아로마테라피가 여대생의 생리통 및 월경곤란증에 미치는 효과 : A Blind Randomized Clinical Trial

한선희,노유자,허맹행 성인간호학회 2001 성인간호학회지 Vol.13 No.3

This study was designed to verify the effect of aromatherapy on menstrual cramps and dysmenorrhea by a quasi experiment (nonequivalent control group pretest-posttest design), from March to October, 2000. The subjects of this experiment consisted of 45 college women with menstrual cramps and dysmenorrhea. They were randomized by 25 for the experimental group and 20 for the control group. Their mean age was 20.6 years, mean menstrual period 28.7 days, mean menstrual cramps(VAS) 7.25, mean dysmenorrhea (Dysmenorrhea Scale) was 27.34. As treatment, aromatherapy was to give effleurrage of the abdomen with lavender, clary sage and rose as aroma oil, almond oil as carrier oil. For the control group, abdominal massage was given with only almond oil. Data collection included menstrual cramps, dysmenorrhea, the change of symptoms(low abdominal pain, lumbago headache, nausea, fatigue, edema). Menstrual cramps, dysmenorrhea and general, menstrual characteristics of subjects were measured the first day of the pre menstrual period before treatment (pre-test), menstrual cramps, dysmenorrhea, the change of symptoms were measured the first and second day of post menstrual period after treatment (posttest). Data were analyzed by t-test. χ2 - test, repeated measures ANOYA, Cronbach's α with SAS Program. The results of this study was as follows ; 1.Menstrual cramps was significantly lower in the experimental group(p = .001). 2.Dysmenorrhea was significantly lower in the experimental group(p = .027). 3.Less women in the experimental group complained about the six symptoms than women in the control group after treatment on the first day of the menstrual period(p〈 0.05. p 〈 0.01) In conclusion, these findings indicate that aromatherapy with lavender, clary sage, and rose could be effective to decrease menstrual cramps, and dysmenorrhea. So, aromatherapy could be applied to women suffering with menstrual cramps, dysmenorrhea periodically as an nursing intervention.

"지황 1호"를 이용한 숙지황 제조기술 연구

박남규,김선림,허한순,박충현 한국국제농업개발학회 2002 韓國國際農業開發學會誌 Vol.14 No.1

재래종 지황과 신육성품종 지황 1호를 이용하여 절단 및 원형으로 숙지황을 제조한 결과는 다음과 같다. 1. 가압에 의한 숙지황 제조시간이 재래종은 254∼264시간, 제품수율이 71.42∼71.48%였고, 지황 1호는 제조시간이 260∼276시간 소요되었고, 수율은 71.50∼71.51%였으며 중량은 감소하는 경향이었다. 2. 상압에 의한 숙지황 제조에서도 가압에 의한 제조와 비슷한 경향을 보였다. 3. 가압과 상압에 의한 숙지황 제조 후 유리당 조성은 재래종, 지황 1호 전처리구에 63∼65% 이상이 fructose였으며, 30% 이상이 glucose였고, sucrose, maltose가 함유되었다. 4. 가압 및 상압에 의한 숙지황 제조시 catalpol 함량 변화는 종자회수가 많아질수록 caltalpol 함량이 낮아지는 경향이었으나 완전히 없어지지는 않았다. 5. 숙지황 제조 후 포장재별로 포장하여 상온에 저장한 결과 제품에 곰팡이 발생이 없어 저장에 문제가 없었다. New processing method for R. Radix preparata was developed by using the landrace variety as a control and "Jiwhang 1" (Rehmannia glutinosa Liboschitiz). Sliced Rehmanna glutionsa Liboschitiz was steam heated by normal and high pressure conditions for the round-shaped R. Radix preparata processing. About 254 to 264 hours were required for the processing of domestic variety, and about 260 to 280 hours were required for "Jiwhang 1", but their yields were ranged about 71.42∼71.6%. Fructose and glucose were major free sugar of R. Radix preparata, and their composition rates were 63∼65% and 30%, respectively, but sucrose and maltose were traced only small amount. The Catalpol content was decreased as increasing the frequencies of steam heating repetion. But the catalpol was not completely removed. After processing, R. Radix preparata packed with paper-bag or PE-bag, and storaged at common temperature was keeping a best quality.

Carcinoembryonic antigen levels of tumor-draining venous blood as a prognostic marker in colon cancer

Sun Hyung Choi,Seung Yoon Yang,Yoon Dae Han,Min Soo Cho,Hyuk Hur,Kang Young Lee,Nam Kyu Kim,Byung Soh Min 대한종양외과학회 2017 Korean Journal of Clinical Oncology Vol.13 No.2

Purpose: Carcinoembryonic antigen (CEA) is a tumor marker for colorectal cancer (CRC) related to recurrence and prognosis. We examined the ability of the CEA level measured directly from a tumor drainage vein (dCEA) to predict the prognosis of CRC more accurately than those from a peripheral vein (pCEA). Methods: Fifty-two patients who received curative resection for colon adenocarcinoma were enrolled. The patients were categorized into two groups according to normal pCEA (<5.9425 ng/mL, n=24) or elevated pCEA levels (≥5.9425 ng/mL, n=28). Blood was sampled at the time of surgery simultaneously from the tumor drainage vein and from the peripheral vein. Results: The clinicopathologic variables showed no significant difference between the two groups. Patients with dCEA levels <20.192 ng/mL showed better disease-free (P=0.009) and overall survival (P=0.033) curves than those with dCEA levels ≥20.192 ng/mL. Elevated dCEA levels were a significant prognostic factor for overall survival and disease-free survival in Cox proportional hazard model analysis (hazard ratio [HR]=399; 95% confidence interval [CI], 16.4.9,747; P<0.001; HR=9.39, 95% CI, 1.29.68.006; P=0.026). In subgroup analysis, we compared the data of normal range of dCEA group and elevated dCEA group with normal pCEA; the overall survival rate of patients with normal dCEA was better and the disease-free survival rate was significantly better (P=0.003). Conclusion: CEA levels from a tumor drainage vein can be used as more accurate prognostic markers than levels from a peripheral vein in patients with colon cancer.

Guideline on specification and test methods information for HPV DNA chip new drug application

Sun-Young Baek,Kyung-Ho Han,Sook-Jin Hur 한국생물공학회 2007 한국생물공학회 학술대회 Vol.2007 No.4

화학적 손상에 따른 간 재생의 '간 조상세포' 동태에 관한 연구

허방,박명선,윤명희,이충한 고신대학교 의학부 2004 高神大學校 醫學部 論文集 Vol.19 No.1

Background: Oval(OV) cells had been described as an uncertain type of cells in early neoplastic process of animal hepatocarcinogenesis model. Although biological significance of OV cells is not elucidated in human, they showed cholangiolar and hepatocytic bipotential differentiation in animals, especially rodents. With recent studies emphasizing on a possible target of gene therapy and cell transplantation of hepatic stem cells, biological investigation of OV cells become to be an important issue. In present study, the authors pursue the fate of hepatic stem cell progenitor cells such as OV cells using 2-acetylaminofluorene (AAF)/partial hepatectomy (PH) of resistant hepatocyte(RH) model.Materials & Methods: Through gastrostomy tube, 2-AAF (10㎎/㎏)was administrated daily for 10 days in SD rats. Seventy percent PH was preformed at 5th day of 2-AAF treatment. Animals were killed 1,3,5,7,9 and 14 days following the last day of 2-AAF. Bromodeoxyuridine (BrdU) (100㎎/㎏) was given intraperitoneally 1 hour before killing in each experiment. Hematoxylin eosin-stained histological sections and morphometric changes were analysed by microscope (Americal Optical microStar) with right angle section of portal regions by means of unit areas of high power view. For BrdU incorporation, the sections were immunostained by an anti-BrdU antibody and labelled nuclei were counted. For electron microscopy, fresh liver tissues fixed with 2% glutaraldehyde were processed by routine method. Results:1) It was confirmed that periportal OV cells are a major component of AAF/PH-induced hepatic regeneration based on OV cell proliferation in concord with restoration of liver weight. 2) With BrdU incorporation, OV cell proliferative activity migrates toward pericentral zone from periportal zone. 3) OV cells show bile ductular differentiation with progressive regression and later hepatocytic differentiation through basophilic small hepatocytic transition. 4) In contrast to OV cells, basophilic small hepatocytic emerged from periphery of OV cell proliferative zone in late period of regeneration, inspite of independent pericentral localization of small proportion. 5) Ultrastructurally 3 type of OV cells, at least, were noted in peripotral proliferative zone: predominant biliary differentiated cells, sparce undifferentiated small cells and hepatocytic hepatocytic transitional cells. 6) Colonized hematopoietic cells with a few blast-like cells were noted following OV cell proliferation chiefly in areas of periphery of OV cell proliferative zone. Conclusions: It was confirmed that AAF/PH is a hepatic regeneration model through OV cell proliferation. In this model, hepatic regeneration could be accomplished with periportal OV cell proliferation and subsequent hepatocytic differentiation via small basophilic hepatocytic transition, in addition to a possible role of extramedullary hematopoietic cells.

Effects of Dietary Glycine Betaine on Pork Quality in Different Muscle Types

Hur, Sun Jin,Yang, Han Sul,Park, Gu Boo,Joo, Seon Tea Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.11

This study was conducted to determine the effects of dietary glycine betaine on pork quality in different muscle types. A total of 80 female pigs ($Landrace{\times}Yorkshire{\times}Duroc$) were randomly allotted into one of four experimental diet groups. Each group of pigs were fed a commercial diet (Control) with 0.2 g glycine betaine (T1), 0.4 g glycine betaine (T2) and 0.6 g% glycine betaine (T3)/kg for 40 days. pH of belly was significantly higher in the control than dietary glycine betaine groups at 13 days of storage, whereas pH of picnic shoulder and ham were significantly lower in control than glycine betaine groups. At 13 days of storage, redness (a*) of belly was significantly higher in control than dietary glycine betaine groups, whereas picnic shoulder and ham were significantly higher in glycine betaine groups than in the control. Water-holding capacities (WHC) of all muscle samples were significantly higher in the control than glycine betaine groups until 5 days of storage. Sarcomere length was significantly longer in the control than glycine betaine groups. The thiobarbituric acid reactive substances (TBARS) value of belly was much higher than other muscle types at 13 days of storage. In fatty acid composition, dietary glycine betaine increased the ratio of saturated fatty acids (SFA) and decreased unsaturated fatty acids (USFA) in loins.

Effect of Dietary Conjugated Linoleic Acid on Lipid Characteristics of Egg Yolk

Hur, Sun-Jin,Kang, Geun-Ho,Jeong, Jin-Yeun,Yang, Han-Sul,Ha, Yeong-Lae,Park, Gu-Boo,Joo, Seon-Tea Asian Australasian Association of Animal Productio 2003 Animal Bioscience Vol.16 No.8

A total of 250 laying hens were fed a diet containing 0, 1, 2.5 or 5% conjugated linoleic acid (CLA), and 5% Safflower seed oil (SSO) for 5 weeks, and eggs were collected by week to analyse lipid characteristics of egg yolk. Egg yolk from CLA-fed groups showed significant increase in CLA content with increased CLA in the diet. Dietary CLA also increased the ratio of saturated fatty acids and decreased unsaturated fatty acids in the egg yolk. The proportion of myristic, palmitic, stearic and CLA were increased, while those of oleic, linoleic, linolenic and arachidonic acid were decreased. The cholesterol content in egg yolk was significantly decreased by dietary CLA for 5 weeks feeding. After 7 days of feeding, 5% CLA-fed group showed the lowest cholesterol content in egg yolk. CLAfed groups showed significantly lower 2-thiobarbituric acid-reactive substances (TBARS) values compared to control and SSO-fed group after 14 days of storage. No significant differences in TBARS values among CLA-fed groups were observed at the 28 days of storage. Results suggested that lipid oxidation of egg yolk during cold storage could be inhibited by dietary CLA due not only to changes in fatty acid composition but also to the high concentration of CLA in egg yolk.

가시오갈피의 생리·생태적 특성 (Ⅰ) : 산지별 순광합성, 기공증산, 기공전도도 Net Photosynthetic Rates, Stomatal Transpirations, Stomatal Conductances of Leaves

한상섭,권정중,이갑연,허성두,김하선,김종원 江原大學校 森林科學硏究所 2003 Journal of Forest Science Vol.19 No.-

이 연구는 가시오갈피 엽의 생리적 특성을 밝히고자 광합성, 기공증산, 기공전도도의 생리반응을 측정한 것으로 결과를 요약하면 다음과 같다. 1. 광보상점은 양엽이 약 30 μ mol m^(-2) s^(-1), 음엽이 약 15 μ mol m^(-2) s^(-1) 이었다. 2. 광포화점은 양엽이 약 1,000 μ mol m^(-2) s^(-1), 음엽이 약 300 μ mol m^(-2) s^(-1) 이었다. 3. 우리나라 및 중국산 가시오갈피 상엽의 순광합성속도는 약 8.0-8.8 μ mol m^(-2) s^(-1) 로 산지간에 유의차가 인정되지 않았다. 제주산 섬가시오갈피 상엽은 약 6.9 μ mol m^(-2) s^(-1) 로 다소 낮았다. 4. 모든 산지에서 중위엽의 순광합성속도는 상엽의 40-65%, 하위엽은 상엽의 30% 정도이었다. 그러나 섬가시오갈피 하엽은 상엽의 약 71%로 다소 높았다. 5. 상엽의 기공증산속도는 1.1-1.4 mmol H₂O m^(-2) s^(-1), 중위엽은 0.7-1.0 mmol H₂O m^(-2) s^(-1), 하위엽은 0.5-0.6 mmol H₂O m^(-2) s^(-1)로 산지별로 유의차가 없었다. 6. 기공전도도는 상엽이 약 70-90 mmol H₂O m^(-2) s^(-1)로 산지별 유의차가 인정되지 않았다. 그러나 제주 섬가시오갈피 상엽은 약 380 mmol H₂O m^(-2) s^(-1)로 타산지보다 현저히 높았다. This study was made on the physiological reactions of photosynthesis, stomatal transpiration, stomatal conductance of Acanthopanax senticosus of leaves. The resuits obtained are as follows : 1. The light compensation points were approximately 30μ㏖ m^(-2)s^(-1) in sun leaves and 15μ㏖ m^(-2)s^(-1) in shade leaves. 2. The light, saturation points were approximately 1,000μ㏖ m^(-2)s^(-1) in sun leaves and 300μ㏖ m^(-2)s^(-1) in shade leaves. 3. There was no significant between various mountains distributed, net photosynthetic rates were approximately 8.0 to 8.8μ㏖ m^(-2)s^(-1) in upper leaves. However, net photosynthetic rate in upper leaves of Acanthopanax koreanum in Jeju island was slightly low about 6.9μ㏖ m^(-2)s^(-1). 4. Net photosynthetic rate in middle leaves of all mountains was ranged from 40% to 65% of upper leaves, and that in lower leaves was approximately 30% of upper leaves. But, the net photosynthesis in lower leaves of Acanthopanax koreanum in Jeju island was slightly high about 71% of upper leaves. 5. There was no significant between various mountains distributed, stomatal transpirations were ranged from 1.1 to 1.4 mmol H₂Om^(-2)s^(-1) in upper leaves, 0.7 to 1.0 mmol H₂O m^(-2)s^(-1) in middle leaves, and 0.5 to 0.6 mmol H₂0m^(-2)s^(-1) in lower leaves, respectively. 6. There was no significant between various mountains distributed, the stomatal conductance in upper leaves was ranged from 70 to 90 mmol H₂O m^(-2)s^(-1) . However, stomatal conductance in upper leaves of Acanthopanax koreanum in Jeju island was approximately 380 mmol H₂O m^(-2)s^(-1), its remarkedly higher than any other mountain.

선박의 자세 안정성 향상을 위한 Anti Heeling System 구동용 100㎾급 매입형 영구자석 전동기의 설계 및 특성해석

이선권(Sun Kwon Lee),강규홍(Gyu Hong Kang),김영한(Young Han Kim),김형규(Hyung Kyu Kim),허진(Jin Hur) 대한전기학회 2010 대한전기학회 학술대회 논문집 Vol.2010 No.10

본 논문에서는 선박의 자세안정성 향상을 위한 Anti heeling system 구동용 100㎾급 매입형 영구자석 전동기의 설계 및 해석결과를 기술한다. 선박의 요구 조건을 반영한 목표사양 및 size를 도출하고, 선박적용을 위한 설계 프로세서를 제안하였다. 선박적용을 위해 설계단계부터 고려해야할 내용을 검토하였다. 등가자기회로법과 유한요소법을 이용한 자기회로설계결과와 토크특성해석을 실시한 결과를 기술하였다.

전북지역 양돈장에서의 돼지 부종병 항체 및 톡신 양성률 조사

조선영 ( Sun-young Cho ),유정희 ( Jeong Hee Yu ),유영주 ( Yeong Ju Yu ),이한준 ( Han-jun Lee ),허진 ( Jin Hur ) 한국동물위생학회 2023 韓國家畜衛生學會誌 Vol.46 No.4

Edema disease (ED) in pigs is enterotoxemia caused by Shiga toxin type 2e (Stx2e)-producing Escherichia coli (STEC) and frequently occurs in young piglets. Therefore, ED causes enormous economic losses in pig farms. In this study, a modified Stx2e (mStx2e) antigen was expressed and purified using commercial E. coli expression system. Monoclonal antibody was serviced by Ynto Ab Inc., using Phage Display Technique. Anti-Stx2e antibodies in piglets were measured by indirect ELISA using mStx2e antigens. Naive Stx2e in piglets were detected by Sandwich ELISA using Stx2e-monoclonal antibodies and commercial Stx2e-polyclonal antibodies. Among 3,480 piglets, anti-Stx2e antibodies were observed in 2,573 piglets. The 49.4% among 830 piglet serum samples possessed 0.625 mg/mL or more of Stx2e proteins. The 18.3% of 830 sera had 0.313 mg/mL of Stx2e proteins. The 32.3% of 830 samples held 0.156 mg/mL or less of Stx2e proteins. These results show that indirect ELISA using mStx2e antigen and Sandwich ELISA using Stx2e-monoclonal and polyclonal antibodies can be useful to detect ED in piglets.