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An Experimental Study on Interrelation of Influential Parameters on Unbonded Tendon Stress
Moon, Jeong-Ho,Lim, Jae-Hyung Korea Concrete Institute 2006 International Journal of Concrete Structures and M Vol.18 No.e2
The purpose of this study is to investigate the relations between unbonded tendon stress and its influential parameters, i.e. bonded reinforcement ratio, span/depth ratio, and loading type. To this end, the influence of such parameters was examined with twenty eight test results of previous studies. Afterwards, an experimental study was carried out with twenty one test specimens. The investigation of previous and current experiments revealed the followings; (1) The bonded reinforcement ratio and prestressing ratio were proved to be important variables on the unbonded tendon stress. (2) The ratio of span to depth and the type of loading affected the unbonded tendon stress partially although their effects varied with bonded reinforcement ratio. (3) AASHTO LRFD Code and Moon/Lim's design equations predicted the experimental results well with the safety margin.
Moon, Jeong-Ho,Shin, Kyung-Jae,Lim, Jae-Hyung,Lee, Sun-Hwa Korea Concrete Institute 2000 KCI concrete journal Vol.12 No.1
The research purpose of this paper is to investigate the influential Parameters on the unbonded tendon stress. The parameters were the reinforcing ratio, the prestressing ratio, and the loading type. To this end. first, the influence of parameters were examined with twenty eight test results obtained from references. Then, an experimental study was carried out with nine specimens. Test variables were the reinforcing ratio and the prestressing ratio. Specimens were divided equally into three groups and each group had a different level of the reinforcing ratio. Each specimen within a group has a different level of the prestressing ratio. The investigation with previous and current tests revealed the followings; (1) the length of crack distribution zone does not have a close relation with the length of plastic hinge. (2) the prestressing ratio does not affect both the length of crack distribution and the length of plastic hinge, (3) the tendon stress variation is in reverse relation with the ratios of mild steels and tendons, (4) the loading type nay not affect significantly the length of crack distribution zone, (5) AASHTO LRFD Code equation and Moon/Lim's design equation predicted the test results well with some safety margins.
서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)
김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1
In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.
Lee, Moon Hee,Han, Min Ho,Lee, Dae-Sung,Park, Cheol,Hong, Su-Hyun,Kim, Gi-Young,Hong, Sang Hoon,Song, Kyoung Seob,Choi, Il-Whan,Cha, Hee-Jae,Choi, Yung Hyun UNKNOWN 2017 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol.39 No.2
<P>In the present study, we investigated the cytoprotective efficacy of morin, a natural flavonoid, against oxidative stress and elucidated the underlying mechanisms in C2C12 myoblasts. Our results indicated that morin treatment prior to hydrogen peroxide (H2O2) exposure significantly increased cell viability and prevented the generation of reactive oxygen species. H2O2-induced comet-like DNA formation and gamma H2AX phosphorylation were also markedly suppressed by morin with a parallel inhibition of apoptosis in C2C12 myoblasts, suggesting that morin prevented H2O2-induced cellular DNA damage. Furthermore, morin markedly enhanced the expression of heme oxygenase-1 (HO-1) associated with the induction and phosphorylation of nuclear factor-erythroid 2-related factor 2 (Nrf2) and the inhibition of Kelch-like ECH-associated protein 1 (Keapl) expression. Notably, these events were eliminated by transient transfection with Nrf2-specific small interfering RNA. Additional experiments demonstrated that the activation of the Nrf2/HO-1 pathway by morin was mediated by the extracellular signal-regulated kinase (ERK) signaling cascade. This phenomenon was confirmed with suppressed Nrf2 phosphorylation and consequently diminished HO-1 expression in cells treated with a pharmacological inhibitor of ERK. Collectively, these results demonstrated that morin augments the cellular antioxidant defense capacity through the activation of Nrf2/HO-1 signaling, which involves the activation of the ERK pathway, thereby protecting C2C12 myoblasts from H2O2,-induced oxidative cytotoxicity.</P>
Lee, Moon Hee,Cha, Hee-Jae,Choi, Eun Ok,Han, Min Ho,Kim, Sung Ok,Kim, Gi-Young,Hong, Su Hyun,Park, Cheol,Moon, Sung-Kwon,Jeong, Soon-Jeong,Jeong, Moon-Jin,Kim, Wun-Jae,Choi, Yung Hyun Spandidos Publications 2017 International journal of molecular medicine Vol.39 No.3
<P>Natural phytochemicals of plant origin, including flavonoids, have been found to be potent antioxidants providing beneficial effects against oxidative stress-related diseases. The present study was carried out to investigate the antioxidant properties of morin, a flavonoid originally isolated from the flowering plants of the Moraceae family. Superoxide dismutase (SOD)-like activity and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS(center dot+)) radical scavenging activity were determined. We also investigated the cytoprotective effects of morin against hydrogen peroxide (H2O2)-induced DNA damage and apoptosis in V79-4 Chinese hamster lung fibroblasts. Our results demonstrated that morin had strong scavenging effects against ABTS' radicals with enhanced SOD activity, which varied in a dose-dependent manner. Morin was found to reduce H2O2-induced intracellular reactive oxygen species generation and nuclear DNA damage, and it recovered cell viability damaged by H2O2 via inhibition of mitochondrial dysfunction-mediated apoptosis. Notably, the treatment of V79-4 cells with morin markedly enhanced the expression of heme oxygenase-1 (HO-1) but not quinone oxidoreductase-1, which was associated with the increased expression and phosphorylation of nuclear factor-erythroid 2-related factor 2 (Nrf2) and the downregulation of Kelch-like ECH-associated protein 1 expression. Based on our findings, we conclude that morin effectively ameliorated oxidative stress-induced DNA damage through intrinsic free radical scavenging activity and activation of the Nrf2/HO-1 pathway.</P>
디자인에서의 조형법칙 적용 사례연구 : 인쇄광고물을 중심으로
문재호 경희대학교 디자인연구원 2000 예술· 디자인학연구 Vol.3 No.1
A humans sight is basically organized to recognize the awareness of the continuous and multifarious dots and lines. These gestalt psychology and gestalt visuality are formed by gestalt regulation. Gestalt regulation is within the limit of art-studies gestalt and is called "the rules and methods of gestalt". This several gestalt regulation defines the inner beauty with the gestalt relation