Identification of the Main Bacteria Contributing to Histamine Formation in Seafood to Ensure Product Safety

Shin-Hee Kim,Jorge Barros-Velazquez,Begona Ben-Gigirey,Jong-Bang Eun,Sang Ho Jun,Cheng-i Wei,Haejung An 한국식품과학회 2003 Food Science and Biotechnology Vol.12 No.4

신규간호사의 임상수행능력 예측요인

신연화,이해정,임연정 한국간호과학회 간호행정학회 2010 간호행정학회지 Vol.16 No.1

Purpose: The purpose of this study was to identify the predictors of clinical competence in new graduate nurses. Methods: The subjects of this study were 238 nurses at 13 general hospitals who have had less than 12 months of nursing experience. The data were collected by structured questionnaire from August 5 to August 31 of 2009 and analyzed by the SPSS Win 12.0 program. Results: The total mean score for clinical competence was 181.05±15.17, critical thinking disposition was 94.65±8.12, and practice environment was 41.00±5.55. There were significant differences of clinical competence according to the GPA (t=-3.58, p<.001), the number of beds in the hospital (t=-3.22, p=.001), instruction by preceptor (t=-2.32, p=.021), and previous experience of clinical practice in the hospital (t=-2.21, p=.028). Additionally, critical thinking disposition and practice environment were positively correlated to clinical competence (r=.50, p<.001; r=.20, p=.002). In multivariate approach, predictors included in this study explained 43% of variance in clinical competence. Significant predictors of clinical competence were critical thinking disposition (β=.50, p<.001), practice environment (β=.14, p=.012), and working duration (β=.13, p=.018). Conclusions: Based on these findings, it is needed that providing supportive practice environment and developing curriculum for enhancing the critical thinking disposition to improve the clinical competence in new graduate nurses.

Benign Adenomyoepithelioma of the Breast: Imaging Characteristics

So Ra Shin,Eun Young Ko,Boo-Kyung Han,Eun Sook Ko,Ji Soo Choi,Haejung Kim 대한영상의학회 2023 대한영상의학회지 Vol.84 No.2

Purpose This study aimed to evaluate the radiological and clinical characteristics of benign adenomyoepitheliomas of the breast. Materials and Methods Over the last 20 years, 120 patients were histologically diagnosed with breast adenomyoepithelioma (AME) at our institution. We excluded 43 patients who were incidentally diagnosed during mastectomy for breast cancer, 28 who underwent percutaneous biopsy without further excision, and 8 who had biopsy-confirmed benign AME and were found to have another pathology after complete excision. We retrospectively reviewed the clinical records and radiological findings of the remaining 41 patients with histologically diagnosed benign breast AMEs after complete excision. Results All 41 patients underwent US; 38 underwent mammography (MG) and US; and 18 underwent MG, US, and MRI. MG detected 38 cases with a round or oval shape (56%), and mass (89%), were non-circumscribed (62%), hyperdense (53%), and without microcalcifications (95%). Breast US revealed suspicious masses (98%) with a non-circumscribed margin (66%), hypoechogenicity (43%), and intratumoral vascularity (63%). All lesions on breast MRI showed suspicious masses (100%) with ill-defined margins (61%), and 84% showed wash-out kinetics. Benign AMEs showed suspicious features of Breast Imaging Reporting and Data System (BI-RADS) category 4 or 5 in 83%–95% of the MG, US, and MRI. Sixteen of the 41 cases were misdiagnosed on the initial core needle biopsy and two were diagnosed as malignancy. Conclusion Benign breast AME often shows suspicious radiological features mimicking a malignant mass on MG, US, and MRI. Differentiating benign AME from other pathologies might be difficult on core needle biopsy, and complete excision is needed for a correct diagnosis.

The Parathyroid Gland: An Overall Review of the Hidden Organ for Radiologists

Suho Kim,Jung Hee Shin,Soo Yeon Hahn,Haejung Kim,Myoung Kyoung Kim 대한영상의학회 2024 대한영상의학회지 Vol.85 No.2

Parathyroid glands are small endocrine glands that regulate calcium metabolism by producing parathyroid hormone (PTH). These are located at the back of the thyroid gland. Typically, four glands comprise the parathyroid glands, although their numbers may vary among individuals. Parathyroid diseases are related to parathyroid gland dysfunction and can be caused by problems with the parathyroid gland itself or abnormal serum calcium levels arising from renal disease. In recent years, as comprehensive health checkups have become more common, abnormal serum calcium levels are often found incidentally in blood tests, after which several additional tests, including a PTH test, ultrasonography (US), technetium-99m sestamibi parathyroid scan, single-photon-emission CT (SPECT)/CT, four-dimensional CT (4D-CT), and PET/CT, are performed for further evaluation. However, the parathyroid gland remains an organ less familiar to radiologists. Therefore, the normal anatomy, pathophysiology, imaging, and clinical findings of the parathyroid gland and its associated diseases are discussed here.

Three Models for Persuasive Effects of Source Expertise: The Heuristic Cue Model, the Evidence Model, and the Moderator Model

정성은,Christopher J. Carpenter,Haejung Shin,Wonji Lee 한국언론학회 2020 Asian Communication Research Vol.17 No.1

Three models for the effect of source expertise on attitude change, the heuristic cue model, the evidence model, and the moderator model, were identified and tested. To test predictions based on those models, the effect of source expertise on attitude change and on perceived message-effectiveness were examined with different numbers of supporting arguments and different levels of task importance. The main findings of two studies (total N = 342) are that for low task-importance, as the number of supporting arguments increased, perceived message-effectiveness increased then stabilized, and for high task-importance, as the number of supporting arguments increased, the difference in perceived message-effectiveness between high and low source expertise increased. The evidence model and the moderator model received support.

Delayed Cancer Diagnosis in Thyroid Nodules Initially Treated as Benign With Radiofrequency Ablation: Ultrasound Characteristics and Predictors for Cancer

Kim Myoung Kyoung,Shin Jung Hee,Hahn Soo Yeon,Kim Haejung 대한영상의학회 2023 Korean Journal of Radiology Vol.24 No.9

Objective: Regrowth after radiofrequency ablation (RFA) of symptomatic large thyroid nodules, initially treated as benign, sometimes turns out to be malignancies. This study aimed to assess the ultrasound (US) characteristics of thyroid nodules initially treated as benign with RFA and later diagnosed as cancers, predictive factors for cancers masquerading as benign, and methods to avoid RFA in these cancers. Materials and Methods: We reviewed the medical records of 134 consecutive patients with 148 nodules who underwent RFA between February 2008 and November 2016 for the debulking of symptomatic thyroid nodules diagnosed as benign using US-guided biopsy. We investigated the pre-RFA characteristics of the thyroid nodules, changes at follow-up after RFA, and the final surgical pathology. Results: Nodule regrowth after RFA was observed in 36 (24.3%) of the 148 benign nodules. Twenty-two of the 36 nodules were surgically removed, and malignancies were confirmed in seven (19.4% of 36). Of the 22 nodules removed surgically, pre-RFA median volume (range) was significantly larger for malignant nodules than for benign nodules: 22.4 (13.9–84.5) vs. 13.4 (7.3–16.8) mL (P = 0.04). There was no significant difference in the regrowth interval between benign and malignant nodules (P = 0.49). The median volume reduction rate (range) at 12 months was significantly lower for malignant nodules than for benign nodules (51.4% [0–57.8] vs. 83.8% [47.9–89.6]) (P = 0.01). The pre-RFA benignity of all seven malignant nodules was confirmed using two US-guided fine-needle aspirations (FNAs), except for one nodule, which was confirmed using US-guided core-needle biopsy (CNB). Regrown malignant nodules were diagnosed as suspicious follicular neoplasms by CNB. Histological examination of the malignant nodules revealed follicular thyroid carcinomas, except for one follicular variant, a papillary thyroid carcinoma. Conclusion: Symptomatic large benign thyroid nodules showing regrowth or suboptimal reduction after RFA may have malignant potential. The confirmation of these nodules is better with CNB than with FNA.

An examination of work exhaustion in the mobile enterprise environment

Kim, Hyeon Jeong,Lee, Choong C.,Yun, Haejung,Im, Kun Shin Elsevier 2015 TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE Vol.100 No.-

<P><B>Abstract</B></P> <P>As the use of smartphones for work purposes increases, the term of <I>mobile enterprise</I> is emerging and rapidly expanding. The mobile enterprise is defined as a work environment that enables employees to perform their tasks using mobile devices without the constraints of time and space. Mobile enterprise is changing employees' way of working and ultimately affects corporate cultures and business processes as well as working environments. However, mobile enterprise, which was originally adopted to promote organizational efficiency, can intensify employees' work exhaustion. The objective of this study is to provide a better understanding of the work exhaustion in mobile enterprise environment. To that end, inducers and inhibitors of work exhaustion are adopted from previous literature to establish a research model. Mobile enterprise-stressors and organizational supports were used as inducers and inhibitors of work exhaustion, respectively. Job satisfaction was used as a consequence of work exhaustion. In order to empirically test the suggested research model, a survey targeting employees in mobile enterprises was conducted. A total of 210 valid responses were used for path analysis using partial least square (PLS) technique. As expected, we found that while mobile enterprise-stressors (inducers) were positively related to work exhaustion, organizational support (inhibitors) was negatively related to work exhaustion in mobile enterprise environment. These associations were further analyzed at the sub-dimension levels of inducers and inhibitors in order to provide practical implications for minimizing work exhaustion under the mobile enterprise environment. The results revalidated the impacts of techno-stressors and organizational support on work exhaustion in mobile enterprise environment. Some important implications for research and practice as well as directions for future study are discussed.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Inducers and inhibitors of work exhaustion in mobile enterprise are investigated. </LI> <LI> A field survey of 210 individual employees in Korea is conducted. </LI> <LI> Mobile enterprise-stressors (inducers) lead to work exhaustion. </LI> <LI> Organizational supports (inhibitors) reduce work exhaustion. </LI> <LI> In mobile enterprise, work exhaustion reduces job satisfaction. </LI> </UL> </P>

Investigation of the Effective Dose of Agonistic 4-1BB Monoclonal Antibody in a Murine Colon Cancer Metastasis Model

Jong Man Kim,Sung Joo Kim,Jae-Won Joh,Choon Hyuck David Kwon,Haejung Park,Milljae Shin,Eun Young Kim,Ju Ik Moon,Gum O Jung,Gyu-Seong Choi,Suk-Koo Lee 대한외과학회 2010 Annals of Surgical Treatment and Research(ASRT) Vol.78 No.1

Purpose: The aim of this study was to find the dose of agonistic 4-1BB monoclonal antibody (㎃b) that results in optimal T cell activation. Methods: Cancer was induced in mice by an intrahepatic parenchymal injection of 1×10? cells of CT26 cells. Cancer-carrying mice (n=84) were divided into seven groups and treated with either rat IgG or agonistic 4-1BB monoclonal antibody (㎃b) (5㎍, 10㎍, 20㎍, 100㎍, 200㎍, or 300㎍). All treatments were administered intraperitoneally on days 7, 9, and 11. Mice from each group were sacrificed on days 14, 28, and 42. Harvested livers were weighed and the numbers of T cells in the splenocytes were analyzed with a FACS Vantage flow cytometer. Results: Liver weights increased when 5㎍ of agonistic 4-1BB ㎃b was administered, but showed no additional weight increase for doses greater than 10㎍. The absolute numbers of CD4+ and CD8+ T cells increased in groups treated with low doses of agonistic 4-1BB ㎃b (5㎍, 10㎍, or 20㎍), but did not increase in the groups treated with high doses of ㎃b (100㎍, 200㎍, or 300㎍). The levels of CD4/annexin V and CD8/annexin V increased as the dose increased, and the absolute cell numbers of CD4/annexin V were greater than those of CD8/annexin V. Conclusion: Liver weight, including the cancer mass, failed to increase at agonistic 4-1BB ㎃b doses greater than 10㎍. A high dose (≥100㎍) of agonistic 4-1BB ㎃b resulted in lower counts of absolute T cells. This study suggests that a low dose (20㎍) of agonistic 4-1BB ㎃b can be used for optimal T cell activation in combination with other anti-cancer treatments.

국내 식품 중 밥류와 국(탕) 및 찌개류의 수용성 바이타민 B₁, B₂, 그리고 B₃ 함량 검토

김다솜(Da-Som Kim),김회성(Hoe Sung Kim),홍성준(Seong Jun Hong),조진주(Jin-Ju Cho),최미정(Mijung Choi),허성욱(Seong Uk Heo),이주경(Jookyeong Lee),정혜정(Haejung Chung),신의철(Eui-Cheol Shin) 한국식품과학회 2018 한국식품과학회지 Vol.50 No.4

국내 식생활의 가장 기본적인 구성요소인 밥류, 국(탕)류, 그리고 찌개류에 존재하는 다양한 영양성분 중 수용성 바이타민인 B₁ (thiamin), B₂ (riboflavin), 그리고 B₃ (niacin)의 함량을 확인하였다. 밥류의 경우 가공방법에 따른 열처리의 조건이 다양한 수용성 바이타민의 함량을 나타내었고, 국(탕)의 경우 전체적으로 높은 수분함량으로 영양성분의 희석효과가 확인되었고, 찌개의 경우 주재료로 사용된 재료에 따라 다양한 바이타민의 함량을 나타내었다. 본 연구 결과는 국민 식사생활의 영양성분 데이터베이스의 중요한 기초자료로 활용될 것으로 판단되며, 기본 재료가 가진 영양성분의 함량이 가공조건에 따라서 다양한 잔존율을 보인다는 것을 제시하였다. 계속적인 연구를 통하여 셀 수 없이 다양하게 존재하는 한식의 영양성분에 대한 데이터베이스화를 통해 국민 식사생활 개선을 위한 노력이 필요할 것으로 판단된다. A conventional Korean meal includes rice, soups, and stews. The current study investigated the content of water-soluble vitamins B₁ (thiamin), B₂ (riboflavin), and B₃ (niacin) in rice, soups and stews. Reliability of the method used in this study was confirmed based on a control chart. Rice contained 0.007-1.270 mg/100 g of thiamin, 0.010-0.172 mg/100 g of riboflavin, and 0.031-7.582 mg/100 g of niacin. Soups contained 0.036-0.586 mg/100 g of thiamin, 0.008-0.187mg/100 g of riboflavin, and 0.026-9.456 mg/100 g of niacin. Stews contained 0.004-0.704 mg/100 g of thiamin, 0.022- 0.214 mg/100 g of riboflavin, and 0.047-13.118 mg/100 g of niacin. Results of this study may be utilized as a basic database for nutritional content of a Korean meal.