Quinlolone 유도체 국소도포에 의한 좌창치료의 임상적 연구

권철욱,노영석,김재홍,조소연,강형철,함정희 大韓臨床藥理學會 1994 臨床藥理學會誌 Vol.2 No.2

감성관련 연구논문 데이터에 기초한 감성공학연구의 방향 조사

정재욱 울산대학교 2001 조형논총 Vol.4 No.1

최근들어 '감성공학'이라는 하나의 틀 속에서 심리학이나 인간공학, 인지과학 등을 중심으로 한 감성의 해석 및 그 응용에 관한 연구가 학제적으로 행하여지게 되었지만, 학문으로서의 그 체계화는 아직 이루어지지 않고 있다. 따라서 본 연구에서는 감성공학의 학문영역으로서의 틀을 파악하고, 그 체계를 명료하게 하는 것과 함께, 이후 감성공학의 방향성을 모색하는 것을 목적으로 하였다. 이것을 위해, 일본학술회의 감성공학소위원회(日本學術會議 感性工學 小委員會)의 1996년도 문부성 과학연구비 프로젝트로 수집된 감성관련논문을 데이터로 활용하여 분석을 하였다. 수집된 데이터를 수량화Ⅲ류와 크러스터 분석을 이용하여 키워드의 유사성(類似性)에 의한 분석을 행한 결과, 감성관련논문은 주로 감성의 계측이나 해석등을 중심으로 한 기초영역에 편중되어 있는 것을 알게 되었다. 얻어진 키워드 및 논문의 2차원 분포공간(分布空間)을 구성하는 축(軸)은 감성관련연구의 "방법(方法)"과 "대상(對象)"으로 각각 그 해석이 가능하였다. 연구의 "방법"축에 대하여는, 컴퓨터에 의한 '디자인 지원시스템'이나 '방법론' 등과 같은 감성의 논리적 지원(Logical Support)에 관한 논문과, '감성대행'이나 '자연언어관리' 퍼지이론에 의한 애매한 '화상검색' 등의 감각적 지원(Sensitive Support)에 관한 논문으로 크게 나뉘어 지고 있었다. 그리고 연구 "대상"축을 기준으로 고찰하여 보면, 심리, 생리 등의 소프트(Soft)적인 면과, 물리적인 패턴, 색채 등의 하드(Hard)적인 면을 대상으로 한 논문으로 나뉘어져서 분포하고 있음을 확인할 수 있었다. 감성을 "외부자극에 의한 감각(感覺)에서 정동(情動)에 이르기까지의 심리적 반응"이라는 시점에서 이상의 감성공학연구의 동향을 볼 때, 금후의 감성공학은 보다 인간의 고차감성(高次感性)의 해명과 그 응용에 관한 연구로 나아갈 것이 예상된다.

음에 있어서 감성자극요소의 추출과 그 상호관계에 관한 연구

정재욱 한국기초조형학회 2003 기초조형학연구 Vol.4 No.1

기능성을 따르는 형태보다는 인상(印象)을 중요시하는 ‘감성지향’의 디자인프로세스에 있어서는 감성정보의 처리과정이 필요하게 된다. 더욱이 멀티미디어기능 제품의 보급과 함께, 지금까지의 ‘형태’라는 시각정보만이 아니라 ‘음(音)’이라는 청각정보 또한 디자인개발 프로세스 속에서 고려되어야 할 시기가 왔다고 생각한다. 본 연구에서는 청각정보의 하나인 전자음의 감성자극요소를 추출하고, 그 각 요소간의 감성반응유발의 규칙성을 명확히 하는 것을 연구목표로 하였다. 일반적으로 음의 감성반응을 의미하는 ‘음색(音色)’에 대하여, 음향공학 등에서는 주파수변화량에 근거한 인식, 판별 등, 이성적(理性的) 논리에 관계되는 물리적 요소를 대상으로 하고 있는 것이 많지만, 본 연구에서는 감성반응에 관계되는 물리적 요소를 그 대상으로 하고 있다. 실험에서는 인간감성의 가장 기저(基底)라고 말하는 ‘쾌(快)’ ‘불쾌(不快)’를 기준척도로 하여, 신서사이즈에 내장되어 있는 전자합성음 49개를 18명의 피험자에 들려주어 감성 반응치를 얻었다. 그 후 얻어진 데이터를 종속변수로 하고, 신서사이즈의 조작 파라메터의 39항목을 독립변수로 하는 중회귀분석을 행한 결과, 각 카테고리의 사이에는 감성반응을 유발시키는 요소로서의 규칙정이 명확히 존재한다는 것을 알 수 있었다. 후속연구로서는 본 연구에서 설정한 전자음 카테고리의 범용성에 대한 검증 실험을 행할 예정이다. The steps processing a kamsung information is necessary in the 'kamsung-oriented ' design process which emphasizes and impression rather than a shape. As a functionally-oriented multimedia processing, which is confined to the visual information, to an auditory information system. This study aims to extract the elements of an electronic sound, which is one of the auditory information, stimulating the kamsung. The interaction rule among the elements is clarified, too. The acoustic science deals with the tone color, the kamsung reaction to a sound in terms of physical properties having something to do with a cognizance based on a logically. This study is interested in the physical elements being associated with the kamsung reaction. In the experiment, the reaction data of 18 people to the 48 synthesized electronic sound is gathered. The data is based on the pleasure, displeasure, which are the basic kamsung of a human being. The multiple regression, whose dependent variable and independent variables are the data and 49 parameters of the synthesized electronic sound, is applied. The result shows that there exists a regularity among each category. The next study will be the general applicability of the categories used in the experiment with the electronic sound.

예화 중심 수학 수업의 효과 분석

정재욱, 최창우 대구교육대학교 과학교육연구소 2014 과학·수학교육연구 Vol.37 No.-

고혈압과 당뇨병이 허혈성 뇌혈관질환의 위험인지로서의 Lipoprotein(a)에 미치는 영향

박정욱,박성경,이정욱,김영인,김용재,이광수,김범생 대한신경과학회 1996 대한신경과학회지 Vol.14 No.1

Transarticualr portal를 이용한 주관절의 관절경술

김성재,박인섭,김주영,정재훈,류상욱,천용민 대한견.주관절학회 2003 大韓肩.주關節學會誌 Vol.6 No.2

관상동맥조영술중 비이온성 조영제 Iodixanol (Visipaque®)에 의해 발생한 아나필락시양 반응 1예

최원욱,조정수,김성철,김상훈,안영수,최재웅 대한내과학회 2004 대한내과학회지 Vol.66 No.1

흉통을 주소로 내원한 45세 남자에서 관상동맥조영술 중 비이온성 조영제에 의하여 아나필락시양 반응이 발생한 증례를 경험하였기에 보고하는 바이다. Radiocontrast agent infusion is the most common cause of non-IgE mediated anaphylactoid reaction in the modern medical procedures. The newer lower-osmolar nonionic contrast agents cause significantly lower adverse reactions than the high-osmolar ones. However, anaphylactoid reaction to nonionic contrast agent can cause life-threatening events and even death has been rarely reported. Iodixanol (Visipaque®) is a nonionic, dimeric contrast agent, which is currently used in cardiac catheterization. Here we report a case of anaphylactoid reaction to Iodixanol, a nonionic radiocontrast agent, during cardiac catheterization. A 45-year-old male patient underwent cardiac catheterization for evaluation of substernal pain during exercise. Five minutes after this contrast injection to the left coronary artery, he complained itching and dizziness. Subsequently, generalized urticaria, cyanosis and hypotension were developed. His coronary angiogram showed normal findings. He was treated with intravenous fluids, intravenous diphenhydramine, sucutaneous epinephrine and sympathomimetics and one hour later he recovered. This case suggests that anaphylactoid reaction to a radiocontrast media, iodixanol, should be considered in the list of differential diagnoses for cardiopulmonary arrest during cardiac catheterization.

한국 일부지역의 이주근로자의 근로조건과 산업재해실태 조사

최재욱,김정아,김해준,박종태 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.1

This study was conducted to evaluate and to recognize the status and the problems of working conditions, and industrial accidents for migrant workers in a group of 342 who lives in Ansan area, Kyunggi province. By the questionnaire written by 5 languages(English, Bangladesh, Indonesian, Chinese and Korean), the informations of socio-demographic factors, occupational conditions of engaged company and general & occupational health status were obtained from June, 1st to July 30th, 1998. We used the ANOVA to examine differences of working hours, days and average monthly wages between overseas industrial trainee and illegal migrant workers, and by using logistic regression, odds ratio of general risk factors for industrial accidents in migrant workers were calculated. The results obtained were as follows: 1. The major distribution of nationals were from Philippine, Indonesia, Bangladesh and China(92.1%), and the most of subjects were man(78.9%) and over high school graduate(81.9%). 2. Most migrant workers worked at small scale companies under 50 employees, and engaged in dye·textile·clothing·leather industry. The average working hours were 59.9 hours per week in overseas industrial trainee, 64.9 hours in illegal migrant worker respectively. 3. Trainees have transferred to another company for 1.89 times, and workers who have changed qualification from trainee to illegal status were 3.09 time, and illegal workers moved 2.36 times. The major portion of reason to move to another company were low salary and overdue salary. 4. Trainees, workers who have changed position from trainee to illegal status, and illegal workers knows 62.27%, 42.31%, and 20.45% in each about legal documentation for foreign industrial trainees in Korea "Regulations for protecting and managing of foreign industrial trainees in Korea " published on March 1995. Additionally, trainees and illegal workers have experienced medical examination by 52.3% and 18.2% respectively. 5. Industrial accident condition from Jun. 1st, 1997 to Dec. 31th, 1997 were as follows : in case of frequent rate, trainees and illegal workers were 30.04, 23.78 each, and 8.6%, 7.4% for industrial accident rate respectively. 6. The most common causes and types of industrial accident were inappropriate motions of body and abrasion, and body sites most vulnerable to injury were the hands and fingers. The results suggest that working status and industrial accidents of migrant workers are very poor in Korea. Therefore, occupational safety and health policy aimed at migrant workers are needed to protect the migrant workers.

Trehalose의 노화 억제 효과

박정욱,정한모,송재철 울산대학교 2000 생활과학논문집 Vol.2 No.1

시차주사열량기와 색도계를 이용하여 Trehalose의 가래떡 노화에 미치는 영향을 검토하였다. 가래떡의 노화정도는 저장온도와 무관하게 경시적으로 증가하였는데 Trehalose가 노화를 억제하는 것으로 나타났다. 특히 저온에서 노화가 실온보다 심하게 일어났으며 저장초기에 저장온도에 대한 영향이 큰 것으로 나타났다. 그리고 L*값은 실온저장(25℃)시 냉장저장(4℃)의 경우보다 시간에 따른 변화가 컸으며, 냉동보관시 a*값은 저장 1일째 까지는 변화가 없다가 5%를 첨가한 가래떡을 실온에서 저장한 경우에는 가장 낮은 a*값을 나타내었다. b*값의 경우에는 Trehalose 첨가량과 저장온도에 따라 크게 변하지 않았다. 색깔안정화의 효과는 Trehalose 첨가농도가 증가할수록 큰 것으로 나타났으며, 특히 냉장보관시에 효과가 두드러지는 것으로 관찰되었다. This studies were investigated to provide the influence of trehalose on retrogradation of Korean rice cake by differential scanning calorimeter and tristimulus values of CIE color Croma Meter. Having no connection with storage temperature, degree of retrogradation of Korean rice cake was increased with storage time. Degree of retrogradation of Korean rice cake was decreased in case of addition of trehalose to the Korean rice cake paste. Degree of retrogradation of Korean rice cake stored at low temperature(4℃) was higher than that of Korean rice cake stored at room temperature(25℃). In particular, degree of retrogradation of Korean rice cake was shown to be clearly influenced by storage temperature at the beginning of storage. The value of L of Korean rice cake at room temperature was indicated to be significantly changed compared with that of Korean rice cake at low temperature. The value of a of Korean rice cake was not changed until one day of storage, and shown to be minimized in storage at room temperature(25℃) in case of addition of 5% trehalose to the paste of Korean rice cake. The change of b value in general was not significantly observed even if storage temperature and amount of trehalose have been variable. However effects of trehalose in color stability of Korean rice cake was remarkably exhibited in storage at low temperature(4℃).

몇가지 작물중 침투성 살충제 Carbofuran의 잔류량 분석

이재구,최신종,경기성,안기창,권정욱 충북대학교 농업과학기술연구소 1999 農業科學硏究 Vol.16 No.-

In order to ascertain the safety of the systemic insecticide carbofuran - treated crops. garlic, peanut and potato were collected randomly from markets near the major producing farms and analyzed for the residues of carbofuran and its main metabolite, 3-hydroxycarbofuran. The in vitro metabolism of carbofuran in phosphate buffer extracts of the crops was investigated. The results obtained were as follows. 1.The recoveries of carbofuran and 3- hydroxycarbofuran from the spiked samples were 92~ 100% in all samples. The detection limit and minimum amount of carbofuran detected were 0.02ppm and 0.1ng, and those of 3-hydroxycarbofuran 0.06ppm and 0.3ng, respectively. 2.Two mature garlic samples out of 20 contained 0.13 and 0.07ppm of carbofuran, respectively, showing a detection frequancy of 10%. The residue level was less than the maximum residue limit(0.5ppm) set by the health authorities in Korea. Only one mature garlic sample out of 20 contained 0.13ppm of 3-hydroxycarbofuran. 3.The residues of carbofuran and 3-hydroxycarbofuran in the immature garlic, peanut and potato samples were less than the detection limits. 4.The application of carbofuran to the fields of garlic, peanut and potato would be safe, considering that the estimated maximum acceptable daily intake of carbofuran from garlic was 0.0007mg which is 0.13% of the maximum acceptable daily intake(0.55mg) . 5.Carbofuran was hydrolyzed in vitro mainly to carbofuran phenol(m/z 164) in phosphate buffer extracts of the three crops in contrast to the major oxidative metabolism in situ. The amount of the metabolite increased with the incubation time.