The prediction of the tooth size in the mixed dentition for Korean

Moon, Sung-Hwan,Kim, Seong-Oh,Yu, Hyung-Seong,Choi, Byung-Jai,Choi, Hyung-Jun,Lee, Jae-Ho 大韓小兒齒科學會 2006 大韓小兒齒科學會誌 Vol.33 No.2

이번 연구의 목적은 혼합치열기 아동에서 미맹출된 견치와 소구치의 크기를 예측하는데 있어서 한국인에 맞는 방정식을 만들기 위함이다. 미맹출 치아의 크기를 예측하는 것은 혼합치열기 교정 진단과 치료계획 수립에 있어서 매우 중요하다. 미맹출된 견치와 소구치 크기를 예측하는 방법은 몇가지가 있지만 그중에서도 가장 흔하게 쓰이는 것이 모이어의 예측표와 다나카와 존스턴의 방정식이 있다. 하지만 그것들은 백인을 위해서 제작된 것이고 치아 크기는 인종에 따라서 다르다고 알려져 있다. 이번 연구에서는 치아크기를 측정하여 하악 영구 절치의 크기 합과 견치 및 소구치의 크기 합 사이의 상관관계를 구하고 회귀방정식을 이용해서 한국인에 맞는 예측표를 만들었다. 연세대학교 치과대학에 재학중인 178명의 한국 학생(남 108명, 여 70명, 평균연령 21.63)을 대상으로 실험하였다. 영구치의 근원심 폭경을 석고모형상에서 calipers를 이용해서 측정하였다. 성별간의 치아 크기는 차이가 있었다(p<0.05). Correlation coefficient는 0.57에서 0.64의 범위였고, standard errors of the estimates 는 여성에서 0.6으로써 남성보다 우수하였다. r^(2)값은 0.27에서 0.41의 범위를 나타내었다. Estimating the size of unerupted teeth is an essential aspect of orthodontic diagnosis and treatment planning in the mixed dentition. Several methods were introduced and used for the prediction. The most common methods among these would be Moyers probability chart and Tanaka and Johnston equations. These are currently used widely, but they were developed for Caucasians. Because there are clear racial differences in teeth size, the objectives of this study were to produce correlation coefficients between the combined mesiodistal widths of the permanent mandibular incisors and those of the canines and premolars for each quadrant, and prediction tables with regression equations, specifically for Korean. 178 young adults (70 women, 108 men, mean age 21.63 years) were selected from the College of Dentistry, Yonsei University, Seoul, Korea. The mesiodistal crown diameters of the permanent teeth were measured with calipers. Significant sexual dimorphism was found in tooth sizes. The correlation coefficients between the total mesiodistal width of the mandibular permanent incisors and those of the maxillary and mandibular canines and premolars were found to be between 0.52 and 0.64. The standard error of the estimatation was better (0.60) for women and the r^(2) values ranged from 0.27 to 0.41 for both sexes, Prediction tables were prepared for Korean. This study showed larger canine and premolar diameters than Tanaka and Johnston's and Moyers' studies which might be due to the racial differences. Further investigations with a larger sample size will be needed for more representative data on the Korean population.

급박 하지 허혈증에 대한 비수술적 치료의 장기 추적 결과

최재영,손민수,이길연,이상목,고석환,홍성화,윤층,오수명,박호철 대한혈관외과학회 2003 Vascular Specialist International Vol.19 No.1

농산물의 풀질인증 단계별 소비자가치 측정

최태길,김태균,조재환 한국농업정책학회, 한국축산경영학회 2000 농업경영정책연구 Vol.27 No.1

This study used a dichotomous-choice contingent valuation method to measure consumer's value of quality certificated lettuce. Consumers were willing to pay more than the current price of regular lettuce for quality certificated lettuce. This value is attributed to the safety of quality certificated lettuce in comparison with regular lettuce. Findings suggest that the consumers put substantially high value on safe food, such as high quality certificated lettuce.

뇌기능 분화가 논리적 사고력과 자연과 단원별 성취도에 미치는 영향

崔在煥 大邱敎育大學校 科學敎育硏究所 1993 과학·수학교육연구 Vol.17 No.-

Methotrexate 치료를 받고 있는 활동성 류마티스 관절염 환자에서 etanercept의 유효성과 안전성에 관한 연구

최병렬,강태영,정청일,이혜순,엄완식,김태환,전재범,유대현,배상철 대한내과학회 2004 대한내과학회지 Vol.66 No.5

목적 : 류마티스 관절염을 앓고 있는 한국인 중에 기존 DMARDs로 치료 실패하였고, 고정용량의 MTX를 복용하고 있는 환자들에 있어서 etanercept의 유효성과 안전성을 평가하고자 하였다. 방법 : 기존 DMARDs로 치료 실패한 활동성 류마티스 관절염 환자 76명을 대상으로 하여 단일군, 공개시험을 하였다. 대상 환자들은 고정용량의 MTX를 복용하면서 etanercept 25 mg을 1주일에 두 번 피하 주사하였으며 12주간 투여하였다. 유효성은 ACR 20, ACR 50,조조강직 시간으로 평가하였고, 약제의 안전성은 이상반응 등으로 평가하였다. 결과 : 대상 환자는 총 76명으로 평균 연령은 45.2세, 남자 5명, 여자 71명이었다. 84.4%인 54명이 12주째에 ACR 20을 만족하였고, 53.1%인 34명이 12주째에 ACR 50을 만족하였다. 조조 강직 시간은 치료 전 203.3분에서 치료 12주째 42.6분을 평균 74.5% 호전되었다. 가장 흔한 이상반응은 주사부위 반응이었다. 이외에도 상기도 감염, 오심, 안면부종 등이 발생하였으나 심각한 부작용은 없었다. 결론 : etanercept는 효과적이고, 안전한 류마티스 관절염 치료 방법이며 특히 MTX치료에도 불구하고 활동성인 류마티스 관절염에 기대되는 치료라고 할 수 있다. Background : This study was performed to investigate the efficacy and safety of etanercept in active rheumatoid arthritis patients with stable dose of methotrexate in Korean. Methods : In a 12 week, single arm, open trial, we assigned 76 patients with active rheumatoid arthritis who had an inadequate response to disease-modifying antirheumatic drugs. Patients received twice-weekly subcutaneous injections of etanercept 25 ㎎ while containing to receive methotrexate at a stable dose of 7.5~25 ㎎ per week. The clinical response was defined as the percent improvement in disease activity according to the criteria of the American Collage of Rheumatology (ACR) at 12 weeks. Results : Etanrecept led to significant improvements in disease activity and was safe and well tolerated. At 12 week, 84.4% of the patients receiving 25 ㎎ of etanercept achieved a 20% ACR response, and 53.1% of those receiving etanercept achieved a 50% ACR response. The most common adverse event was injection-site reaction. Other advanse events were upper respiratory infection, nausea, and facial edema, but there were no serious adverse events associated with etanercept. Conclusion : In active rheumatoid arthritis patients, etanercept was safe, well tolerated, and provided rapid clinical improvements.

PCR과 SDS-PAGE를 이용한 젖산균의 분류

최동훈,이중림,민승기,박종환,김해영,조재선 慶熙大學校 1998 論文集 Vol.27 No.-

Strain type of lactic acid bacteria was analysed by PCR and SDS-PAGE. PCR allows the rapid and specific detection of lactic acid bacteria using primers based on 16S rRNA gene-sequences. The analysis of protein pattern on SDS-PAGE can be used to determine the differences among the same or similar species of lactic acid bacteria. Therefore, the complementary use of PCR and SDS-PAGE method is one of simple way to classify the lactic acid bacteria and to compare with genetic analysis.

산과 염기의 개념분석과 오인에 관한 연구

崔在煥 大邱敎育大學校 科學敎育硏究所 1992 과학·수학교육연구 Vol.16 No.-

The purpose of this study is pesultionship Between the Cognitive of child and conceptions about Acid and base. The results were as follows. 1. The cognitive level of most 5th elementary school student in korea in general, sty in the concrete operational stage, pre-operational stage and only one pupil have reched formal operational stage. 2. The degree of understanding of conceptions about acid and Base showed the acid higher achivment than the base.

한 · 일 중재법상 중재판정의 비교법적 고찰

최석범,정재우,김태환 韓國仲裁學會 2006 중재연구 Vol.16 No.1

The parties in the trade can have full autonomy and can resolve disputes independently, impartially and without delay by selecting arbitration by agreement. Korea and Japan had revised their Arbitration Laws to incorporate as many provisions of the 1985 UNCITRAL Model Law as possible. Japan had amended its century-cld arbitration law, becoming the 45th country to adopt the UNCITRAL Model Law on International commercial arbitration. New Arbitration Law was enacted as Law No.138 of 2003 and effective on March 1, 2004, is applicable to both national international arbitration. Korea had amended its arbitration law on December 31, 1999 and its New Arbitration Law incorporates the most of the 1985 UNCITRAL Model Law as Japan. Arbitration must be popular in resolving international commercial disputes in Northeast Asian bloc in order to increase the volume of intra-trade in the Northeast Asian bloc. But in order for the parties to make use of arbitration in the bloc, the arbitration laws of nations in the bloc must have similarity and unification. As Korea and Japan playes important roles in the bloc, both nations's arbitration laws must be studied in view of similarity and difference to unify both nations' arbitration laws by way of showing an example. Therefore, this paper deals with both nations' arbitration laws in view of comparative law to unify their arbitration laws and Northeast Asian Nations' arbitration laws.

발프로산나트륨과 페니토인과의 약물상호작용

최준식,유재신,박용채,이진환 朝鮮大學校 1997 藥學硏究誌 Vol.18 No.2

This study was attempted to investigate the pharmacokinetic interaction between sodium valproate (4. 8. 16 ㎎/㎏. i.v.) and phenytoin (4 ㎎/㎏. i.v) in rabbits. The plasma concentration and area under the curve (AUC) of phenytoin were increased significantly (p<0.05. p<0.01) when coadministered with sodium valproate (4. 8. 16 ㎎/㎏) in rabbits. The volume of distribution and total body clearance of phenytoin were decreased significantly (p<0.05. p<0.01) when coadministered with sodium valproate (8. 16 ㎎/㎏) in rabbit. From the results of this experiment. it is desirable that dosage regimen of phenytoin should be adjusted and therapeutic drug monitoring should be performed for reduction of side or toxic effect when phenytoin will be coadministered with sodium valproate in clinical use.

운동에 따른 MDA 및 SOD, GPx, CAT와 면역기능의 변화 고찰

최종환, 한재영 忠北大學校 平生體育硏究所 2013 平生體育硏究所 論文集 Vol.25 No.-

1. The change of MDA in accordance with exercise Many researchers at home and abroad told that MDA concentration tends to be low significantly if we do regular exercise in the long term. This means the adaptation of defence mechanism of antioxidants caused by moderate exercise. 2. The change of SOD, GPx, and CAT in accordance with exercise. The increase of SOD will be expected if a regular exercise in the long term is implemented regardless of a type, intensity, and time of the exercise. Meanwhile, at preceding researches, CAT showed significant change in high intensity exercise. It seems that GPx is significant when high intensity exercise is done and it is more activated by long-term and long-time exercise. 3. An intake of antioxidants and the change of SOD, GPx, and CAT in accordance with exercise It is reported that an intake and exercise of Vitamin C and E enhances resistiveness against lipid peroxide, and endurance exercise capacity significantly in many researches. Also, an intake of antioxidants and exercise do not have an effect on the activation of SOD through an intake of Vitamin, but high intensity exercise and an intake of Vitamin enhance the activation of SOD, and CAT. 4. The change of immune system in accordance with exercise and an intake of antioxidants It is reported that an intake of antioxidants and exercise have an effect on immune system. It is also reported that the medium intensity exercise enhances the increase of immune system, but high intensity exercise enhances the long-term increase of it. Meanwhile, if the period for an intake of antioxidants is short, antioxidants do not affect immune system. Also, independent treatments of antioxidant vitamins is limited about the improvement of immune function. 5. Suggestions The excessive exercise increases antioxidant enzymes like SOD, CAT, and GPx in skeletal muscles, heart, and livers. The threshold value and magnitude of exercise are different in accordance with enzymes and tissues. The validity of these findings are recognized by studying the response of free oxygen radicals in various tissues. However, mechanism that antioxidant enzymes are activated in short term during exercise is not acknowledged so it may be necessary that a research should be implemented about how the quick activation of antioxidant enzymes effectively responds to a cell damage from peroxide lipid. Also, the treatment of antioxidant vitamins enhances the activation of antioxidant enzymes and immune function, but a research about proper intake and period of antioxidant vitamins in addition to exercise in order to block the oxidative damage is necessary in the following research. Meanwhile, Methionine is the essential amino acids for growth and maintenance of cellular tissues. Jo Soo Yeal(1997) reported that an intake of Methionine improved the activation of SOD significantly. It is also reported that sulfhydryl group, one of metabolites of Methionine, acts as a direct remover of free radical, maintains Glutathione concentration constantly, and works as the disposition of glutathione peroxidase to protect cells from lipid peroxidation.(Shwa, et al., 1981) Methionine is the essential amino acids to protect cells from the reactive oxygen as a role of antioxidants. Until now, comparative studies about Methionine and existing antioxidants in relation to exercise have not been sufficient. Therefore, it may be meaningful that the effect on Methionine and existing antioxidants in relation to the relation of exercise and antioxidant enzymes in the following research.