Determination of Corrosion Rates of Reinforcement Steel in Silo Concrete by Electrochemical Method

Haeyong Jung,Sung-Bok Lee,Jin Beak Park,Eunyong Lee 한국방사성폐기물학회 2009 한국방사성폐기물학회 학술논문요약집 Vol.7 No.1

Observation of Ge Bottom Cells in InGaP/InGaAs/Ge Triple-junction Solar Cells

Haeyong Jung,정상현,김창주,전동환,강호관,김호경 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.65 No.7

After growing InGaP/InGaAs/Ge triple-junction solar cells, we prepared two different Ge cellsby etching down to the GaAs buffer layer (sample A) and the AlGaAs layer (sample B). Then, thephotovoltaic properties of these two Ge cells were investigated under various light concentrations inorder to find the factors affecting the overall performance of the triple-junction solar cells. Underconcentrated light, the open-circuit voltage (VOC), fill factor and conversion efficiency were higherfor sample A than for sample B. The external quantum efficiency was shown to have a slightlyhigher value for sample A. Both the tunnel junction layer and the top contact resistance increasedthe series resistance, which also provided defects acting as leakage path. A comparison to previousworks suggests that the conversion efficiency of Ge bottom, if present, is degraded marginally afterthe growth of the full structure of triple-junction solar cells.

Luminescence Properties and Crystallinity of Sm3+-doped NaGd(WO4)2 Powder Phosphors

Jeong, Jung Hyun,Chen, Yeqing,Yang, Hyun Kyoung,Chung, Jong Won,Moon, Byung Kee,Choi, Haeyong,Kim, Jung Hwan Korean Physical Society 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.57 No.6

복사열 반사판의 설계를 위한 광학적 해석 및 실험기법

정해용(Haeyong Jung),송태호(Tae-Ho Song),유승열(Seung-Yeol Yoo) 대한설비공학회 2008 설비공학 논문집 Vol.20 No.8

Radiative heating is suitable for outdoor heating system in windy and cold seasons. Optimal design of the reflector is very important to maximize heat transfer to a specific target area in the open space. The geometrical optical theory can be applied to analyze efficiency of the reflector. Commercial ray tracing computer programs are available only for limited geometries of the reflector. Alternatively, it may be designed and analyzed through an approximated simple lens theory. Two types of reflectors are analyzed using either of these methods. The key issue in this paper is to propose a new illumination experimental method for determination of the radiative efficiency. Optical light source and illuminometer are employed. The calculated efficiency of the reflector is compared with experimental one for checking the reliability. The relative errors between the experimental and analytical results are less than 5%, which proves the validity of this method. Based on these methodologies, a practical reflector and heating lamp unit is developed.

정보시스템 통합단계별 성과측정 모형 및 물리적 통합단계의 측정지표 개발에 관한 연구

정해용(Haeyong Jung),나종회(Jonghei Ra) 한국IT서비스학회 2008 한국IT서비스학회지 Vol.7 No.4

This study aims to develop an integration performance measurement model for each stage of information systems integration. In order to achieve the purpose of the research, first of all, the concepts of IS integration or consolidation are analyzed through theoretical and practical reviews. Also, a number of important studies of domestic and overseas cases about the stage models of IS integration or consolidation are critically reviewed. Second, we proposed three step stage model of IS integration, Physical Integration stage, Application Integration stage, Service Integration stage, and Also proposed the performance measurement model for each stage of information systems integration. Third, especially in case of performance indicators and performance measurement methodology for physical integration stage are illustratively proposed, based upon the case of NCIA (National Computing Integration Agency) in Korea. This study provides the theoretical basis for reasonably deriving the stage model and performance measurement model for each stage of Information Systems Integration, and they are validating through investigating domestic and foreign practices. The results of this study are very likely to contribute to presenting the practical guideline for desirably implementing IS integration or IS consolidation.

정부조직의 정보화교육훈련 체계구축에 관한 연구

정해용(Haeyong Jung),김상훈(Sanghoon Kim) 한국산업정보학회 1999 한국산업정보학회논문지 Vol.4 No.1

계층분석기법을 이용한 정보시스템 평가영역 및 평가항목별 가중치 설정 방안: 공공부문을 중심으로

정해용(Haeyong Jung),김상훈(Sanghoon Kim) 한국데이타베이스학회 2004 Journal of information technology applications & m Vol.11 No.4

생약복합물의 지방세포형성억제 기전규명을 위한 전사체 분석

Haeyong Lee(이해용),Ryunhwa Kang(강련화),Sungmin Bae(배성민),Soo Ahn Chae(채수안),Jung Ju Lee(이정주),Dong-Jin Oh(오동진),Sukwon Park(박석원),Soo Hyun Cho(조수현),Yae Jie Shim(심예지),Yoosik Yoon(윤유식) 한국생명과학회 2010 생명과학회지 Vol.20 No.7

생약복합물인 SH21B는 황금(Scutellaria baicalensis Georgi), 행인(Prunus armeniaca Maxim), 마황(Ephedra sinica Stapf), 석창포(Acorus gramineus Soland), 포황(Typha orientalis Presl), 원지(Polygala tenuifolia Willd), 하엽 (Nelumbo nucifera Gaertner)의 혼합(비율 3:3:3:3:3:2:2)으로 이루어졌다. SH21B는 예로부터 한의학에서 비만의 치료에 사용되어 왔으나 자세한 분자적 메커니즘과 효능에 대한 연구는 이루어지지 않았다. 본 연구진은 선행연구를 통해 SH21B가 지방세포의 분화에서 adipogenesis (지방세포형성)와 관련된 유전자를 조절하여 중성지방의 축적을 억제함을 밝혔다. 본 연구에서는, microarray 기술을 이용하여 adipogenesis의 in vitro 모델인, 3T3-L1 세포에서 SH21B에 의한 지방세포형성 억제의 분자적 기작을 보다 상세하게 연구하고자 하였다. 전지방세포, 분화된 세포 그리고 SH21B에 의해 분화가 억제된 세포의 각각의 유전자 발현을 분석하기 위해 각 시료들에서 total RNA를 분리하여 cDNA를 합성한 후 microarray에 적용시켰다. 그 결과, 각각의 시료들의 비교에서 2배 이상의 유의한 발현 변화를 가지는 2,568개의 유전자를 확보하였다. 이 유전자들에 대해 Hierarchical clustering과 K-means clustering 분석을 진행하였고 서로 다른 양상을 가지는 9개의 군집(cluster)들을 분류하였다. 그 중, SH21B의 첨가에 의해 뚜렷하게 감소(cluster 4, cluster 6 및 cluster 9)하거나 반대로 뚜렷하게 증가(cluster 7와 cluster 8)하는 양상을 보이는 군집들을 따로 선별하여 그 군집들에 포함되어 있는 유전자들을 분석하였다. 선택된 5개의 군집에는 지방세포형성과 세포증식에 관련된 유전자가 다수 포함되어 있었다. Cluster 4, cluster 6 그리고 cluster 9에는 peroxisome proliferator activated receptor gamma γ (PPARγ), CCAAT/enhancer binding protein α (C/EBPα), sterol regulatory element binding transcription factor 1 (SREBF1), adiponectin (ADIPOQ), fatty acid synthase (FASN), lipoprotein lipase (LPL) 등의 지방세포형성 유도 및 관련 인자와 B-cell leukemia/lymphoma6 (BCL6), retinoblastoma 1 (RB1), cyclin-dependent kinase inhibitor 2C (CDKN2c), ras homolog gene family, member B (RHOB) 등의 많은 세포증식 억제 유전자가 포함되었다. 이와는 반대로, cluster 7과 cluster 8에는 β-catenin, cyclin D1 (CCND1), WNT1 inducible signaling pathway protein 2 (WISP2) 등과 같은 지방 세포형성 억제 조절자와 MARCKS-like1 (MARCKSL1), colony stimulating factor 1 (CSF1), discoidin domain receptor family, member 2 (DDR2), leukemia inhibitory factor receptor (LIFR) 등의 세포증식을 유도하는 조절자가 다수 포함되었다. 결론적으로, 이러한 결과들은 SH21B가 지방세포형성과 관련된 조절자 및 세포증식과 관련된 조절자들의 유전자 발현을 조절하여 지방세포형성을 억제함을 제시한다. SH21B is a natural composition composed of seven herbs: Scutellaria baicalensis Georgi, Prunus armeniaca Maxim, Ephedra sinica Stapf, Acorus gramineus Soland, Typha orientalis Presl, Polygala tenuifolia Willd and Nelumbo nucifera Gaertner (Ratio 3:3:3:3:3:2:2). In our previous study, we reported that SH21B inhibited adipogenesis and fat accumulation in 3T3-L1 cells through modulation of various regulators in the adipogenesis pathway. The aim of this study was to analyze the transcriptome profiles for the anti-adipogenic effects of SH21B in 3T3-L1 cells. Total RNAs from SH21B-treated 3T3-L1 cells were reverse-transcribed into cDNAs and hybridized to Affymetrix Mouse Gene 1.0 ST array. From microarray analyses, we identified 2,568 genes of which expressions were changed more than two-fold by SH21B, and the clustering analyses of these genes resulted in 9 clusters. Three clusters among the 9 showed down-regulation by SH21B (cluster 4, cluster 6 and cluster 9), and two clusters showed up-regulation by SH21B (cluster 7 and cluster 8) during the adipogenesis of 3T3-L1 cells. It was found that many genes related to cell proliferation and adipogenesis were included in these clusters. Clusters 4, 6 and 9 included genes which were related with adipogenesis induction and cell cycle arrest. Clusters 7 and 8 included genes related to cell proliferation as well as adipogenesis inhibition. These results suggest that the mechanisms of the anti-adipogenic effects of SH21B may be the modulation of genes involved in cell proliferation and adipogenesis.

A Study on the Gene Expression of Adipogenic Regulators by an Herbal Composition

Haeyong Lee(이해용),Ryunhwa Kang(강련화),Sungmin Bae(배성민),Soo Ahn Chae(채수안),Jung Ju Lee(이정주),Dong-Jin Oh(오동진),Sukwon Park(박석원),Soo Hyun Cho(조수현),Yae Jie Shim(심예지),Yoosik Yoon(윤유식) 한국생명과학회 2010 생명과학회지 Vol.20 No.5

본 연구의 목적은 생약복합제제인 SH21B의 adipogenesis 억제 효능에 대한 상세한 분자적 메커니즘을 3T3-L1 지방세포를 이용하여 밝히는 데 있다. 실험에 사용된 SH21B는 7가지 생약성 천연물질인, 황금, 행인, 마황, 석창포, 포황, 원지 및 하엽으로 이루어졌다. 최근, 본 연구진에 의해 3T3-L1을 이용한 in vitro 연구와 마우스를 이용한 in vivo 연구에서 SH21B의 adipogenesis 억제효능이 밝혀진 바 있다. 본 연구에서는 3T3-L1 지방세포가 분화될 때 작용하는 다양한 지방세포형성 조절자들의 유전자 발현이 SH21B에 의해 어떻게 변하는지 살펴보고자 하였다. 실시간중합효소반응(real time PCR) 기술을 이용하여 SH21B를 처리한 지방세포와 그렇지 않은 지방세포를 비교한 결과, 최종마커인 ADIPOQ와 SLC2A4의 유전자 발현이 SH21B에 의해 급격하게 감소함을 알 수 있었다. 최종 마커의 발현을 유도하는 핵심전사인자인 PPARγ와 C/EBPα의 유전자 발현 역시 SH21B의 처리 시 유의하게 억제되었다. 좀 더 상세한 분자적 메커니즘을 규명하기 위해, 핵심전사인자의 상위에 위치한 다양한 조절자들의 유전자 발현을 분석하였다. 그 결과, 여러 지방세포형성 유도조절자 중, Krox20과 KLF15의 유전자 발현이 SH21B 처리에 의해 유의하게 감소된 반면, C/EBPβ와 KLF5의 유전자 발현은 SH21B 처리에 영향을 받지 않았다. 그리고 지방세포형성 억제조절자인 KLF2와 CHOP의 유전자 발현은 SH21B 처리에 의해 유의하게 증가되었다. 이러한 결과들은 SH21B의 지방세포형성 억제효능이 지방세포의 분화에 작용하는 다양한 상위조절자 중 지방세포형성 유도조절자인 Krox20과 KLF15 그리고 지방세포형성 억제조절자인 KLF2와 CHOP 등의 유전자 발현이 변화되면서 일어나는 복합적인 반응의 결과임을 제시한다. In our previous study, it was reported that an herbal mixture, SH21B, inhibits fat accumulation and adipogenesis both in vitro and in vivo models of obesity. SH21B is a mixture composed of seven herbs: Scutellaria baicalensis Georgi, Prunus armeniaca Maxim, Ephedra sinica Stapf, Acorus gramineus Soland, Typha orientalis Presl, Polygala tenuifolia Willd, and Nelumbo nucifera Gaertner (Ratio 3:3:3:3:3:2:2). The aim of this study was to investigate the detailed molecular mechanisms of the effects of SH21B on various regulators of the adipogenesis pathway. During the adipogenesis of 3T3-L1 cells, SH21B significantly decreased the expression levels of central transcription factors of adipogenesis, such as peroxisome proliferator-activated receptor (PPAR)γ and CCAAT/enhancer binding protein (C/EBP)α. To elucidate the detailed molecular mechanism of the anti-adipogenic effects of SH21B, we examined the expression levels of the various pro-adipogenic or anti-adipogenic regulators of adipogenesis upstream of PPARγ and C/EBPα. The mRNA levels of Krox20 and Kruppel-like factor (KLF) 15, which are pro-adipogenic regulators, were significantly down-regulated by SH21B treatment, whereas the mRNA levels of C/EBPβ and KLF5 were not changed. KLF2 and C/EBP homologous protein (CHOP), which are anti-adipogenic regulators, were significantly up-regulated by SH21B treatment. These results suggest that the molecular mechanism of the anti-adipogenic effect of SH21B involves both the down-regulations of pro-adipogenic regulators, such as Krox20 and KLF15, and the up-regulations of anti-adipogenic regulators, such as KLF2 and CHOP, which results in the suppression of central transcription factors of adipogenesis including PPARγ and C/EBPα.

무선랜 트래픽 분석을 위한 측정 시스템의 설계와 구현

김해용(Haeyong Kim),최낙중(Nakjung Choi),백승민(Sungmin Baek),최양희(Yanghee Choi),이고운(Gowoon Lee),김성만(Sungmann Kim),정한욱(Hanwook Jung) 한국통신학회 2004 한국통신학회 학술대회논문집 Vol.2004 No.11