Inhibitory effects of seaweed extracts on α-glucosidase and α-amylase activities, and the metabolic regulation on glycolysis in HepG2 cells

Hyunju Shin,Eunji Kim,Missok Kim,Jeongmin Lee,Yoonhwa Jeong 한국식품영양과학회 2011 한국식품영양과학회 학술대회발표집 Vol.2011 No.10

Tablorer – An Interactive Tree Visualization System for Tablet PCs

Shin, HyunJu,Park, GwangHyun,Han, JungHyun Blackwell Publishing Ltd 2011 Computer graphics forum Vol.30 No.3

<P><B>Abstract</B></P><P>A variety of mobile devices are available today, but there is no dominant tree visualization system in the devices. This paper proposes Tablorer, a novel interactive tree visualization system for medium‐sized mobile devices, especially for tablet PCs. The system shows the hierarchical information with a compact way using an expandable table format. For efficient navigation, the system provides an integrated view of context and focus information. The experimental results show that Tablorer can reduce the search time by about 22%.</P>

Salvage proton beam therapy for locoregional recurrence of non-small cell lung cancer

Hyunju Shin,Jae Myoung Noh,Hongryull Pyo,Yong Chan Ahn,Dongryul Oh 대한방사선종양학회 2021 Radiation Oncology Journal Vol.39 No.1

Purpose: This study aimed to evaluate the clinical outcomes and toxicities of salvage proton beam therapy (PBT) in patients with locoregional recurrent non-small cell lung cancer (NSCLC). Materials and Methods: We retrospectively reviewed 53 patients who received salvage PBT for locoregionally recurrent NSCLC between January 2016 and December 2019. The median clinical target volume (CTV) was 71.2 cm3 (range, 13.3 to 1,200.7 cm3). The median prescribed dose was 64.0 cobalt gray equivalent (CGE) (range, 45.0 to 70.0 CGE). One-third of the patients (32.1%) received concurrent chemoradiotherapy (CCRT). Results: The patients’ median age was 67 years (range, 44 to 86 years). The initial treatments were surgery in 31 (58.5%), definitive CCRT in 12 (22.6%), and definitive radiotherapy in 10 (18.9%) patients. The median disease-free interval (DFI) was 14 months (range, 3 to 112 months). Thirty-seven patients (69.8%) had a previous radiotherapy history. Among them, 18 patients (48.7%) had in-field recurrence. The median follow-up time after salvage PBT was 15.0 months (range, 3.5 to 49.3 months). During the follow-up period, 26 patients (49.1%) experienced disease progression: local in 13 (24.5%), regional in 14 (26.5%), and distant metastases in 15 (26.5%). The 2-year overall survival (OS) rate, local control rate, and progression-free survival rate were 79.2%, 68.2%, and 37.1%, respectively. Shorter DFI (≤12 months; p = 0.015) and larger CTV (>80 mL; p = 0.014) were associated with poor OS. Grade 3 toxicities occurred in 8 patients (15.1%): esophagitis in 2, dermatitis in 3, and pulmonary toxicities in 4. Conclusion: Salvage PBT for locoregionally recurrent NSCLC was effective, and treatment-related toxicities were tolerable.

Inhibitory effect of seaweed ethanol extracts on glucose uptake in human Caco-2 cells

Hyunju Shin,Eunji Kim,Missok Kim,Jeongmin Lee,Yoonhwa Jeong 한국식품영양과학회 2011 한국식품영양과학회 학술대회발표집 Vol.2011 No.10

THE INFLUENCE OF HUMOR APPEAL IN LUXURY ADVERTISING

Hyunju Shin,Sukki Yoon,Kacy Kim 글로벌지식마케팅경영학회 2020 Global Marketing Conference Vol.2020 No.11

Development of an Isotope-Dilution Liquid Chromatography/Mass Spectrometric Method for the Accurate Determination of Acetaminophen in Tablets

Hyunju Shin,김병주,Joonhee Lee,Euijin Hwang 대한화학회 2010 Bulletin of the Korean Chemical Society Vol.31 No.12

Acetaminophen (N-acetyl-p-aminophenol) is one of the most popular analgesic and antipyretic drugs. An isotope dilution mass spectrometric method based on LC/MS was developed as a candidate reference method for the accurate determination of acetaminophen in pharmaceutical product. After spiking an isotope labeled acetaminophen (acetyl-13C2, 15Nacetaminophen)as an internal standard, tablet extracts were analyzed by LC/MS in a selected reaction monitoring (SRM) mode to detect ions at m/z 152→110 and m/z 155→111 for acetaminophen and acetyl-13C2, 15N-acetaminophen, respectively.The repeatability and reproducibility of the developed ID/LC-MS method were tested for the validation and assessment of metrological quality of the method.

Factors Affecting Air Cargo Demand: Focus on Trade Volumes between South Korea and Intra-Asia

신현주(Hyunju Shin),이건우(Gunwoo Lee) 한국국제상학회 2019 國際商學 Vol.34 No.3

우리나라 항공화물의 수출입 비중은 물동량 기준으로 0.3%로 낮은 수치를 나타내고 있지만, 운송 화물가액 관점에서 2017년 기준 항공화물 수출액은 1,750억 달러로 총 수출액의 30.5%를 차지하고 있다. 최근 항공화물 운송 부문은 IT 제품 및 특수화물의 수요 확대 등으로 수출 증가세를 전망하였지만 무역 갈등과 세계 무역량 약화 등으로 인해 운송 실적이 하향세를 보이고 있다. 이처럼 다양한 요인들로 인하여 항공화물수요가 민감하게 반응하는 것을 알 수있다. 본 연구에서는 인트라아시아 국가를 대상으로 서울(인천국제공항, 김포국제공항)을 기종점으로하여 요인들의 영향력을 확인할 수 있는 항공화물 수입/수출 모형을 제시하였다. 모형 도출결과 항공화물수요에 양의 상관관계를 나타내는 요인으로 1인당 GDP, 총수출, 한한령, FTA 체결, 첨단기술제품 수출을 확인하였고 음의 상관관계를 나타내는 요인으로 인플레이션, 실업률,전염병, 금융위기를 확인하였다. 모형을 기반으로 국가별 영향 요인에 따라 항공화물수요 변화량 예측 및 이를 통한 사전대비와 전략 마련에 도움이 될 것으로 기대된다. Purpose : The purpose of this study is to identify the factors that affect air cargo demand between South Korea and Intra-Asia. Research design, data, methodology : The OFOD data provided by ICAO was used as a dependent variable and factors were used as independent variables. The research method is an analysis using ARIMAX/SARIMAX model. Results : As a result this research, we found that air cargo demand has positive correlations with GDP per capita, Gross exports, A law that bans Korean culture in China, FTA, and High-tech product exports. On the other hand, we found that air cargo demand has negative correlations with Inflation, Unemployment rate, Epidemic, Financial crisis. Conclusions : This study when it expected that changes or occur of factor, we anticipate changes the air cargo demand, which will help country or airline prepare ahead and strategies.

뉴 미디어 시대 패션소비자의 정보 탐색과 공유

신현주 ( Hyunju Shin ),이규혜 ( Kyu-hye Lee ) 복식문화학회 2018 服飾文化硏究 Vol.26 No.2

As mobile shopping has increased in the new media age, fashion consumers’ decision making and product consumption processes have changed. The volume of consumerdriven information has expanded since media and social networking sites have enabled consumers to share information they obtain. The purpose of this study was to determine the factors affecting information searching strategies and information sharing about fashion products. An online survey collected data from 466 respondents, relating to the influence of product price level and consumer SNS commitment level on information search and information sharing. Experimental design of three product price level and two consumer SNS commitment level was used. Analysis of the data identified factors in fashion information searching as ongoing searching, prepurchase web portal information search, and prepurchase marketing information search. For low-price fashion products, prepurchase product-detail influenced intention to share information. For mid-priced products, ongoing search significantly affected intention to share information. Both ongoing search and prepurchase marketing information search showed significant effects for high-price products. Consumers who are more committed to SNS engaged in significantly more searching in all aspects of information search factors. Significant interaction effect was detected for consumer SNS commitment level and product price level. When consumers with low consumer SNS commitment search for information on lower-priced fashion products, they are less likely do a prepurchase web portal information search.

Decision Tree 분류기를 사용한 심전도 데이터 정확도 향상에 관한 연구

이현주(HyunJu Lee),신동일(Dongll Shin),신동규(Dongkyoo Shin) 한국정보과학회 2012 한국정보과학회 학술발표논문집 Vol.39 No.1B

심전도 질환 데이터는 일반적으로 분류기를 사용한 실험이 많다. 심전도 신호는 QRS-Complex와 R-R interval을 추출하는 경우가 많은데 본 실험에서는 R-R interval을 추출하여 실험하였다. 심전도 데이터의 분류 실험은 일반적으로 SVM(Support Vector Machine)과 MLP(Multilayer Perceptron)으로 실험되지만 본 실험은 Decision Tree를 사용하여 정확도 향상을 추구하였다. 그리고 정확도 비교 분석을 위해 SVM과 MLP 분류기 실험을 같이 수행하였고, 동일한 데이터와 간격으로 실험한 타 논문의 결과와 비교해 보았다. Decision Tree를 다른 분류기와 타 논문의 결과와 비교해 보니 정확도 부분에서는 Decision Tree가 가장 우수하였다.

Low serum 25-hydroxyvitamin D levels, tooth loss, and the prevalence of severe periodontitis in Koreans aged 50 years and older

Kim, Hyunju,Shin, Min-Ho,Yoon, Suk-Ja,Kweon, Sun-Seog,Lee, Young-Hoon,Choi, Chang-Kyun,Kim, OkJoon,Kim, Young-Joon,Chung, HyunJu,Kim, Ok-Su Korean Academy of Periodontology 2020 Journal of Periodontal & Implant Science Vol.50 No.6

Purpose: Vitamin D deficiency may cause bone loss and increased inflammation, which are well-known symptoms of periodontal disease. This study investigated whether serum 25-hydroxyvitamin D (25(OH)D) levels are associated with periodontal disease status and tooth loss. Methods: Cross-sectional data from 5,405 individuals aged ≥50 years (2,253 males and 3,152 females) were obtained from the 2008-2010 Dong-gu study, a prospective cohort study of risk factors for chronic diseases. Periodontal examinations were conducted to evaluate the number of remaining teeth, the periodontal probing depth (PPD), the clinical attachment level (CAL), and bleeding on probing. The percentages of sites with PPD ≥4 mm and CAL ≥4 mm were recorded for each participant. The severity of periodontitis was classified using the Centers for Disease Control and Prevention and the American Academy of Periodontology case definitions. Serum 25(OH)D levels were classified as reflecting severe deficiency, deficiency, insufficiency, or sufficiency. Multivariate linear regression analysis was performed to assess the associations of serum 25(OH)D levels with periodontal parameters and the number of remaining teeth after adjusting for confounders including age, smoking status, alcohol consumption status, month of blood collection, and physical activity. Multivariate logistic regression was used to evaluate the association between serum vitamin D levels and severe periodontitis. An overall statistical analysis and a stratified analysis by sex were performed. Results: Overall, the rates of severe deficiency, deficiency, insufficiency, and sufficiency were 6.5%, 67.9%, 22.4%, and 3.2%, respectively. After adjustment for confounders, vitamin D levels were directly associated with the number of remaining teeth, an association that was significant in males, but not in females. Sufficient serum 25(OH)D was associated with a low frequency of severe periodontitis. Conclusions: This population-based cross-sectional study indicates that low serum 25(OH) D is significantly associated with tooth loss and severe periodontitis in Koreans aged 50 years and older.