유방암과 섬유선종의 방사선학적 소견 : 유방 단순촬영술과 유방 초음파검사 소견의 비교 연구 Studies on mammographic and ultrasonographic findings evaluation

임한혁,최득린,고은석,이혜경,임철완,이상진,홍현숙,최교창,김영화,박재성 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

Purpose : To evaluate the utility of mammography and ultrasonography in study of morphologic differential diagnosis between malignant and benign mass. Materials and Methods : Average age of patients with breast cancer was 48.4 year-old, and that of fibroadenoma was 29.4 year-old. The equipments used for examination were MF-159 high frequency mammography(Bennet Co.) and Acoustic image 5200S. We evaluated mammographic findings about breast parenchymal pattern, calcification, margin and size of the mass associated tumor nature, and ultrasonographic findings about shape, height and width, internal homogenicity and echo pattern, wall contour, boundary echo, and posterior shadow in breast mass. Thirty-seven of mammographic findings and 34 cases of ultrasonogreaphic findings in pathologically proven breast cancer and 34 case of mammographic findings and 71 cases of ultrasonographic findings in breast fibroadenoma were reviewed retrospectively. Results : In mammographic study, the parenchymal patterns of breast cancer according to Wolfe classification were NI(16.2%), PI(24.3%), P@(37.8%), and DY(21.6%) and those in fibroadenoma were NI(3.1%), Pl(11.7%), P2(35.2%),and DY(50%). Mammographic findings about presence of calcification were as follows; only calcification(16.2%), only mass(51.3%), and mass with calcification(32.5%) in breast cancer, and only mass(91.2%), mass with calcification(8.8%) in fibroadenoma. The features of mass margins were classified as ill-defined margin(45.9%), well-defined(5.4%), and well-defined with partial spiculation(48.6%) in breast cancer and ill-defined(20.5%), well-defined(73.5%), and well-defined with partial spiculation(5.8%) in fibroadenoma. The mass were grouped by size; 1-2cm(37.8%), 2-4cm(45.9%), and 4-6cm(16.3%) in breast cancer and 1-2cm(79.4%), 2-4cm(17.6%), and 4-6cm (3.0%) in fibroadenoma. On ultrasonographic study, the shape of masses in breast cancer were lobulated(82.3%),oval(14.7%), and round(3.0%),and those in fibroadenoma were lobulated(14.0%), oval(57.7%), and round(18.3%). The cases that the height was longer than width were 32.3% in breast cancer and 0% in fibroadenoma. The findings about homogenecity and echo patterns were as follows; hypoechoic(52.9%) and mixed(47.1%) in breast cancer and hypoechoic(2.8%), hypoechoic(63.4%), and mixed(33.8%) in fibroadenoma. The margin of masses were smooth in 85.9% of fibroadenoma, and irregular in 73.6% of breast cancer. The boundary echoes of masses and decreased posterior echo shadow were seen only in 61.8% and 55.9% of breast cancer, respectively. Conclusion: The margin and calcifications are more clearly delineated on mammography but breast cancer and fibroadenoma, both are more commonly developed in dense parenchymal pattern(P2+DY),and there findings are easily obscured in mammography. So ultrasoography is very useful in these masses evaluation, especially amoung young patients.

Thiobacillus sp. IW.에 의한 황화수소 제거

차진명,고한철,이인화 조선대학교 부설 유전생물공학연구소 1994 유전생물공학연구지 Vol.4 No.-

Thiobacillus sp. IW., capable of oxidizing hydrogen sulfide, was isolated from waste coal mine water around Hawsun in Chunnam province. The isolate was motile gram-negative rod shape, formed spore and grew up to be aerobically facultative chemolithotroph by using energy released from the oxidation of reduced inorganic sulfur compounds. It was found that the optimum thiosulfate concentration for growth was 32mM. The G+C content of the DNA was 65.0 mol%. The isolate had 16:1+17cyc, 16:0 as their major non-hydroxylated cellular fatty acids, 3-OH 12:0 as a hydroxylated fatty acid and also contained unidentified C_18 branched fatty acid. The ubiquinone system in the respiratory chain was Q-9. The cell productivity was 6.25mg/1.h and the isolate grew logarithmically up to 18 hour. The maximum specific growth rate of cell was 0.78h^-1 and generation time was 0.9 hour. In order to oxidize hydrogen sulfide in a bubble column reactor, Thiobacillus sp. IW. was immobilized on Polyvinylpyridine(PVP). 1.2l of broth medium containing 7.5g of immobilized PVP was used as a liquid phase and gas was supplied through the sintered glass distributor under hydrogen sulfide concentration controlled air stream. A Michaelis-Menten equation was applied for kinetics modeling and the maximum removal rate(V_m) and saturation constant(K_s) of hydrogen sulfide were 52.4(g-S/kg-dry PVP.d) and 62.88ppm, respectively.

부산지역 워터프런트의 기후특성에 관한 연구

도근영,이한석,고성철,현번수,유종수 韓國海洋大學校 附設 海洋科學技術硏究所 2002 硏究論文集 Vol.11 No.2

워트프런트는 도심 및 내륙지역과는 다른 독특한 기후특성을 가지고 있으며 이를 고려하지 않고 개발할 경우 시설물의 하자발생, 에너지 및 유지관리비용의 상승을 초래하게 됨은 물론 배후지, 도시기후에 악영향을 미치게 된다. 본 연구는 부산지역의 10개 기상관측지점을 해안선에서 거리에 따라 워터프런트 및 내륙지역으로 분류하고 5년간의 기상데이터를 이용하여 워터프런트의 기후특성에 대해 검토한다. 또한 원터프런트지역임에도 내륙지역과 유사한 기후특성이 나타나고 있는 대연지점을 대상으로 기후특성변화의 원인에 대해 검토한다. The waterfront has distinct climate characteristics different from urban or inland area. These may create not only the rise of energy and maintenance costs for facilities located at waterfront areas, but also negative effects on the climate of the nearby inland area, unless these are treated with particular care. For the present study, the climate characteristics of waterfront were examined with climate data of 10 observation points carefully selected in Busan area. Each weather observation point was classified into either waterfront area of inland area, based on the distance from the coastal line. Special considerations were given to the climate data gathered at the Dae-Yeon weather station because it shows the climate characteristics similar to those of inland area although it is located very near the waterfront area. Results indicates that this peculiar climate condition attributes, at least in part, to the reclamation of frontal coastal area.

-10℃ 조건에서의 열선 및 단열보온 조합양생에 따른 슬래브콘크리트의 온도이력

한상윤(Han, Sang Yoon),정상현(Cheong, Sang Hyun),안상구(Ahn, Sang Ku),고경택(Koh, Kyung Taek),한민철(Han, Min Cheol),한천구(Han, Cheon Goo) 한국콘크리트학회 2011 한국콘크리트학회 학술대회 논문집 Vol.2011 No.11

Candida magnoliae에 의한 에리스리를 생산을 위한 최적 배양환경과 질소원 선별

고은성,문관훈,한기철,유연우,서진호 한국산업미생물학회 2000 한국미생물·생명공학회지 Vol.28 No.6

C. magnoliae M26을 이용하여 천연 감미료인 에리스리톨의 발효생산 환경의 최적화와 대량생산을 위한 산업용 배지의 적용가능성을 검토하였다. 에리스리톨의 발효생산의 최적 조건은 28℃의 발효온도와 초기 pH 7 이었으며, 1 vvm, 500 rpm의 2.5 l jar-fermentor에서의 통기 조건이었다. C. magnoliae M26에 적합한 탄소원을 알아보기 위해 포도당, 과당, sucrose에 대하여 탄소원의 소비 경향과 에리스리톨의 생산성을 알아 본 결과, 포도당이 가장 적합했다. 에리스리톨의 효율적인 대량생산을 위해 전분가공공정의 부산물인 LSW와 CSL가 yeast extract대체 질소원으로의 가능성을 검토하였다. 대체 질소원인 LSW와 CSL은 서로의 발효 양상과 결과는 거의 비슷했고, 대조 실험인 yeast extract 결과 (68.2 g/l)에 비하여 세포성장이 약 1.5배 정도로 세포성장은 촉진되었고 에리스리톨 생산성은 yeast extract결과 (0.966 g/l·h)의 약 90% 정도로 거의 비슷한 에리스리톨 생산성을 보였다. 따라서 LSW와 CSL은 yeast extract 대체 질소원으로 산업화 공정에 사용이 가능한 것으로 판단되었다. Culture conditions and nitrogen sources were optimized for production of erythritol, a natural sweetener, by Candida magnoliae M26. The optimal culture conditions were found to be culture temperature of 28℃, initial pH of 7, aeration of 1 vvm and agitation speed of 500 rpm in a 2.5 l jar-fermentor. Glucose was chosen as the best carbon source based on cell growth and erythritol productivity. Light steep water (LSW) and corn steep liquor (CSL) which are by-products in starch processing from corn were tested as a nitrogen source substitute for yeast extract. The use of either LSW or CSL did not change the fermentation performance. The experimental results using LSW and CSL showed 1.5 times higher in cell growth and almost the same value inerythritol productivity compared with the control fermentation using yeast extract as a nitrogen source. These results suggested that either LSW or CSL could be used as a nitrogen source in a large-scale fermentation for erythritol production.

Actuation of PVDF Cantilever with PEDOT/PSS (DMSO) Electrode Using Ion-Assisted-Reaction

Cheol Su Lee,Jin Soo Joo,Seok-Keun Koh,Sung Han 한국물리학회 2004 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.45 No.3

Bimorph cantilevers were fabricated by using the piezoelectric polymer [poly(vinylidene uoride), PVDF, phase] for the active layers and the highly conducting polymer [poly(3,4-ethylenedioxy thiophene)/poly(4-styrenesulfonate), PEDOT/PSS] for the electrodes. In order to make the hydrophilic layer and diusion barrier on the polymers, the lms were modied by an ion-assistedreaction (IAR) method. The surface energy of the IAR-treated samples was calculated from the measured contact angles. The hydrophilic groups on the IAR-treated samples were veried by Xray photoelectron spectroscopy (XPS) analysis. In order to conrm the penetration of the epoxy adhesive into the PEDOT/PSS (DMSO as solvent) lm, the XPS and the scanning electron microscopy (SEM) images were analyzed. To fabricate the bimorph cantilevers, the two active PVDF layers both having the PEDOT/PSS (DMSO) electrodes were bonded by using epoxy adhesive. The displacement of the cantilevers was measured at the resonance frequency, and the actuation of the device made with the IAR-treated electrode was higher than that of the device made with the pristine electrode.

Kinetics and Mechanism of the Pyridinolysis of Aryl Cyclopropanecarboxylates in Acetonitrile

Koh, Han-Joong,Kang, Suk-Jin,Kim, Cheol-Ju,Lee, Hai-Whang,Lee, Ik-Choon Korean Chemical Society 2003 Bulletin of the Korean Chemical Society Vol.24 No.7

Kinetic studies of the reaction of Z-aryl cyclopropanecarboxylates with X-pyridines in acetonitrile at 55.0 ℃ have been carried out. The reaction proceeds by a stepwise mechanism in which the rate-determining step is the breakdown of the zwitterionic tetrahedral intermediate, $T^{\pm}$. These mechanistic conclusions are drawn base on (i) the large magnitude of ρx and ρz, (ii) the positive sign of ρxz and the larger magnitude of ρxz than normal $S_N2$ processes, (iii) a small positive enthalpy of activation, Δ$H^≠$, and a large negative, Δ$S^≠$, and lastly (iv) adherence to the reactivity-selectivity principle (RSP) in all cases.

層積處理 過程에 있어서 朱木種子 成分의 生化學的 變化(I)

高大植,韓哲洙 전북대학교 농업과학기술연구소 1975 農大論文集 Vol.6 No.-

This study was carried out in order to investigate metabolism by determining the seasonal changes of some chemical substances (sugar, protein, starch, fat and moisture contents) contained in Taxus cuspidate seeds. The results are summerized as follows: 1. Protein and sugar content increased gradually, but sugar content increased rapidly after thirteen-month stratification. 2. Starch and fat content decreased gradually, but fat content decreased rapidly after six-month stratification. 3. The change of each substance greatly depended upon the active metabolisms after the absorption of moisture.

Correlation of the Rates of Solvolyses of Benzhydryl Halides Using an Extended Grunwald-Winstein Equation

Koh, Han-Joong,Kang, Suk-Jin,Kim, Cheol-Ju Korean Chemical Society 2009 Bulletin of the Korean Chemical Society Vol.30 No.2

Rates of solvolyses of benzhydryl chloride ($Ph_2$CHCl, 1) and benzhydryl bromide ($Ph_2$CHBr, 2) in ethanol, methanol, and aqueous binary mixtures incorporating ethanol, methanol, 2,2,2-trifluoroethanol (TFE) and acetone are reported. Solvolyses were also carried out in TFE-ethanol mixtures. Application of the extended Grunwald-Winstein equation led to l value of 1.19 (1), 1.29 (2) and m value of 1.00 (1), 0.77 (2), correlation coefficient of 0.965 (1) and 0.970 (2). Sensitivities (l = 1.19 (1), 1.29 (2) and m = 1.00 (1), 0.77 (2)) were similar to those obtained for several previously studied solvolyses, in which an $S_N$2 pathway is proposed for the solvolyses of benzhydryl halides ($Ph_2$CHX, X = Cl or Br).

공시체 크기 변화에 따른 고성능 콘크리트의 수축특성

한천구(Han, Cheon Goo),金虎林(Jin, Hu Lin),한민철(Han, Min Cheol),강수태(Kang, Soo Tae),고경택(Koh, Kyoung Taek) 한국콘크리트학회 2004 한국콘크리트학회 학술대회 논문집 Vol.2004 No.11