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An Investigation of Mild Steel with Nitrogen-containing Inhibitor in Hydrochloric Acid
Horng, Y.T.,Tsai, Yi-Liang,Tu, Ching-Fang,Lee, Chien-Ming,Wei, F.I.,Shih, H.C. 한국부식방식학회 2003 Corrosion Science and Technology Vol.2 No.5
Pickling inhibitors can be used to form an adsorbed layer on the metal surface to hinder the discharge of H^+ and dissolution of metal ions. Nitrogen-containing inhibitors were selected as corrosion inhibitors for mild steel (MS) in pickling acid process. In this study, the addition of inhibitor, the pickling temperatures and the pickling times were the parameters to investigate the effects on the inhibition eficiency (IE) for MS by using weight loss measurement. Preliminary results show that the IE increased with the increase in pickling time from 10 minutes to 60 minutes, and the IE also increased with the increase in temperature at room temperature and 40℃. At the higher temperature, the IE values are higher and almost independent with the pickling time. Furthermore, the potentiodynamic polarization, open circuit corrosion potential-time and corrosion current-time studies show that nitorgen-containing inhibitor behaves predominantly as cathodic polarization. The roughness test and SEM investigation are also studied in this papcr.
Go, Y.Y.,Kim, Y.S.,Cheon, S.,Nam, S.,Ku, K.B.,Kim, M.,Cho, N.H.,Park, H.,Alison Lee, P.Y.,Lin, Y.C.,Tsai, Y.L.,Thomas Wang, H.T.,Balasuriya, U.B.R. American Society for Investigative Pathology and t 2017 The Journal of Molecular Diagnostics Vol.19 No.6
<P>Middle East respiratory syndrome (MERS) is an emerging zoonotic viral respiratory disease that was first identified in Saudi Arabia in 2012. In 2015, the largest MERS outbreak outside of the Middle East region occurred in the Republic of Korea. The rapid nosocomial transmission of MERS-coronavirus (MERS-CoV) in Korean health care settings highlighted the importance and urgent need for a rapid and reliable on-site diagnostic assay to implement effective control and preventive measures. Here, the evaluation and validation of two newly developed reverse transcription insulated isothermal PCR (RT-iiPCR) methods targeting the ORF1a and upE genes of MERS-CoV are described. Compared with World Health Organization recommended singleplex real-time quantitative RT-PCR (RT-qPCR) assays, both RT-iiPCR assays had comparable analytical sensitivity for the detection of MERS-CoV RNA in tissue culture fluid and in sputum samples spiked with infectious virus. Furthermore, clinical evaluation was performed with sputum samples collected from subjects with acute and chronic respiratory illnesses, including patients infected with MERS-CoV. The overall agreement values between the two RT-iiPCR assays and the reference RT-qPCR assays were 98.06% (95% CI, 94.43%-100%; K = 0.96) and 99.03% (95% CI, 95.88%-100%; K = 0.99) for ORF1a and upE assays, respectively. The ORF1a and upE MERS-CoV RT-iiPCR assays coupled with a field deployable system provide a platform for a highly sensitive and specific on-site tool for diagnosis of MERS-CoV infections.</P>
Growth of nanocrystalline diamond films on quartz by hot-filament chemical vapor deposition
H. Y. Tsai 한양대학교 세라믹연구소 2015 Journal of Ceramic Processing Research Vol.16 No.5
In this study, a nanocrystalline diamond thin film is applied on a quartz substrate using hot filament chemical vapor deposition (HFCVD) with a mixture of methane and hydrogen gas. Taguchi’s method with L9 (34) orthogonal array is used to design the experimental parameters. Moreover, the effects of the CH4/H2 ratio, the chamber pressure, the substrate temperature, and total gas flow rate on the qualities of the nanocrystalline diamond film are discussed. Film growth rate, surface roughness and transmittance in the visible waveband are considered quality characteristics. With signal-to-noise ratio and the average value of the quality characteristics, optimal parameters can be found. In the analysis of variance and F test, an optimal quality characteristic can be predicted after eliminating factors with less influence. Before the diamond deposition, electrophoresis and Polyetherimide (PEI) adhesion methods as pretreatment on the quartz substrate are compared and discussed for their effects on nucleation density. The optimal parameters obtained in this study are 12% CH4/H2, the chamber pressure of 10 Torr, 600 o C substrate temperature, and total gas flow rate of 100 sccm. With these parameters, the transmittance in the visible waveband of a diamond film on quartz substrate can reach to 60%.
Desmond Y. H. Yap,Kevin S. H. Liu,Yu-Chun Hsu,Grace L. H. Wong,Ming-Chang Tsai,Chien-Hung Chen,Ching-Sheng Hsu,Yee Tak Hui,Michael K. K. Li,Chen-Hua Liu,Yee-Man Kan,Ming-Lung Yu,Man-Fung Yuen 대한간학회 2020 Clinical and Molecular Hepatology(대한간학회지) Vol.26 No.4
Background/Aims: Data on treatment efficacy and safety of glecaprevir/pibrentasvir (GLE/PIB) for chronic hepatitis C virus (HCV) infection in Asian patients with severe renal impairment are limited. This study aimed to study the treatment and side effects of GLE/PIB in these patients infected with non-1 genotype (GT) HCV. Methods: We prospectively recruited patients with Child’s A cirrhosis and eGFR <30 mL/min/1.73 m2 in Hong Kong and Taiwan during 2017–2018 to receive GLE/PIB treatment. Results: Twenty-one patients (GT2, n=7; GT3, n=6; and GT6, n=8) received GLE/PIB for 11.2±1.8 weeks. All except one were treatment-naïve. GLE/PIB was initiated in 16 patients while on dialysis (seven on peritoneal dialysis [PD] and nine on hemodialysis) and in five patients before dialysis. One patient died of PD-related peritonitis during treatment and two were lost to follow up. The SVR12 rate in the remaining 18 patients was 100%. All patients achieved undetectable levels at 4-, 12-, 24- and 48-week after treatment. Patients with deranged alanine aminotransferase showed normalization after 4 weeks and the response was sustained for 48 weeks. No significant adverse event was observed. Conclusions: GLE/PIB treatment was associated with high efficacy and tolerability in HCV-infected patients with severe renal impairment.
Bone Drilling System for Quantifying Hand Feeling in Orthopedic Surgery
( C. -y. Wu ),( J. -y. Su ),( C. -s. Hsu ),( Y. -h. Chen ),( K. -f. Chang ),( C. -c. Huang ),( H. -m. Wu ),( Y. -c. Tsai ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1
In this work, a bone drilling system was designed to quantify “hand feeling”, which can benefit surgeons to be more acquainted with bone hardness. A bi-axial force/torque sensor is mounted on the bone drilling system in order to measure the thrust force and the torque caused by drilling in bones. The system is assembled with a motorized stage, which is directly integrated with a surgical handpiece by an adjustable holder, to drill into various bones (porcine mandible, porcine femur, porcine rib) at different feed speeds and spindle speeds. The results reveal that the feed speed is positively corresponded with force and torque. However, the effect of spindle speed on force and torque is negligible. In addition, drilling bones without spraying water can cause the drilling temperature to increase to 73.3°C. According to the data from the experiments, the exact force and torque during bone drilling can be predicted with the given parameters. Thus, surgeons are capable of preventing the use of excessive force during bone drilling.