한국인 관상동맥의 변화양상에 대한 형태학적 연구

권태정,이상용,이한영,고영창,권기석,조재홍,김태공,김유훈,조갑래,서중석,이원태 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

레지스탕스 트레이닝에서 고속도 운동이 근횡단 면적 및 운동속도에 미치는 영향

이신언,조규상,한권상 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.2

A conducted to determine 1) the effect of high-velocity mowement in resistance training with a constant load on the velocity of movement after training and 2) the differences in the effect on muscle hypertrophy according to training velocity. Fourteen of the total subjects (male ; n=10, female ; n=7) were placed in the experimental group and agreed to participate in 8 weeks of training sessions(4 times a week). Five of the 17 subjects were in control a group before the training session. Subjects perfrmed elbow extension and flexion exercise using 50% of one repetitions and 30s of rest was taken between the sets. The subjects in the experimental group trained their arms using two different protocols ; one was high-velocity movement performed as rapidly as possibl(Type R), the other was low-velocity movement performed at a constant and slow velocity(Type R), the other was low-velocity movement performed at a constant and slow velocity(Type R), the other was low-velocity movement performed at a constant and slow velocity(Type S). Isokinetic torque in elbow flexion was measured at angular velocities of 60, 180, 300 deg/s, respectively, during elbow flexion performed under different constant loads of 0, 30, 50% 1 RM, and the muscle cross-sectional area(CSA) of the elbow flexor was determined before and after training. It was found that Type R did not increased isokinetic torque at 300 deg/s significantly after training. However, the increase in angular velocity of elbow flexion in Type R exercise tended to be higher than in Type S exercise. The increased in CSA [Type S ; 11.2%, Type R ; 14.2%] was significantly higher in Type R exercise(p<.05). These results suggest that high-velocity movement with a constant load in resistance training might increase the angular velocity of movement in the same mode, but might not produce a change in isokinetic strength, which involves a different mode of muscle contraction. Muscle hypertrophy would be induced to a greater extent by. high-velocity movement than by low-velocity movement in resistance training with a constant load.

고령자의 근력 및 전신이동능력과 일상생활의 주관적인 활동능력과의 관련성 분석

이신언,조병섭,한권상 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.6

The purpose of this study were (1) to determine the changes in functional fitness with aging, and (2) to assess the relationship of muscular strength and locomotion ability with subjective functional fitness. The subjects were 479 Korean women(65+ years) living in Seoul, Taegu, and Jinju cities. Korea. The average age was 72.0±4.8. Thirteen objective functional fitness items and 11 subjective functional fitness questionnaire items associated with their daily living were measured. Results of data analysis indicated that the muscular strength and locomotion ability decreased considerably with aging. The relationship between the objective functional fitness and the subjective functional fitness was significant in 10 items. It is suggested that maintenance and promotion of muscular strength and locomotion ability may be important in order to raise the level of independence in daily living of older Korean women.

후막 전계발광소자(Electroluminescence)의 제조와 발광특성

정영호,김병권,박조용,명광식,Khatkar, S.P.,Liang, Yujun,한상도 경북대학교 센서기술연구소 2002 센서技術學術大會論文集 Vol.13 No.1

내경계막을 제거하지 않은 황반원공의 수술적 폐쇄 후의 황반 혈관의 이동

Han Jo Kwon,Sung Who Park,Ji Eun Lee 한국망막학회 2017 Journal of Retina Vol.2 No.2

Purpose: To compare topographic changes in the macula after closure of idiopathic macular hole both with and without internal limiting membrane peeling. Methods: This study enrolled patients with stage 2 idiopathic macular hole with a diameter less than 300 μm who had undergone vitrectomy for macular hole closure from January 2012 to January 2016: four eyes of four patients (group 1) without internal limiting membrane peeling and 16 eyes of 16 patients (group 2) with internal limiting membrane peeling. A custom program was developed to analyze displacement of retinal vessels in the macula. The grid comprised two concentric rings of different sizes, each containing eight sectors, and displacement of retinal vessels in each sector was compared. Mean vector distance and angle of retinal vascular displacement of each zone (medial, lateral, superior, and inferior) was calculated from the combination of each sector and compared between the two groups. Results: Preoperative mean macular hole diameter in groups 1 and 2 was 218.8 ± 38.9 μm, and 218.6 ± 38.1 μm, respectively (p > 0.05). The average displacement distance of retinal vessels in group 1 was 3.4 μm with 38.7º from the posterior pole, while the inner and outer concentric rings barely moved (5.5 μm, and 1.4 μm, respectively). However, the average displacement distance of retinal vessels in group 2 was 45.9 μm with 0.9º from the posterior pole, and the inner (59.0 μm, 2.8º) and outer rings (32.9 μm, -2.4º) shifted to the nasal side. Retinal vascular displacement appeared to be significantly lower in the group without internal limiting membrane peeling compared to the group with internal limiting membrane peeling. Conclusions: Retinal vascular displacement is minimal after vitrectomy without internal limiting membrane peeling in cases of small macular hole, which supports the hypothesis of previous studies that the internal limiting membrane contributes to structural maintenance of the macula and inhibits macular displacement. 목적: 내경계막을 제거하지 않은 황반원공 및 내경계막을 제거한 황반원공 폐쇄 후 망막혈관의 위치를 분석하여 후극부의 지형학적 변화의 차이를 조사하였다. 대상과 방법: 특발성 2기 전층 황반원공 중 원공직경이 300 μm 이하인 환자들로 유리체절제술을 하였지만 내경계막 제거술을 시행하지 않고 황반원공이 폐쇄된 환자 4명 4안(1군)과 내경계막을 제거하고 황반원공이 폐쇄된 16명 16안(2군)을 대상으로 하였다. 혈관이동을 분석하기 위해 제작된 프로그램을 이용하였다. 8개 구획으로 나눠진 2개의 동심고리로 이루어진 격자로 각 구획을 조사하였고, 각구획 중심에서 가장 가까운 혈관분지의 위치 차이를 측정하였다. 각 구획의 조합으로 이루어진 영역(내측, 이측, 상측, 하측)에서 혈관이동 벡터의 평균 크기와 각도를 계산하고 두 군 간에 비교하였다. 결과: 수술 전 1군의 원공 직경은 218.8 ± 38.9 μm, 2군의 원공 직경은 218.6 ± 38.1 μm로 두 군 간의 차이는 없었다. 1군의 평균 혈관이동은 후극부에서 38.7˚ 각도로 3.4 μm였다. 안쪽 원뿐만 아니라 바깥 원의 이동도 거의 없었다(각각 5.5 μm, 1.4 μm). 반면 2군의 평균 혈관이동은 후극부에서 0.9˚ 각도로 45.9 μm였고 안쪽 원(59.0 μm, 2.8˚) 및 바깥 원(32.9 μm, -2.4˚)도 비측으로 이동하였다. 1군의 술 후 혈관이동은 내경계막을 제거한 군에 비해 모든 영역에서 거의 이동이 없었다. 결론: 작은 황반원공에서 내경계막을 제거하지 않는 경우 혈관 이동은 매우 작으며, 내경계막이 황반 이동을 억제하는 지지구조 역할을한다는 이전 연구 결과에서 제시한 주장을 뒷받침한다.

단독중심오목형성부전의 빛간섭단층혈관영상 소견

Han Jo Kwon,Jae Jung Lee,Sung Who Park,Ji Eun Lee 한국망막학회 2017 Journal of Retina Vol.2 No.2

Purpose: To describe optical coherence tomography angiography (OCTA) findings in two cases of isolated foveal hypoplasia. Case summary: (Case 1) An eight-year-old girl presented with amblyopia and exotropia. Optical coherence tomography demonstrated no central concavity in the foveal area with inner retinal layers present. OCTA revealed that lower central retinal vessel density was lower than peripheral retinal vessel density in the deep vascular plexus but not in the superficial plexus. (Case 2) A 14-year-old boy presented with absence of foveal reflex in both eyes. On OCTA, retinal vessel density of the superficial plexus was similar throughout the macula, while lower retinal vessel density was noted in the foveal region than in the parafoveal region of the deep plexus. Conclusions: OCTA is useful for characterizing foveal hypoplasia. Furthermore, the disparity between deep and superficial retinal vessel density supports the theory of arrested foveal development, in which displacement of deep retinal tissue precedes inner retinal displacement.

고도근시 열공망막박리 공막돌륭술의 해부학적 성공의 예후인자

권한조(Han jo Kwon),신민규(Min Kyu Shin),박성후(Sung Who Park),변익수(Ik Soo Byon),이지은(Ji Eun Lee),엄부섭(Boo Sup Oum) 대한안과학회 2016 대한안과학회지 Vol.57 No.10

목적: 고도근시 열공망막박리 환자의 공막돌륭술에서 해부학적 성공에 영향을 주는 인자를 알아보고자 하였다. 대상과 방법: 2009년 1월부터 2013년 10월 사이 안축장 26.0 mm 이상 혹은 -6.0디옵터 이하의 고도근시 환자들 중 열공망막박리로 공막돌륭술을 시행한 환자의 의무기록을 후향적으로 분석하였다. 백내장과 유리체절제술을 포함한 안내 수술 병력이 있는 환자는 대상에서 제외하였다. 해부학적 성공과 나이, 성별, 술 전 최대교정시력, 안축장, 큰열공 유무, 마제형 열공의 유무, 열공의 개수, 중심와 침범 여부 및 망막박리범위와의 연관성을 조사하였다. 결과: 80명 80안이 포함되었다. 평균 나이는 32.3 ± 13.4세, 평균 안축장 길이는 26.753 ± 0.961 mm였다. 총 69안(86.3%)에서 일차수술 후 성공적으로 유착되었다. 단일변수 로지스틱 회귀분석에서 나이(p=0.011), 큰 열공의 존재(p=0.002)와 마제형 열공(p=0.044)의 존재가 해부학적 성공과 관련이 있었으며 다변수 로지스틱 회귀분석에서 나이만이 해부학적 성공에 영향을 미치는 단일 인자였다 (odds ratio=1.086, 95% confidence interval=1.022-1.154, p=0.004). 결론: 고도근시 열공망막박리에서 공막돌륭술을 시행할 경우 나이가 어릴수록 일차수술 후 해부학적 재유착률이 높은 경향을 보였다. 고도근시 열공망막박리에서 나이가 어린 경우는 공막돌륭술을 우선적으로 고려할 수 있다. <대한안과학회지 2016;57(10):1586-1591> Purpose: To assess the prognostic factors associated with anatomical success of scleral buckle (SB) for rhegmatogenous retinal detachment (RRD) in high myopia patients. Methods: The medical records of RRD in highly myopic eyes treated with SB from January 2009 to December 2013 were reviewed retrospectively. Cases with history of intraocular surgery including phacoemulsification and vitrectomy were excluded. Correlations between anatomical success and the parameters of age, sex, preoperative visual acuity, axial length, presence of large tear, presence of horseshoe tear, the number of tears, involved fovea, and extent of detachment were analyzed. Results: This study included 80 eyes of 80 patients. Average age and axial length were 32.3 ± 13.4 and 26.753 ± 0.961 mm, respectively. Sixty-nine eyes (86.3%) were reattached following primary surgery. Univariate analysis revealed that age (p = 0.011), presence of large tear (p = 0.002), and presence of horseshoe tear (p = 0.044) were correlated with anatomical success after SB. Based on multivariate logistic regression analysis, age was the sole independent prognostic factor (odds ratio = 1.086, 95% confidence interval = 1.022~1.154, p = 0.004). Conclusions: A younger age is associated with a higher rate of primary anatomical success of SB for RRD in highly myopic eyes. In young, highly myopic patients with RRD, SB should be considered as the primary procedure. J Korean Ophthalmol Soc 2016;57(10):1586-1591

인산나트륨을 함유한 하제 복용 후 발생한 급성 인산염 신병증 환자

김한조 ( Han Jo Kim ),이병후 ( Byung Hoo Lee ),권순효 ( Soon Hyo Kwon ),전진석 ( Jin Seok Jeon ),노현진 ( Hyun Jin Noh ),한동철 ( Dong Cheol Han ),진소영 ( So Young Jin ) 대한신장학회 2008 Kidney Research and Clinical Practice Vol.27 No.3

Nephrocalcinosis is described as the deposition of calcium crystals in the renal parenchyma that result from prolonged states of hypercalcemia. Recently recognized is the deposition of calcium phosphate in the renal tubular injury by using sodium phosphate cathartics commonly used for the colonic cleansing. This phenomenon was termed phosphate nephropathy. Acute renal failure secondary to phosphate nephropathy has been increasingly recognized as a complication after the administration of sodium phosphate solution for colonoscopy. We report a case of acute phosphate nephropathy following oral sodium phosphate solution to cleanse the bowel for colonoscopy. A renal biopsy showed diffuse tubular calcium deposition.

실험계획법을 이용한 조(Jaw)의 형상최적설계

이권희(Kwon-Hee Lee),방일권(Il-Kwon Bang),한동섭(Dong-Seop Han),한근조(Geun-Jo Han) 한국항해항만학회 2006 한국항해항만학회 학술대회논문집 Vol.1 No.-

컨테이너 터미널에서 컨테이너의 양.하역 작업 시 컨테이너 크레인을 정위치에 고정시키고, 돌풍으로 인해 컨테이너 크레인이 레일방향으로 미끄러지는 것을 방지하는 장치가 레일클램프이다. 쐐기형 레일클램프는 초기에는 작은 압착력으로 레일을 압착하다가 풍속이 증가하면 쐐기작용에 의해 압착력이 증가하는 방식을 취함으로서 구조적으로 안정성과 내구성이 높은 장점을 가지고 있다. 본연구에서는 레일클램프의 주요부인 조에 대해 형상최적설계를 수행하였다. 본 논문에서는 솔리드 요소로 유한요소 모델링된 조(jaw)의 경량화 설계를 위하여 강도를 고려하였다. 설계변수로는 조의 측면부의 두께, 조의 중간부의 롤러지지부의 두께, 조의 하단부의 롤러지지부의 두께, 조의 곡면부의 위치로 설정하였다. 본 연구에서는 상용프래그램인 ANSYS Workbench의 최적화 기능을 이용하였다. The rail clamp is the device to prevent that a crane slips along rails due to the wind blast as well as to locate the crane in the set position for loading and unloading containers. The wedge type rail clamp should be designed to consider the structural instability and the durability because it compresses both rail side with large clamping force by the wedge working as the wind speed increases. In this research, there are two methods which are design of experiment and variation technology in used commercial software and shape optimization was performed. The optimum results obtained by the two methods are compared and examined

정상인에서 각막 생체역학인자가 파스칼안압계를 이용한 안구박동크기에 미치는 영향

권한조(Han Jo Kwon),이지웅(Ji Woong Lee),신종훈(Jong Hun Shin) 대한안과학회 2015 대한안과학회지 Vol.56 No.8

목적: 정상인에서 각막 생체역학인자가 파스칼안압계로 측정한 안구박동크기에 영향을 미치는지에 대하여 조사하였다. 대상과 방법: 2014년 1월부터 7월 안과 외래를 방문한 정상인들을 대상으로 파스칼안압계로 안구박동크기를 측정하고 안구반응분석기를 사용하여 각막이력(corneal hysteresis, CH), 각막저항인자(corneal resistance factor, CRF)를 측정하고, 골드만안압, 구면렌즈대응치, 안축장 및 중심각막두께를 측정하였다. 안구박동크기에 영향을 미치는 각막 역학인자 및 다른 안 인자들 간에 관계를 조사하기 위해 단일 및 다중 선형회귀분석을 시행하였다. 결과: 평균 안구박동크기는 2.90 ± 1.04 mmHg, 평균 각막이력 및 각막저항인자는 각각 10.44 ± 1.96 mmHg, 11.03 ± 2.21 mmHg였다. 단일회귀분석에서 안구박동크기에 영향을 미치는 인자는 각막저항인자(β=0.280, p=0.049), 골드만안압(β=0.293, p=0.039), 구면렌즈대응치(β=0.283, p=0.047)로 조사되었지만 다중회귀분석에서는 오직 각막저항인자(β=0.686, p=0.042)만 관련이 있었다. 결론: 안관류압을 반영하는 안구박동크기와 각막의 탄성도를 반영하는 각막저항인자가 양의 상관관계를 가지는 것으로 나타났다. 두 인자 간의 관련성은 향후 녹내장에서 안관류압의 변화에 대한 각막 생체역학인자의 영향을 분석하는 데 의미가 있을 것으로 사료된다. Purpose: To investigate the influence of corneal biomechanical factors on ocular pulse amplitude measured using dynamic con-tour tonometry in normal subjects. Methods: The study population consisted of normal subjects who visited the outpatient clinic from January, 2014 to July, 2014. Ocular pulse amplitude was measured using dynamic contour tonometry and corneal hysteresis (CH) and corneal resistance factor (CRF) were measured using an ocular response analyzer. We applied univariate and multivariate linear regressions to in-vestigate the relationship between ocular pulse amplitude and corneal biomechanical factors and other ocular factors. Results: Fifty eyes of 50 patients (average age 52.8 ± 17.2 years) were examined. The average ocular pulse amplitude was 2.90 ± 1.04 mm Hg and the CH and CRF were 10.44 ± 1.96 mm Hg and 11.03 ± 2.21 mm Hg, respectively. In univariate linear re-gression, factors influencing ocular pulse amplitude were ocular pressure based on CRF (β = 0.280, p = 0.049), Goldmann ap-planation tonometry (β = 0.293, p = 0.039), and spherical equivalent (β = 0.283, p = 0.047), while in multivariate linear regression the only factor influencing ocular pulse amplitude was CRF (β = 0.686, p = 0.042). Conclusions: A positive correlation between ocular pulse amplitude reflecting ocular perfusion pressure and CRF reflecting cor-neal elasticity was observed. Correlations between the 2 factors will be an important aspect in future studies regarding the influ-ences of corneal biomechanical factors on ocular perfusion pressure in glaucoma patients.