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Energy-Efficient Algorithm for Assigning Verification Tasks in Cloud Storage
( Guangwei Xu ),( Zhifeng Sun ),( Cairong Yan ),( Xiujin Shi ),( Yue Li ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.1
Mobile Cloud Computing has become a promising computing platform. It moves users` data to the centralized large data centers for users` mobile devices to conveniently access. Since the data storage service may not be fully trusted, many public verification algorithms are proposed to check the data integrity. However, these algorithms hardly consider the huge computational burden for the verifiers with resource-constrained mobile devices to execute the verification tasks. We propose an energy-efficient algorithm for assigning verification tasks (EEAVT) to optimize the energy consumption and assign the verification tasks by elastic and customizable ways. The algorithm prioritizes verification tasks according to the expected finish time of the verification, and assigns the number of checked blocks referring to devices` residual energy and available operation time. Theoretical analysis and experiment evaluation show that our algorithm not only shortens the verification finish time, but also decreases energy consumption, thus improving the efficiency and reliability of the verification.
Ziyuan Tong,Hang Shen,Ning Shi,Tianjing Wang,Guangwei Bai 한국전자통신연구원 2023 ETRI Journal Vol.45 No.5
A joint resource-optimization scheme is investigated for nonorthogonal multiple access (NOMA)-enhanced scalable video coding (SVC) multicast in unmanned aerial vehicle (UAV)-assisted radio-access networks (RANs). This scheme allows a ground base station and UAVs to simultaneously multicast successive video layers in SVC with successive interference cancellation in NOMA. A video quality-maximization problem is formulated as a mixedinteger nonlinear programming problem to determine the UAV deployment and association, RAN spectrum allocation for multicast groups, and UAV transmit power. The optimization problem is decoupled into the UAV deployment–association, spectrum-partition, and UAV transmit-power–control subproblems. A heuristic strategy is designed to determine the UAV deployment and association patterns. An upgraded knapsack algorithm is developed to solve spectrum partition, followed by fast UAV power fine-tuning to further boost the performance. The simulation results confirm that the proposed scheme improves the average peak signal-to-noise ratio, aggregate videoreception rate, and spectrum utilization over various baselines.
Beyond Canonical PROTAC: Biological targeted protein degradation (bioTPD)
Huifang Wang,Runhua Zhou,Fushan Xu,Kongjun Yang,Liuhai Zheng,Pan Zhao,Guangwei Shi,Lingyun Dai,Chengchao Xu,Le Yu,Zhijie Li,Jianhong Wang,Jigang Wang 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00
Targeted protein degradation (TPD) is an emerging therapeutic strategy with the potential to modulate disease associated proteins that have previously been considered undruggable, by employing the host destructionmachinery. The exploration and discovery of cellular degradation pathways, including but not limited toproteasomes and lysosome pathways as well as their degraders, is an area of active research. Since the conceptof proteolysis-targeting chimeras (PROTACs) was introduced in 2001, the paradigm of TPD has been greatlyexpanded and moved from academia to industry for clinical translation, with small-molecule TPD being particularlyrepresented. As an indispensable part of TPD, biological TPD (bioTPD) technologies including peptide-, fusionprotein-, antibody-, nucleic acid-based bioTPD and others have also emerged and undergone significantadvancement in recent years, demonstrating unique and promising activities beyond those of conventional small molecule TPD. In this review, we provide an overview of recent advances in bioTPD technologies, summarize theircompositional features and potential applications, and briefly discuss their drawbacks. Moreover, we present somestrategies to improve the delivery efficacy of bioTPD, addressing their challenges in further clinical development.
Design and Development of a Single-photon Laser and Infrared Common Aperture Optical System
Wu Hongbo,Zhang Xin,Tan Shuanglong,Liu Mingxin,Wang Lingjie,Yan Lei,Liu Yang,Shi Guangwei 한국광학회 2022 Current Optics and Photonics Vol.6 No.2
A single-photon laser and mid-wave infrared (MWIR) common aperture optical system was designed and developed to detect and range a long-distance civil aviation aircraft. The secondary mirror of the Ritchey-Chretien (R-C) optical system was chosen as a dichroic lens to realize the design of a common aperture system for the laser and MWIR. Point spread function (PSF) ellipticity was introduced to evaluate the coupling efficiency of the laser receiving system. A small aperture stop and narrow filter were set in the secondary image plane and an afocal light path of the laser system, respectively, and the stray light suppression ability of the small aperture stop was verified by modeling and simulation. With high-precision manufacturing technology by single point diamond turning (SPDT) and a high-efficiency dichroic coating, the laser/MWIR common aperture optical system with a φ300 mm aluminum alloy mirror obtained images of buildings at a distance of 5 km with great quality. A civil aviation aircraft detection experiment was conducted. The results show that the common aperture system could detect and track long-distance civil aviation aircraft effectively, and the coverage was more than 450 km (signal-tonoise ratio = 6.3). It satisfied the application requirements for earlier warning and ranging of long-range targets in the area of aviation, aerospace and ground detection systems.