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표면 플라즈몬 공명 신호의 증폭을 위한 새로운 금 콜로이드 센서칩 제조와 특성 연구
임정혁,이경호,고광락,강신원,김재호 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1
New gold colloidal film sensor chips were employed to enhance the sensitivity of the Surface Plasmon Resonce (SPR). Au collodal solutions were synthesized, and Au colloidal films were fabricated by immobilization of colloid on vacuum deposited Au film through the coupling agent of 1,8-diaminooctane. Specific interaction of human IgG antibody to human antigen was monitored by in situ SPR measurement from both a smooth and a Au colloidal films. Au colloidal film sensor chips resulted in 27 % enhancements effect for the same reaction on SPR angle shifts compared to a smooth Au film.
A Non-binary C-R Hybrid DAC for 12 b 100 MS/s CMOS SAR ADCs with Fast Residue Settling
Jae-Geun Lim,Je-Min Jeon,Jun-Ho Boo,Yoon-Bin Im,Jae-Hyuk Lee,Sung-Han Do,Young-Jae Cho,Michael Choi,Gil-Cho Ahn,Seung-Hoon Lee 대한전자공학회 2021 Journal of semiconductor technology and science Vol.21 No.4
This work proposes two versions of a 12 b 100 MS/s successive-approximation register (SAR) ADC based on a non-binary C-R hybrid DAC. The proposed DAC applies a non-binary weighted capacitor array to the 7 MSBs to meet the settling requirement of the DAC output and determines the remaining 5 LSBs using the reference voltages generated from a simple resistor string to reduce the DAC area significantly. The Version 1 ADC in a 28 ㎚ CMOS adopts a synchronous SAR logic and a comparator with a tail capacitor and a reset switch to minimize power consumption. The Version 2 ADC in a 0.18 ㎛ CMOS employs an asynchronous SAR logic with simple meta-stability correction logic to achieve high-speed operation. The Version 1 ADC which has an active die area of 0.042 ㎟ shows a maximum signal-to-noise-and-distortion ratio (SNDR) and spurious-free dynamic range (SFDR) of 62.3 and 77.3 ㏈, respectively, consuming 1.3 ㎽ with a 1.0 V supply voltage. The Version 2 ADC is based on a similar analog circuit topology, showing a maximum SNDR and SFDR of 60.1 and 73.5 ㏈, respectively, with an active die area of 0.30 ㎟, operating at a 1.8 V supply voltage.
전자기식 충격흡수구조의 설계를 위한 동특성 해석 및 실험
이미선,배재성,황재혁,임재혁,Yi, Mi-Seon,Bae, Jae-Sung,Hwang, Jae-Hyuk,Im, Jae-Hyuk 항공우주시스템공학회 2012 항공우주시스템공학회지 Vol.6 No.1
A shock absorber with magnetic effects is suggested for a lunar space-ship expected to launch in 2025. The device consists of a copper steel combined tube, two magnets, and a piston. The piston is designed to move a magnet through the tube when it is pushed by an external impact. While the magnet is moving in the tube, it generates the eddy current force with the copper part of the tube and it also makes the large friction force with the steel part of the tube. Beside, it gets resistive forces against its movement such as the magnetic force with a steel-ring at the first time of the movement and the repulsive force with a same pole opposed magnet at the end time of the movement. In this thesis, results of analyses and experiments of each force are represented and the expected performance of the electromagnetic shock absorber is drawn from the results.
Effect of Liquid Fuels on the PAH and Soot Formation
Jae Hyuk Choi(최재혁),In Kyu Im(임인규),Byoung Chul Choi(최병철),Hwan-Ho KIM(김환호),Kyoung Woo Lee(이경우),Mann Eung Kim(김만응) 한국마린엔지니어링학회 2009 한국마린엔지니어링학회 학술대회 논문집 Vol.2009 No.-
In order to investigate the effect of benzene (C?H?) and toluene (C?H?) mixing on polycyclic aromatic hydrocarbon (PAH) and soot formation, benzene and toluene have been mixed in counterflow pure ethylene diffusion flame. Laser induced incandescence (LII) and laser induced fluorescence (LIF) techniques have been adopted to measure relative concentrations of soot volume fraction and polycyclic aromatic hydrocarbon (PAH) concentration, respectively. The experimental results showed that the mixing of liquid fuels in ethylene diffusion flame produces more PAHs and soot than that of pure ethylene diffusion flame. Especially, LII signal of 20% toluene flame increased about 3.5 times more than that of pure ethylene diffusion flame. It is considered that methyl (CH₃) radical generated by the initial pyrolysis of benzene can be contributed to the enhancement of PAH and soot formation, through the formation of propargyl (C₃H₃) radical.
Hyuk Joo Lee,Cheolkyung Sin,Hyeyeong Kim,Hyeon-Su Im,Jae-Cheol Jo,Yoo Jin Lee,Youjin Kim,Junseok Ahn,Soyoung Yoo,Su-Jin Koh,Seockhoon Chung 대한신경정신의학회 2023 PSYCHIATRY INVESTIGATION Vol.20 No.12
Objective The aim of the present study was to explore whether or not cancer patients’ viral anxiety and depression during the coronavirus-2019 (COVID-19) pandemic were associated with a fear of cancer progression. We also assessed whether coping strategies affected the relationship.Methods The present cross-sectional survey included cancer patients who visited Ulsan University Hospital in Ulsan, Korea. The participants’ demographic information and responses to the following symptoms rating scales were collected: Stress and Anxiety to Viral Epidemic–6; Patient Health Questionnaire–9; Cognitive Emotion Regulation Questionnaire-short version; or Fear of Progression Questionnaire-short version.Results Of the 558 cancer patients surveyed, 25 (4.5%) reported that their treatment schedule was delayed during the COVID-19 pandemic. The patients’ fear of progression was found to be related to age (β=-0.08; p=0.011), viral anxiety (β=0.40; p<0.001), depression (β=0.26; p<0.001), and catastrophizing coping strategies (β=0.15; p=0.004), for an overall adjusted R<sup>2</sup> of 0.46 (F=66.8; p<0.001). Mediation analysis showed that viral anxiety and depression were directly associated with fear of progression, while catastrophizing mediated this relationship.Conclusion Fear of progression in cancer patients was associated with viral anxiety, depression, and maladaptive coping techniques, such as catastrophizing, during the COVID-19 pandemic.
( Jae Hoon Moon ),( Min Kyung Hyun ),( Ja Youn Lee ),( Jung Im Shim ),( Tae Hyuk Kim ),( Hoon Sung Choi ),( Hwa Young Ahn ),( Kyung Won Kim ),( Do Joon Park ),( Young Joo Park ),( Ka Hee Yi ) 대한내과학회 2018 The Korean Journal of Internal Medicine Vol.33 No.4
Background/Aims: We evaluated the prevalence and characteristics of thyroid nodules detected by thyroid ultrasound (US) at health checkups and the associated clinical parameters. Methods: A total of 72,319 subjects who underwent thyroid US at three health checkup centers in Korea from January 2004 to December 2010 were included in this study. The correlations between the presence of thyroid nodules and other clinical parameters were analyzed. Results: The prevalence of thyroid nodules and cysts was 34.2% (n = 24,757). Thyroid nodules were more prevalent in women and older age groups. Among the subjects with thyroid nodules with size information (n = 24,686), 18,833 (76.3%) had nodules measuring ≤ 1.0 cm. Women and older age groups showed higher proportion of larger nodules. Percentage of women, age, body mass index (BMI), waist circumference, body fat composition, blood pressure, and the level of fasting glucose, total cholesterol, and low density lipoprotein cholesterol were higher in the subjects with thyroid nodules compared to those without nodules. The prevalence of metabolic syndrome and overt/subclinical thyrotoxic state was higher in the subjects with thyroid nodules. In the multivariable logistic regression analysis, women, age, BMI, metabolic syndrome, and thyrotoxicosis were independently associated with the presence of thyroid nodules. Conclusions: The high prevalence of thyroid nodules in people who underwent thyroid US at a health checkup suggests that increased detection of thyroid nodules resulted in an increased prevalence in the general population. However, metabolic disturbances may also have contributed to the increase in thyroid nodule prevalence in Korea.
Im, Ji Hyuk,Yang, Seung Jae,Yun, Chang Hun,Park, Chong Rae IOP Pub 2012 Nanotechnology Vol.23 No.3
<P>Carbon/TiO<SUB>2</SUB> composite nanotubes were fabricated via a very simple electrospinning process and their dual functionalities of adsorptivity and photocatalytic activity were evaluated using Rhodamine B (RhB) as a model organic pollutant. A poly(vinyl alcohol) (PVA) aqueous solution was directly electrospun into a coagulation bath containing titanium (IV) tetraisopropoxide (TTIP) solution so that PVA-core/TiO<SUB>2</SUB>-shell composite nanofibers were formed through the in situ sol–gel reaction of TTIP. The carbon/TiO<SUB>2</SUB> composite nanotubes were then fabricated by heat treatment of composite nanofibers under nitrogen atmosphere. By using several characterization methods, we confirmed that the resultant nanotubes consisted of anatase TiO<SUB>2</SUB> nanocrystallites embedded in a carbonaceous matrix. The prepared nanotubes exhibited fast adsorption of RhB with high capacity compared with a commercial porous carbon, and they also showed the photocatalytic decomposition activity for the dye molecules under UV irradiation comparable to the degradation by P-25 and ST-01 (commercial TiO<SUB>2</SUB>). Finally, the carbon/TiO<SUB>2</SUB> composite nanotubes exhibited several cycle performances of adsorption–photodegradation for RhB. This indicates that the composite nanotubes can adsorb and photodecompose organic pollutants repeatedly without additional activating processes.</P>
Second Korean guidelines for the management of Crohn`s disease
( Jae Jun Park ),( Suk-kyun Yang ),( Byong Duk Ye ),( Jong Wook Kim ),( Dong Il Park ),( Hyuk Yoon ),( Jong Pil Im ),( Kang Moon Lee ),( Sang Nam Yoon ),( Heeyoung Lee ) 대한장연구학회 2017 Intestinal Research Vol.15 No.1
Crohn`s disease (CD) is a chronic, progressive, and disabling inflammatory bowel disease (IBD) with an uncertain etiopathogenesis. CD can involve any site of the gastrointestinal tract from the mouth to the anus, and is associated with serious complications, such as bowel strictures, perforations, and fistula formation. The incidence and prevalence rates of CD in Korea are still lower compared with those in Western countries, but they have been rapidly increasing during the recent decades. Although there are no definitive curative modalities for CD, various medical and surgical therapies have been applied for the treatment of this disease. Concerning CD management, there have been substantial discrepancies among clinicians according to their personal experience and preference. To suggest recommendable approaches to the diverse problems of CD and to minimize the variations in treatment among physicians, guidelines for the management of CD were first published in 2012 by the IBD Study Group of the Korean Association for the Study of Intestinal Diseases. These are the revised guidelines based on updated evidence, accumulated since 2012. These guidelines were developed by using mainly adaptation methods, and encompass induction and maintenance treatment of CD, treatment based on disease location, treatment of CD complications, including stricture and fistula, surgical treatment, and prevention of postoperative recurrence. These are the second Korean guidelines for the management of CD and will be continuously revised as new evidence is collected. (Intest Res 2017;15:38-67)
Genome-wide linkage analysis for ocular and nasal anthropometric traits in a Mongolian population
Im, Sun-Wha,Kim, Hyun-Jin,Lee, Mi-Kyeong,Yi, Jae-Hyuk,Jargal, Ganchimeg,Sung, Joo-Hon,Cho, Sung-Il,Kim, Jong-Il Korean Society for Biochemistry and Molecular Bion 2010 Experimental and molecular medicine Vol.42 No.12
Anthropometric traits for eyes and nose are complex quantitative traits influenced by genetic and environmental factors. To date, there have been few reports on the contribution of genetic influence to these traits in Asian populations. The aim of this study was to determine the genetic effect and quantitative trait locus (QTL) of seven traits eyes- and nose-related anthropometric measurements in an isolated Mongolian population. Frontal and lateral photographs were obtained from 1,014 individuals (434 males and 580 females) of Mongolian origin. A total of 349 short tandem repeat markers on 22 autosomes were genotyped for each individual. Heritability estimates of the seven ocular and nasal traits, adjusted for significant covariates, ranged from 0.48 to 0.90, providing evidence for a genetic influence. Variance-component linkage analyses revealed 10 suggestive linkage signals on 5q34 (LOD = 3.2), 18q12.2 (LOD = 2.7), 5q15 (LOD = 2.0), 9q34.2 (LOD = 1.9), 5q34 (LOD = 1.9), 17q22 (LOD = 1.9), 13q33.3 (LOD = 2.7), 1q36.22 (LOD = 1.9), 4q32.1 (LOD = 2.1) and 15q22.31 (LOD = 2.9). Our study provides the first evidence that genetics influences nasal and ocular traits in a Mongolian population. Additional collaborative efforts will further extend our understanding of the link between genetic factors and human anthropometric traits.