by the effluents from the WDP, and that reproductive failure of young-age population were evident in Site 5. According to the relation analysis of total weight to K, the disturbed population was mainly attributed to combined effects of habitat modifications and chemical degradations. Regression analysis of K values against water quality parameters showed significant (p<0.05) positive relations with nutrient and organic matter contents. Our data suggest that the population structure using a sentinel fish species reflected the ambient water quality in the stream and that diagnosis of aquatic ecosystem health using Z. platypus population may be practical for water resource and ecosystem conservations.

      • GG-38 : Minimal invasive surgery (LESS) for huge cystic adnexal tumors in whole abdomen

        ( In Young Choi ),( Ji Hye Lee ),( Mi Hyun Park ),( Ji Kwoun Park ),( Jeong Kyu Shin1 ),( Won Jun Choi1 ),( Soon Ae Lee ),( Jong Hak Lee ),( Won Young Paik ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

        Laparoendoscopic single-site surgery (LESS) is helpful if not an evidence of suspicious malignancy in huge adnexa tumors. This approach might be reasonable alternative to conventional laparoscopic surgery. We report two cases with LESS for huge cystic adnexal tumors in whole abdomen. A 58 years old multigravida woman in menopause underwent removal of a huge cystic adnexal mass that occupied her entire abdomen by LESS.(ca.5200ml aspiration) A 15 years old single nulligravida woman had a huge cystic adnexal tumor in whole abdomen reaching to the level of the xyphoid process. A needle through the transumbilical single port was inserted directly under the mass. Subsequently, 8000 ml of cystic fluid was aspirated without spillage.

      • KCI등재

        청장년에서 관찰된 관상동맥의 비죽종성 석회화와 동맥류 : 부검증례보고

        이지신,이영직,박종태 大韓法醫學會 1997 대한법의학회지 Vol.21 No.1

        Coronary artery calcification(CAC) is found frequently in the atheromatous plaques. CAC is known to have increased frequency above 40 years. CAC without evidence of atherosclerosis in young adults is quite rare, however, CAC combined with aneurysms in young adults have been infrequently reported in patients with a past history of a Kawasaki disease in child. We report an autopsy case showing CAC and aneurysm in the absence of macroscopically identified atherosclerotic lesions in a healthy 23-year-old man. The autopsy examination revealed aneurysmal dilatation of the right coronary artery, which was connected with calcified lesion. A calcified lesion of the left anterior descending coronary artery was aslo noted. Microscopically, aneurysmal wall was non-specific except for hyalinized wall and foci of calcification. A striking histologic finding of calcified mass was ring calcification along the wall of the coronary artery. Antecedent Kawasaki disease in the past was suggestive as other reports.

      • KCI등재

        혈관질환 정보관리 시스템

        김동익,김덕경,허세호,이병붕,김용신,김은숙,문지영,도영수,신성욱,김동수,김만태,진재욱,김용신 대한혈관외과학회 2002 Vascular Specialist International Vol.18 No.1

        As medical technology progresses rapidly, there is a rise in the average age along with the Korean dietary lifestyle becoming more westernized, which leads to an increase in the number of vascular disease patients in Korea. Thus, we need to manage the medical information of a disease systematically in order to diagnose and treat constructively. However, since there has been no standardized method of man agement to date, a great deal of information could not be properly utilized nor studied. Therefore, the departments of Cardiology, Radiology and Neurology of Samsung Seoul Hospital recently got together to develop an information management system called the Vascular Data System. This program was developed to be run on win98 O/S, upper Pentium Ⅲ, and upper 128 MB Memory, and its source code is Dephi 4.0. It was configured for the user to set the configurations as well as do a variety of search and analysis. If this program were to be updated continuously, it may be used extensively as well as in various parts of clinical research activities.

      • Farnesol의 合成

        申東守,安志英,金美羅 國立昌原大學校 基礎科學硏究所 1992 基礎科學硏究所論文集 Vol.3 No.-

        5-Bromo-methypent-2-ene(??)를 출발물질로하여 farnesol인(2E, 6E)-3, 7, 11-trimethyldodeca-2, 6, 10-trien-1-ol(??)의 입체선택적 합성을 수행하였다. 5-Bomo-2-methylpent-2-ene (??)을 요오드화 시킨후, 5-lithio-2, 3-dihydrofuran과 반응시켜 5-(4-methyl-pent-3-enyl)-2, 3-dihydrofuran(??)을 얻었다. Dihydrofuran ??를 MeMgI와 Ni(0)-촉매 짝지음 반응시켜 (3E)-4, 8-dimethylnona-3, 7-dien-1-ol(??)을 72%의 수율로 얻었다. 알릴알코올 ??를 4단계를 거쳐 (5E)-6, 10-dimethylundeca-5, 9-dien-2-One(??)으로 변환시켰다. 화합물 ??을 벤젠 용매하에서 dimethylmethoxycarbonylmethylphosphonate와 반응시킨 다음, 에탄올 용매하에서 NaBH₄ 환원시켜서 (2E, 6E)-3, 7, 11-trimethyldodeca-2, 6, 10- trien- 1- ol(??)을 얻었다. Dihydrofuran 4와 MeMgI와의 Ni(0)-촉매 짝지음반웅이 본 연구의 farnsol(??)와 합성에서 중요 단계이다. Stereoselective synthesis of farnesol (2E, 6E) -3, 7, 11-trimethyldodeca-2, 6, 10-tiren-1-o1 (?) , was carried out using 5- bromo-2-methylpent-2-ene (??) as a starting material. After conversion of 5-bromo-2-methyl-pent-2-ene (2) to the corresponding iodide compound, 5-(4-methylpent-3-enyl)-2, 3-dihydrofuran(??) was obtained by alkylation of 5-lithio-2, 3-dihydrofuran with 5-iodo-2-methylpent-2-ene. Ni(0)-catalyzed coupling reaction of the dihydrofuran ?? with MeMgI was proceeded to give (3E)-4, 8-dimethylnona-3, 7-dien-1-ol(??) in 72% yield. The resultant homoallylic alcohol ?? was converted to the (5E)-6, 10-dimethylundeca-5, 9-dien-2-one (??) in 4 steps. Compound 8 was condensed with dimethylmethoxycarbnylmethylphosponate in benzene followed by NaBH₄reduction in EtOH to yield (2E, 6E)-3, 7, 11 -trimethyldodeca-2, 6, 10-trien-1-ol(??), Ni(0)-catalyzed coupling reaction of MeMgI with dihydrofuran ?? was a key step in this synthesis of farnesol(??).

      • 사마귀버섯(Thelephora terrestris) 등 한국산 야생 담자균류 32 종의 렉틴활성

        신가영,이지선,김용주,김빛나,정경수 충남대학교 약학대학 의약품개발연구소 2004 藥學論文集 Vol.19 No.-

        As a preliminary step to develop noble immunomodulatory lectins from Korean basidiomycetes, 32 species of wild mushrooms were collected and their lectin activities were screened using hemagglutination assay. As a result, cold-water extract of 21 species including Thelephora terrestris showed agglutination activities From T. terrestrisa, partially purified lectin fractions, cTTL_(50) and cTTL_(100), were prepared by extraction with cold phosphate-buffered saline (pH 7.2), precipitation with ammonium sulfate and then dialysis Of these. cTTL_(100) was found to be a strong immunomodulating lectin in that it aggluinated BALB/c erythrocytes and sarcoma 180 tumor cells at the concentration of ≥1.95 ㎍/㎖ and ≥39 ㎍/㎖, respectively, and stimulated the peritoneal macrophages to spread at 200 ㎍/㎖.

      • 18S-srRNA 분석에 의한 Acantbamoeba 한국 분리주들의 분류 검토

        신호준,지영진,조명수,김형일,박연희,임경일 아주대학교 의과학연구소 1998 아주의학 Vol.3 No.2

        Acanthamoeba spp. spread in soil, ponds, air and swimming pool, cause a granulomatous amoebic meningitis and amoebic keratitis in human and experimental animals. Their classification had depended upon morphological characteristics and physiological conditions such as thermophilic status and generation times. However, because amoeba species showed the morphological and physiological diversity in isolates, many attempts have been made on identification of Acanthamoeba spp. Restriction fragments length polymorphism (RFLP) analysis of IBS-small subunit ribosomal RNA (srRNA) was an useful tool for classification among morphologically and genetically closely-related species. In this study, 18S-srDNAs of amoebae were amplified by PCR with primer encoding 18S-srRNA gene and digested with restriction endonudeases, and RFLP analysis was applied on classification of Acanthamoeba Korean isolates (YM-4, YM-5 and YM-7), comparing with reference amoebae, A. culbertsoni, A. polyphaga and A. royreba. Trophozoites of six Acanthamoeba spp. had typical acanthopoda, but did not show any morphological differences. Cyst of Acanthamoeba sp. YM-7 was similar to that of A. polyphaga which was designated as group Ⅱ Acanthamoeba. Morphologically other amoebae belonged to group Ⅲ Acanthamoeba. Digestion of 18S-srDNA with six enzymes, Dde Ⅰ, Hae Ⅲ, Hind Ⅲ, EcoR Ⅰ, Rsa Ⅰ and Sph Ⅰ, resulted in various DNA fragments. Using the method of Nei and U (1979) for RFLP analysis, genetic divergence was not observed between A culbertsoni and Acanthamoeba sp. YM-4. Between A. culbertsoni and Acanthamoeba sp. YM-5, genetic distance was 0.070, 0.364 between Acanthamoeba sp. YM-4 and A. polyphaga, and 0.277 between Acanthamoeba sp. YM-7 and A. polyphaga. In comparison with A. culbertsoni and A. polyphaga, Acanthamoeba sp. YM-7 showed genetic distance of 0.330 and 0.154, respectively. Thus, Acanthamoeba sp. YM-7 is a similar species to A. polyphaga. Acanthamoeba sp. YM-5 is a different species from A. polyphaga, but closely-related to A. culbertsoni. Acanthamoeba sp. YM-4 can be classified as a subspecies or a strain of A. culbertsoni.

      • 내구성 증진을 위한 콘크리트 구조물의 표면보강 기술개발

        신영수,김남길 강원대학교 부설 석재복합신소재 제품연구센터 2002 석재연 논문집 Vol.7 No.-

        본 연구에서는 콘크리트 구조물의 내구성을 증진시킬 목적으로 구조물 표면에 2종류의 혼화제를 이용하여 도포 및 침적한 후 그에 대한 강도, 흡수율 및 내약품성에 미치는 요인을 실험적으로 검토한 결과, MMA 및 BP를 도포 및 침적한 시멘트 모르타르의 휨 및 압축강도는 도포회수의 증가 및 침적시간의 경과에 따라 증가하는 경향을 나타냈다. MMA 및 BP를 도포 및 침적한 시멘트 모르타르의 흡수율은 도포회수의 증가 및 침적시간의 경과에 따라 감소하는 경향을 보였다. MMA 및 BP를 도포 및 침적한 시멘트 모르타르의 중량변화는 약액의 종류에 관계없이 침적시간이 경과함에 따라 감소하는 경향을 나타냈다. In this study, the effects of the number of coat and immersion period on strength properties, waterproofness and chemical resistance of coated and immersed cement mortars using two admixture were examined. Test results showed that the flexural and the compressive strengths of the coated and immersed cement mortars increase with increasing number of coat and immersion period. The water absorption of the painted and immersed cement mortars tended to decrease with increasing number of coating and immersion period. In the case of the change of weight and the immersion period for the solutions, a decreasing tendency was shown as the immersion period increases regardless of solution, with a little variation.

      • KCI등재

        Chlorpromazine으로 유발된 음경지속발기증 1례

        신유호,윤도준,이충현,송지영,이상철 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.3

        저자들은 항정신병약물 chlorpromazine 치료 중에 음경지속발기증이 발생하여 수술까지 시행하여 회복된 환자 1례를 체험하였기에 문헌고찰과 함께 보고하였다. 항우울제 trazodone과 함께 chlorpromazine, thioridazine과 같은 항정신병약물이 음경지속발기증의 원인과 관련이 있는 것으로 알려지고 있다. 이러한 약물에 의해 유발되는 음경지속발기증의 기전에 대해서는 알파-아드레날린 차단으로 인한다는 설이 많은 지지를 받고 있다. 치료는 보존적인 치료와 외과적인 치료가 있으며, 외과적인 치료로는 음경해면체 천자와 흡입 세척술 그리고 분로를 만들어 주는 방법들이 있다. 음경지속발기증은 신속한 진단과 치료를 하지 않을 경우 영구적인 발기불능을 초래할 수도 있는 부작용이므로 향정신약물 투여시 이에 대한 관심과 주의를 가져야 할 것이다. Antipsychotic drugs can induce several sexual side effects. Priapism, one of the side effects, is defined as "the persistent abnormal erection of the penis, which usually occurs without sexual desire". There has been an increasing number of reports recently linking the etiology of priapism with psychotropic medication. The drugs known to be associated with priapism are psychotropic drugs such as trazodone, chlorpromazine, thioridazine as well as antihypertensives, anticoagulants and so on. The mechanism of a drug which induces priapism is proposed to be mediated by its alpha-adrenergic blocking effect. Prompt diagnosis and treatment are essential. Priapism is a severe side effect, which can lead to impotence if prompt diagnosis and treatment are not carried out. There are medical and surgical treatments for priapism. The surgical treatments usually involve aspiration, irrigation and the creation of shunt. We report a case of priapism which developed after two years of chlorpromazine treatment. He is a 20-year-old man with schizophrenia. He experienced two times of brief episode of prolonged penile erection before developing intractable priapism. He was treated by shunt operation which showed satisfactory relief of priapism. It seemed by this case that duration and dosage of chlorpromazine were not closely related with priapism. Psychiatrist is needed to give attention to the priapism as one of sexual side effects due to antipsychotics though it is not common.

      • 제분 방법이 다른 찹쌀가루의 이화학적 특성

        신말식,송지영,김정옥 全南大學校家政科學硏究所 1999 生活科學硏究 Vol.9 No.-

        The waxy rice flours were prepared from Sinsunchalbyeo and Hwasunchalbyeo using dry-pin and wet-roller mill, and the properties were investigated. Proximate composition and physicochemical properties of waxy rice flours were similar between two varities, but were different between milling methods. Water binding capacities, soluble carbohydrates and damage starch contents of waxy rice flours were similar between two varities, but were higher in waxy rice flour using wet-roller milling method than using dry-pin milling method. The crystallinities by X-ray diffractorgrams were all A-type. By Scanning Electron Microscope, waxy rice flours were shown large granule surrounded with film like material and the granules were attached with starch granules. The film like material was more tightly bound with granules in flours by dry-pin milling method. Peak viscosity of wet-roller milled flours by Rapid Visco Analyzer(RVA) was higher than that of dry-pin milled ones, but initial gelatinization temperatures were lower in flours by wet-roller milling method.

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