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      • 1-MCP처리가 '신고'배의 저장에 미치는 영향

        한현희,강충길,이정명 경희대학교식량자원개발연구소 2005 硏究論文集 Vol.24 No.-

        1-MCP 처리가 '신고' 배품종의 상온저장시의 품질에 미치는 영향을 알아보고자 실험을 실시하였다. 수확된 '신고' 배를 1-MCP 1 ppm의 농도로 수확당일, 수확후 1일, 수확후 2일에 각각 처리하고 이후에는 20±2℃의 실온에서 포장 저장하면서 품질관현 요인을 검정하였다. 초기 조사일의 과중에 대한 중간 조사일의 과중감소율에서는 5주차에 수확 1일후 1-MCP 처리구가 가장 감소율이 적었다. 당도에서는 처리간에 차이가 없었다. 경도와 부패과에서는 처리 5주차에서 1-MCP 처리구들이 무처리에 비해 뚜렷하게 경도와 부패과가 적게 발생하였다. 산도에서는 실험 5주차에 무처리가 다른 1-MCP 처리구보다 높았다. 결론적으로 수확직후의 1-MCP처리는 '신고' 배의 저장기간 연장에 효과적이었다. This study was carried out to find out the effects of 1-MCP treatment on the fruit quality of 'Niitaka' pear under room temperature storage conditions. With 1-MCP treatment one day after harvest, the lowest percentage of decrease in the fruit fresh weight was obtained at 5 weeks after the treatment. Soluble solids contents of MCP-treated fruit did not show significant differences among treatments. In comparison with the control, all of 1-MCP treatments showed a slow decrease in fruit firmness and low percentages in rotten fruit rate at 5 weeks after the treatment. At 5 weeks after the treatment, the fruit juice acidity of the control was higher than those from other 1-MCP treatments.

      • KCI등재

        열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

        배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

        Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

      • 통계적 코스트 모델의 유효성 검증방법에 관한 연구

        신진수,김선국,한충희 경희대학교 산학협력기술연구원 건축도시연구부 1997 건축도시연구소논문집 Vol.17 No.-

        A statistical cost model is useful to esimate the construction cost of new projects quickly and precisely in the initial stage of the projects. Traditionally, the precision of regression equations has been evaluated with the coefficient of determination(r^(2)). When the equations are applied to estimate the construction cost of a certain project, the result interpreted using only r^(2) may lead to erroneous predicton. In order to enhance the reliability of regression equations, this paper presents a methodology in which the equations are tested with the possible cost parameters by Monte Carlo simulation. In the research, the methodology is also confirmed to reduce mistakes from the blind use of regression equations.

      • KCI등재

        공동주택의 개인정보보호 개선방안 연구

        한충희(Choong-Hee Han),박순태(Soon-Tai Park),이상준(Sang-Joon Lee) 한국정보보호학회 2018 정보보호학회논문지 Vol.28 No.5

        아파트와 오피스텔은 이미 우리나라 국민 대부분이 거주하는 가장 중요한 주거공간이다. 의식주 중 가장 기본적인 주거를 아파트와 오피스텔과 같은 공동주택이 담당하고 있는 것이다. 이러한 공동주택에 입주하려면 다양한 개인정보를 의무적으로 공동주택의 관리자들에게 제공해야만 한다. 따라서 공동주택의 관리자들에게는 대규모의 개인정보파일이 만들어지고 있고 나름대로의 방식으로 관리하고 있는 실정이다. 만약, 공동주택에서 개인정보유출이 발생된다면 사회적으로 커다란 문제가 될 것으로 예상된다. 본 논문에서는 아파트와 오피스텔에 입주할 때 작성해야 하는 ‘입주자명부’를 수집 조사하여 개인정보 수집과정에서의 법적 준거성을 검토하고 수집항목 최소화, 동의방식 개선 등 다양한 개선방안을 제안하였다. An apartment house and an officetel are already our most important residential space generally. Among food, clothing and shelter, an apartment and an officetel are in charge of a shelter as the most fundamental in our life. To live in an apartment and an officetel, it is necessory for residents to write a lot of informations about themselves. Therefore massive privacy files about apartment"s residents is inevitable and it is managing in its own way. A privacy accident in an apartment houses would be a big society problem. This study examined `tenant list` to find out what it collects and what it’s problems are and proposed some vairous measures about the privacy improvements like items reduction & consent process improvement in an apartment house and an officetel from privacy laws perspective.

      • KCI등재

        봉쇄와 보안장비 수준 기반 정보보호 위험관리 수준 측정 연구

        한충희(Choong-Hee Han),한창희(ChangHee Han) 한국정보보호학회 2021 정보보호학회논문지 Vol.31 No.6

        기존의 정보보호 위험평가 방법은 정보자산의 취약성을 평가하는데 중점을 둔다. 그러나 정보자산의 형태가 바뀌고 새로운 유형의 정보자산이 나오면 그에 대한 평가기준도 추가하거나 삭제하는 등의 보완을 거쳐야 하는 한계가 있다. 기존 방법들은 사이버 위협이 유입되는 경로에 연구가 미흡하다. 특히, 공인 IP를 가지고 있는 웹기반 정보시스템을 대상으로 유입되는 유입경로의 봉쇄를 위한 연구가 매우 부족한 상황이다. 이에 본 논문에서는 BDLA (Blockade and Defense Level Analysis) 기반 정보보호 위험평가 모델의 주요 연구내용을 소개 한다. 또한, BDLA기반 정보보호 위험평가 모델을 적용하여 17개 공공기관의 봉쇄수준과 보안장비 수준 측정을 통하여 정보보호 위험 수준을 연구하였다. Existing information security risk assessment methods focus on evaluating the vulnerability of information assets. However, when the form of information assets changes and new types of information assets emerge, there is a limitation in that the evaluation standards for them are also added or deleted. Existing methods have insufficient research on the path through which cyber threats are introduced. In particular, there is very little research on blocking the inflow path for web-based information systems with public IPs. Therefore, this paper introduces the main research contents of the BDLA (Blockade and Defense Level Analysis)-based information security risk assessment model. In addition, by applying the BDLA-based information security risk assessment model, the information security risk level was studied by measuring the blockade level and security equipment level of 17 public institutions.

      • KCI등재

        사이버 위협 탐지대응시간 모델링

        한충희 ( Han Choong-hee ),한창희 ( Han Changhee ) 한국인터넷정보학회 2021 인터넷정보학회논문지 Vol.22 No.3

        보안관제 분야의 실제 업무활동에 대해서는 거의 연구가 없는 실정이다. 이에 본 논문에서는 보안관제의 위협정보 탐지 대응시간 모델링을 통해 적정 투입인력 규모 산정에 기여하고 최신 보안솔루션 투입시의 효과성 분석 등에 활용할 수 있는 실질적인 연구 방법론을 제시하고자 한다. 보안관제센터에서 수행하는 전체 위협정보 탐지대응시간은 TIDRT(Total Intelligence Detection & Response Time)로 정의한다. 전체 위협정보 탐지 대응시간(TIDRT)는 내부 위협정보 탐지대응시간(IIDRT, Internal Intelligence Detection & Response Time)과 외부 위협정보(EIDRT, External Intelligence Detection & Response Time)의 합으로 구성된다. 내부위협정보 탐지대응시간(IIDRT)는 다섯 단계의 소요시간의 합으로 계산할 수 있다. 본 연구의 궁극적인 목표는 보안관제센터의 주요한 업무활동들을 수식으로 모델링하여 보안관제센터의 사이버 위협정보 탐지대응시간 계산식을 산정하는데 있다. 2장에서는 선행연구를 살펴보고, 3장에서는 전체 위협정보 탐지대응시간의 계산식을 모델링한다. 4장에서 결론으로 끝을 맺는다. There is little research on actual business activities in the field of security control. Therefore, in this paper, we intend to present a practical research methodology that can contribute to the calculation of the size of the appropriate input personnel through the modeling of the threat information detection response time of the security control and to analyze the effectiveness of the latest security solutions. The total threat information detection response time performed by the security control center is defined as TIDRT (Total Intelligence Detection & Response Time). The total threat information detection response time (TIDRT) is composed of the sum of the internal intelligence detection & response time (IIDRT) and the external intelligence detection & response time (EIDRT). The internal threat information detection response time (IIDRT) can be calculated as the sum of the five steps required. The ultimate goal of this study is to model the major business activities of the security control center with an equation to calculate the cyber threat information detection response time calculation formula of the security control center. In Chapter 2, previous studies are examined, and in Chapter 3, the calculation formula of the total threat information detection response time is modeled. Chapter 4 concludes with a conclusion.

      • KCI우수등재

        다중 영향 및 환경정의를 고려한 지역 환경보건수준 평가 사례연구

        박충희(Choong-hee Park),한혜지(Hye-ji Han),이영미(Young-mee Lee),유시은(Si-eun Yoo),정다영(Da-young Jung),추연희(Yeon-hee Chu) 한국환경보건학회 2020 한국환경보건학회지 Vol.46 No.1

        Objectives: Based on the concept of environmental justice, we developed an evaluation model for setting and adopting the direction of environmental health policy using environmental health indicators and statistics from the local governments of Seoul, including environmentally susceptible populations. Methods: We selected a total of 20 variables based on data officially released from national and local governments. After the classification of these variables into the five components of environmental pressure, environmental status, environmental disease, sensitive population, and socioeconomic status, a basic model was constructed to calculate the relative scores of the local governments. Results: The cumulative impact scores for assessment of environmental health status were similar to those of the environmental pressure and status components. The highest five cumulative impact scores fell between 114 and 147. Local government A reported the highest scores and had high environmental pressure, environmental status and socioeconomic status. In addition, the evaluation of the other four local governments indicated that they exhibited above average scores for environmental pressure and environmental status, two did so for environmental disease, and four for sensitive population. Conclusion: We constructed a model to evaluate the environmental health status of the local governments of Seoul based on cumulative impact scores under the concept of environmental justice. As an approach for studying environmentally vulnerable areas through relative ranking, this model was feasible for policy-setting. In addition, this approach would be an analytically useful tool for decision-makers.

      • KCI등재후보

        RAW264.7세포주와 염증생쥐모델에서 항염증(抗炎症) 작용(作用)에 대한 청열활혈탕가계혈등(淸熱活血湯加鷄血藤)의 효과(效果)

        한충희 ( Choong Hee Han ),유동열 ( Dong Youl Yoo ) 대한한방부인과학회 2005 大韓韓方婦人科學會誌 Vol.18 No.3

        Purpose: The Purpose of this research was to investigate the effects of Cheongyeolhawlhyeoltanggagyehyeoldeung (CYHHT) on anti-inflammatory effects. Methods: As for the parameters of inflammation, levels of several inflammatory cytokines and chemical mediators were determined in mouse lung fibroblast cells (mLFC) and RAW264.7 cells. Also, changes in pathological features by drug treatment were investigated in the in vivo edema-induced rats by carrageenin /arachidonic acid or in the colitis-induced mice by DSS treatment. Results: The cytotoxicity of CYHHT on mLFC and RAW264.7 cells was not observed at 100, 50, 10, and 1㎍/㎖ of CYHHT treatments. IL-1β, IL-6 and NOS-II mRNA expression of RAW264.7 cells was inhibited by CYHHT treatments in a dose- dependent manner. CYHHT treatment of RAW264.7 cells inhibited TNF-α and COX-2 mRNA expression. CYHHT treatment of RAW264.7 cells significantly inhibited IL-6 and NO production. CYHHT treatment of RAW264.7 cells inhibited ROS production. CYHHT inhibited rat`s paw edema induced by carrageenin or arachidonate treatment in all concentrations examined. The body weight and colon length of colitis-induced mice were recovered to a normal level by DSS treatment. Clinical disease levels were significantly improved compared to the control animals. CYHHT treatment of colitis-induced mice significantly increased hematological values such as WBC and RBC counts, Hgb and HCT levels, but decreased PLT values. CYHHT treatment of colitis-induced mice decreased IL-6 and TNF-α production significantly CYHHT treatment of colitis-induced mice significantly increased CD3+(T) cell counts. In contrast, CYHHT treatment decreased CD19+ B cell counts and CD3+/CD69+ significantly, and also decreased B/T ratio (%) though not significant. Conclusion: These results indicated that CYHHT could be used for treating diverse female diseases caused by the inflammation.

      • Pilocarpine에 의한 경련 발작과 기억 장애에 미치는 Nitric Oxide의 역할

        한형수,손덕희,박정숙,김중영 慶北大學校 醫科大學 1996 慶北醫大誌 Vol.37 No.4

        목적 : Nitric Oxide(NO)는 신경조직에서 신경전달 물질, 신호전달매개인자 등으로 작용하면서 신경독성, 기억 조절, 세포의 분화와 성장에 관여한다고 알려져 있는 물질이다. 본 실험은 NO가 간질 유발 또는 간질 이후의 손상과 그에 따른 시냅스의 재구성에 어떤 역할을 하리라는 가정 아래 pilocarpine투여 후 나타나는 경련 발작과 기억력 장애에 NO합성 억제제인 LNAME또는 NO의 원료인 L-arginine가 미치는 영향을 검토하고자 하였다. 대상 및 방법 : ICR개의 생쥐수컷을 사용하여 pilocarpine 투여후 6단계로 나누어 경련발작을 관찰하였으며, working memory와 reference memory로 구분하여 기억력검사를 실시하였다. 결과 : 경련 발작에 대한 NO의 역할을 관찰하고자 NO 합성 억제제인 LNAME 전처치하에pilocarpine을 투여한 경우 3 ㎎/㎏/day에서는 항경련 효과를 보이나 300 ㎎/㎏에서는 경련을 조장하는 효과를 나타내었다. 기억력에 대한 실험에서 LNAME는 pilocarpine에 의한 reference memory 장애에는 영향을 주지 못했지만 working memory의 장애는 경감시켰다. L-arginine은 경련 발작에는 영향을 나타내지 않았지만 기억력의 손상은 경감시켰다. 결론 : 이상의 결과는 NO가 pilocarpine에 의한 경련 유발과 기억력 손상에 관여하며, 경련과 기억력 손상에 대한 NO의 작용은 다양하게 나타날 수 있음을 시사한다. The role of nitric oxide in the genesis of pilocarpine-induced seizure and seizure-related memory deficit was studied using LNAME, a nitric oxide synthesis inhibitor, and L-arginine, substrate for nitric oxide synthase. After pretreatment with LNAME or L-arginine, pilocarpine was administered intraperitoneally. LNAME (300 ㎎/㎏) or L-arginine (500 ㎎/㎏) had no effect on the behavioral seizure activity and onset of seizure activity. But LNAME(3 ㎎/㎏) showed anticonvulsant property. Memory was tested with reference and working memory version of Morris water maze following pilocarpine treatment and showed memory deficit. Deficit in reference memory was prevented by L-arginine and deficit in working memory was prevented by LNAME and L-arginine. These Results show that nitric oxide plays a dual role in the induction of seizure by pilocarpine and pilocarpine-induced memory deficit.

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