간경변 환자의 정맥류 출혈에서 Octreotide의 지혈효과

권운용,정중식,김규석,김성혜,신상도,이중의,서길준,윤여규 대한응급의학회 2001 대한응급의학회지 Vol.12 No.1

Purpose: This study was conducted to confirm the effects of octreotide in patients with variceal bleeding. Methods: We performed a retrospective analysis of 26 patients with variceal bleeding, who visited the Emergency Center of Seoul National University Hospital from January 1st to June 31st,1996, the control group, and a prospective analysis of 28 patients with variceal bleeding, who visited the Emergency Center of Seoul National University Hospital from March 1st to August 31st, 1999, for the octreotide-infused group. The octreotide-infused group recieved a continuous infusion of octreotide, 25㎍/hr, for 5 days after an initial bolus of 50 ㎍. When active bleeding continued over 1 hour, over 5 pints of packed-RBC were needed for transfusion within 24 hours, or when the systolic blood pressure was under 90mmHg, a ballon tamponade with Sengstaken-Blackemore tube was used. T-test and X2 test were used for statistic at analysis (p<0.05). Results: Forty-one patients were male(octreotide-infused group 22, control group 19) and 13 were female(octreotide-infused group 6, control group 7). The mean age was 55 years(octreotide-infused group 56 years, control group 52 years). There were no significant differences in vital signs, hemoglobin/hematocrit levels, and Child-Pugh's classifications between the octreotide-infused group and the control group initially. There was a significant difference in the rates of early bleeding control within 24 hours(p<0.05), but there were no significant differences in the rates of rebleeding, mortality within 1 week, and use of a balloon tamponade. Conclusion: Variceal bleeding is a serious complication of liver cirrhosis and has a high mortality rate. Octreotide is an effective vasoactive agent for control of early bleeding, Thus, octreotide should be used first before endoscopic definitive therapies, to stabilize the vital signs of patients and to secure a field for endoscopic procedures.

ASP방식의 ERP 도입 및 이용의 핵심성공요인에 관한 연구 : 중소제조업체를 중심으로

권순동,정중식 한국정보기술응용학회 2006 Journal of information technology applications & m Vol.13 No.3

발열이 있는 호중구 감소증 환자에서의 위험도 예측인자

정중식,권운용,김규석,임용수,이중의,서길준,윤여규 대한응급의학회 2000 대한응급의학회지 Vol.11 No.3

Background: Most febrile neutropenic patients are treated in an aggressive manner. However, identification of low-risk patients may enable clinicians to administer risk-based treatment. The object of this study is to certify the factors associated with increased risk at the time of visiting the emergency department. Methods: This is a retrospective study. We reviewed the medical records of 101 febrile neutropenic patients who had visited the emergency department of Seoul National University Hospital from January 1998 to August 1999. We assumed 22 risk prediction factors that could be assessed at admission to the emergency department and 5 factors that could be assessed during treatment course. To find independent risk-prediction factors, we analyzed these factors respectively by using multiple regression analysis. Results: Tachycardia(aOR=136.5), altered mentality(aOR=28.8), decreased renal function(aOR=20.1), and significant comorbidity(aOR=17,2) are the independent factors associated with higher mortality. Altered mentality(aOR=31.6) and decreased renal function(CCr < 75㎖/min, aOR=5.4) are those associated with a higher incidence of septic shock. Independent factors associated with persistent(more than 3 days) fever are the early(within 10 days) onset of fever after last chemotherapy(aOR=8.8) and the existence of new pulmonary infiltrates on a simple chest X-ray(aOR=4.3). Conclusion: The stability of vital signs, the change of mentality, the renal function, the existence of significant comorbidity, the existence of new pulmonary infiltrates, and the rate of neutropenia are clinically useful risk-prediction factors in febrile neutropenia at the time of visiting the emergency department.

Interface between Robot and Scanner for Remote Laser Welding System Based on Time Synchronization

김정중,이준우,이주장,권경업,강희신,서정,Kim, Jeong-Jung,Lee, Joon-Woo,Lee, Ju-Jang,Kwon, Kyung-Up,Kang, Hee-Shin,Suh, Jeong Korean Society of Laser Processing 2013 한국레이저가공학회지 Vol.16 No.1

Remote laser beam welding (RLW) has the benefits of high speed and high quality welding, especially as applied to automotive industry. RLW is designed in a way that end effecter and head of scanner move simultaneously, and require the compensation for the motion of end effecter in order to weld proper position. In this paper, we show the algorithms of RLW that enable the end effecter to synchronize with scanner based on time. The proposed method consists of two algorithms. These algorithms make it possible for the moving end effecter to weld on desired place. The effectiveness of the algorithms is shown by experiments. 원격레이저 용접은(RLW)은 고속으로 고품질의 용접을 가능하게 하고 특히 자동차산업에 적용할 때 그 장점이 발휘된다. RLW은 로봇의 말단과 스캐너가 동시에 움직이도록 설계되는데 적합한 위치에 용접을 하기 위해서는 말단의 움직임에 대한 보상이 이루어져야 한다. 본 논문에서는 스캐너와 말단을 시간에 기반하여 동기화 하는 RLW을 위한 알고리즘을 보인다. 제안된 알고리즘은 두 개의 알고리즘으로 구성되어 있고 본 알고리즘으로 움직이는 말단이 원하는 위치에 용접을 가능하게 한다. 제안된 알고리즘의 효용성은 실험을 통해 보인다.

Paraquat중독에서 Vitamin C의 항산화성 효과에 관한 연구

김성혜,정중식,권운용,이중의,서길준,정성은,윤여규 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.3

Background : Paraquat is widely used herbicide. But if it is ingested by accident or by suicidal attempt it causes severe toxicity. And in emergency room, it is a big problem that there is no effective treatment modality for paraquat intoxication. It is reported that the mechanism of toxicity is by oxygen free radical. And Vitamin C is known as potent antioxidant. This study was designed to evaluate the antioxidant effect of Vitamin C to lipid peroxidaton in paraquat intoxication. Methods : 24 rats were divided to 6 groups after paraquat injection(20mg/kg), and each group has 4 rats. In 2 control groups we only observed until 6hours and 24hours. And Vitamin C of 10 mg per kilogram body weight on the low dose group and 100 mg per kilogram body weight on the high dose group were injected simultaneously. And in 6hours group, after 6hours of paraquat and vitamin C injection biochemical levels of malondialdehyde, superoxide dismutase and catalase were measured in liver and lung. And in 24 hours group after 24 hours the same measures were done. The stasistical methods used were ANNOVA and Mann-Whitney test and P-value was 0.05. Results : Malondialdehyde level of high dose Vitamin C group was significantly low compared to that of the control groups in liver tissues after 24hours(p<0.05). And in lung tissues both low dose and high dose vitamin C groups show significantly low level of malondialdehyde level after 24hours(p<0.05). On the superoxide dismutase activity, only high dose Vitamin C group shows significantly high level in 24hours both in liver and lung tissues. And the catalase activity is significantly elevated in high dose Vitamin C group after 24hours both in liver and lung tissues.(p<0.05) Conclusion : High dose Vitamin C suppresses lipid peroxidation, increases catalase activity and superoxide dismutase activity in paraquat intoxiation. It is thought to by antioxidant effect of vitamin C but it's effect is observed only in 24hours after intoxication.

가시오갈피의 생리·생태적 특성 (Ⅰ) : 산지별 순광합성, 기공증산, 기공전도도 Net Photosynthetic Rates, Stomatal Transpirations, Stomatal Conductances of Leaves

한상섭,권정중,이갑연,허성두,김하선,김종원 江原大學校 森林科學硏究所 2003 Journal of Forest Science Vol.19 No.-

이 연구는 가시오갈피 엽의 생리적 특성을 밝히고자 광합성, 기공증산, 기공전도도의 생리반응을 측정한 것으로 결과를 요약하면 다음과 같다. 1. 광보상점은 양엽이 약 30 μ mol m^(-2) s^(-1), 음엽이 약 15 μ mol m^(-2) s^(-1) 이었다. 2. 광포화점은 양엽이 약 1,000 μ mol m^(-2) s^(-1), 음엽이 약 300 μ mol m^(-2) s^(-1) 이었다. 3. 우리나라 및 중국산 가시오갈피 상엽의 순광합성속도는 약 8.0-8.8 μ mol m^(-2) s^(-1) 로 산지간에 유의차가 인정되지 않았다. 제주산 섬가시오갈피 상엽은 약 6.9 μ mol m^(-2) s^(-1) 로 다소 낮았다. 4. 모든 산지에서 중위엽의 순광합성속도는 상엽의 40-65%, 하위엽은 상엽의 30% 정도이었다. 그러나 섬가시오갈피 하엽은 상엽의 약 71%로 다소 높았다. 5. 상엽의 기공증산속도는 1.1-1.4 mmol H₂O m^(-2) s^(-1), 중위엽은 0.7-1.0 mmol H₂O m^(-2) s^(-1), 하위엽은 0.5-0.6 mmol H₂O m^(-2) s^(-1)로 산지별로 유의차가 없었다. 6. 기공전도도는 상엽이 약 70-90 mmol H₂O m^(-2) s^(-1)로 산지별 유의차가 인정되지 않았다. 그러나 제주 섬가시오갈피 상엽은 약 380 mmol H₂O m^(-2) s^(-1)로 타산지보다 현저히 높았다. This study was made on the physiological reactions of photosynthesis, stomatal transpiration, stomatal conductance of Acanthopanax senticosus of leaves. The resuits obtained are as follows : 1. The light compensation points were approximately 30μ㏖ m^(-2)s^(-1) in sun leaves and 15μ㏖ m^(-2)s^(-1) in shade leaves. 2. The light, saturation points were approximately 1,000μ㏖ m^(-2)s^(-1) in sun leaves and 300μ㏖ m^(-2)s^(-1) in shade leaves. 3. There was no significant between various mountains distributed, net photosynthetic rates were approximately 8.0 to 8.8μ㏖ m^(-2)s^(-1) in upper leaves. However, net photosynthetic rate in upper leaves of Acanthopanax koreanum in Jeju island was slightly low about 6.9μ㏖ m^(-2)s^(-1). 4. Net photosynthetic rate in middle leaves of all mountains was ranged from 40% to 65% of upper leaves, and that in lower leaves was approximately 30% of upper leaves. But, the net photosynthesis in lower leaves of Acanthopanax koreanum in Jeju island was slightly high about 71% of upper leaves. 5. There was no significant between various mountains distributed, stomatal transpirations were ranged from 1.1 to 1.4 mmol H₂Om^(-2)s^(-1) in upper leaves, 0.7 to 1.0 mmol H₂O m^(-2)s^(-1) in middle leaves, and 0.5 to 0.6 mmol H₂0m^(-2)s^(-1) in lower leaves, respectively. 6. There was no significant between various mountains distributed, the stomatal conductance in upper leaves was ranged from 70 to 90 mmol H₂O m^(-2)s^(-1) . However, stomatal conductance in upper leaves of Acanthopanax koreanum in Jeju island was approximately 380 mmol H₂O m^(-2)s^(-1), its remarkedly higher than any other mountain.

유리섬유보강 폴리머 복합패널의 피로특성 : Fatigue Properties of Glass Fiber Reinforced Polymer Composite Panel

연규석,정중호,권택정,김성기 강원대학교 부설 석재복합신소재 제품연구센터 2004 석재연 논문집 Vol.9 No.-

본 연구는 압축강도 1,020 kgf/㎠를 갖는 폴리머 모르타르를 중심부로 하고 내·외표면은 고인장의 GF RP로 보강된 샌드위치 패널의 피로 특성에 관한 연구이다. 이를 위해 중심부 폴리머 모르타르와 압축 및 인장측 GERP보강층 두께를 달리하는 샌드위치 형식의 패널 시험체를 제작하고 이에 대한 휨 피로 시험을 수행함으로써 폴리머 모르타르 두께와 GFRP보강층 두께가 패널의 휨피로거동에 미치는 영향 즉 피로하중수준-피로수명과의 상관관계를 구명하였다. 실험결과 하중수준이 증가함에 폴리머 모르타르 및 GFRP 보강두께에 관계없이 샌드위치 패널의 피로수명은 감소하는 경향을 나타냈고, 동일 하중수준에서는 폴리머 모르타르 두께가 증가함에 따라 피로수명은 감소하는 경향을 나타냈으며, GFRP 보강층 두께가 증가함에 따라 피로수명이 증가하는 경향을 나타냈다. 한편 이러한 폴리머 모르타르 및 GFRP 보강층 두께에 따른 피로응력수준-피로수명 상관관계는 수정된 Miner의 법칙과 부합됨을 확인 할 수 있었다. Is this study, the fatigue properties of the sandwich panel of which core was made of the polymer mortar and inner and outer facings were reinforced by a high-tensile GFRP were surveyed. Sandwich-panel specimens consisted of polymer mortar core and GFRP compressive and tensile sides with various thickness were produced for the experimental study. Flexural fatigue tests were conducted to figure out the correlation between fatigue load and fatigue life for various thickness of core and facings, and its results are presented. The correlation obtained in this study between fatigue load and fatigue life for various thickness are in good agreement with the modified Miner's law.

거푸집 개발용 GFRP보강 폴리머 복합패널의 휨 특성

연규석,권택정,정중호,김성기 강원대학교 부설 석재복합신소재 제품연구센터 2004 석재연 논문집 Vol.9 No.-

본 연구는 반영구수명의 교량상판용 영구거푸집을 개발할 목적으로 리브를 갖는 GFRP보강 폴리머 콘크리트 복합패널을 제작하고 이에 대한 휨특성을 고찰한 것이다. 연구에서 리브높이와 인장측 GFRP보강층 두께를 달리하는 12종류의 GFRP보강 폴리머 콘크리트 복합패널 시험체를 제작하고 이에 대한 휨시험을 수행함으로써 리브 높이와 GFRP보강층 두께가 복합패널의 휨특성에 미치는 영향을 실험적으로 구명하였다. 시험결과 GFRP보강 폴리머 콘크리트 복합패널의 극한 모멘트는 GFRP 보강두께가 증가 1.0에서 4.0 mm로 증가 할때, 리브 높이에 관계없이 약 93~101%의 거의 일정한 중가폭을 보였고, 리브 높이가 1.0에서 3.0cm로 증가할 때, GFRP 보강층 두께에 관계없이 약 35~41%의 거의 일정한 증가폭을 보였다. 또한 강도설계법에 기초한 극한모멘트 예측식은 실험결과와 잘 부합되어 리브를 갖는 GFRP 보강 폴리머 콘크리트 복합패널을 영구거푸집에 적용할 시 지간에 따른 상용 단면설계에 매우 유용하게 적용될 것이다. In this study, twelve different GFRP-reinforced polymer concrete composite panel specimens with various rib heights and tensile side and reinforced side thickness were produced. flexural tests were conducted to figure out the effect of the height and thickness influencing on the flexural properties of composite panel. Test results of the study are presented. Especially, a prediction equation of the ultimate moment based on the strength design method agrees well with the test results, and it is thought to be useful for the corresponding design of cross-section according to various spans as the GFRP-reinforced polymer concrete composite panel is applied for a permanent form.

죽상동맥경화에 의한 말초혈관 폐쇄성 질환에 있어서 Angiotensin-Converting Enzyme 유전자 Insertion/Deletion과 E-selectin 유전자 S128R의 다형성

정금오,권정남,박동은,김정중,문형배,소병준 대한외과학회 2004 Annals of Surgical Treatment and Research(ASRT) Vol.66 No.6

세라믹분말을 혼입한 SBR,PAE 폴리머 시멘트 페이스트의 기초적 성질

연규석 ( Yeon Kyu-seok ),권택정 ( Kweon Taek-jeong ),정중호 ( Jeong Jung-ho ),김성기 ( Jin Xing-qi ),주명기 ( Joo Myung-ki ) 한국농공학회 2004 한국농공학회 학술대회초록집 Vol.2004 No.-