http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
식도정맥류출혈에 대한 내시경적 경화요법의 시술방법에 따른 지혈효과의 비교연구
이헌영,이기천,정현용,김영건 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2
Endoscopic Injection Sclerotherapy(EIS) is currently the primary treatment of choice for the majority of patients who present esophageal vsarix bleeding. But, in EIS, unanswered methodologic problem and controversies remain. We assigned 99 patients with esophageal varix bleeding seen at Chungnam National University Hospital from May. 1989 to Dec. 1991. Single injection at one varix column was made in 73 patients (Mono-puncture group) and multiple injections were made in 26 patients (Multi-punctures group). The results are follows 1) Mean age was 48.01±11.4 years and male to female ratio was 7:1, but there was no difference between 2 groups. 2) Most frequent etiology of bleeding varices were alcoholic liver cirrhosis(43 %) and hepatitis B virus associated liver cirrhosis(31%), and the most patients had a advanced liver disease, such as Child's classification B(46%) and C(29%), but there was no difference between 2 groups. 3) In variceal form, rates of Fl, F2 & F3 were 2%, 27%, & 67%, and red color sign was seen in 80% of patients, but there was no difference between 2 groups. 4) Total number of treatment were 3.1± 2.1 in mono-puncture group and 4.1± 3.0 in multi-puncture group, and total volumes of sclerosant were 21.3± 17.Oml, 30.3± 19.4m1. Mean volumes per treatment session was 6.9± 4.5ml, 7.4± 5.9ml, and mean volume per one puncture site were 1.6± 1.0 ml and 1.1± 0.9ml. There were significantly difference between 2 groups in total volume of sclerosant and mean volume per one puncture site. 5) Before and after EIS, the changes of hematologic finding were not significant, and transfusion requirments were decreased, in both groups. 6) Complications of EIS were chest and epigastric pain(82%), fever(31%), pleural effusion(8%), sclerotherapy failure(9%) and rebleeding during admission(15%), but there was no difference between 2 groups. These findings suggest that differences of clinical effects and complications were not significant between 2 groups.
B형 만성 활동성 간염 환자에서 Prednisolone 단기이탈 및 Alpha Interferon 병합요법의 효과
이종선,김병호,성자원,허승식,이기천,정현용,이헌영,김영건 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2
To evaluate the safety and efficacy of Pd withdrawal followed by recombinant alpha- Interferon 2b therapy. Nine patients were given a single daily subcutaneous injection of ^α-Interferon at a dose of 3 x 10 exp(6) units/day for first weeks and thrice weekly for next 15 weeks (maintenance) after pd tappered over 6 weeks. To evaluate the efficacy of therapy, we measured serum aminotransferase activities monthly during and after therapy, and also measured serm HBsAg, HBeAg and DNA probe before and after therapy. To evaluate the safety of therapy, all patients checked peripheral blood WBC, Hemoglobin, Platelet, BUN and Creatinine. The results were as follows : 1. In control group, the normalization of s-AST & ALT level, negative seroconversion of DNA probe & HBeAg were observed in 1/12(8%) & 7/10(17%), 0/10(0%) & 0/12(0%) at 6 months later, and maintained response in 1/11(9%) & 1/11(9%), 2/9(22%) & 2/11(18%) until 1 years later. 2. In treatment group, Serum AST and ALT returned to normal in 8/9 & 8/9 cases (89%) after 1 montns Tx. (mean serum AST : 33±8, ALT : 34±12 IU/ml) and maintained to normal response in 5/9(56%) & 6/9 cases(67%)after 6 months Tx. (mean s-AST : 55±43, ALT : 66±84 IU/ml), 3/9(33%) & 4/9 cases(44%) after 1 years Tx. It was statistically significant reponse except s-AST of after 1 years Tx. 3. In treatment group, s- HBeAg returned to normal in 3/9 cases(33%) after 1 months Tx., and maintained to normal response in 1/7 & 1/4 cases among follow up patients in after 6 & 12 months Tx. Serm DNA probe level were observed significantly negative seroconversion in 8/9 cases(89%) after 1 months Tx. (p<0.003), and maintained to negative response in 2/6 & 1/3 cases after 6 & 12 months Tx. 4. Serum AST, ALT, HBeAg and DNA probe were not significantly correlated with therapeutic response in relation to histologic diagnosis. 5. Fever and myalgia were noted in 9(100%) & 6(67%) cases. Headache, mild hair loss, anorexia, nausea, facial flushing & diarrhea were noted in few cases. Peripheral WBC(3cases) & platelet counts(3cases) were decreased transiently. This study shows that Pd withdrawal followed by recombinant alpha Interferon 2b therapy may be safe and effective in decrease the level of s-DNA probe, transaminase activity, loss of HBeAg and less adverse effect of clinical and hematologic examinations in patients with CAH type B. But it was necessary for study with large number of patients, more prolonged follow up duration and more strict control study.
김영건,육은주,김성걸,임의혁,성자원,김병호,허승식,이기천,정현용,이헌영 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2
A clinical analysis was performed of 3055 pateints with peptic ulcer who were diagnosed with gastroduodenoscopy, in Hospital of Chungnam National University College of Medicine from July 1988 to May 1993. 1) During the period 1988-1993, The proportion of gastric ulcer among peptic ulcer decreased from 47.8% to 42.8%, but that of duodenal ulcer increased from 36.8% to 39.6%. 2) Of the 3055 cases, the number of patients with esophageal ulcer was 98(3.2%), with gastric ulcer 1407(41.6%), with. duodenal ulcer 1104(36.1%), with channel ulcer 149(4.9%), and with combind ulcer 297(9.7%). 3) We observed a peak incidence of peptic ulcer in the 50-69age group, gastric ulcer in the 5069age, duodenal ulcer in the 40-59age group. The ratio of male to female was 3.6 : 1 in peptic ulcer, 4.4 : 1 in gastric ulcer, 3.0 : 1 in duodenal ulcer. 4) The common site was angle in gastric ulcer, and bulb in duodenal ulcer. 5) The active stage was 39.4% of gastric ulcer, and 37.4% of duodenal ulcer, the healing stage was 34.2% of gastric ulcer, and 17.9% of duodenal ulcer, and the scar stage of gastric ulcer was 26.4%, and duodenal ulcer was 44.7%. 6) The size of ulcer was less than 1Cm in 66.7% of gastric ulcer, and in 75.5% of duodenal ulcer, the size of ulcer was greater than 2Cm in 13.2% of gastric ulcer, and in 6.5% of duodenal ulcer. 7) The frequency of multiple ulcer was 29.9% in gastric ulcer, and 16.5% in duodenal ulcer.
Cheon, Sun-Ha,Lee, Yu-Na,Kang, Sung-Il,Kye, Soo-Jeong,Lee, Eun-Kyoung,Heo, Gyeong-Beom,Lee, Myoung-Heon,Kim, Jeong-Won,Lee, Kwang-Nyeong,Son, Han-Mo,Lee, Youn-Jeong Elsevier 2018 INFECTION GENETICS AND EVOLUTION Vol.66 No.-
<P><B>Abstract</B></P> <P>Avian influenza viruses (AIVs) are genetically separated by geographical barriers, resulting in the independent evolution of North American and Eurasian lineages. In the present study, to determine whether AIVs possessing the North American-origin nonstructural (NS) gene were previously introduced into South Korea, we performed a genetic analysis of AIVs isolated from fecal samples of migratory birds. We detected seven viruses possessing the North American-origin NS allele B among 413 AIV-positive samples obtained during AI surveillance between 2012 and 2017. We found evidence for the intercontinental transmission of at least three genetically distinct clusters of the B allele of the North American-origin NS gene into Eurasia at a low frequency. The host species of three viruses were identified as the greater white-fronted goose (<I>Anser albifrons</I>) using a DNA barcoding technique. Moreover, we used GPS-CDMA-based telemetry to determine the migration route of the greater white-fronted goose between the Far East of Russia and South Korea and found that this species may play an important role as an intermediate vector in the intercontinental transmission of AIVs. To improve our understanding of the role of wild birds in the ecology of AIVs, advanced AIV surveillance is required in the Far East of Russia as well as in Alaska region of Beringia accompanied by host identification and wild bird tracking.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Seven AIVs carrying North American-origin NS allele B were identified in Korea. </LI> <LI> Three genetically distinct clusters of NS allele B were detected. </LI> <LI> Greater white-fronted goose was implicated in the intercontinental transfer of AIV. </LI> </UL> </P>
Heon Cheon Jeong,Jung A Kim,Hyun Hwak Im,Hyung Uk Jeong,Mee Yeon Hong,Jong Eun Lee,Yeon Soo Han,Iksoo Kim 한국응용곤충학회 2008 한국응용곤충학회 학술대회논문집 Vol.2008 No.10
We analyzed a portion of mitochondrial COI gene sequences (658 bp) to investigate the genetic diversity and geographic variation of the swallowtail butterfly, Papilioxuthus L., and the cabbage butterfly, Pieris rapae (Lepidoptera: Papilionidae). P. xuthus showed a moderate level of sequence divergence (0.91% at maximum) in 15 haplotypes, whereas P. rapae showed a moderate to high level of sequence divergence (1.67% at maximum) in 30 haplotypes, compared with other relevant studies. Analyses of population genetic structure showed that most populations are not genetically differentiated in both species. The distribution pattern of both species appears to be consistent with category IV of the phylogeographic pattern sensu Avise (Avise et al. 1987): a phylogenetic continuity, an absence of regional isolation of mtDNA clones, and extensive distribution of close clones. The observed pattern of genetic diversity and geographic variation of the two butterfly species seems to reflect the abundant habitats, abundant host plants, and flying abilities in connection with the lack of historical biogeographic barriers.
A new record of Lyssa zampa (Butler) from Korea
Jeong, Heon-Cheon,Kim, Min-Jee,Kim, Iksoo,Choi, Sei-Woong The National Institute of Biological Resources 2016 Journal of species research Vol.5 No.2
An Uraniidae moth, Lyssa zampa (Butler, 1869) is newly discovered from southern Korea. One male specimen was collected at a valley of south aspect of Mt. Hallasan, Jejudo in July, 2014. This species is briefly described and illustrated here. DNA barcoding sequence (Genbank KU160388) for the species was provided for species identification.