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      • 원위 대퇴골의 고립성 골연골종에서 발생한 속발성 연골 육종 1례 보고

        정필현,황장수,강석,김용민,오형호,채동주,김종필 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

        연골육종은 비교적 서서히 자라며 늦게 전이하는 악성 연골 종양으로 알려져 있다. 골 연골종에서 발생한 속발성 연골육종은 발생빈도는 드물며 타부위로의 전이가 적고 악성도가 낮은 경우가 많아 적합한 수술적 치료로서 좋은 예후를 보이는 것으로 보고되고 있다. 본 동국대학교 정형외과학 교실에서는 우측 대퇴골 원위부 골간단부에 생긴 고립성 골 연골종에서 이차적으로 발생한 연골육종을 치험한 바 문헌고찰과 함께 보고하는 바이다. A case of Secondary Chondrosarcoma Arising from Solitary Osteochondroma of the Distal Femur Department of Orthopaedic Surgery, College of Medicine, DongGuk University Phil Hyun Chung M.D., Jung Su Hwang M.D., Suk Kang M.D., Yang Mln Kim M.D., Hyung Ho Oh M.D., Dong Ju Chae M.D., Jong Pil Kim M.D. Chondrpsarcoma is a malignant cartilage-forming tumor that grows slowly and metastasis of this tumor occurs in late stage. Secondary chondrosarcomas arising from a solitary osteocartilaginous exostosis are rare and those have a better prognosis than other chondrosarcomas, and they rarely metastasize. We present our experience with a case of secondary chondrpsarcoma arising in solitary osteochondroma of distal metaphysis of right femur with clinical details.

      • SCOPUSKCI등재
      • KCI등재

        상악 정중부에 역위 매복된 과잉치의 악골 내 이동

        이석우,이제호,김성오,최형준,손홍규,최병재 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.4

        과잉치는 상악 정중부에서 주로 발견되며,과잉치의 발생 기전은 유전적 또는 환경적 원인에 의하여 치배 형성기 동안에 정상 치판의 비정상적 증식에 의한 것으로 보고되었다. 과잉치로 인한 합병증으로는 인접 영구치의 맹출 장애와 전위,회전,정중이개,비강으로의 맹출,낭종 형성 등 이 있다. 과잉치를 외과적으로 발거하기 위한 시기에 대해서는 논란이 되고 있다. 인접치의 배열과 맹출 장애,전위를 야기할 수 있기 때문에 조기에 발거하자는 견해와 어린이의 행동 조절 및 인접 영구치의 치근 형성 정도를 고려하여 8~l0세 이후에 발거 하자는 견해가 있다. 후자와 같이 외과적 발거 시기를 연기할 경우,역위 및 수평 매복된 과잉치는 악골 내에서 비강 또는 경구개,소구치 부위 등으로 이동할 수 있으며,과잉치의 이동과 전상악골의 수직고경 증가로 인하여 외과적 발거 시 난이도가 높아질 수 있다. 따라서,역위 및 수평 매복된 과잉치의 외과적 발거 시기를 결정하기 위하여 연기하는 경우에 과잉치의 악골 내 이동을고려해야한다. 이 증례는 상악 정중부에 역위 매복된 과잉치가 있어서 내원한 6~7세의 어린이에서 과잉치의 외과적 발거 시기를 결정하기 위하여 주기적인 방사선 학적 검사로 관찰하던 중에 2~3년 후 과잉치 위치가 악골 내에서 초진 시 위치로부터 이동된 경우로 이를 보고하는 바이다. Supernumerary teeth are frequently found in the anterior portion of the maxilla and develop as a result of abnormal proliferation of the dental lamina during tooth germ formation, caused by genetic or environmental factors. They may result in various complications, such as eruption interference, displacement, rotation of adjacent teeth, diastema, eruption into the nasal cavity, and development of dentigerous cyst. The optimal time for surgical extraction of supernumerary teeth has been a controversial issue. Someone prefer early surgical extraction because supernumerary teeth can cause eruption interference and displacement of adjacent teeth, eventually altering occlusion. Others prefer to delay surgical extraction until 8~10 years of age in consideration of root maturation of the adjacent teeth and also patient's behavior. When surgical extraction of supernumerary teeth is postponed, there is possibility that impacted supernumerary teeth in the inverted or horizontal position move toward the nasal cavity, hard palate, or premolar area. When such intraosseous tooth migration is combined with the vertical growth of the maxilla. surgical approach becomes even harder. Therefore, possibility of intraosseous tooth migration should be considered as an important factor when deciding appropriate time for surgical extraction. We are presenting cases of mesiodens which showed intraosseous migration during 2~3 years of follow-up period since the first diagnosis had been made at the 6~7 years of age.

      • 직업선택 요인에 대한 여자대학생의 인식에 대한 연구

        吉亨奭,吳眞美 덕성여자대학교 학생생활연구소 1989 學生生活硏究 Vol.9 No.-

        A primary objective of this research is to explore the co­eds` attitude toward their own career. For the purpose, two separated materials were analysed : the student`s self­consciousness on job and societies response to women employees. The result demonstrates two paradoxical phenomena : First, though students have fully motivated active and progressive attitude on their own career, they gravely lack information on occupations in general and are not prepared systematically to participate in social life. Second, the established social institutions have enough preparation to accept women in their own institutions re­forming the internal regulations of business firms and changing their own consciousness according to the rapid social change, still the practice is limitted by traditional behavior patterns and conservative latent value system, For a college and higher educational institutions, these double paradoxes operate as the most fundamental difficulties to im­prove the co­eds` career education program. In spite of the paradoxical situation, the situation itself should be a turning point for the more relevant career program which school has to set for the co­eds`. To concretize problems, the following findings must be accepted carefully. 1) There is gap between the motivation of the co­eds to have occupation on society and the practical behavior of them in social institutions. In other words, even of women`s aspi­ration and progressive desire to have a job as a career is highly motivated, still their practical understanding of occupation and preparation are far below than the motivation. Therefore, it is one of the urgent task to cultivate their consciousness more realistically. 2) Sexism in society is unneglectable phenomena. But a revolt against it is not enough. The reality, theory, and conscious­ness of sexism must be analysedm reformed, and innovated through a critical approach in cultural and social context. However, school does not support the anti―sexism by means of systematized knowledge about women`s culture and future ori­entation of society. For the task, therefore, a special curriculum must be organized. 3) One of the most serious problems for the co­eds who plan their own social career is the double­triple role of a woman related to self, home, and occupation. If there in no con­ceptual change of occupation, it would be impossible to adjust modern trends of societal life. Therefore school must suggest a new concept of occupation as well as family life. 4) In general the career guidance system of school is inappro­priate. School does not have well­organized institutions for a career developing program. More extended and effec­tive reshaping of the system is critically needed. Based on above problems, this research could suggest mote practi­cal and concrete alternatives for the co­eds` career education. 1) Current curriculum should be re­organized according to more advanced ideal for a career education. For instance ; even though without direct relationship with specific academic field, the ideal and reality of occupation, marriage and job, the role of woman in future society, the structural change of society, and a self­realization of womanhood etc should be prepared as general education for the co­eds. 2) The career guidance institution of school should be expand­ed and re­organized in terms of co­operation with social firms, and institutions. For the career education, more serious and pratical academic research has to be done by the guidance institution. Information supply for the job―seeker is not enough. Research function of the guidance center should be enforced to instruct practical need and preparation in skill of co­eds as well as motivating their attitude. 3) Finally, it should be emphasized that the attitude and understanding of occupation of professors have to be shifted from conservative stereo­typed one to more opened and pro­gressive view on it. It is strange to say that a lot of professors, in spite of their creative contributions is academic field, remain in cultural lag in situational change of society. For a sound, desirable planning for a career education, the campus culture itself should be changed in line with societal reform. As a conclusion, three facts are demonstrated. 1) The co­eds are fully motivated for their own career. 2) However, the motivation is still on the level of ideal. Practical preparation is hardly realistic. 3) Current guidance system, including curriculum has to be critically revised.

      • 맥반석의 물리화학적 특성 : 수안보 맥반석을 중심으로

        한오형,정대석 조선대학교 동력자원연구소 1997 動力資源硏究所誌 Vol.19 No.1

        The factory wastes, polluted air and water by a industrial development have been contaminated our living environment in the change processing to join the ranks of advenced countries. In order to improve this environment using the Makban-stone which known to be useful in human body, the experiment of mineralogical property survey and heavy metal adsorption is done. Summarized results are as follows : 1. The major minerals of the Makban-stone through microscopic survey and X-ray diffraction analysis are quartz, plagioclase, microcline, amphibole, and biotite : minor minerals are chlorite, epidote, sericite, montmorillonite, and opaque minerals. 2. The Makban-stone is similar to the samples from Japan, according to chemical component survey, and compared with domestic granite, it shows that the content of SiO₂ is low, and the content of Al₂O₃ high. 3. According to the SEM analysis, most of feldspars have so many pores ranging 1∼10μ, and the shape of pores is a cylindrical one ranging 7∼14A˚. The result of an opening volume measurement by particle analysis is shown that the pores have very good structures needed to be adsorpted. 4. Regardless of pH value, it is confirmed that the Makban-stone absorbed heavy metals(Cd^2+, Zn^2+, Pb^2+, Cu^2+, and Cr^6+). 5. The adsorption of heavy metals by the Makban-stone quoted the Freundlich's isotherm equation. A inclination of Pb, Zn, and Cd, by the least-square methods is 0.2, 0.068, and 0.37, but Cr and Cu with inclination more than 2 cannot use for absorbent.

      • 최근 10년간 원광의대병원에서 시행한 소아 심장혈관 수술의 임상적 고찰

        윤향석,정수미,최두영,오광수,오연균,김종덕,양현웅,이삼윤,김형곤,최종범,최순호,노병석 圓光大學校 醫科學硏究所 1995 圓光醫科學 Vol.11 No.2

        We reviewed 10 years experiences of the clinical aspects and early postoperative results in 544 pediatric patients(age less than 16 years old). Among them. 529 cases had the congenital heart diseases, and 15 had the acquired diseases. Open heart surgery was performed in 413 patients. 115 cases were treated with non-open heart surgery. 16 with interventional catheterization. Annual increase of the cardiac patients was not significant in recent 10 years, except slight increase in 1994. The mean age of the study patients had been evidently changed to younger year by year. Total mortality rate of the open heart surgery was 6.4%. The cyanotic congenital heart diseases were high in early postoperative mortality by 25.7%, whereas 4% in acyanotic group. The age group less than one month was most highest in surgical mortality(66.7%). There were no deaths in patients with patent ductus arteriosus(103 cases), atrial septal defect(83 cases) or pulmonary stenosis(17 cases). Among 220 patients with ventricular septal defects(VSD). 10(4.5%) were died early postoperatively. In cyanotic group, the patients with pulmonary atresia with ventricular septal defects(PAVSD), transposition of the great arteries(TGA), interrupted aortic arch(IAA), complex cardiac anomalies with isomerism seemed to be most susceptible to an early death.

      • 1990學年度 德成女子大學校 新入生의 特性에 對한 調査硏究

        吉亨奭,吳眞美 덕성여자대학교 학생생활연구소 1991 學生生活硏究 Vol.10 No.-

        This research is to demonstrate various characteristics of freshmen in 1990. The ways, which are approached to the task, are conformed two surveys, the are is questionnaire the other is MMPI. Sample size is 1090 (84.5%) and 1064 (82.4%) correspondingly. The items of questionnaire are as following ; 1.Personal identification (age, residential area, religion, physical condition, blood type etc). 2.Family (parents, vocation, educational background, family size, ethos of home etc). 3.Economic condition (income, living standard, etc). 4.School adjustment (motive and practical procedure selecting school and department Conflict and Stability in present situation, expectation toward school administration and professor). 5.Campus life, (difficulties and problems in campus, extra curricular activities, fellowshig etc.) 6.Value orientation and future plan (personal value system, life style, social consciousness, world-view, career program etc.) Compare to previous year's survey, there is no significant difference. However, several findings are to be considered seriously. 1.Family size in becoming more smaller. 2.Economic condition is improring. 3.Value orientation is rather individualistic than communal, and pragmatic. 4.Comparatively, Subjective factor in selection of school and deciding of major field is increasing. 5.Career-plan is more connectely involved in campus-life.

      • 유한세프라딘 캅셀(세프라딘 500 mg)에 대한 브로드세프 캅셀의 생물학적 동등성

        조혜영,이석,강현아,오인준,임동구,문재동,이용복 전남대학교 약품개발연구소 2002 약품개발연구지 Vol.11 No.-

        Cepharadine is a first generation cephalosporin and has broad spectrum antibacterial activity against gram-positive and gram-negative microorganisms, through inhibition of bacterial cell wall synthesis. Cephradine is useful for treatment of infections of the urinary and respiratory tract, skin and soft tissues. The purpose of the present study was to evaluate the bioequinalence of two cepharadine capsules, Cefradine Yuhan (Yuhan Corporation) and Broadcef (Ilsung Pharmaceuticals Co. Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). The cephradine release from the two cephradine capsules ?? was tested using KP Ⅶ Apparatus Ⅱ method with various different kinds of dissolution media (pH 1.2, 4.0, 6.8 buffer solution and water). Twenty normal male volunteers, 23.10±2.90 years in age and 67.69±8.04 ㎏ in body weight, were divided into two groups and a randomized 2×2 cross-over study was employed. After one capsule containing 500 ㎎ as cephradine was orally administered, blood was taken at predetermined time intervals and the concentrations of cepharadine in serum were determined using HPLC method with UV detector. The dissolution profiles of two cephradine capsules were very similar at all dissolution media. Besides, the phaemacokinetic parameters such as AUC_t, C_max and T_max were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC_t and C_max and untransformed T_max. The results showed that the differences in AUC_t, C_max and T_max between two capsules based on the Cefradine Yuhan were -2.87%, -0.96% and -4.85%, respectively. There were no sequence effects between two capsules in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.25) (e.g., log(0.93)∼log(1.02) and log(0.88)∼log(1.13) for AUC_t, and C_max, respectively). the 90% confidence interval using untransformed data was within ±20% (e.g., -17.54∼7.78 for T_max). All parameters met the criteria of KFDA guideline for bioequivalence, indicating that Broadcef capsule is bioequivalent to Cefradine Yuhan capsule.

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