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      • 알레르기성 소인이 없는 정상인에서 특이 알레르겐항체 양성율

        남해선,안현철,박준수,황규윤,박춘식 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

        This study was designed to evaluate prevalence of allergen-specific antibodies in healthy adults. During Mar. ~ Aug. 2001, 1,925 subjects visited for medical check-up, were inquired to fill out a standardized questionnaire. Among them, 200 subjects who had no current and past allergic disorders were randomly selected for rhe current study and examined for allergen-specific antibodies using Korean inhalant panel of MAST-CLA allergen-specific IgE assay. Among them, 170 persons (85.0%) did not have any positive allergen-specific antibody. Each positive rate of 35 allergen specific antibodies was usually less than 3%, except Cockroach Mix (3.5%), Dermatophagoides farinae(8.5%), Dermatophagoides pteronyssinus(6.0%). Among 30 positive subjects, 19(63.3%) showed one or two allergen-specific antibodies. Although atopic subjects in non-allergic population were not common, few of them showed allergen-specific antibodies in Korean inhalant panel of MAST-CLA. Our results suggested that the standardized questionnaire and MAST-CLA could be an useful tool of a screening test for allergy, showing high specificity and sensitivity.

      • 알레르기 환자에서 MAST-CLA 검사의 의의

        남해선,황규윤,,백병준,정윤영,오천환,조성란,박준수 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

        To evaluate usefulness of application of MAST-CLA to indetify allergens, authors conducted MAST-CLA allergen-specific IgE assay and collected allergy related symptoms in 118 allergic patients diagnosed at Soonchunhyang University Chunan Hospital during October 1998 through January 2000. The results were as followings; 1. The mean (SD) age was 23.1 (±12.17) years old and teenagers accounted for 33.1% of patients. 2. The frequent allergic symptoms were sneezing (59.3%), rhinorrhea (53.4%), nasal stiffness (44.1%), itching sensation (24.6%), cough or sputum (16.1%), and eye symptom (8.5%) in order. 3. Among these subjects, 62.7% of patients revealed at least more than one specific allergen and 70.3% showed elevated total IgE levels by MAST-CLA. The three most frequent specific allergens were Dermatophagoides farinae (47.5%), Dermatophagoides pteronyssinus (45.8%), and house dust (30.5%). 4. While age was not significantly related to positive of both specific allergens and total IgE (P>0.05), sneezing and nasal stiffness were significantly associated with positive of specific allergen and total IgE, respectively (both P<0.05). 5. Total IgE increased with the number of specific allergens, but both specific allergen and total IgE were not significantly related to increases of allergic symptoms (P>0.05). In conclusion, our data suggest that MAST-CLA allergen-specific IgE assay is useful measure for identification of causative allergens in allergic patients, however, it is recommended that more specific allergic antigens should be determined and replaced or added to Korean inhalent panel of MAST-CLA.

      • 유아의 자기조절능력과 기질의 관계

        김선혜 원광대학교 대학원 2007 論文集 Vol.38 No.-

        The purpose of this study was to investigate the relationships of young children's self-regulation ability and young children's temperament. The subjects of this study were 81 teachers who teaches five year old children. The kindergarten were located in Jeollabukdo. The instrument of this study were Self-regulation ability, Lee Hyun-Min (1999) modified and used the questionnaires by Kendall & Wilcox(1979), Chun Hui Young's(1993) children temperament scale. The collected data were analyzed by percentage, mean, standard deviation, t-test, correlation analysis. The results of this study were as follows: Firstly, there was a statistically signification difference between boys and girls. Therefor boys had more young children's self-regulation ability than girls. Secondly, there was a statistically signification relationship between young children's self-regulation ability and young children's temperament.

      • 베개내 세균성 내독소와 집먼지진드기 항원 농도의 비교

        남해선 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1

        베개에는 일반적으로 많은 양의 실내 알레르겐과 세균성 내독소가 있는 것으로 알려져 있으며, 이는 집먼지진드기 항원에 감작되어 있는 사람에게는 매우 중요시해야 하는 요소 중의 하나로 되어 있다. 메밀베개는 한국에서는 일반적으로 사용되고 있는 베개이다. 이번 실험을 통하여 메밀베개와 일반 스폰지 베개 내의 집먼지진드기 항원의 양과 내독소의 양이 사용함에 따라 어떻게 변하는지에 대하여 규명해 보고자 천안시에 거주하는 13가구에서 새로 구입하여 지급한 두가지 타입의 베개를 3개월간 같은 침대에서 사용토록한 후 사용전후의 내독소와 집먼지진드기의 양을 서로 비교하였다. 새 베개에서는 두 가지 타입 모두에서 집먼지진드기(Der f 1 및 Der p 1) 항원이 측정되지 않았다. 3개월간 사용한 후에 측정한 Der f 1 의 농도는 메밀베개와 스폰지베개에서 평균이 각각 1,16 g/g (0.02-8.13)와 1.08 g/g (0.19-1.68)로 95% 신뢰구간에서 유의한 차이가 없었다. 그러나 새로 구입한 메밀베개와 스폰지베개에서 측정한 내독소의 양은평균이 각각 60.950 EU/g (30,270-122,700) 와 4,887 EU/g (2,570-9,311) 로 95%의 신뢰구간에서 유의한 차이가 있었다. 3개월간 사용한 후에 측정된 Der f 1 의 양은 메밀베개와 스폰지 베개에서 평균이 각각1.16 g/g (0.02-8.13) 과 1.08 g/g (0.19-1.68) 로 95% 신뢰도 구간에서 유의한 차이가 없었다. 이러한 결과를 통하여 메밀베개는 매우 많은 양의 내독소를 함유하고 있어서 심한 알레르기성 천식의 유발원인이 될 수 있음을 확인하였다.

      • 하수에서 분리한 합성세제 분해균의 특성

        정민선,전진경,정영건,이해경,권오진,지원대,김관배 嶺南大學校 環境問題硏究所 1993 環境硏究 Vol.13 No.1

        대구시와 경산시의 하수에서 음이온계 합성세제인 sodium dodecyl sulfate(SDS)와 sodium dodecylbenzene sulfonate(SDBS)를 유일한 탄소원으로 이용하는 균주 289종을 분리하고 이중 합성세제 분해력이 강한, 그람음성 간균으로 운동성인 8균주를 선정하여 그 선정균들의 특성을 조사하였다. 선정균은 40℃ 이상에서는 생육하지 못하였으며 생육 최적 pH는 균주간에 다소 차이가 있었으며 pH 4.0 이하에서는 선정균 모두 생육치 못하였다. 질소원으로는 SDS분해균의 생육에는 potassium nitrate가, SDBS 분해균의 생육에는 soytone이 좋았다. SDS 분해균인 DS-3, 6, 8, 24 및 SDBS 분해균인 BS-7, 8은 세제농도가 5.0% 이상에서도 생육이 가능하였다. 선정균들은 tetracycline에 감수성이 강한 것으로 나타났지만 penicillin에는 강한 내성을 띠는 것으로 나타났고, ??와 ??금속이온은 모든 선정균들의 생육을 억제하는 것으로 나타났다. On purpose to isolate the organisms, which would utilize detergents(sodium dodecyl sulfate, SDS and sodium dodecylbenzene sulfonate, SDBS) as a sole carbon source, from the waste water of Kyungsan and Taegu city 289 strains were isolated. Among them 8 strains, which are gram negative rods with motility and produce strong enzyme to biodegrade the synthetic detergents, were selected. The characteristics of them were investigated as follows, 8 strains were failed to grow above the temperature of 40℃ and below the pH 4.0 even though they have variable optimum pH. Potassium nitrate was very effective for the growth of SDS-biodegradable strains and soytone was effective for the growth of SDBS-biodegradable strains as a sole nitrogen source. Among 8 strains especially DS-3, DS-6, DS-8 and DS-24(SDS-biodegradation strains) and BS-7 and BS-8(SDBS-biodegradation strains) could grow above 5.0% of detergent concentration. All of 8 strains were very sensitive to tetracycline but resistant to penicillin. Selected 8 strains were inhibited by metal ions of ??(0.156mg/㎖) and ??(0.156mg/㎖).

      • 사파이어 기판에 제작한 YBa₂Cu₃O_(7-δ) 박막의 특성연구

        임해용,김인선,김동호,박종철,박용기 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

        C-axis oriented YBa_(2)Cu_(3)O_(7-δ) (YBCO) thin films on R-cut sapphire substrate were grown by pulsed laser deposition. CeO_(2) film was used as a buffer layer for YBCO deposition on R-cut sapphire substrate. Crystallinity of CeO_(2) buffer layer was researched by XRD. Surface morphology and superconducting properties of YBCO thin films were characterized by SEM and four probe method. Critical temperature of YBCO thin films was ≥89 K, and critical current density was 1.5 x10^(6) A/cm^(2) if at 77 K.

      • 상의에 축적된 세균성 내독소의 양에 대한 조사

        남해선 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

        Environmental endotoxin exposure influences the severity of asthma in house dust mite allergen sensitized subjects. In the domestic environment high levels of endotoxin are present in reservoir floor and bedding dust. Clothing is known to be an important source of allergen exposure, but it is not yet known if this is so for endotoxin. We determined endotoxin levels from winter upper garment clothing with the Limulus amebocyte lysate assay. The geometric mean (95% CI) endotoxin level from 34 colothing items was 17.540 EU/gm. More recently washed clothing (<2 weeks) contained lower endotoxin levels than less frequently washed clothing (>2 weeks), geometric means (95% CI): 9.772 (3,500~28,440) and 20,420 (16,670~24,950) EU/gm dust restectively (p=.017). These levels are high and similar to endotoxin levels from carpets and bedding. This results suggest that clothing is potentially a major source of endotoxin exposure.

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