간세포암의 고주파 열치료 후 천자침 경로를 통한 전이 1례

조영완,박석주,진한영,김준영,이재익,강명주,박정하,윤정희,박성재,지삼룡,이연재,이상혁,설상영 인제대학교 2006 仁濟醫學 Vol.27 No.-

Radiofrequency ablation(RFA), as a form of minimally invasive therapy for hepatocellular carcinoma, has become an important treatment modality. Because of limitation of surgery, RFA has become standard therapy for hepatocellular carcinoma in some situations. But there are some complications of RFA such as bleeding, infection, hematoma, adjacent organ thermal damage including intestinal perforation, needle track seeding, and so on. There are few reports in the literature that systematically evaluate the incidence of needle tract seeding and its associated risk factors. And only 2 cases of needle tract seeding of hepatocellular carcinoma after RFA were reported in Korea. We report a case of needle tract seeding of hepatocellular carcinoma after RFA.

Effect of Developmental Lead Exposure on the Expression of Hippocampal NMDA Receptor Subunit mRNA

Kim, Tae-Wan,Chung, In-Sung,Bae, Jae-Hoon,Shin, Dong-Hoon,Lee, Mi-Young,Kim, Joon-Sik 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

목적: in vivo 및 vitro에서 해마 신경세포의 발생단계별 NMDA 수용체 아단위 mRNA 발현에 대한 연 폭로 영향을 알아보고자 하였다. 방법: 흰쥐 해마 신경세포의 발생단계별 NMDA 수용체 NR2A, NR2B 아단위 mRNA 발현에 대한 연의 영향은 정상군과 연 폭로군의 출생 후 7일, 14일, 22일 흰쥐의 해마에서 in situ hybridization으로 mRNA 발현 정도를 densitometer로 측정하여 비교하였고, 연과 NMDA 의 세포독성은 해마 신경세포 일차배양 후 도립현미경을 이용한 형태학적인 관찰과 LDH 활성도를 이용하여 측정하였다. 결과: 연 과 NMDA 에 의한 세포독성에 대한 in vitro 실험에서 형태학적 소견과 LDH 활성도에서 해마 미성숙 신경세포와 성숙 신경세포사이의 차이가 있었으므로, 연과 NMDA 독성효과는 해마 신경세포의 발달 단계에 따라 차이가 있다. 정상군의 해마에서의 NR2A mRNA 발현은 출생 후 연령이 증가함에 따라 점진적으로 증가하였으나, NR2B mRNA 발현은 출생 후 연령이 증가함에 따라 점진적으로 증가하였으나 NR2B mRNA 발현은 연령의 증가에 따른 변화가 없었다. 연 폭로에 희한 NR2A mRNA 발현은 유의하게 감소하였으나(p<0.05), NR2B mRNA 발현은 변화가 나타나지 않았다. 만성적 연 폭로는 NR2A를 포함하는 NMDA 수용체를 감소시킬 수 있음을 알 수 있다. 결론: 연은 해마신경세포의 발생단계에서 NMDA 수용체 아단위 특히 NR2A mRNA 발현의 변화를 야기하여 시냅스 신호 전달에 영향을 나타냄을 알 수 있었다. Hippocampus

지역주민의 삶의 질에 관한 주관적 의식 분석

이지은(Lee, Ji-Eun),이재완(Lee, Jae-Wan) 한국지방정부학회 2014 지방정부연구 Vol.18 No.1

이지은(Lee, Ji-Eun), 이재완(Lee, Jae-Wan) 본 연구의 목적은'삶의 질'에 대한 지역주민의 인식을 유형화하고 분석하는 데 있다. 지역주민의 삶의 질에 관한 주관적 인식을 분석하기 위해 Q방법론을 활용하였다. 지역주민을 대상으로 한 인터뷰 및 선행연구 검토를 통해 Q진술문을 작성하였고, P샘플은 서울시에 거주하고 있는 지역주민 40명을 대상으로 하였다. 분석 결과, 삶의 질에 대한 주민인식은 ① 기본적 요건 지향, ② 물질적 요건 지향, ③ 비물질적 요건 지향으로 유형화되는 것으로 나타났다. 본 연구는 삶의 질에 관한 인식이 지역주민마다 다를 수 있으므로, 지방자치 수준에서 숙의민주주의를 실현할 수 있는 공론의 장을 마련할 필요가 있다는 점을 시사한다. 지방정부가 지역주민들의 삶의 질을 향상시키는 정책을 수립할 때 다양한 주민들의 인식과 의견이 반영될 수 있도록 하여야 할 것이다. The objective of this study is to classify and analyze citizens' perceptions on 'quality of life'. In order to examine quality of life as perceived by citizens, Q-methodology was used. A set of Q-statements was constructed with reference to field interviews of citizens and literature review of the precedent study, and it was rated by 40 citizens residing in Seoul. The results of this study revealed that citizens' perceptions of quality of life could be classified in terms of three perspectives: 1. Basic conditions orientation, 2. Material conditions orientation, and 3. Non-material conditions orientation. Based on the analysis results, this study suggests that as citizens' perceptions of quality of life can be diverse, there is a need to develop a public sphere where deliberative democracy would be realized and advanced at local government level. By creating and developing public spheres, local governments would be able to take citizens' perceptions and opinions into account better when establishing policies for improving citizens' quality of life.

전해산성수를 이용한 새로운 내시경 소독 시스템(Cleantop WM-1??)의 소독효율

이준행,이풍렬,송재훈,이남용,임윤정,장재권,김영호,김재준,백승운,이종철,최규완 대한감염학회 2001 감염 Vol.33 No.2

Background : Electrolyzed acid water (EAW) is a new liquid chemical germicide containing a mixture of oxidizing species and prepared by mixing a small amount of salt with tap water in an electrolyzer. We attempted an in-use evaluation of the high-level disinfection capability of Cleantop WM-1□, a new endoscope reprocessing system using EAW. Methods : Forty-seven flexible endoscopes were randomly collected just after upper endoscopic examinations and were disinfected using Cleantop WM-1□. Parts of the endoscopes without contact to EAW were disinfected with 75% ethyl alcohol. Immediately after the disinfection procedure, samples were taken from the biopsy channel (S-1), tip of the insertion tube (S-2), the umbilical cord (S-3), and the angulation knob (S-4). Results : In EAW-disinfected parts of the endoscopes, the culture-positive rates were 4.3% (2/47) in S-1 samples and 12.8% (6/47) in S-2 samples. In ethyl alcohol-disinfected area, the culture-positive rates were 2.1% (1/47) in S-3 samples and 25.5% (12/47) in S-4 samples. The colony counts of culture-positive samples ranged from 1 to 144. Pseudomonas aerugi-nasa was recovered from the angulation knob of an endoscope, but other contaminating organisms were mostly : normal flora or opportunistic pathogens. Conclusion : Although part of the endoscopes disinfected with 75% ethyl alcohol were contaminated with more organisms than EAW-disinfected areas, Cleantop WM-1□ showed a relatively good disinfection efficacy in reprocessing patient-used endoscopes. (Korean J Infect Dis 33:133∼138, 2001)

바터 팽대부에 생긴 유암종 1예

강명주,지삼룡,박석주,이재익,조영완,김준영,박성재,박은택,이연재,이상혁,설상영,배상균 인제대학교 2006 仁濟醫學 Vol.27 No.-

Carcinoid tumors have been reported in a wide range of organs but most commonly involve the lungs, bronchi and gastrointestinal tract. Within the gastrointestinal tract, appendix is the most common location for carcinoid, followed by the distal small intestine, the rectum, and the stomach. Among these, primary involvement of the ampulla of Vater is extremely rare. We report a case of carcinoid tumor of ampulla of Vater. A 62-year-old man presented with epigastric soreness. Gastroduodenal endoscopy showed hyperemic bulging mass on ampulla of Vater and diagnosed as carcinoid tumor by histologic finding, with immunohistochemical study. In ^(111)In-octreoscan, tumor had regional lymph node metastasis, but no evidence of distant metastasis. Pancreatoduodenectomy with lymph node dissection was performed.

Road-work과 Sauna가 體重減量 및 血漿 전해질 變化에 미치는 影響

全在完 서원대학교 응용과학연구소 1993 응용과학연구 Vol.2 No.1

The purpose of this study was to verity comparatively the difference of the physiological effect between road-work and sauna bath as a weight-loss method. The subjects of this study were 7 boxers in Seowon University. And to accomplish the purpose, the subjects were weighted and blood were sampled from them before and after 7km road-work(30') and 1 jour sauna-bath. The blood sample were analyzed in Chung-Buk Medical Center. The t-test of pre-post weight and plasma electrolytes in each method, and the ANOVA of pre-post difference in weight and plasma electrolytes between two method were done for the analysis of data. The results of this study were gained as following. 1. Weight decreased significantly in both methods, but the difference of weight-loss between two methods were not significantly appeared. 2. The Change of Na?? concentration in blood plasma was not significantly appeared after road-work but significantly appeared after sauna-bath. The difference of Na?? change between two methods was appeared significantly. 3. The Change of K?? concentration in blood plasma was not significantly appeared in both methods and the difference of K?? change between two methods was not also significant. 4. The Change of cl?? concentration in blood plasma was not significantly appeared in both methods and the difference of cl?? change between two methods was not also significant. Form above results, both road-work and sauna-bath were thought to be effective only for the temporary weigh loss. But statistically significant loss of Na?? after sauna indicated that road-work more effective and physiologically safe for the athletes' performance.

부인과적 진단 복강경술에 대한 임상적 고찰

곽재환,박진완,황태영,김현호,이원기 동아대학교의과대학 1992 동아의대학술지 Vol.4 No.1

Helicobacter pylori의 생육에 영향을 미치는 성분과 식품첨가물에 관한 연구

송재철,정혜진,박현정,조은경,신완철 한국식품영양학회 1999 韓國食品營養學會誌 Vol.12 No.5

본 연구에서는 일반적으로 섭취하고 있는 식품재료나 음식 중에 공통적으로 함유한 성분 또는 가공중에 많이 첨가되는 성분을 선정하여 이들이 Helicobacter pylori 생육에 어떤 영향을 미치는지를 검토하였다. 첫째, 일반식품의 주요 성분인 탄소원, 질소원, 무기질을 대상으로 Helicobacter pylori 생육에 미치는 영향을 검토하였다. 그 결과 식품성분 중 탄소원의 종류에 따라 균일 생육활성은 다르게 나타났다. 우선 단당류가 이당류나 다당류에 비교하여 생육을 촉진하였고 특히 단당류 중 포도당은 가장 균의 생육에 큰 영향을 미치는 것으로 나타났다. 그러나 만노오스는 균의 생육을 오히려 억제시키는 것으로 나타났다. 당알코올류인 솔비톨, 만니톨, 말티톨, 크리시톨 등은 균의 생육에 아무런 영향을 미치지 않은 것으로 나타났다. 질소원과 Helicobacter pylori의 생육과의 관계는 평소 식생활에서 많이 섭취된다고 생각되는 일반 음식에 많이 함유되어 있는 유기형 아미노산 성분고 무기형 질소화합물을 대상으로 균의 생육 정도를 비교하였다. 리신, 메티오닌, 시스테인, 트립토판 등은 균의 생육을 촉진하고 아르기닌, 황산암모늄, 염화암모늄 등은 균의 생육에 도움이 되지 않고 암노니아, 요소등은 균의 생육에 도움이 되지 않고 암모니아, 요소 등은 균의 생육에 조금 영향을 미침을 관찰할 수 있었다. 특히 리신과 메티오닌은 가장 균의 생육에 영향을 미치는 것으로 나타났다. 무기염류의 영향에서는 황산마그네슘, KH-2PO_4, 염화마그네슘 등은 큰 영향을 미치지 못하였고 황산철, 염화제일철, 염화제이철은 생육을 억제하는 것으로 나타났다. 식품첨가물의 Helicobacter pylori의 생육 정도를 검토한 것으로, 그 다음이 질화나트륨, 염화나트륨 순이었으며 토코페롤은 전혀 생육에 영향을 미치지 못하였다. The purpose of this study was to choose principal food components contained in diet foods and food additives used for manufacturing processed foods, and elucidate their in vivo effects on the growth pattern of Helicobacter pylori. To do this, the antibacterial effects of various sources of carbon, nitrogen and mineral as an effect agent on Helicobacter pylori were first assessed based upon bacterial growth degree. Results show that the source of carbon tested had different effects on bacterial growth of Helicobacter pylori. It was revealed that a promotional effect of monosaccharides resulted in enhanced growth of Helicobacter pylori compared with disaccharides and polysaccharides. In particular, glucose was observed to be most effective in growth of Helicobacter pylori among monosaccharides tested, whereas mannose to hinder the growth of Helicobacter pylori. Polyols such as sorbitol, mannitol, maltitol and xylitol was, however, observed to show no promotion or suppression effect on growth of Helicobacter pylori. Apart from these, the sources of amino acid and inorganic nitrogen were chosen and tested to assess the promotion or suppression effect of nitrogen sources on growth of Helicobacter pylori. It was found that amino acid such as lysine showed its promotion effect on the growth of Helicobacter pylori, while arginine, (NH_1)_2SO_4 and NH_4Cl showed no effect on its growth. Ammonia and urea were, however, observed to have a positive effect on the growth of Helicobacter pylori. Among these effect agents, lysine and methionine were revealed to show the most positive effect on growth of Helicobacter pylori. Minerals such as MgSO_4, KH_2PO_4, and MgCl_2 appeared to exert their positive growth effects, whereas CaCl_2, and CaSO_4 had a little effect. In addition FeSO_4, FeCl_2, and FeCl_3 brought suppression on the growth of Helicobacter Pylori. In studies of the growth of Helicobacter pylori by food additives, ascorbic acid showed extreme suppression on its growth. Sodium nitrate and sodium chloride were also found to be of negative effect on the growth of Helicobacter pylori in order of degree, whereas tocopherol had nothing to do with microbial growth.

아크릴로니트릴-4비닐피리딘 공중합체의 전기 전도성에 관한 연구

전재완,송해영,김동철,이래연 忠南大學校 産業技術硏究所 1987 산업기술연구논문집 Vol.2 No.2

Conducting Polymer was obtained by the modification of PAN4VP-Cu(Ⅱ) complex with iodine in acetone. The properties such as morphology, IR-spectrum, thermal degradation, catalytic activity, moisture regain, dye adsorption, tensile strength and favorable conditions for preparing the conducting polymer complex were investigated. Electrical conductivity was measured by changing the concentration of cupric salts and reation time. The experimental results are as follows: 1) The pH condition for the formation of PAN4VP complex was in the range from 10 to 11. 2) The morphology of PAN4VP-Cu(Ⅱ) complex and Cu S-PAN4VP was more compact than that of PAN4VP. 3) The catalytic activity of PAN4VP-Cu(Ⅱ) complex in dicomposition of hydrogen peroxide was affected by concentration of CuCl₂and reaction time, and was increased with their rises. 4) Maximum value of electrical condustivity of PAN4VP-Cu(Ⅱ) complex was 5.5×10Ω㎝ When modified with iodine in acetone, and that of CuxS-PAN4VP was 1.2×10Ω㎝ at the 40g/ℓ concentration of cupric sulfate. 5) Moisture regain of Cu S-PAN4VP was decreased by the introducing of Cu S, but dye adsorption was not decreased.

팔꿈치 경직 환자의 회복 운동을 위한 재활 로봇 시스템 개발

이정완,이재경 江原大學校 産業技術硏究所 2008 産業技術硏究 Vol.28 No.A

This paper describes the mechanical and control design of a robotic device for providing therapeutic assistance to arm movement following stroke. This is a new robot for arm therapy applicable to the training of activities of daily living in homes and clinics. This instrument has one degrees of freedom, and is equipped with position and force sensors. Repetitive movement can improve movement performance in patients with neurological or orthopaedic lesions. The application of robotics can serve to assist, enhance, evaluate, and document neurological and orthopaedic rehabilitation of movements. The new robot, the mechanical structure, the control circuit, the sensors and actuators and some safety aspects.