갈근(葛根)으로부터 분리된 puerarin의 항당뇨 효과

임현애,임지선,김정상 경북대학교 농업과학기술연구소 2006 慶北大農學誌 Vol.24 No.-

본 연구에서는 갈근 및 그의 주 이소플라본인 puerarin의 활성을 세포수준에서 분석하였다. 먼저 갈근에 함유된 이소플라본의 양을 분석한 결과, puerarin이 총 이소플라본의 90 % 차지하였다. 다음으로는 puerarin의 항당뇨 활성을 검정한 결과 먼저 탄수화물 및 지방소화효소저해활성에 대해서는 거의 미비한 것으로 나타났으나 인슐린 감수성 및 지방세포의 분화의 유도에 대해서는 농도의존적으로 작용하는 것으로 관찰되었다. 따라서 puerarin은 지방조직내로 포도당의흡수를 촉진함으로서 항당뇨 효능을 발휘하는 것으로 추정된다. In this study we evaluated the anti-diabetic potential of Puerariae Radix and its isoflavone (puerarin) by investigating their inhibitory activities against digestive enzymes, α-amylase, α-glucosidase and lipase and effect on glucose uptake and PPAR γ expression. The activities of carbohydrate digestive enzymes were not inhibited by puerarin. Glucose uptake in differentiated adipocytes was stimulated by puerarin. Furthermore, puerarin enhanced the differentiation of preadipocytes as evaluated by triacylglycerol (TG) accumulation, which is specific for differentiated adipocytes. The effect of puerarin on expression of peroxisome proliferator-activated receptor γ (PPAR-γ) gene, which is associated with obesity and dyslipidemia, was examined by both real-time PCR and reverse transcriptase PCR. The study demonstrated that puerarin increased the expression of PPAR-γ. In conclusion, puerarin showed potential to exert anti-diabetic action by enhancing cellular glucose uptake and thereby TG accumulation in adipocyte tissue.

CDMA2000 1X용 기지국 UP-CONVERTER 개발

임재봉,이지성 국민대학교 생산기술연구소 2003 공학기술논문집 Vol.26 No.-

In this paper, in order to increase the Frequency Allocation (FA) for CDMA-450 base trans ceiver station (BTS) equipment, a TX diversity path, which has 3FAs, has been proposed and developed. The proposed TX diversity path can provide the multi-FA solution to the conventional CDMA-450 base transceiver station system, which has been developed for 1FA service. Issue to be concerned for increasing the FAs is that the distortion and isolation performances should be improved since the increasing the FAs is achieved simply by adding the developed remote module and the HPA to the conventional CDMA-450 base transceiver station system. TX diversity path developed in this dissertation can provide the 3FAs service with output power of 75W by trading off between the noise performance and linearity of the developed diversity path. Furthermore, in order to minimize the required number of the PLL, local frequency source of 385.225MHz has been reused by using the dividing circuit. The proposed method in this dissertation for the increasing the FAs of the conventional CDMA-450 base transceiver station equipments should find applications to the various wireless communication transceiver systems with providing the most cost effective solution.

절삭유와 유기용매에 혼합 폭로된 근로자의 피부질환에 관한조사

임현술,김지용,성열오 동국대학교 경주대학 1993 東國論集 Vol.12 No.-

Cutting oils denature keratin, defat the skin and remove water from it, causing dryness, fissures and frank eczematization. Solvents remove the surface lipid film. Therefore the skin barrier is weakened and the absorption of irritant substances are increased. Saturated hydrocarbons from the solvent and paraffin series are stronger irritant than those from the aromatic series. To evaluate the health effects on skin among cutting oil and solvent exposed workers, self-administrative questionnaire survey was performed on 72 exposed workers and 91 non-exposed workers. The dermatologic examination and patch test were performed on the workers with suspected skin diseases. The results are summarized as follows ; The prevalences of some dermatologic disorders, such as primary irritant dermatitis, dyshidrotic eczema, allergic contact dermatitis and folliculitis were significantly higher among exposed group than non-exposed group(P<0.05). The positive rate of patch test among 16 workers were 6.3% for cutting oil, 18.8% for old solvent, 18.8% for new solventⅠ and 6.3% for new solvent Ⅱ. These results suggest that cutting oil and solvent may be a cause of occupational dermatoses among exposed workers.

브랜드 인지도와 광고가 콘택트렌즈의 착용감과 가격만족도에 미치는 영향

임동규 ; 신상준 ; 한지선 ; 이익한 ; 김진숙 김천대학교 2016 김천대학교 논문집 Vol.36 No.-

The purpose of this research was to analyze the effects of brand awareness and brand advertising on price satisfaction and comfort in contact lens. We did a survey with 200 university students (85 male, 115 female) who have experience of wearing contact lens from April to May in 2015. The brand awareness of contact lens influences to purchasing intention of contact lens, it effects women more than men. Many respondents(53%) replied that the reliability is the most important elements of the advertising. This survey indicates that there is no statistically significant correlation between the brand awareness and advertisement with price satisfaction in contact lens. Therefore we could confirm they have dissatisfaction for prices of contact lens regardless to brand awareness or advertisement. The brand and advertising dependence group have more comfort of contact lens than non-dependence group when they are long time wear of contact lens. Therefore, there is statistically significant correlation between the brand awareness and advertisement with comfort of contact lens. As a result, brand awareness and reliability of advertising influences to purchasing intention of contact lens. But there is no statistically significant correlation with price satisfaction in contact lens. Whereas, brand awareness and advertisement have a statistically significant correlation with comfort of contact lens.

유아학대 예방을 위한 부모교육에 관한 연구

임성혜,이지숙 진주여자전문대학 1997 論文集 Vol.20 No.-

The Purpose of this study is to offer the basis materials necessary for reducing the possibility of induction of child abuse (Parents Education Program for the Child a Abuse Prevention) by grasping the feature of parents to child abuse, the relation between the parents to abuse child and the children through that most of the increasing child abuse is caused at each child's home mainly by the parents. From this study, this study concluded that: The education for parents and expected parents is needed to prevent child abuse. First, The Parenting Training on the desirable up bringing attitude of parents is needed to action feature and problem to be able to appear in the grpwh process of children. Second, Parental self-reliance groups should be formed to help the parents, when they are frustrated on faced with problem, to ease their social estrangment. Therefore, the teachers of nurseries and kindergratens can be trained the knowledge of child abuse and 'parent effectiveness trainning' and 'active parenting today' and 'child's teaching of a behavior' first, then they can teach it to the children s parents. The continuous researchs on the parents education program for child abuse prevention are needed.

Cone-beam CT로부터 제작된 측모 두부계측방사선사진의 정확도 평가

강지영,임성훈,김광원 대한치과교정학회 2007 대한치과교정학회지 Vol.37 No.6

최근 computed tomography (CT) 데이터로부터 실제 두부계측방사선사진 촬영기에서 촬영한 사진과 동일한 확대율을 갖는 두부계측방사선사진을 형성할 수 있는 기능을 갖춘 소프트웨어 (Accurex, CyberMed, Seoul, Korea)가 소개되었다. 이에 본 연구에서는 cone-beam CT (이하 CBCT) 데이터로부터 이 소프트웨어를 이용하여 제작된 측모두부계측방사선사진과 기존의 두부계측방사선사진촬영기로 촬영된 측모 두부계측방사선사진에서 각각 두부계측방사선사진 분석을 시행하여 그 차이를 비교함으로써 소프트웨어를 통해 CBCT로부터 제작된 측모 두부계측방사선사진의 활용 가능성을 평가하고자 하였다. 20명의 교정 환자를 대상으로 CBCT와 측모 두부계측방사선사진을 동시에 촬영하였다. CBCT로부터 제작된 측모 두부계측방사선사진과 기존 방식의 측모 두부계측방사선사진에서 두부계측방사선사진 분석을 시행한 후 두 사진의 계측치의 차이를 paired t-test로 검정하였다. 23개의 계측치들 중, 20개 항목에서는 통계학적으로 유의한 차이가 관찰되지 않았으나, U1-FH, Mx6 to PTV, Maxillomandibular difference의 항목에서는 유의한 차이가 나타났다. 이러한 차이는 CBCT로부터 형성된 측모 두부계측방사선사진의 해상도가 낮아 일부 해부학적 지표를 확인하기 어렵기 때문이며, 임상에서 CBCT로부터 제작된 측모 두부계측방사선사진을 porion, PTV, condylion과 같은 일부 해부학적 지표를 이용하지 않는 SNA, SNB, U1 to SN, IMPA, interincisal angle 등 흔히 사용되는 간단한 측모 두부계측방사선사진 계측에 활용 가능할 것이다. Objective: Three-dimensional approaches for the diagnosis and analysis of the dentofacial area are becoming more popular in accordance with the development of cone-beam CT (CBCT). The purposes of this study were to evaluate the reliability of cephalometric measurements of lateral cephalograms generated from a CBCT image by making comparisons with the traditional digital lateral cephalogram, and to evaluate the possibility of the clinical application of CBCT generated cephalogram images. Methods: Twenty patients whose external auditory meatus could be identified in the CBCT image were selected, and both CBCT and digital cephalograms were taken. Differences between the measurements of both cephalograms were tested by paired t-test. Results: Among the 22 measurements used, only U1-FH, Mx6 to PTV, and maxillomandibular difference showed statistically significant differences between the CBCT generated cephalogram and the digital cephalogram. Conclusions: The results suggest that the CBCT generated cephalogram can be used for some cephalometric measurements not requiring porion, PTV, condylion as a landmark (SNA, SNB, U1 to SN, IMPA, interincisal angle, etc.).

도심 교차로 노면 지표유출수의 초기수질특성에 관한 연구

최상용,고광백,이지영,임세호 한국환경과학회 2006 한국환경과학회지 Vol.15 No.4

열처리를 통한 SNCM220강 권축의 피로특성 향상에 관한 연구

이호성,임지우,임병수 成均館大學校 科學技術硏究所 1997 論文集 Vol.48 No.2

To find out the reason of fracture, specimens were made from the fractured winding shaft and the mechanical properties as well as their microstructures were investigated. Several heat treatments, including caburizing and tempering, were carried out to improve the microstructure, mechanical properties, fatigue crack propagation and rotating bending fatigue characteristics. Through these experiments, following conclusions were obtained, (1) Carburized and tempered specimens showed greatly improved mechanical properties including impact energy, hardness and strength. (2) Crack propagation of the carburized and tempered specimens were faster than that of the original fractured specimens under the same ΔK. However, it was found that, in the early stage, the fatigue crack initiation and growth for the carburized and tempered specimen was more difficult. (3) The fatigue strength of the carburized and tempered specimens increased more than twice than that of the original fractured winding shaft.

길랑-바레 증후군으로 초래된 기립보행불능증:증례보고

이혜림, 이상수, 이성현, 백신혜, 이형석, 신동익, 김지선 충북대학교 의과대학 충북대학교 의학연구소 2012 忠北醫大學術誌 Vol.22 No.1

기립보행불능증 (astasia-abasia)은 양호한 근력과 운동기능을 가지고 있음에도 서거나 걷는 것이 불가능한 것을 말한다. 이것은 흔히 정신적인 질환으로 간주되지만 기질적인 원인들도 보고되고 있다. 보행영역은 근육과 말초 신경 뿐 아니라 전정-소뇌-시상-피질 연결고리의 되먹임 작용에 의한 연계가 필요하다. 우리는 길랑-바레 증후군을 가진 환자에게서 나타났던 기립보행불능증을 경험하였고, 신경염 과 함께 보행 영역 연결의 붕괴가 증상 발생과 연관이 있을 것으로 사료된다.

의료이용통계 일치도에 관한 연구

강성홍,남문희,임지혜 인제대학교 2009 仁濟論叢 Vol.24 No.1

This study was aimed to investigate medical utilization statistics of type and it’s reliability. Second objective is to suggest methods to improγe reliability of patient survey statistics. We collected patient survey data, health insurance data, discharge summary data in 2005 and reliability of medical utilization statistics analyzed using rate of diagnosis. We found correspondence rate of diagnosis among health insurance statistics, patient survey statistics, discharge injury survey statistics was not high. The rate of Mental and behavioral disorders was 5.0% in health insurance statistics, was 2.4% in patient survey statistics, was 1.3% in discharge injury survey statistics. The rate of diseases of the respiratory system was 10.3% in health insurance statistics, was 8.5% in patient survey statistics, was 12.1% in discharge injury survey statistics. Based on these results, to improvement reliability of medical utilization statistics, this study suggest public health statistics system building, performance of patient survey four times yearly, securing expert.