병렬기법을 이용한 RICS 프로세서용 고속 레지스터 파일 설계

박형근,김형균,김환용 圓光大學校大學院 1996 論文集 Vol.17 No.-

Modular memory is an essential component of any digital 1C design library. The major application of high speed register file has been as the main memory of large-scale computers, super computer, microcomputer, workstation, so on. So, in this thesis, The designed high speed register file for RISC processor, which is possible to processing concurrent I/O by seperating read/write bitline and word access TR has become one of the key embedded elements for processor VLSI's, because it allows simultaneous access from multiple resource and the parallel operations yield a high system throughput. Benefits include reduced constraints on the client units and simpler register to register programming models. Stable output characteristics was obtained by testing at peripheral circuits of operation and was designed by using 1.2[μm] CMOS design rule.

METRx™ 기구를 이용한 후방 경추부 추궁추간공 제거술의 예비 결과

박형천,윤승환,박종운,하윤,현동근,김은영,박현선,임대철 대한척추신경외과학회 2004 Neurospine Vol.1 No.1

Objectives: Posterior cervical microscopic laminoforaminotomy has been a preferred procedure for a posterolateral cervical disc or foraminal stenosis. However, neckpain from wide skin incision and muscle injury are some of disadvantages. The authors performed cervical microscopic laminoforaminotomy with METRx™ tubular dilator system and were compared the results with classical cervical microscopic foraminotomy. Methods: Six patients underwent posterior cervical microscopic laminoforaminotomy using the METRx™ during 6 months. We have selected 10 patients from our institution as a comparison group. Preoperative and postoperative pain score composed of the radicular and neck component was examined and disability score also recorded. Diameters and lengths of laminoforaminotomy on the postoperative CT also were compared with two methods Results: Postoperative pain scores to the radiculopathies were not different but postoperative pain scores to the neckpain on the follow up periods were significantly different. The average vertical and transverse diameters of the laminoforaminotomy defect on the postoperative CT scans were not different between two groups. Average hospital stay of the classical methods was 8.8±7.5 days comparison with 4.5±0.54days of new procedure. Conclusions: Posterior cervical microscopic laminoforaminotomy with METRx™ systems seems to provide similar decompression and clinical results as classical methods compared to classical methods and shows superior results for postoperative neckpain and hospital stays.

디지틀 이동통신용 동기추적 시스템의 의사잡음 부호 발생기 설계

박형근,김환용 圓光大學校大學院 1996 論文集 Vol.17 No.-

The study on the implementation of signal processing ASIC is advanced m the parts of the DS/CDMA using the direct sequence method which is better than any other type in the encryption aspect. Therefore, in this thesis, Pseudo Noise Code Generator suitable for the encryption aspect. Therefore, in this thesis, Pseudo Noise Code Generator of Code Tracking Sysytem for Digital Mobile Communication suitable for the DS/CDMA method including the additional characteristics for the spread spectrum signal processing technique, encryption technique which is protect to privacy between users, the decrease effects of the self-interference and transmission power spectral density, is designed to get the improved effects for the conventional (exciting) channel noise by using the Verilog-HDL.

요추부 수술후 통증관리를 위하여 실시한 Morphine Sulfate를 이용한 Caudal Block의 효과

윤승환,박형천,김은영,전병윤,이홍식,이성근 대한신경외과학회 1997 Journal of Korean neurosurgical society Vol.26 No.6

생물학적 유동층의 Media 충진량에 따른 미생물 농도 변화

김환기,최두형,박찬수 全北大學校 附設 都市및環境硏究所 1998 都市 및 環境硏究 Vol.13 No.1

The variation of microbiological concentration with packed volume of media was examined in the biological fludized bed which has swirl flow. The TOC and HRT of synthetic wastewater was kept with 70 ㎎/ℓ and 1.6 hr in the reactor, respectively. The mean grain size of sand as media was 0.397 mm and its volume was packed from 20 % to 60 % in the reactor. The experiment results from the above conditions were the treatment efficiency of 87.5 to 93.7 %, the MLVSS of 2,360 to 3,860 ㎎/ℓ, and the microbiological concentration per g-media of 8.4 to 17.3 ㎎/ℓ. The detailed results are as follows. 1) The continuous operation was possible in the biological fludized bed which has swirl flow, not existing fludized bed. 2) The whole microbiological concentration in the reactor was the highest at packing the media volume of 40 to 45 % and the microbiological concentration per g-media was the highest at packing the media volume of 25 %. In the viewpoint of SS, the best packing volume of media was 35 to 45 % in that the separation of microbes were the lowest. 3) From SEM photographs, it showed as that cocci and bacillus adhere to and grow on the media surface

뇌동맥류성 지주막하 출혈 후 지연허혈신경결함에 대한 평가에 있어서의 Acetazolamide단일광자방출전산화 단층촬영술의 역할

김형중,김은영,하윤,윤승환,박형천,박현선 The Korean Neurosurgical Society 2004 Journal of Korean neurosurgical society Vol.35 No.2

징병 신체검사에서 나타난 청소년기 추간반탈출증의 유병률과 임상적 특징 : A Study Based on Examinations for Conscription

홍창기,박철기,박형천,윤승환 대한척추신경외과학회 2004 Neurospine Vol.1 No.1

Objective: The authors analyzed the large series of intervertebral disc herniation in adolescence to evaluate the prevalence, clinical characteristics, and possible risk factors on the basis of the data from the examinations for conscription. Material and Methods: Of 77685 nineteen-old-males who were given an examination for conscription at Regional Military Manpower Administration of Seoul in 2002, 382 patients exempted from conscription due to intervertebral disc herniation were analyzed. The diagnosis were made from the medical certificate, medical record, magnetic resonance imaging(MRI)(or computed tomography(CT)) which examinee presented and confirmed with the aid of reexamination of CT. Radiological char cteristics and severity of intervertebral disc herniation as well as structural abnormalities of vertebral columns were carefully evaluated with CT scan and MRI scan. Possible risk factors like overweight, structural abnormality of vertebral column, trauma were analyzed statistically using one-sample T-test and chi - square test on the assumption that P value less than 0.05 was considered statistically significant. Result: Prevalence of intervertebral disc herniation in adolescence aged nineteen years and younger were 0.5%. L4-5 level was the most frequently affected site followed by L5-S1. Of all 382 patients of intervertebral disc herniation, 29% were considered serious with reference to radiological evidence of root compression or siginificant discogenic spinal stenosis. Limbus fracture was found in 6.8% of patients. Overweight was the significant risk factor of the disease(p=0.0). However, neither structural abnormality of vertebral column nor trauma showed any relation to pathogenesis of intervertebral disc herniation. Conclusion: In adolescence aged nineteen years and younger, the prevalence of intervertebral disc herniation was 0.5% and accompanying limbus fracture was more frequent when compared with adult. Overweight was the only significant risk factor of the disease.

베타-아밀로이드 펩타이드로 유발된 신경세포사와 tau 인산화와의 연관성

김지형,홍혜남,이종환,황승준,박형섭,이흥식,김동호 대한해부학회 1998 Anatomy & Cell Biology Vol.31 No.4

수완진동 증후군에서 신경장해의 조기진단을 위한 객관화된 방법

윤재국,이헌,최나리,김석환,박형욱,이지호,유철인 大韓産業醫學會 2009 대한직업환경의학회지 Vol.21 No.2

목적: 통각과 진동감각 역치검사 및 수부와 수지의 악력, 그리고 수지의 운동기능검사(태평) 등과 근로자들이 호소했던 증상에 대한 HAVS의 스톡홀름 워크샵 분류와의 관련성을 통해 좀 더 객관화된 신경학적 조기검사 방법을 찾고 타당성을 검증하고자 하였다. 방법: 2000년 1월부터 2007년 12월까지 수부진동에 폭로되고 수부의 불편함을 호소하여 진동 장해에 대한 검사를 시행한 497명의 근로자를 대상으로 하였다. 일차적으로 문진을 통해 직업력에 대해 알아보고 과거력을 조사했다. 대상자들의 스톡홀름 워크샵 분류에 따른 소견을 확인하고 수부의 말초 순환기능 검사(손톱압박, 수지피부 온도), 신경기능 검사(통각과 진동각 역치), 운동기능 검사(악력, 태평) 등을 시행하였다. 다른 질환의 감별을 위한 몇 가지 이학적 검사를 실시하고 스톡홀름 워크샵 분류에 따른 검사 결과들을 분석하였다. 결과: 사용 도구는 그라인더 단독 사용이 265명 (67.3%)으로 가장 많았으며 평균 노출 연수는 14.8년이었다. 통각과 진동감각에서 스톡홀름 워크샵 분류 단계에 따른 역치가 증가하는 경향을 보였으나 통각은 양측 모두 통계적인 유의성이 없었고, 진동감각은 125와 250 Hz에서 양측 모두 유의했다(p=0.006-0.038). 수부와 수지의 악력은 단계가 올라갈수록 감소하는 경향을 보였지만 수부와 수지 모두 우측에서만 통계적으로 유의했다 (p=0.041, p<0.01, p=0.034). 태평 첫수는 단계가 올라 가면서 전반적으로 태핑 첫수가 감소하였으며 좌측에서만 통계적으로 유의했다(p=0.002-0.019). 결론: 본 연구는 수부 진동 노출자들의 수부 불편함에 대한 신경계통을 초기에 정량적으로 객관화하여 진단할 수 있는 단일 방법은 아직 없으며 일상생활의 불편함과 스톡홀름 워크샵 분류 등을 통한 주관적인 증상에 더하여 수지 통각과 진동감각 역치검사, 수부와 수지 악력검사, 운동기능검사(태핑) 등을 통합하면 초기에 객관적으로 진단하는 것이 가능할 것으로 판단된다. Objectives: In order to determine find out the best methods for a more objective detection of neurologic abnormality in early hand ann vibration syndrome(HAVS), early with analyzing the validity of each of the detection methods was analyzed. We evaluated the relationships between the sensorineural stage of Stockholm-revised vibration syndrome classification and the results of several tests. Methods: 497 workers were investigated for symptom, exposure duration, the types of tools used, and medical history from January 2000 to December 2007. Pain sense threshold, vibrotactile threshold, hand grasp force, finger grasp force, and a finger tapping frequency test were performed by the workers. Results: The grinder(67.3%) was the most commonly used tool and the mean exposure duration was 14.8 years. Although the pain sense and vibrotactile threshold level tended to increase according to sensorineural stage of the Stockholm classification, there was statistically significant difference in the vibrotactile threshold of 125, 250 Hz (P=0.006~0.038) but not in the pain sense threshold. Hand and finger grasp force tended to decrease according to the sensorineural stage of Stockholm classification and there was statistically significant difference(P=0.041, <0.001, 0.034) only on the right hand side. The tapping frequency also generally decreased according to the sensorineural stage of the Stockholm classification and there was statistically significant difference (P=0.002~0.019) only on the left hand side. Conclusions: Although there is no single standardized method that can objectively diagnose the Sensorineural component of early HAVS early, the combination of subjective symptoms, the sensorineural stage of Stockholm classification, the pain and vibrotactile threshold test, the hand and finger grasp force, and the finger agility (tapping) test can objectively detect sensorineural component of HAVS early.

Antigenieity Study of CFA-001,Cefazolin,a Cephalosperin Derivative Produced by an Enzymatic Semisynthesis

Park, Jong Il,Han, sang seop,Jeong, Tae Cheon,Roh, Jung Koo,Kim, Hyoung Chin,Kim, Jeong Hwan,Jeon, Yeong Joong,Kim, Dal Hyun,Kim,Je Hak,Park, Kwan Ha 한국응용약물학회 1997 Biomolecules & Therapeutics(구 응용약물학회지) Vol.5 No.1

The antigenic potential of CFA-001, cefazolin, a cephalosporin derivative produced by an enzymatic semisynthesis, was determined in Hartley guinea pigs. A battery of tests employed consisted of active systemic anaphylaxis (ASA), passive cutaneous anaphylaxis (PCA), and indirect hemagglutination test (IHA). The results were as follows: 1) In ASA, no signs attributable to anaphylaxis was observed in guinea pigs sensitized with CFA-001, whereas OVA-sensitized animals induced severe anaphylactic symptoms; 2) guinea pigs did not produce antibodies against CFA-001 when sensitized with or without Freund's complete adjuvant (FCA) in homologous PCA tests. Meanwhile, antibodies against ovalbumin (OVA) were clearly detected; 3) No CFA-001-specific hemagglutination was observed in the IHA using sera obtained from CFA-001-sensitized guinea pigs. These results suggest that CFA-001 has no antigenicity potential in guinea pigs.