비부착 긴장재의 응력산정을 위한 극한강도 설계식의 평가

임재형(Lim, Jae-Hyung),문정호(Moon, Jeong-Ho),이리형(Lee, Li-Hyung) 한국콘크리트학회 1999 콘크리트학회논문집 Vol.11 No.3

Bucillamine prevents cisplatin-induced ototoxicity through induction of glutathione and antioxidant genes

Kim, Se-Jin,Ho Hur, Joon,Park, Channy,Kim, Hyung-Jin,Oh, Gi-Su,Lee, Joon No,Yoo, Su-Jin,Choe, Seong-Kyu,So, Hong-Seob,Lim, David J,Moon, Sung K,Park, Raekil Nature Publishing Group 2015 Experimental and molecular medicine Vol.47 No.2

<P>Bucillamine is used for the treatment of rheumatoid arthritis. This study investigated the protective effects of bucillamine against cisplatin-induced damage in auditory cells, the organ of Corti from postnatal rats (P2) and adult Balb/C mice. Cisplatin increases the catalytic activity of caspase-3 and caspase-8 proteases and the production of free radicals, which were significantly suppressed by pretreatment with bucillamine. Bucillamine induces the intranuclear translocation of Nrf2 and thereby increases the expression of γ-glutamylcysteine synthetase (γ-GCS) and glutathione synthetase (GSS), which further induces intracellular antioxidant glutathione (GSH), heme oxygenase 1 (HO-1) and superoxide dismutase 2 (SOD2). However, knockdown studies of HO-1 and SOD2 suggest that the protective effect of bucillamine against cisplatin is independent of the enzymatic activity of HO-1 and SOD. Furthermore, pretreatment with bucillamine protects sensory hair cells on organ of Corti explants from cisplatin-induced cytotoxicity concomitantly with inhibition of caspase-3 activation. The auditory-brainstem-evoked response of cisplatin-injected mice shows marked increases in hearing threshold shifts, which was markedly suppressed by pretreatment with bucillamine <I>in vivo</I>. Taken together, bucillamine protects sensory hair cells from cisplatin through a scavenging effect on itself, as well as the induction of intracellular GSH.</P>

복숭아나무 硬枝揷木時 揷木 用土와 基間이 發根과 圃場活着에 미치는 영향

林敬鎬,林炯基,金道翊,金月洙,鄭淳柱 全南大學校 農業科學技術硏究所 1998 農業科學技術硏究 Vol.33 No.-

복숭아나무 경지삽목 번식에 있어서 삽목 용토와 기간 및 삽수내 저장 양분 함량 변화 등이 발근과 포장 활착에 미치는 영향을 구명하였다. 삽목 용토는 vermiculite가 peat pellets 岩線보다 발근율, 발근수와 발근장 및 포장 활착율 등에 있어서 가장 좋은 효과를 나타냈다. 삽목 기간은 35일에서 55일로 기간이 길어질수록 발근율이 높고 뿌리 발달이 좋아졌으나, 포장 활착율은 삽수내전탄수화물과 전당 등 전당 등 저장양분 소비가 많아 삽목 기간이 짧은 35일에서 높았다. 특히 이들 양분 중에서 sucrose의 소비가 가장 많았다. 포장에서 활착후 수고, 간경 등 생육은 모든 처리에서 수고 136㎝, 간경 22.9㎜ 이상으로 삽목 당년에 우량묘가 생산되었다. This experiment was studied to examine the effect of cutting media and duration on rooting and transplanting using hardwood cutting of 'Sunaga Wase' peach to establish mass production system of rooted cutting. In cutting media, vermiculite showed higher root growth than peat pellets and rock-wool on rooting, root number, root length, and survival in field. The longer cutting duration was from 35 to 55 days, the better rooting and root growth obtained. But the transplanting was the best at 35 days, because it held enough storage nutrient including carbohydrate and sugar which were consumed in cutting stem tissue of 'Sunaga Wase' peach during hardwood cutting. Especially, among these nutrients, sucrose showed the highest consumption. After transplanting of rooted cutting to field, tree height and diameter of ' Sunaga Wase' peach was 136㎝ and 22.9㎜, respectively. therefore it could product the best quality of rooted cutting.

치아우식증 수복용 북합레진의 개발과 치아 적합성에 관한 연구 제1편 : 치과용 복합레진의 개발과 기계적 성질의 평가에 관한 연구

임호남,박상진,김형찬 大韓齒科器材學會 1992 대한치과재료학회지 Vol.19 No.2

An esthetic and permanent restorative materials that could be placed directly into the cavities prepared in anterior teeth would be an important contribution to dental practice and public well-being. This studies were planned to produce some experimental composite resins with the evaluation of literatures related to manufacture processes of it. It was assumed that through this studies we wish to get some fundamental data using for the domestic production of commercial dental composite resins with the confirmation of manufacturing process repoted by forein researchs, and to evaluate the physical properties of it. Summarized manufacturing process used in this studies include the synthesis of BIS-GMA inlaboratory, the silanization of fillers, and the its incorporation into prepared BIS-GMA resin to make two paste system. As a first research project, its usefulness as a composite resin and characteristics under the some experimental conditions were evaluated by the measurements of hardening time, compressive strength, diametral tensile strength, and elastic modulus, and the observation of surface using SEM. Following conclusions were drawn: 1. Concentration control of initiator and accelerator from 2% to 4% resulted the working time ranged from 0.33 minutes to 1.00 minute and the setting time from 1.66 minute to 5 minutes. 2. Compressive strength of unfilled resins was highest on KM-33 specimens, diametral tensile strength were decreased by rise of accelerator contents, but it was increased by the rised content of initiator. 3. Higher storage temperature made all of experimental resins became excellent ones. 4. By the incorporation of filler, resins become harder and stronger with the higher values of measurement, but it was decreased by the long term immersion in water. 5. Both of filled and unfilled resins showed the higher dimetral tensile strength over each allowable values of American Dental Specification.

Neural Oscillator를 이용한 강인한 피치추적에 관한 연구

임성길,김형호 대불대학교 2002 論文集 Vol.8 No.1

This Paper treats on the Method for robust pitch tracking on neural oscillator. We used the method which was modified LEGION(Locally Exitator Globally Inhibitory Oscillator Network) algorithm for neural oscillator. The proposed pitch tracking method was evaluated on a man and woman's clean voice which was recoded in the lab and news reporter's voice which has noice signal.

전국 응급의학과 수련병원의 응급실 병력지에 대한 분석

임태호,임훈,이종호,강형구,장문준,조광현,장석준,김승호,정상원 대한응급의학회 2000 대한응급의학회지 Vol.11 No.4

Background: This study was designed to analyze the current emergency department(ED) medical records of teaching hospitals in Korea. Methods: The five-item questionnaires were mailed to the EDs of 40 hospitals. Among them, 27 questionnaires and 35 ED medical records were returned for reply rates of 67.5% and 87.5%, respectively. Results: 1) The actual number of data elements in the ED medical records used by each hospital varies widely. It ranges from 1 to 15 data elements with an average of 7.5 data elements. 2) Thirteen data elements, signature of nurse, checklist style in review of systems, checklist style in physical examination, neurologic examination, figure of face, Glasgow coma scale, trauma scale, treatment plan, mode of transfer, condition on transfer, documents sent with patient, condition on discharge or discharge instruction, use of pediatric chart and vaccination history are used by less than 50% of the medical records examined. 3) There was no difference in the total number of data elements or in redesign and computerization of ED medical record based on the location of the hospital, the type of hospital administration, or the number of years since the start of EM residency program. 4) There was a statistically increased number of data elements in redesigned medical records. 5) In the survey, 89% of the residents replied that medical records needed to be redesigned. With respect to uniformity, 58% of the residents disagreed. A well-designed checklist chart rather than a descriptive chart was preferred by 89% of the residents. Conclusion: The currently used ED medical records have much room for improvement. The age of the ED had little impact on the quality of ED medical records. More attention and effort in this field are needed. In addition, The Korean Society of Emergency Medicine should provide guidelines for ED medical records.

위암수술 환자에서의 cp 개발과 cp적용에 따른 질 향상 활동에 관한 연구

임은주,황순휘,박도중,하광일,배현주,김형호 한국의료QA학회 2006 한국의료질향상학회지 Vol.13 No.2

Background : In an era of increasing medical costs, safe reduction in postoperative stay has become a major focus to optimize utilization of healthcare resources. The authors aimed to evaluate the clinical significance of the critical pathway(CP) for gastrectomy patients by implementing standardized postoperative management and electronic medical records. Method : From August 2006 to April 2007, critical pathways were introduced to inpatients and outpatients with gastric cancer. 60 consecutive patients undergoing distal gastrectomy were randomly divided into two groups; 30 CP group(A) and 30 non-CP group(B). Simultaneously, we also retrospectively reviewed the records of 438 patients(C:control group) who were able to be enrolled in CP program. We compared group(A) with (B), (C) in terms of hospital stay, complication rate, use of antibiotics and hospital costs. Patient satisfaction was surveyed by questionnaires. Result : There was no significant demographic difference between group(A) and (B). Of 30 patients in group(A), 5 drop-outs and 14 variances occurred. The mean postoperative hospital stays(Laparoscopy-assisted distal gastrectomy: LADG/Open distal gastrectomy: ODG) were 7.6/10.5 days for the group(A), 8.9/12.7 days for the group(B) and 12.6/14.5 days for the group(C) (p=0.02 in LADG). The total hospital cost of group(A) had a tendency to be less than that of group(B) and the amount of hospital cost per day in group(A) was significantly higher than that in group(B). The usage rates of the first generation antibiotics were 73.33%, 63.33%, and 59.2% in group(A), (B), and (C), respectively. Patients’ satisfaction had a tendency to be higher in the CP group than non-CP group. Conclusion : The mean hospital stay in LADG patients was shortened meaningfully and hospital cost per day was enlarged after introduction of clinical pathway. It is necessary to apply a number of patients to the critical pathway and to make an effort to reduce the variation and drop-out rates.

쾌속 3차원 조형 시스템을 활용한 장신구 제작방법의 개발

이호용,임중연,김경아,범형택 東國大學校 1998 東國論叢 Vol.37 No.-

This paper is concerned with the new production method for jewelry by using rapid prototyping system. this system can directly produce the three-dimensional prototype shape of jewelry based on CAD modeling. Recently, rapid prototyping technology has been regarded as a powerful concurrent tool for integrating design and manufacturing process. In view of this, our study focuses the attention on the new application of this technology into the prototype production of jewelry which has been manufactured almost by hand. The characteristics of various RP systems are presented and one distinct jewelry example has been produced to show that out method is quick and efficient.

만성 신부전증 환자의 중중 고혈당에 따른 의식 변화 결정에 대한 연구

위형중,이창범,박성광,강성귀,임천규,박은주,윤경택,한상웅,안유헌,김호중· 대한신장학회 2000 대한신장학회잡지 Vol.19 No.6

반복 용체화처리에 의해 조직제어된 Ti-6Al-4V 합금의 인장성질

조형준,임영호,이준희 동아대학교 공과대학 부설 한국자원개발연구소 1994 硏究報告 Vol.18 No.2

The purpose of the present study is to improve the tensile properties of the beta-quenched with little strain due to processing, only by heat treatment. Control of volume fraction, morphology and distribution of alpha is of great importance in achieving desired mechanical properties with a good combination of strength and elongation. Accordingly, a cyclic solution treatment has been proposed to obtain bimodal structures of equiaxed and acicular alphas. The microstructures of the specimens subjected to the Cyclic Ⅲ solution treatment consisted of nearly equiaxed and acicular alphas with the matrix of the tempered martensite. As a result, the tensile properties became almost equivalent to the specimens of the double solution treatment in the α+β region.