중국 연변 조선족자치주 성인과 한국 구리지역 성인의 식생활 양식 비교

이선희,백희영,김정순,문용,정효지 한국식생활문화학회 2001 韓國食生活文化學會誌 Vol.16 No.4

This study was conducted to investigate dietary patterns and assimilation of dietary culture of Korean descendants in Yanbian, China compared to Korean. A dietary survey was conducted using one 24-hour recall method from 730 adults over 30 years of age in Yanbian, China and 695 adults over 25 years of age in Kuri, Korea. The average number of food items consumed per day was 14 in Yanbian and 20 in Kuri and there was a significant difference between the two regions(p<0.001). The foods consumed most frequently were rice, salt, the M.S.G. in Yanbian and rice, green onion and garlic in Kuri. The foods consumed most by amount were rice, cucumber, Soju in Yanbian and rice, Kimchi and grape in Kuri. The average number of dishes consumed per day was 6.4 in Yanbian, 9.4 in Kuri and the difference between the two regions was significant(p<0.001). Total number of dishes appeared in the survey was 253 in Yanbian and 494 in Kuri. The dishes consumed most frequently were cooked-rice, beverages, Kimchi, stir-fried eggplant in Yanbian and cooked-rice, Kimchi, coffee, soybean paste stew, in Kuri. The dish groups appeared most frequently were rice, stir-fried foods, vegetables and Kimchi in Yanbian and rice, Kimchi, beverages and fruits in Kuri. Male subjects in Yanbian Consumed alcohol frequently while adults in Kuri consumed coffee more frequently than Yanbian. The major meal patterns were rice+side dish, rice+soup, rice+side dish+Kimchi in Yanbian and rice+soup+side dish+Kimchi, rice+side dish+Kimchi, rice+soup+Kimchi in Kuri. Stir-fried foods, which were consumed 46.6% of all the meals, were dominant side dish in Yanbian, but stir-fried food, seasoned vegetables and grilled food appeared aver 10% in Kuri. There results show that variety of diet of Korean-Chinese in Yanbian was lower than Kuri. Korean-Chinese tend to keep traditional Korean dietary patterns of consuming rice as staple but were adapted to Chinese dietary patterns of consuming stir-fried side dishes. Efforts should be directed toward preserving Korean traditional patterns of dietary culture among Korean-Chinese population.

Design and applications of fluorescent detectors for peroxynitrite

Wang, Shan,Chen, Liyan,Jangili, Paramesh,Sharma, Amit,Li, Wei,Hou, Ji-Ting,Qin, Caiqin,Yoon, Juyoung,Kim, Jong Seung Elsevier 2018 Coordination chemistry reviews Vol.374 No.-

<P><B>Abstract</B></P> <P>Peroxynitrite (ONOO<SUP>−</SUP>) is one of the endogenous reactive oxygen species (ROS), which causes damage to a wide array of molecular components in the cells, including DNA and proteins, owing to its high oxidizing as well as nitrating properties. However, the precise pathogenic roles played by this substance in biological systems have not yet been elucidated completely owing to its short lifetime, high reactivity, low concentration and elusive nature in the <I>in vivo</I> applications. Thus, the development of more sensitive and selective techniques for detecting ONOO<SUP>−</SUP>, with high biocompatibilities, sensitivities, and site-specificities, is a significant goal. This review summarizes the recent advances that have been made in developing fluorescent sensors for ONOO<SUP>−</SUP> and their biological applications in diverse living systems.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The general significance of ONOO<SUP>−</SUP> detection. </LI> <LI> The design strategies of functional ONOO<SUP>−</SUP> probes. </LI> <LI> The diverse platforms to design ONOO<SUP>−</SUP> probes, including small molecules, proteins and nanocarriers. </LI> <LI> The diverse biological applications of fluorescent ONOO<SUP>−</SUP> probes. </LI> <LI> Perspectives and potential future directions. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>In this review, the development of fluorescent probes for peroxynitrite detection since 2013 is described. The chemical sensor’s designs has been classified by their reaction based sensing patterns.</P> <P>[DISPLAY OMISSION]</P>

Release dynamics of As, Co, and Mo in a biochar treated soil under pre-definite redox conditions

El-Naggar, Ali,Shaheen, Sabry M.,Hseu, Zeng-Yei,Wang, Shan-Li,Ok, Yong Sik,Rinklebe, Jö,rg Elsevier 2019 The Science of the total environment Vol.657 No.-

<P><B>Abstract</B></P> <P>This study assessed the impact of pre-definite redox potential (E<SUB>H</SUB>) on the release dynamics and distribution of As, Co, and Mo between the dissolved and colloidal phases as well as their potential mobility and phytoavailability in the sediment phase of a mining soil treated with rice hull biochar (BC). The experiment was conducted from controlled moderately-reducing to oxidizing conditions using an automated biogeochemical microcosm system. Arsenic and Mo were more abundant in the dissolved phase due to their predominant in potential mobile fractions, while Co was more abundant in the colloidal phase due to its association with Fe-(hydr)oxides. Biochar increased the dissolved and colloidal concentrations of As, the dissolved concentration of Co, and the colloidal concentration of Mo under oxidizing condition. On the other hand, the application of BC decreased the dissolved concentration of Mo and the colloidal concentration of Co in the first redox cycle under reducing-acidic condition, due to lower pH values, and chemistry of sulfide-sulfate and Fe/Mn oxides. The phytoavailability of As and Co were higher than their potential mobility in the sediment phase, while the same trend was not discerned for Mo. The potential mobility and phytoavailability of As and Co were high under oxic-acidic conditions. The potential mobility and phytoavailability of Mo might be increased under oxic condition due to the dissolution of Fe and Mn oxides under lower pH conditions, especially in the BC treated soil. Application of such rice hull BC to soil might stimulate the release of As, Co, and Mo under flooding conditions, which might increase the environmental and health risks in such wetland ecosystems.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The E<SUB>H</SUB> showed a converse relation with pH in biochar treated and non-treated soils. </LI> <LI> Arsenic and Mo were abundant in the dissolved phase, but Co in the colloidal phase. </LI> <LI> Biochar increased the dissolved As and Co under oxidizing conditions. </LI> <LI> Biochar decreased the dissolved Mo under acidic conditions in the first redox cycle. </LI> <LI> Potential mobility and phytoavailability were higher under low pH and high E<SUB>H</SUB>. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Systematic Functional Annotation of Somatic Mutations in Cancer

Ng, Patrick Kwok-Shing,Li, Jun,Jeong, Kang Jin,Shao, Shan,Chen, Hu,Tsang, Yiu Huen,Sengupta, Sohini,Wang, Zixing,Bhavana, Venkata Hemanjani,Tran, Richard,Soewito, Stephanie,Minussi, Darlan Conterno,Mo Cell Press 2018 CANCER CELL Vol. No.

<P><B>Summary</B></P> <P>The functional impact of the vast majority of cancer somatic mutations remains unknown, representing a critical knowledge gap for implementing precision oncology. Here, we report the development of a moderate-throughput functional genomic platform consisting of efficient mutant generation, sensitive viability assays using two growth factor-dependent cell models, and functional proteomic profiling of signaling effects for select aberrations. We apply the platform to annotate >1,000 genomic aberrations, including gene amplifications, point mutations, indels, and gene fusions, potentially doubling the number of driver mutations characterized in clinically actionable genes. Further, the platform is sufficiently sensitive to identify weak drivers. Our data are accessible through a user-friendly, public data portal. Our study will facilitate biomarker discovery, prediction algorithm improvement, and drug development.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Developed a versatile functional genomic platform for somatic mutation annotation </LI> <LI> Annotated >1,000 genomic aberrations, doubling the number of known driver mutations </LI> <LI> Assessed performance of existing algorithms for mutation functional predictions </LI> <LI> Built a user-friendly, open-access data portal for community-based investigation </LI> </UL> </P> <P><B>Graphical Abstract</B></P> <P>[DISPLAY OMISSION]</P>

Highly efficient synthesis of novel methyl 13²-methylene mesopyropheophorbide <i>a</i> and its stereoselective Michael addition reaction

Li, Jiazhu,Liu, Yang,Xu, Xi-Sen,Li, Yan-Long,Zhang, Shan-Guo,Yoon, Il,Shim, Young Key,Wang, Jin-Jun,Yin, Jun-Gang The Royal Society of Chemistry 2015 Organic & Biomolecular Chemistry Vol.13 No.7

<P>Treatment of methyl mesopyropheophorbide <I>a</I> with formaldehyde under basic conditions gave a novel 13<SUP>2</SUP>-methylene derivative in 85% yield; under acidic conditions, the corresponding 20-hydroxymethyl derivative was obtained in 65% yield. The high reactivity of the enone structural motif existed in the former product provides a unique way to construct some novel chlorophyll <I>a</I> derivatives for various applications. Stereoselective Michael reaction of this compound is studied and discussed.</P> <P>Graphic Abstract</P><P>pH-Dependent regioselective condensation of methyl mesopyropheophorbide <I>a</I> with HCHO is studied and stereoselective Michael reaction of the 13<SUP>2</SUP>-methylene product is also discussed. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c4ob02491e'> </P>

Flowering and flowering genes: from model plants to orchids

Shan-Li Wang,Hye Ryun An,Chii-Gong Tong,Seonghoe Jang 한국원예학회 2021 Horticulture, Environment, and Biotechnology Vol.62 No.2

Floral transition in model plants including Arabidopsis and rice has been studied extensively through molecular geneticapproaches. Many genetic factors in diff erent fl owering pathways, which depend mainly on photoperiod, vernalization,autonomous and ambient temperature are regulated coordinately to control fl oral induction. However, for the ornamentalplants orchids, the molecular mechanisms underlying the fl oral transition are still unclear. Recently, genes with potentialfl owering-related functions have been identifi ed in diff erent orchid species and their functional roles have also been characterized/examined using homologous or heterologous systems. In this review, we summarize the molecular networks offl owering genes and their regulation as revealed in model plants such as Arabidopsis and rice, and also describe the recentdiscoveries/studies on fl owering genes in several commercially representative orchid species providing a perspective onorchid fl owering research. In addition, our recent results through transgenic approaches with ectopic expression of Hd3a , arice fl origen gene for the induction of precocious fl owering in Phalaenopsis orchids are also discussed.

Luminescent characteristics of Sr2ZnSi2O7 : Eu3+ phosphor for ultraviolet light emitting diodes

Shan-shan Yao,Li-hong Xue,You-wei Yan,Yuan-yuan Li,Mi-fang Yan 한양대학교 세라믹연구소 2010 Journal of Ceramic Processing Research Vol.11 No.6

Red-emitting phosphors Sr2-xZnSi2O7 : Eux 3+ was prepared by a combustion-assisted synthesis method and an efficient red emission under near-ultraviolet (UV) was observed. The luminescence, crystallinity, and particle sizes were investigated using luminescence spectrometry, X-ray diffractometry, and field scanning electron microscopy. The emission spectrum shows that the most intense peak is located at 614 nm, which corresponds to the 5D0→ 7F2 transition of Eu3+. The phosphor has two main excitation peaks located at 394 and 465 nm, which match the emission of UV and blue light-emitting diodes, respectively.

A biodegradable drug‐controlled delivery system based on mesoporous manganese dioxide and poly(dopamine)

Li Miaomiao,Cai Wenrong,Jiang Lihua,Li Junyao,Li Shan,Tang Tongtong,Kong Yong 대한화학회 2023 Bulletin of the Korean Chemical Society Vol.44 No.12

Mesoporous manganese dioxide (mMnO 2 ) was first synthesized for the loading of methotrexate (MTX), and then dopamine was in situ polymerized on the surface of the MTX‐loaded mMnO 2 (mMnO 2 ‐MTX) in an alkaline solution to encapsulate the drug in the mesopores of mMnO 2 . Both low pH and glutathione (GSH) can result in the degradation of mMnO 2 and poly(dopamine) (PDA), and thus the delivery of MTX from the mMnO 2 ‐MTX‐PDA can be triggered by low pH and GSH. Near‐infrared (NIR) light‐responsive delivery of MTX can be achieved owing to the outstanding photothermal conversion capability of PDA; on the other hand, the mMnO 2 ‐MTX‐PDA can be utilized for photothermal therapy under the irradiation of NIR light due to the elevated temperature. The results of cytotoxicity test demonstrate that the pH, GSH, and NIR light tri‐responsive drug‐controlled delivery system has excellent biocompatibility, while exhibits pronounced growth inhibition against murine breast tumor cell line 4T1. Mesoporous manganese dioxide (mMnO2) was first synthesized for the loading of methotrexate (MTX), and then dopamine was in situ polymerized on the surface of the MTX-loaded mMnO2 (mMnO2-MTX) in an alkaline solution to encapsulate the drug in the mesopores of mMnO2. Both low pH and glutathione (GSH) can result in the degradation of mMnO2 and poly(dopamine) (PDA), and thus the delivery of MTX from the mMnO2-MTX-PDA can be triggered by low pH and GSH. Near-infrared (NIR) light-responsive delivery of MTX can be achieved owing to the outstanding photothermal conversion capability of PDA; on the other hand, the mMnO2-MTX-PDA can be utilized for photothermal therapy under the irradiation of NIR light due to the elevated temperature. The results of cytotoxicity test demonstrate that the pH, GSH, and NIR light triresponsive drug-controlled delivery system has excellent biocompatibility, while exhibits pronounced growth inhibition against murine breast tumor cell line 4T1.

Concentration quenching of Eu^2+ in Ba_2Mg(BO_3)_2: Eu^2+ phosphor

Shan-shan Yao,Li-hong Xue,You-wei Yan 한국물리학회 2011 Current Applied Physics Vol.11 No.3

The red emitting phosphor Ba_2Mg(BO_3)_2: Eu^2+ is prepared by the combustion-assisted method. An efficient red emission under conditions ranging from ultraviolet to visible light is observed. The emission spectrum shows a single intensive band centered at 610 nm, which correspond to the 4f^65d^1 → 4f^7transition of Eu^2+. The critical quenching concentration of Eu^2+ in Ba_2Mg(BO_3)_2: Eu^2+ phosphor is about 0.05 mol. The corresponding concentration quenching mechanism is verified to be a dipole―dipole interaction. The value of the critical transfer distance is calculated as 17.32 Å, which is in good agreement with the value (18 Å) derived from the experimental data.

Enhancing the Robustness and Efficiency of Scale-free Network with Limited Link Addition

( Li Li ),( Qing-shan Jia ),( Xiaohong Guan ),( Hengtao Wang ) 한국인터넷정보학회 2012 KSII Transactions on Internet and Information Syst Vol.6 No.5

The robustness of a network is usually measured by error tolerance and attack vulnerability. Significant research effort has been devoted to determining the network design with optimal robustness. However, little attention has been paid to the problem of how to improve the robustness of existing networks. In this paper, we investigate how to optimize attack tolerance and communication efficiency of an existing network under the limited link addition. A survival fitness metric is defined to measure both the attack tolerance and the communication efficiency of the network. We show that network topology reconfiguration optimization with limited link addition (NTRLA) problem is NP-hard. Two approximate solution methods are developed. First, we present a degree-fitness parameter to guide degree-based link addition method. Second, a preferential configuration node-protecting cycle (PCNC) method is developed to do trade-off between network robustness and efficiency. The performance of PCNC method is demonstrated by numerical experiments.