제 1대구치와 제2유구치의 교합면 양상에 관한 연구

전소희,백병주,김재곤,양연미 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.1

형태학적으로 아주 유사한 상, 하악 제2유구치와 제1대구치의 교합면 형태를 분석하고자 정상교합의 유치열기 아동(Hellman dental age ⅡA) 100명(남자 50명, 여자 50명)과 영구치열기의 성인(Hellman dental age ⅣA) 86명(남자 43명, 여자 43명)을 대상으로 하였다. 상, 하악 제2유구치와 제1대구치의 상, 하악 석고모형의 3차원 형상 data로부터 각 교두정간 거리, 교두정을 최소한의 오차로 지나는 평면과 교합면사이의 체적, 평면에서 교두정간 까지의 방향별 Section curve를 구하여 다음과 같은 결론을 얻었다. 1. 형성된 표준평면과 각 교두정과의 거리에 관한 오차는 하악 제2유구치에서 남자 0.05-0.09mm, 여자 0.04-0.09mm로서 제일 작았다. 2. 각 교두정간의 거리는 하악 제2유구치와 제1대구치에서 남자가 크게 나타났다. 특히 제2 유구치에서는 유의성이 존재하였다(p<0.05). 3. 남녀 모두에서 사주 교두거리를 제외하고, 상악 제2유구치는 원심 협측교두와 설측교두 사이가, 하악 제2유구치는 원심교두와 원심 설측교두 사이가, 상악 제1대구치는 근심 설측교두와 협측교두 사이가, 하악 제1대구치는 원심 설측교두와 근심 설측교두 사이의 거리가 가장 크게 측정되었다. 4. 제2유구치와 제1대구치에 교합면 체적은 하악에서 크게 나타났고, 영구치가 1.40-1.75배 값을 보였으며(p<0.05), 남녀간에서는 남자가 큰 값을 보이긴 하였지만 통계적인 유의성이 없었다. 5. 대부분의 경우 유치열에서 보다 영구치열에서 section curve가 넓고 깊었으며 교두사이의 사선거리를 제외하고 상악의 경우 근심 협측과 설측교두 사이에서 유치열과 영구치열 모두에서 가장 깊은 section curve를 이루었으며 하악에서는 영구치열은 원심 협측과 원심교두사이 유치열은 원심 설측과 원심교두 사이에서 가장 깊은 section curve를 이루었다. The purpose of this study was to analyze the morphometrics of primary second molar and permanent first molar. Samples were consisted of normal occlusion in the primary dentition(50 males and 50 females) and permanent dentition(43 males and 43 females). Their upper and lower plaster casts were used and their measuring points wore decided, through 3-dimensional laser scanning(3D Scanner, DS4060, LDI, U.S.A.), fitting standard horizontal plane were made for measuring the intercuspal distance, volume of intercuspal area and section curve. The results were as follows; 1. Average distance from the fit plane to the cusp tips of mandibular primary second molar was smaller than any other tooth. (0.05-0.09 mm in male and 0.04-0.09 mm in female). 2. Intercuspal distances of mandibular primary second molar and permanent first molar were larger in male than in female. Especially, there was statistical significance in primary second molar(p<0.05). 3. Intercuspal distance between distobuccal and distolingual cusp was larger in maxillary primary second molar, except cross intercuspal distances. And distances between distal and distolingual cusp, in mandibular primary second molar, between mesiolingual and mesiobuccal cusp, in maxillary first molar, and between distolingual and mesiolingual cusp, in mandibular first molar were larger than any other intercuspal distance 4. Volume of intercuspal area of primary second molar and permanent first molar was larger in mandible than in maxilla and that of' permanent first molar was 1.40-1.75 times of primary second molar (p<0.05). Also it was larger in male than in female, but there was no statistical significance. 5. In most cases, section curves were wider and deeper in permanent dentition than in primary dentition. Except cross intercuspal distances, in maxilla, section curve between mesiobuccal and mesiolingual cusp was the deepest in both dentition. In mandible, section curve between distobuccal and distal cusp was the deepest in permanent dentition and between distolingual and distal cusp was the deepest in primary dentition.

Chlorpromazine이 백서 해마에서 전기경련 충격에 의한 MAPK 타이로신 인산화에 미치는 영향

주연호,정성훈,전송희,강웅구,김용식,김상욱,박주배 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.2

Object : In order to examine the interaction mechanisms of electroconvulsive shock(ECS) and antipsychotic drug at the level of molecular biology, we observed the effect of chlorpromazine pre-treatment on the activation of mitogen activated protein kinase(MAPK) induced by electroconvulsive shock(ECS) in rat hippocampus Method : Male Sprague-Dawley rats were divided into 2 groups. To the experimental group chlorpromazine(20㎎/㎏) was given intraperitoneally, and to the control distilled water was given instead. Thirty minutes later, ECS was given and the hippocampus was dissected out 2 minutes thereafter. Immunoblotting with antiphosphotyrosine antibody was carried out, and the signal intensity at 42kDa band was quantitized using densitometer. The obtained result was compared by student t-test between the experimental and the control group. The absolute amount of MAPK was measured by immunoblotting with anti-MAPK antibody. Result : The tyrosine phosphorylation of MAPK reached peak at 2 minutes after ECS. However, in the chlorpromazine pre-treated group, the peak level of MAPK tyrosine phosphorylation was significantly attenuated(t=-3.12, df=14, p=0.008) compared to the control. In contrast to this, the absolute amount of MAPK did not differ between the pretreated and the control group. Conclusion : Chlorpromazine attenuated the tyrosine phosphorylation of MAPK by ECS. This finding seems to be related to the fact that chlorpromazine pre-treatment changed the cfos expression by ECS in rat brain. Antipsychotic drug and ECS might interact at the level of MAPK signal transduction system, and this might explained the observed synergistic effect of two treatment modality.

금연구연 지정에 대한 공공기관 근무자의 태도

최연희,전은영,김현미 慶山大學校 保健福祉硏究所 2003 保健福祉硏究 Vol.8 No.-

The purpose of this study is to investigate the attitude of public works on the nonsmoking areas. The subjects were a volunteer sample of 436 public workers in Daegu city. Data was collected through interviews and questionaires from March 10 to May 9, 2001, and analyzed by frequency, percentage, chi-square test and multiple logistic regression, using a SPSS program. The results of this study were as follows: Smokers of the subject group accounted for 47.9%, and smokers who smoke one pack of cigarettes per day and a cigarette to its two-thirds length was the most. 42.6% of smokers have positive attitude to quit smoking, but 36.6% has no intention to quit. Among the subjects who answer 'yes' to designate the nonsmoking area were 63.3%. In the designated places of nonsmoking area within public workplace, 'elevator' showed the highest(95.0%), 'cafeteria'(73.0%), 'physical-training room'(71.6%), and 'passage'(66.4%). For designation of nonsmoking areas, nonsmokers were more positive than smokers and the difference was statistically significant. To designated the factors influencing attitude of public workers on nonsmoking areas, logistic regression analysis has been done. According to the results of this analysis, the volume of smoking and a job barrier being due to cigarette smoking were selected as significant factors. In conclusion, more smoking and health education for public workers is needed to reduce the rate of national smoking and allow people to have a good smoking attitude. It is required to arrange an institutional system who can strictly public workers' smoking in their offices.

여대생의 생활습관 및 스트레스가 변비에 미치는 영향

문지희,전혜연,강나영,김희정,배나영,양아롬,왕세미,하주영,이자형 이화여자대학교 간호과학대학 2004 이화간호학회지 Vol.- No.38

The purpose of this research is to analyze relationships among the habitual life, stress, and constipation and to help prevent and improve the constipation among women's university students. This is a descriptive interrelated research that has targeted women's university students. The data had been collected for 10 days, from December 22, 2003 to December 31, 2003. The survey was carried out to the 295 women's university students that had been randomly selected by visiting four-year-course colleges and universities in Seoul. The survey consists of 78 questions: five questions on the general trait, 11 questions on the habitual life, 51 questions on the stress, and 11 questions on the constipation. There are seven questions on the dietary life, four questions on exercising, and Shin Jung Ran's survey(2003) and Lee Ji Jung's survey(2001) was used as a reference. Yoon Ho Yul's five grade stress barometer(1996) was also used to measure the amount of stress. The collected data was analyzed by a real number, percentage, the arithmetical mean, the standard deviation, t-test, x²test using SPSS 10.00 for Windows Program. Results are as follow 1. Four to six cups of daily water intake was the highest by 50.0%. Students not have breakfast(55.7%) mostly because they did not have enough time(62.6%). Dinner was the most overeated meal by 72.3% and the most preferred food was meat by 42.0%. In the questions related to exercising, more than half of the students answered that they hardly do not exercise(58%), work out for less than 30minutes(67.3%), and exercised lightly(75.3%). 2. Students were suffering from stresses due to the personal relations(51.36±14.0426), scholastic achievement and personal direction(24.93±8.3037), financial conditions and family matters(20.28±8.1718) and social circumstances(2.7262). 3. In the defection part, the student's reply that they have more than five times of bowel movement on a weekly basis(48.3%), and that it takes three to five minutes to defecate(41.3%) were the highest. More than half of the students answered that their one time excrement quantity was between 30 grams to 60 grams(72.3%) and that it was normal(68.7%). In a question asking how it feels after the defecation(students were allowed to choose more than one answer), relieved and refreshed was the highest by 66.6%, an uncomfortable followed by 42.8%. 4.4% of the students answered that they suffer from strong abdominal pain during the defecation. The rest of the students answered that they do not have stomachache or that it was normal. The students were classified into the constipation group of 103 people(34.9%) and the normal group of 192 people(65.1%) under the devised definition of this research. 4. Students that live in dormitories and do their own cooking were more likely to have constipation than those that live in private residence or in a lodgins. 5. The research showed that there is a mutual relation between water in a day intake and the constipation. It means that the lesser water students drink, the more they suffer from the constipation. The number of times a student had a meal everyday and the constipation was interrelated. If a student had lesser or irregular meals in a day, they had more constipation. Preferred food and constipation was also interrelated. Students that preferred vegetable, fruit, and dairy products were more likely to belong in a normal/general group. 6. By dividing the stress factors into the lower categories, we were able to see that the total stress(t-2.063, p-0.040), personal relations(t-2.316, p-0.021), scholastic achievements and personal directions(t-20127, p-0.034) had mutual relation with the constipation. The constipation group(120.27±30.2708) was suffering from stronger level of stress than the normal group(112.97±28.1466). Through this study, we were able to verify that the few general traits, habitual life, and stress of the women's university students have mutual relations with the constipation.

김치 관련 연구문헌의 분류분석 및 김치연구의 동향 (Ⅲ)

최홍식,김재이,민병태,전정태,공연희,홍정진,김나영 부산대학교 김치연구소 2002 김치의 과학과 기술 Vol.8 No.-

About 200 research papers and patents on kimchi(Korean fermented vegetable food) published In the years of 1997-2001 were collected and analyzed for the classification and review. This article covers the classified topics on the natures and kinds of raw materials, fermentation and related microorganisms, processing / preservation, kimchi packaging, biochemical changes, enzymes, quality, food chemistry, functional klmchi, general consideration on kimchi, and also some research nerds In the future.

Cooperative interactions between TLR2 and TLR4 in Murine Klebsiella pneumoniae infection

Hee-Yeon Jeon,Jong-Hyung Park,Jin-Il Park,Jun-Young Kim,Sun-Min Seo,Seung-Hoon Ham,Eui-Suk Jeong,Yang-Kyu Choi 한국실험동물학회 2017 한국실험동물학회 학술발표대회 논문집 Vol.2017 No.2

Synergistic effect of Entolimod and Paclitaxel on cancer cells

Hee-Yeon Jeon,Jong-Hyung Park,Jin-Il Park,Jun-Young Kim,Sun-Min Seo,Seung-Hoon Ham,Yang-Kyu Choi 한국실험동물학회 2016 한국실험동물학회 학술발표대회 논문집 Vol.2016 No.08

Cooperative Interactions between Toll-Like Receptor 2 and Toll-Like Receptor 4 in Murine Klebsiella pneumoniae Infections

( Hee-yeon Jeon ),( Jong-hyung Park ),( Jin-il Park ),( Jun-young Kim ),( Sun-min Seo ),( Seung-hoon Ham ),( Eui-suk Jeong ),( Yang-kyu Choi ) 한국미생물생명공학회(구 한국산업미생물학회) 2017 Journal of microbiology and biotechnology Vol.27 No.8

Klebsiella pneumoniae is an opportunistic and clinically significant emerging pathogen. We investigated the relative roles of Toll-like receptor (TLR) 2 and TLR4 in initiating host defenses against K. pneumoniae. TLR2 knockout (KO), TLR4 KO, TLR2/4 double KO (DKO), and wildtype (WT) mice were inoculated with K. pneumoniae. Mice in each group were sacrificed after either 12 or 24h, and the lungs, liver, and blood were harvested to enumerate bacterial colonyforming units (CFU). Cytokine and chemokine levels were analyzed using enzyme-linked immunosorbent assay and real-time PCR, and pneumonia severity was determined by histopathological analysis. Survival was significantly shortened in TLR4 KO and TLR2/4 DKO mice compared with that of WT mice after infection with 5 × 103 CFU. TLR2 KO mice were more susceptible to infection than WT mice after exposure to a higher infectious dose. Bacterial burdens in the lungs and liver were significantly higher in TLR2/4 DKO mice than in WT mice. Serum TNF-α, MCP-1, MIP-2, and nitric oxide levels were significantly decreased in TLR2/4 DKO mice relative to those in WT mice, and TLR2/4 DKO mice showed significantly decreased levels of TNF-α, IL-6, MCP-1, and inducible nitric oxide synthase mRNA in the lung compared with those in WT mice. Collectively, these data indicate that TLR2/4 DKO mice were more susceptible to K. pneumoniae infection than single TLR2 KO and TLR4 KO mice. These results suggest that TLR2 and TLR4 play cooperative roles in lung innate immune responses and bacterial dissemination, resulting in systemic inflammation during K. pneumoniae infection.

[P8-301] Antimutagenicity, Cytotoxicity and Antibacterial activity of ethanol extract from Schizandra Chinensis Baillon

Yeon-Hee Jeon,Mi-Hye Park,Mee-Ra Kim 한국식품영양과학회 2008 한국식품영양과학회 학술대회발표집 Vol.2008 No.10

Quality Characterization of Commercial Flour and Color Wheat (Arriheuk)

Hee-Yeon Jin,Sung-Hee Jeon,Seok-Geun Jeong,Young Youn 한국식품영양과학회 2019 한국식품영양과학회 학술대회발표집 Vol.2019 No.10