노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

Lysophosphatidic acid increases mesangial cell proliferation in models of diabetic nephropathy via Rac1/MAPK/KLF5 signaling

Kim, Donghee,Li, Hui Ying,Lee, Jong Han,Oh, Yoon Sin,Jun, Hee-Sook Nature Publishing Group UK 2019 Experimental and molecular medicine Vol.51 No.2

<▼1><P>Mesangial cell proliferation has been identified as a major factor contributing to glomerulosclerosis, which is a typical symptom of diabetic nephropathy (DN). Lysophosphatidic acid (LPA) levels are increased in the glomerulus of the kidney in diabetic mice. LPA is a critical regulator that induces mesangial cell proliferation; however, its effect and molecular mechanisms remain unknown. The proportion of α-SMA<SUP>+</SUP>/PCNA<SUP>+</SUP> cells was increased in the kidney cortex of <I>db/db</I> mice compared with control mice. Treatment with LPA concomitantly increased the proliferation of mouse mesangial cells (SV40 MES13) and the expression of cyclin D1 and CDK4. On the other hand, the expression of p27<SUP>Kip1</SUP> was decreased. The expression of Krüppel-like factor 5 (KLF5) was upregulated in the kidney cortex of <I>db/db</I> mice and LPA-treated SV40 MES13 cells. RNAi-mediated silencing of KLF5 reversed these effects and inhibited the proliferation of LPA-treated cells. Mitogen-activated protein kinases (MAPKs) were activated, and the expression of early growth response 1 (Egr1) was subsequently increased in LPA-treated SV40 MES13 cells and the kidney cortex of <I>db/db</I> mice. Moreover, LPA significantly increased the activity of the Ras-related C3 botulinum toxin substrate (Rac1) GTPase in SV40 MES13 cells, and the dominant-negative form of Rac1 partially inhibited the phosphorylation of p38 and upregulation of Egr1 and KLF5 induced by LPA. LPA-induced hyperproliferation was attenuated by the inhibition of Rac1 activity. Based on these results, the Rac1/MAPK/KLF5 signaling pathway was one of the mechanisms by which LPA induced mesangial cell proliferation in DN models.</P></▼1><▼2><P><B>Kidney disease: Mechanisms of diabetes-related damage</B></P><P>A potent molecular mediator of diabetic kidney disease induces its pathogenic effects via proteins that could be targeted with future drug therapies. Yoon Sin Oh
from Eulji University in Seongnam-si and Hee-Sook Jun from Gachon University in Incheon, both in South Korea, and colleagues treated certain cells found in the kidney’s glomerulus, the organ’s filtering unit, with a signaling molecule called lysophosphatidic acid (LPA) that is elevated in the blood of diabetic mice. They showed that LPA stimulated cellular proliferation and boosted the expression of proteins involved in regulating the cell cycle and a multipurpose signaling pathway. They then inhibited the activity of these proteins to prevent the kidney cells’ hyperproliferation, both in cell culture and in diabetic mice. The results highlight the potential of blocking mediators of LPA signaling to treat kidney-related complications of diabetes.</P></▼2>

뇌졸중 환자 가족의 돌봄의 경험 : 현상학적 연구

윤숙희 인제대학교 1995 仁濟論叢 Vol.11 No.2

The concept of the family burden for helping patients in the hospital as well as in the home setting has been raised as a nursing issue recently Those who survive stroke are discharged to home disabled and the responsibility for providing adequate care to the patient has fallen primarily on family members. Therefore this study using phenomenologic approach was carried out to explore and explain the experiences of family caregivers of stroke. The informants of the study were 5 family caregivers caring for the patients with stroke at hospitals or their homes. The study was conducted from Novembers 1995 through January, 1996. Data were collected through in-depth interviews, telephone interviews and narrative data. Data collection and analysis were conducted concurrently. Analysis method of data was Giorgic method. According to the results, caregiving has been associated with emotional crisis, physical discomfort, guilty feeling, anxiety, feeling of social isolation and depression. This study offers better understanding on the caregiving experiences and may facilitate more appropriate interventive strategies.

임상간호사의 직무스트레스와 우울 : 한국인 직무스트레스 측정도구를 이용하여

윤숙희 대한간호학회 간호행정학회 2009 간호행정학회지 Vol.15 No.3

Purpose: The purpose of this study was to examine the level of occupational stress and depression in clinical nurses and to investigate the effects of subscales of occupational stress on depression. Method: A sample consisted of 202 nurses from 6 hospitals located in Busan and GyeongNam province. The data were collected from November 2008 to march 2009. A self-administered questionnaire was used to assess socio-demographics, job characteristics, depression measured by Korean CES-D, and occupational stress assessed by KOSS. Result: The total score of occupational stress in clinical nurses was within bottom 25%, but the scores of 'Difficult physical environment', 'High job demand', 'Inadequate social support', 'Organizational injustice' were within top 50%. The 8 subscales of occupational stress had significantly effects on clinical nurses' depression after controlling for age, marital status, type of hospital, current position. Conclusion: The administration of employee assistance program for management occupational stress is important for decreasing depression in clinical nurses.

관상동맥 스텐트 내 재협착의 발생에 미치는 임상적 관동맥 조영술적 요인들

윤혁준,김기식,박형섭,이영수,현대우,한성욱,허승호,김윤년,김권배,박남희,원경숙 대한순환기학회 2003 Korean Circulation Journal Vol.33 No.12

노인요양시설 거주노인의 생활만족도

윤숙희 인제대학교 2010 仁濟論叢 Vol.25 No.1

This study aims at providing high quality of nursing care to improve life satisfaction for the elderly in nursing home. A sample consisted of 92 older residence from 6 nursing home located in Busan and GyeongNam province, The data were collected during Aug, 2009, A self-administered questionnaire was used to assess socio-demographics, life satisfaction, The total score of life satisfaction of the elderly in nursing home was 13.75(±5.38). The general characteristics related to life satisfaction were gender, age, spouse, monthly allowance, education, health condition, length of stay in nursing home, The development of supportive program for increasing life satisfaction of the elderly is needed in nursing home.

간호사의 직무스트레스와 노인에 대한 지식, 태도 및 케어실천행위

윤숙희 대한간호학회 간호행정학회 2009 간호행정학회지 Vol.15 No.4

Purpose: This study was to examine the relation of nurses' job stress and knowledge, attitude and care behavior for elderly patient in hospitals. Method: One hundred ninety one nurses caring the elderly patients in hospitals in Ilsan, Busan and Gyeongsangnam-do were subjects. The data was collected between Sept. 21 and 31, 2009. Data was analyzed using t-test, ANOVA, Pearson correlation with SPSS/Win 17.0 and the fitness of pathway models with AMOS 5.0. Results: The mean scores of job stress and knowledge were in middle range, and attitude and care behavior were in a little higher range. The fitness of hypothetical model was excellent. Job stress had direct effects on attitude and care behavior, knowledge had direct effect on attitude and attitude had direct effect on care behavior. But the pathways related to job stress and attitude and job stress and care behavior were not significant. In modified model deleted the pathway between job stress and attitude, the pathway related to job stress and behavior also was not significant. Conclusion: Education related to the elderly for nurses to improve care behavior is needed continuously.

고등학생들의 음란물 접촉실태 및 관련요인

윤분희,정문숙,한창현,어윤국 慶山大學校 保健福祉硏究所 2002 保健福祉硏究 Vol.7 No.-

본 연구는 성에 민감한 청소년들의 음란물 접촉 실태를 알아보기 위하여 1998년 11월 30일부터 12월 30일까지 경상남도 J시 소재 고등학교 2학년 학생 732명을 대상으로 설문 조사 분석한 결과는 다음과 같다. 음란물 접촉실태는 대상자가 가장 많이 접촉하는 음란물은 성인용 비디오(76.9%)이었고 성인용 만화(70.1%), 성인용 주간지(55.9%), 음란 컴퓨터 프로그램(51.2%), 포로노 비디오(50.3%), 포로노 잡지(34.4%) 및 포로노 사진집(28.1%) 순이었다. 인문계 학생이 가장 많이 접촉하는 음란물은 성인용 만화이었고, 실업계 학생은 성인용 비디오였으며 남학생이 여학생보다, 실업계 학생이 인문계 학생보다 음란물 접촉 경험이 더 많았다.(p<0.01) 음란물 접촉 시 특성을 보면 대부분 학생이 "중학교"때 처음 접촉했으며 접촉경로응 "친구를 통해서"가 가장 많았고, 접촉이유는 "호기심 때문에"가 가장 많았다. 제반 변수들에 따른 음란물 접촉과의 연관성을 알아본 결과 자위행위, 성 경험, 이성교제, 학생성적, 흡연, 음주는 모든 음란물의 접촉과 상관성이 있는 것으로 나타났다.(p<0.01) 음란물 접촉 유무를 종속변수로 하여 다중 로지스틱 분석을 한 결과는 남자일수록, 자위행위를 할수록, 학교 성적이 낮을수록, 담배를 피울수록, 술을 마실수록, 외향성일수록 음란물을 보는 경험이 더 많았다.(p<0.01) 이상 결과들을 볼 때, 청소년들을 음란물로부터 보호하기 위해서는 성적충동을 올바르게 표출하고 승화할 수 있도록 개개인의 취향에 맞는 운동이나 취미활동을 권장하고 이를 개발할 수 있도록 도와주어야 할 것이며 유해환경에 대한 규제를 강화하여 학생들이 살고 잇는 사회의 성문화 정화에 모두 관심을 가져야겠다. This study was conducted to examine the sex-sensitive adolescents' actual condition of contact with lecherous things from November 11th to December 20th, 1998 with 732 high school sophomores in Chinju, Kyungsangnam-do. And the results are as follows. According to the actual condition of contact with lecherous things the most lecherous thing subject group came into contact was adult videos(76.9%) and adults cartoons(70.1%), adults magazines(55.9%), lecherous computer programs(51.2%), porn videos(50.3%), porn magazines(34.4%) and porn photo collections(28.1%) in highest order. The most lecherous thing academic high school students came into contact was adults cartoons and that of business high school students was adults videos and contact experiences to it of male students and business school students were higher than those of female students and academic school students respectively(p<0.01%). In view of students' characteristics of contact with lecherous things, most students made first contact with them in their middle school years and from their friends curiosity. In the result of study of relevance to the contact with lecherous things due to all sorts of variables, it shows that masturbations, sex experiences, intersexual acquaintances, school records, smoking and drinking are related to the all contacts with lecherous things(p<0.01). In the result of Multiple Logistic Analysis with the presence of contact with lecherous things as subordinate variable, the more they are men, doing masturbations, the person with bad school records, smoking, drinking and extroversive the more they are inclined to contact with lecherous things(p<0.01). To protect adolescents from the access to lecherous things, in view of above results, we have to encourage and help adolescents to enjoy and develop sports or hobbies of their own to express and purify their sexual impulses right. And we also have to concern the purification of sexual culture of the society in which students live by strengthening our regulatory systems for unsound circumstances.

제2형 당뇨병 환자에게 적용한 표준진료지침이 혈당, 당화혈색소, 당뇨지식 및 재원일수에 미치는 효과

김희승,윤건호,유양숙,오정아,송민선,신미옥,김경희,송복례 대한당뇨병학회 2002 임상당뇨병 Vol.3 No.1

연구배경 : 당뇨병 환자의 평균 재원기간을 단축시키고, 제한된 입원기간 내에서 질적인 면과 비용효과성을 고려한 총체적인 건강관리체계의 필요성이 요구됨으로써 생겨난 것이 당뇨병 표준진료지침(Critical Pathway: CP)이다. 현재 개발된 당뇨병 CP를 통한 진료가 환자의 당뇨병에 관한 지식을 개선시키고 이에 따라 장기적으로 당뇨병 환자의 혈당조절이 개선되었다는 과학적인 검증은 당뇨병 CP를 여러 병원에 정착시키기이전에 반드시 선행되어야 할 과제이다. 이에 본 연구는 2000년 3월부터 1년간 강남성모병원에 입원하는 당뇨병 환자를 대상으로 현재 개발된 1주일 CP를 적용한 실험군의 혈당, 당뇨병 관련 지식 및 재원일수가 대조군에 비하여 차이가 있는지를 조사하였다. 방법 : 1주일 CP를 적용한 실험군은 내과병동에 입원한 당뇨병 환자 89명이었고, 대조군은 기타병동에 입원한 당뇨병 환자 22명이었으며 CP를 적용하지 않았다. CP를 적용하기 전인 입원시에 실험군과 대조군의 공복혈당, 식후 2시간혈당, 당화혈색소 및 당뇨관련 지식을 측정하였고, 퇴원 시에 실험군과 대조군에게 공복혈당과 당뇨관련 지식을 재측정하고 재원일수를 파악하였다. 그리고 두 군에게 퇴원 3개월 후의 공복혈당, 식후 2시간 혈당 및 당화혈색소를 조사하였다. 결과 : 1) 실험군의 공복혈당은 입원 시 238.7: 1) 실험군의 공복혈당은 입원 시 238.7mg/dL에서 퇴원 시 139.4mg/dL로 감소하는 경향이었으나 퇴원 3개월 후에는 150.6mg/dL로 약간상승하는 경향을 보였다. 대조군은 입원 시 251.5mg/dL에서 퇴원 시 136.2mg/dL로 감소하는 경향이었으나, 퇴원 3개월 후에는 219.3mg/dL로 현저히 증가하는 경향이었다. 2) 실험군의 입원 시 식후 2시간 혈당은 312.5mg/dL에서 퇴원 3개월 후 248.5mg/dL로 감소하는 경향이었다. 대조군도 입원 시 식후 2시간 혈당이 300.1mg/dL에서 퇴원 3개월 후 262.5mg/dL로 감소하는 경향이었으나 실험군보다 감소의 폭이 적은 경향이었다. 3) 실험군과 대조군의 입원 시 당화혈색소는 각각 10.3%와 9.7%로 유의한 차이가 없었으나,퇴원 3개월 후 실험군은 7.5%로 대조군의 9.1% 보다 유의하게 감소하였다. 4) 실험군의 입원 시 당뇨지식 점수는 실험군이 12.1점 대조군은 12.0점으로 유의한 차이가 없었으나 퇴원 시는 실험군이 15.5점으로 대조군의 14.6점 보다 높은 경향이었다. 5) 재원일수는 실험군이 8.4일로 대조군의11.0일 보다 유의하게 적었다. 결론 : 따라서 당뇨병 환자를 위한 CP는 재원일수의 감소뿐만 아니라 환자의 자가관리에 대한 체계적인 교육과 개선의 기회를 가짐으로써 장기적인 혈당 조절의 향상을 도모할 수 있는 효과적인 방법이라고 생각한다. Background: The aim of this study was to examine the effects of the critical pathway for the admitted patients with type 2 dia betes me llitus on glycemic control, the knowledge on the disease, and the length of hospital stay. Methods: 89 diabetic in-patients were applied with the 1 week critical pathwa which was consisted of intensive education program for self-management of diabetes me llitus such as glucose monitoring, excercise prescription, diet control, self-a djustment of the drugs and so on. The results were compared with 22 diabetic inpatients who were treated with conventional way. We assessed the effects of critical pathway on the degree of glycemic control, the knowledge on the disease, and the length of hospital stay. Results: Although fasting and postprandial 2 hours blood g lucose levels did not showed sta tistically significantd ifference between critical pathway group and conventional group on discharge , HbA1c was significantly decreased in critical pathwa group compared with the conventional group (7.5±1.8% vs 9.1±2.6%) on 3 months after discharge . Knowledge on the disease tended to increase in critical pathway group compared with the conventional group on discharge. The Length of hospital stay was significantly decreased in critical pathway group compared with the conventional group (8.4±2.8day vs 11.0±3.9da ) Conclusion: These results showed that critical pathway for the patients with diabetes mellitus might be a usefulway for improving the long term glycemic control through motivation, enhancing the knowledge on the disase as well as reducing the length of hospital stay.

保存中인 市亂 및 加工亂의 微生物學的硏究

朴炯淑,文允熙 경성대학교 1984 부산수산대학 논문집 Vol.5 No.2

市亂는 4℃에서, 加工亂는 室溫에 保存하면서 生菌數와 大腸菌群을 測定한 結果는 다음과 같다. 市亂의 生菌數는 冷藏 4일째까지는 試料 모두가 食品衛生法 基準治인 50,000/㎖ 以下였고, 5일째는 1種이 63,000/㎖였다. 加工亂는 7週까지 모두 法的 基準値 以下였고 8週째 1種이 71,000/㎖였다. 大腸群菌은 市亂인 경우 冷藏 7일까지 4種이 음성이었고 2種은 大腸群菌이 檢出되었는데 IMViC test 結果 Enterobacter aerogenes와 Escherichia coli로 各各 判定되었다. 加工亂는 保存 10週까지 大腸群菌이 檢出되지 아니 하였다. This experiment was carried out to determine the bacteriological qualities of the market milk during the period of 7days at 4℃ and theprocessed milk during the 10weeks at room temperature. The results obtained are as follows. The number of live bacteria per milliliter of the all market milk until 4th day at 4℃ were below the regulation number of 50,000, but only one sample showed 63,000/㎖ until the 5th day. The number of livebacteria per milliliter of the all processed milk until the 7weeks at room temperature were below the regulation number, but only one sample showed 71,000/㎖ the 8th weeks. The number of coliform group bacteria per milliliter of the 4 kinds market milk until 7th day at 4℃ were negative, but the 2 kinds were showed coliform group bacteria the Enterobacter aerogenes and Escherichia coli respectively. Processed milk showed negative results in coliform group bactera until 10th weeks at room temperature.