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유용성 도료와 수용성 도료의 유해성 비교에 관한 연구 : 자동차 보수용 도료를 중심으로
권은혜,김광식,오정룡,최정근,정윤석,이유진,김은아,송세욱,정호근 한국산업위생학회 2001 한국산업보건학회지 Vol.11 No.1
The purpose of this study is to substitute water-based painting materials for the current solvent-based ones used in motor-repairing process to minimize the exposure of organic solvents to the painters. This study assessed the exposure of organic solvents to the painters using water-based and solvent-based painting materials and compared compositions, painting processes and the health hazards of the application of these alternative painting materials. The results of this study are as follows. 1. solvent-based painting materials used in motor-repairing process consist of various organic solvents, which consist primarily of toluene, xylene, ethyl benzene, ethyl methyl bezene, trimethyl bezene, ethyl acetate, butyl acetate, methyl isobutyl ketone, 2-ethoxy ethanol, 2-ethoxy ethyl acetate and toluene-2.4-diisocianate and the others. These organic solvents are know as health-hazardous substances. But water-based painting materials are high-solid, low-solvent ones and consist of such two organic solvents as 2-butoxy ethanol and 2-heptanone and the others. 2. The painters using solvent-based painting materials in motor-repairing process are exposed to various organic acetate, methyl isobutyl ketone, trimethyl benzene, 2-ethoxy ethanol, and 2-ethoxy ethyl acetate. But the painters using solvent-based ones are only exposed to 2-butoxy ethanol and 2-heptanone. 3. By using water-based painting materials in stead of solvent-based painting materials containing health-hazardous organic solvents, the exposure of such organic solvents in the painter's breathing zone can be largely prevented. 4. This study recommends water-based painting materials as substitutes for the current solvent-based ones used in motor-repairing process to minimize the exposure of organic solvents to the painters.
Characteristics of East Asian Passiflora virus isolates from passion fruits in Korea
Jeong-Eun Kim,Su-Bin Hong,Hyeon-Yong Choi,Mikyeong Kim,E-Seul Baek,Hae-Ryun Kwak,Min-kyeong Choi,Hyo-jeong Kim,Hyo-jeong Kim,Hyo-Jung Kang,Jong-woo Han,Heon-sub won,Ji-gwang Kim,Hyeon-ju Lee,Chang-Seo 한국농약과학회 2018 한국농약과학회 학술발표대회 논문집 Vol.2018 No.10
Polymorphisms in Apoptosis-Related Genes and <i>TP53</i> Mutations in Non-Small Cell Lung Cancer
Bae, Eun Young,Lee, Eun Jin,Kang, Hyo-Gyoung,Lee, Shin Yup,Jin, Gwang,Lee, Won Kee,Choi, Jin Eun,Jeon, Hyo-Sung,Lim, Jeong Ok,Lee, Eung Bae,Park, Jae Yong The Korean Academy of Medical Sciences 2011 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.26 No.11
<P>Apoptosis plays an essential role in the elimination of mutated or transformed cells from the body. Therefore, polymorphisms of apoptosis-related genes may lead to an alteration in apoptotic capacity, thereby affecting the occurrence of <I>TP53</I> mutations in lung cancer. We investigated the relationship between potentially functional polymorphisms of apoptosis-related genes and <I>TP53</I> mutations in non-small cell lung cancer (NSCLC). Twenty-seven single nucleotide polymorphisms in 20 apoptosis-related genes were genotyped by a sequenome mass spectrometry-based genotyping assay in 173 NSCLCs and the associations with <I>TP53</I> mutations in the entire coding exons (exons 2-11), including splicing sites of the gene, were analyzed. None of the 27 polymorphisms was significantly associated with the occurrence of <I>TP53</I> mutations. This suggests that apoptosis-related genes may not play an important role in the occurrence of <I>TP53</I> mutations in lung cancer.</P>
( Young Eun Joo ),( Hyun Kyung Park ),( Dae Seong Myung ),( Gwang Ho Baik ),( Jeong Eun Shin ),( Geom Seog Seo ),( Gwang Ha Kim ),( Heung Up Kim ),( Hyun Young Kim ),( Sung Il Cho ),( Na Young Kim ) The Editorial Office of Gut and Liver 2013 Gut and Liver Vol.7 No.3
Background/Aims: Atrophic gastritis (AG) and intestinal metaplasia (IM) are premalignant gastric lesions. The aims of this study were to evaluate the prevalence of endoscopic AG and IM and to document the risk factors for these lesions. Methods: In total, 4,023 subjects were enrolled at eight hospitals in Korea. AG and IM were diagnosed by endoscopy. Helicobacter pylori immunoglobulin G antibodies were measured. Results: The prevalences of endoscopic AG and IM were 40.7% and 12.5%. In a multivariate analysis, the risk factors for AG were age groups of 40 to 59 years and >60 years, male sex, positive H. pylori serology, IM, and education below the college level (odds ratio [OR], 2.55, 5.00, 1.38, 1.41, 4.29, and 1.35, respectively). The risk factors for IM were age groups of 40 to 59 years and >60 years, male sex, positive H. pylori serology, AG, having relatives with gastric cancer, education below the college level and consumption of dairy products (OR, 3.16, 3.25, 1.88, 2.17, 3.68, 1.48, 1.47, and 1.40, respectively). Conclusions: A nationwide survey regarding the prevalence of endoscopic AG and IM and their risk factors in Korea supports the hypothesis that endoscopic diagnosis of these premalignant lesions could be helpful to describe a group at high risk for gastric cancer. (Gut Liver 2013; 7:303-310)