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Niu, Xiaoye,Chen, Zhili,Wang, Haizhen,Chen, Zhifu,Zhang, Lifeng,Niu, Guojun,Hong, Hui,Xin, Ying 대한전기학회 2014 The Journal of International Council on Electrical Vol.4 No.2
Superconducting fault current limiter (SFCL) is a kind of short-circuit current limiting device for power grid. It's a new application of superconducting technology on power equipments. Saturated Iron-core Superconducting fault current limiter (SISFCL) is one of many types of SFCL. It takes the advantage that no quenching occurs in superconducting wires during fault current limiting process. The immediately reacting and fast recovering are also its main characteristics. The structure and function of SISFCL is similar to that of traditional transformer and current limiting reactor respectively. Based on mature technologies on design and manufacture of iron core and windings of transformers, SISFCL could be made at the same voltage level as traditional transformers. But there are also significant differences between them. SISFCL will offer an effective solution to limit short-circuit current in future HV or EHV power systems because of its peculiar structures and properties. In this paper, we introduce the structure and characteristics of the SISFCL developed by Innopower. It may help readers to understand SISFCL and its enormous application value for power grids.
Niu, Hui-Yan,Niu, Chun-Ying,Wang, Jia-He,Zhang, Yi,He, Ping Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.8
Background: Breast cancer is one of the most common cancers in women in the world. Health-related quality of life (HRQL) at treatment endpoint in cancer clinical trials is widely considered to be increasingly important. The aim of this review was to provide a literature-based assessment of the validity, reliability and responsiveness of breast cancer-specific HRQL instruments in women breast cancer patients. Materials and Methods: The databases consulted were Medline, PubMed, and Embase. The inclusion criteria required studies to: (1) involve use of HRQL measures; (2) cover women with breast cancer under standard treatment (surgery, radiation therapy, chemotherapy, hormone therapy, and targeted therapy); (3) involve the validity, reliability, or responsiveness of HRQL; (4) deal with validation of breast cancer-specific HRQL instruments. Results: A total of 16 studies were identified through the literature search that met the 4 inclusion criteria. Some seven instruments were assessed among these 16 studies: EORTC QLQ-BR23, FACT-B, FACT-ES, HFRDIS, LSQ-32, QLICP-BR, and SLDS-BC. EORTC QLQ-BR23, FACT-B, LSQ-32, QLICP-BR, and SLDS-BC are more general breast cancer-specific HRQL instruments. FACT-EB is the endocrine subscale combined with FACT-B in order to measure the side effects and putative benefits of hormonal treatment administered in breast cancer patients. HFRDIS is the HRQL measure focusing on hot flash concerns. Conclusions: This paper provides an overall understanding on the currently available breast cancer-specific HRQL instruments in women breast cancer patients.
Deep dechlorination of hydrocarbon oil by reactive adsorption on TiO2-based metal oxides
Hui Niu,Yuyu Feng,Jie Ding,Wei Zhang,Chenxing Hu,Qingxiang Zhang,Chen Zhang,Cuiqing Li 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.7
This study reports reactive adsorptive dechlorination of hydrocarbon oil over TiO2-based metal oxides atthe temperatures of 20-150 oC. TiO2 and a series of TiO2-CeO2 were prepared by precipitation method and characterizedby N2 adsorption, XRD, FT-IR, pyridine-IR, NH3-TPD and CO2-TPD. The characterization results showed thatboth the acidity and basicity of the adsorbent had a significant impact on its dechlorination capacity. TiO2-U precipitatedby urea exhibited higher dechlorination capacity than TiO2-A precipitated by ammonia due to the higher surfacearea, more acid and base amounts of the former. Among various Ti(1x)CexO2 (x=0.1, 0.3, 0.5, 0.7, 0.9, 1) oxides,Ti0.7Ce0.3O2 and Ti0.3Ce0.7O2 bimetallic oxides showed higher dechlorination capacity than TiO2-U, and the chlorineremoval over Ti0.7Ce0.3O2 reached 82.8% after adsorption at 150 oC for 3 h. Mixing 5 wt% of alkali earth metal oxideinto Ti0.7Ce0.3O2 mechanically enhanced its dechlorination capacity, and the chlorine removal over Ti0.7Ce0.3O2-BaOreached as high as 92.1%. The chlorine removal increased with increasing the adsorption temperature. Ion chromatographyand GC-MS analysis revealed that organochlorine compound was converted into Cl and its corresponding alcoholover the adsorbent at 150 oC. Finally, the mechanism of reactive adsorption dechlorination was proposed.
Hui Wu,Ting Xu,Xiao Wang,Yong-Bo Yu,Zhong-Yuan Fan,Dan-Xia Li,Lei Luo,Xue-Cheng Yang,Wei Jiao,Hai-Tao Niu 대한남성과학회 2020 The World Journal of Men's Health Vol.38 No.2
Purpose: To compare the diagnostic efficiency of 68Gallium labelled prostate-specific membrane antigen positron emission tomography (68Ga-PSMA PET) and magnetic resonance imaging (MRI) for staging the lymph node metastases (LNMs) in the prostate cancer. Materials and Methods: A broad search of scientific databases including PubMed, EMBASE, Web of Science, Cochrane Database, and Chinese Biomedicine Literature Database (updated prior to November 1st, 2018) was conducted systematically by two reviewers. In this paper, we evaluated the methodological quality of each included article independently and performed a systematic review and meta-analysis to reveal the summary of the diagnostic performance of 68Ga-PSMA PET and MRI in properly identifying LNMs of intermediate- and/or high-risk prostate cancer.Results: Thirteen eligible articles comprising 1,597 patients were included. For LNMs detection, the pooled sensitivity and specificity of 68Ga-PSMA PET were 0.65 (95% confidence interval [CI]: 0.49–0.79) and 0.94 (95% CI: 0.88–0.97), respectively, while the corresponding values of MRI were 0.41 (95% CI: 0.26–0.57) and 0.92 (95% CI: 0.86–0.95). The area under the symmetric receiver-operating characteristic (SROC) curve for 68Ga-PSMA PET and MRI were 0.92 and 0.83, respectively. Conclusions: In intermediate- or high-risk pre-treatment prostate cancer, 68Ga-PSMA PET had a higher sensitivity and a slightly different specificity in probing the LNMs when comparing with MRI. Moreover, the area under the SROC curve indicated that 68Ga-PSMA PET was a more effective weapon for predicting the LNMs prior to radical surgery.
Thrombospondin-2 Couples Pressure-Promoted Chondrogenesis through NF-κB Signaling
Niu Jing,Feng Fan,Zhang Songbai,Zhu Yue,Song Runfang,Li Junrong,Zhao Liang,Wang Hui,Zhao Ying,Zhang Min 한국조직공학과 재생의학회 2023 조직공학과 재생의학 Vol.20 No.5
BACKGROUND: Our previous studies found that the mechanical stimulation promote chondrogenic differentiation of bone marrow mesenchymal stem cells (BMSCs), along with up-regulation of thrombospondin-2 (TSP-2). The aim of this study was to explore the effect of thrombospondin-2 (TSP-2) on the mechanical pressure-stimulated chondrogenic differentiation of BMSCs and the possible role of NF-jB signaling in the mechano-chemical coupling regulation toward chondrogenesis. METHODS: Rat BMSCs were isolated, cultured and identified. The time-dependent expressions of TSP-2 and Sox9 in BMSCs under a dynamic mechanical pressure of 0–120 kPa at 0.1 Hz for 1 h were tested by qPCR and Western blotting. The role of TSP-2 in chondrogenic differentiation of BMSCs under mechanical pressure was validated by using small interfering RNA. The impact of TSP-2 and mechanical pressure on chondrogenesis were detected and the downstream signaling molecules were explored using Western blotting. RESULTS: Mechanical pressure stimulation of 0–120 kPa for 1 h significantly upregulated the expression of TSP-2 in BMSCs. The expression of the chondrogenesis markers Sox9, Aggrecan, and Col-II were all upregulated under dynamic mechanical pressure or TSP-2 stimulation. Additional exogenous TSP-2 may potentiate the chondrogenic effect of mechanical stimulation. After knock down TSP-2, the upregulation of Sox9, Aggrecan and Col-II under mechanical pressure was inhibited. The NF-jB signaling pathway responded to both dynamic pressure and TSP-2 stimulation, and the cartilage-promoting effect was blocked by an NF-jB signaling inhibitor. CONCLUSION: TSP-2 plays an essential role in the chondrogenic differentiation of BMSCs under mechanical pressure. NF-jB signaling is involved in the mechano-chemical coupling of TSP-2 andmechanical pressure for the chondrogenic differentiation of BMSCs.
Niu, Yu-Ming,Shen, Ming,Li, Hui,Ni, Xiao-Bing,Zhou, Juan,Zeng, Xian-Tao,Leng, Wei-Dong,Wu, Ming-Yue Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8
Objective: Findings for associations between the methylenetetrahydrofolate reductase (MTHFR) A1298C gene polymorphism and head and neck cancer risk have been conflicting. We therefore performed a meta-analysis to derive a more precise relationship. Methods: Ten published case-control studies were collected and odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the association between MTHFR A1298C polymorphism and head and neck cancer risk. Sensitivity analysis and publication bias assessment also were performed to guarantee the statistical power. Results: Overall, no significant association between MTHFR A1298C polymorphism and head and neck cancer risk was found in this meta-analysis (C vs. A: OR=1.04, 95%CI=0.87-1.25, P=0.668, Pheterogeneity<0.001; CC vs. AA: OR=1.07, 95%CI=0.70-1.65, P=0.748, $P_{heterogeneity}<0.001$; AC vs. AA: OR=1.06, 95%CI=0.88-1.27, P=0.565, $P_{heterogeneity}<0.001$; CC+AC vs. AA: OR=1.06, 95%CI=0.86-1.30, P=0.571, $P_{heterogeneity}<0.001$; CC vs. AA+AC: OR=1.02, 95%CI=0.69-1.52, P=0.910, $P_{heterogeneity}<0.001$). Similar results were also been found in succeeding analysis of HWE and stratified analysis of ethnicity. Conclusion: In conclusion, our meta-analysis demonstrates that MTHFR A1298C polymorphism may not be a risk factor for developing head and neck cancer.
( Xianli Niu ),( Shirong Nong ),( Junyuan Gong ),( Xin Zhang ),( Hui Tang ),( Tianhong Zhou ),( Wei Li ) 한국미생물생명공학회(구 한국산업미생물학회) 2021 Journal of microbiology and biotechnology Vol.31 No.1
Hepatitis B virus (HBV) genome P-encoded protein HBV DNA polymerase (Pol) has long been known as a reverse transcriptase during HBV replication. In this study, we investigated the impact of HBV Pol on host cellular processes, mainly apoptosis, and the underlying mechanisms. We showed a marked reduction in apoptotic rates in the HBV Pol-expressed HepG2 cells compared to controls. Moreover, a series of assays, i.e., yeast two-hybrid, GST pull-down, co-immunoprecipitation, and confocal laser scanning microscopy, identified the host factor eEF1A2 to be associated with HBV Pol. Furthermore, knockdown of eEF1A2 gene by siRNA abrogated the HBV Pol-mediated anti-apoptotic effect with apoptosis induced by endoplasmatic reticulum (ER) stress-inducer thapsigargin (TG), thus suggesting that the host factor eEF1A2 is essential for HBV Pol’s anti-apoptosis properties. Our findings have revealed a novel role for HBV Pol in its modulation of apoptosis through integrating with eEF1A2.
Xing-hui Zhang,Ke-tai Wang,Teng Niu,Shan-shan Li 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.5
The cycloaddition reactions of the N-heterocyclic carbene boryl azide with methyl acrylate, butenone, and hexafluoropropene have been investigated theoretically. Solvent effects on these reactions have been explored by calculation that included a polarizable continuum model (PCM) for the solvent (C6H6). The title reaction could produce 4- and 5-substituted 1,2,3-triazolines, respectively. The reaction systems have the higher chemical reactivity with the low barriers and could be favored. Yet the smaller differences have been found to occur in energetics, and the cycloaddition reactions occur for s-trans conformations over s-cis conformations. The calculations indicated that the cycloaddition reaction of the alkenes have certain regioselectivity.
A Fast Anti-jamming Decision Method Based on the Rule-Reduced Genetic Algorithm
( Jin Hui ),( Song Xiaoqin ),( Wang Miao ),( Niu Yingtao ),( Li Ke ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.9
To cope with the complex electromagnetic environment of wireless communication systems, anti-jamming decision methods are necessary to keep the reliability of communication. Basing on the rule-reduced genetic algorithm (RRGA), an anti-jamming decision method is proposed in this paper to adapt to the fast channel variations. Firstly, the reduced decision rules are obtained according to the rough set (RS) theory. Secondly, the randomly generated initial population of the genetic algorithm (GA) is screened and the individuals are preserved in accordance with the reduced decision rules. Finally, the initial population after screening is utilized in the genetic algorithm to optimize the communication parameters. In order to remove the dependency on the weights, this paper deploys an anti-jamming decision objective function, which aims at maximizing the normalized transmission rate under the constraints of minimizing the normalized transmitting power with the pre-defined bit error rate (BER). Simulations are carried out to verify the performance of both the traditional genetic algorithm and the adaptive genetic algorithm. Simulation results show that the convergence rates of the two algorithms increase significantly thanks to the initial population determined by the reduced-rules, without losing the accuracy of the decision-making. Meanwhile, the weight-independent objective function makes the algorithm more practical than the traditional methods.